Citation Impact
Citing Papers
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
1992 StandoutNatureNobel
Distinct prion proteins in short and long scrapie incubation period mice
1987 StandoutNobel
Purification and properties of the cellular prion protein from Syrian hamster brain
1992 StandoutNobel
NMR structure of the mouse prion protein domain PrP(121–231)
1996 StandoutNatureNobel
Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication
1990 StandoutNobel
The Genomic Identity of Different Strains of Mouse Scrapie Is Expressed in Hamsters and Preserved on Reisolation in Mice
1989
Successful transmission of Creutzfeldt-Jakob disease from human to mouse verified by prion protein accumulation in mouse brains
1992
Linkage of a prion protein missense variant to Gerstmann–Sträussler syndrome
1989 StandoutNatureNobel
Prion Protein Isoforms, a Convergence of Biological and Structural Investigations
1995 StandoutNobel
Mice with gene targetted prion protein alterations show that Prnp, Sine and Prni are congruent
1998
Structural Clues to Prion Replication
1994 StandoutScienceNobel
Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques
1989 StandoutNobel
Scrapie prion protein contains a phosphatidylinositol glycolipid
1987
Transmissible and non-transmissible amyloidoses: autocatalytic post-translational conversion of host precursor proteins to β-pleated sheet configurations
1988 Nobel
Paradoxical shortening of scrapie incubation times by expression of prion protein transgenes derived from long incubation period mice
1991 StandoutNobel
Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes
1993
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
1995 StandoutNobel
Prion (PrPSc)-specific epitope defined by a monoclonal antibody
1997 StandoutNatureNobel
Mice devoid of PrP are resistant to scrapie
1993 Standout
Non-hydrophobic extracytoplasmic determinant of stop transfer in the prion protein
1990 StandoutNatureNobel
The exceptionally small size of the scrapie agent
1966
Circumventing tolerance to generate autologous monoclonal antibodies to the prion protein.
1996 StandoutNobel
Replication of the Factor in Scrapie Material That Causes a Decrease in Polymorphonuclear Neutrophils
1973
Scrapie-Induced Changes in the Percentage of Polymorphonuclear Neutrophils in Mouse Peripheral Blood
1972
Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice
1997 StandoutNobel
Sedimentation characteristics of the scrapie agent from murine spleen and brain
1978 StandoutNobel
Nature of the Scrapie Agent
1967 Nature
Sedimentation properties of the scrapie agent.
1977
Detection of the Scrapie Agent in Tissues of Normal Mice
1968 Nature
No Mouse PMN Leukocyte Depression after Inoculation with Brain Tissue from Multiple Sclerosis or Spongiform Encephalopathies
1974 StandoutNatureNobel
Linkage of prion protein and scrapie incubation time genes
1986 StandoutNobel
Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice.
1994 StandoutNobel
Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies.
1993 StandoutNobel
Scrapie : A modified membrane hypothesis
1968
Search for Infectious Etiology in Chronic and Subacute Degenerative Diseases of the Central Nervous System
1967
Molecular characteristics of the major scrapie prion protein
1984 StandoutNobel
Oral Transmission of Kuru, Creutzfeldt-Jakob Disease, and Scrapie to Nonhuman Primates
1980
Transmission experiments with multiple sclerosis: an interim report.
1966
Evidence that the Transmission of One Source of Scrapie Agent to Hamsters Involves Separation of Agent Strains from a Mixture
1978
Resistance of the scrapie agent to formalin
1965
EXPERIMENTAL "KURU" IN CHIMPANZEES A Pathological Report
1966
Ultrastructural morphology of amyloid fibrils from neuritic and amyloid plaques
1983
The future of cloning
1999 StandoutNatureNobel
Characteristics of a Short Incubation Model of Scrapie in the Golden Hamster
1977
Primary structure of prion protein may modify scrapie isolate properties.
1989 StandoutNobel
Evidence of mitochondrial involvement in scrapie infection
1989
Studies on the Heat Stability and Chromatographic Behaviour of the Scrapie Agent
1964
Genetical control of the incubation period in mice of the neurological disease, scrapie
1964
Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform.
1995 StandoutNobel
Characterization of Scrapie Infection in Mouse Neuroblastoma Cells
1987
Attempts to release the scrapie agent from tissue debris
1967
Molecular cloning and complete sequence of prion protein cDNA from mouse brain infected with the scrapie agent.
1986
Novel Proteinaceous Infectious Particles Cause Scrapie
1982 StandoutScienceNobel
DNA Synthesis in Scrapie-Affected Mouse Brain
1967
Nature of the Scrapie Agent: Self-replication and Scrapie
1967 Nature
Identification of a Protein That Purifies with the Scrapie Prion
1982 StandoutScienceNobel
Experimental transmission of mouse passaged scrapie to goats, sheep, rats and hamsters
1965
The Scrapie Agent: “A Virus by Any Other Name”
1991
Creutzfeldt-Jakob Disease (Spongiform Encephalopathy): Transmission to the Chimpanzee
1968 StandoutScienceNobel
Evidence for the Conformation of the Pathologic Isoform of the Prion Protein Enciphering and Propagating Prion Diversity
1996 StandoutScienceNobel
TRANSMISSIBLE MINK ENCEPHALOPATHY (TME) IN CHINESE HAMSTERS: IDENTIFICATION OF TWO STRAINS OF TME AND COMPARISONS WITH SCRAPIE
1986
Prion Diseases and the BSE Crisis
1997 StandoutScienceNobel
Three Hamster Species with Different Scrapie Incubation Times and Neuropathological Features Encode Distinct Prion Proteins
1990 StandoutNobel
Genetics and Polymorphism of the Mouse Prion Gene Complex: Control of Scrapie Incubation Time
1988 StandoutNobel
Transmission of chronic spongiform encephalopathy with kuru plaques from humans to small rodents
1979
Propagation of prion strains through specific conformers of the prion protein
1997 StandoutNobel
Transmission of Experimental Kuru to the Spider Monkey ( Ateles geoffreyi )
1968 StandoutScienceNobel
EXPERIMENTAL TRANSMISSION OF SCRAPIE TO GOLDEN HAMSTERS
1963
Slow-Virus Infections of the Nervous System
1967 StandoutNobel
Pathogenesis of mouse scrapie: Effect of route of inoculation on infectivity titres and dose-response curves
1978
Prions
1998 StandoutNobel
Scrapie: A Prototype Slow Infection
1972
Clinical and Histological Observations on Cuprizonc Toxicity and Scrapie in Mice
1971
An experimental examination of the scrapie agent in cell membrane mixtures
1971
Unusual Topogenic Sequence Directs Prion Protein Biogenesis
1990 StandoutScienceNobel
Detection of the Scrapie Agent in Tissues of Normal Mice with Special Reference to the Possibility of Accidental Laboratory Contamination
1971
Genetics and polymorphism of the mouse prion gene complex: control of scrapie incubation time.
1988 StandoutNobel
Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice.
1996
Evidence for synthesis of scrapie prion proteins in the endocytic pathway.
1992 StandoutNobel
Abnormal fibrils from scrapie-infected brain
1981
THE INFECTIVE PROCESS IN SCRAPIE
1968
A cellular gene encodes scrapie PrP 27-30 protein
1985 StandoutNobel
Transmission of Two Subacute Spongiform Encephalopathies of Man (Kuru and Creutzfeldt–Jakob Disease) to New World Monkeys
1971 StandoutNatureNobel
Experimental Scrapie in the Mouse: Electrophoretic and Sedimentation Properties of the Partially Purified Agent
1980 StandoutNobel
Scrapie prion rod formation in vitro requires both detergent extraction and limited proteolysis
1991 StandoutNobel
A comparison of the biochemical changes induced in mouse brain by cuprizone toxicity and by scrapie infection
1974
A Preliminary Report on the Experimental Host Range of the Transmissible Mink Encephalopathy Agent
1969
AMYLOID PLAQUES IN THE BRAINS OF MICE INFECTED WITH SCRAPIE: MORPHOLOGICAL VARIATION AND STAINING PROPERTIES
1975
Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein.
1994 StandoutNobel
Further studies of the infectivity and stability of extracts and homogenates derived from scrapie affected mouse brains
1969
Prions: Novel Infectious Pathogens
1984 StandoutNobel
Identification of prion amyloid filaments in scrapie-infected brain
1985
The Relative Susceptibility of Sheep, Goats and Mice to Two Types of the Goat Scrapie Agent
1966
Accumulation of proteinase K-resistant prion protein (PrP) is restricted by the expression level of normal PrP in mice inoculated with a mouse-adapted strain of the Creutzfeldt-Jakob disease agent
1995
Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene
1986 StandoutNobel
DECREASED PERCENTAGE OF POLYMORPHONUCLEAR NEUTROPHILS IN MOUSE PERIPHERAL BLOOD AFTER INOCULATION WITH MATERIAL FROM MULTIPLE SCLEROSIS PATIENTS
1972
Three hamster species with different scrapie incubation times and neuropathological features encode distinct prion proteins.
1990 StandoutNobel
An analysis of natural scrapie in suffolk sheep
1965
The search for scrapie agent nucleic acid
1990
Molecular Biology of Prion Diseases
1991 StandoutScienceNobel
Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells.
1990 StandoutNobel
Transmissible mink encephalopathy: pathogenesis and nature of the aetiological agent
1972
Prion liposomes
1990 StandoutNobel
A comparison of some biological characteristics of the mouse-passaged scrapie agents, 22A and ME7
1969
Modification of a Strain of Mouse-adapted Scrapie by Passage through Rats
1968
Antibodies to a scrapie prion protein
1984 StandoutNatureNobel
Pathogenesis of mouse scrapie: Dynamics of agent replication in spleen, spinal cord and brain after infection by different routes
1979
Spontaneous Neurodegeneration in Transgenic Mice with Mutant Prion Protein
1990 StandoutScienceNobel
Transmission experiments with a scrapie-like encephalopathy of mink
1970
Experimental Subacute Spongiform Virus Encephalopathies in Primates and Other Laboratory Animals
1973 StandoutScienceNobel
Works of R.L. Chandler being referenced
Virus-like particles from both control and scrapie-affected mouse brain
1977 Nature
Electron microscopic observations on scrapie in the mouse, with reference to glucosaminidase activity.
1968
Cytopathology of Scrapie in the Rat: An Electron Microscopic Study of Thalamic and Hippocampal Areas
1967
EXPERIMENTAL TRANSMISSION OF SCRAPIE TO RATS
1963
Inoculation of Voles, Chinese Hamsters, Gerbils and Guinea-pigs with Scrapie Brain Material
1972
ENCEPHALOPATHY IN MICE PRODUCED BY INOCULATION WITH SCRAPIE BRAIN MATERIAL
1961
Electron Microscopic Observations on Scrapie in the Mouse, with Reference to Glucosaminidase Activity
1968
Experimental Scrapie in the Mouse
1963
ENCEPHALOPATHY IN MICE
1962
FURTHER OBSERVATIONS ON PARTICULATE STRUCTURES IN SCRAPIE AFFECTED BRAIN
1980
Ultrastructural Observations on Scrapie in the Gerbil
1973
Observations on the Comparative Infectivity of Cellular Fractions Derived from Homogenates of Mouse-scrapie Brain
1963