Citation Impact
Citing Papers
Complement and microglia mediate early synapse loss in Alzheimer mouse models
2016 StandoutScience
Germline Transmission and Tissue-Specific Expression of Transgenes Delivered by Lentiviral Vectors
2002 StandoutScienceNobel
Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease
2010 StandoutScience
AMP‐activated protein kinase: a potential player in Alzheimer’s disease
2011
Roles of tau protein in health and disease
2017
Mapping and Quantification of Over 2000 O-linked Glycopeptides in Activated Human T Cells with Isotope-Targeted Glycoproteomics (Isotag)
2018 StandoutNobel
Matrix metalloproteinases and their inhibitors in connective tissue remodeling
1991 Standout
Recruitment of Stem and Progenitor Cells from the Bone Marrow Niche Requires MMP-9 Mediated Release of Kit-Ligand
2002 Standout
The Influence of Chromosomal Location on the Expression of Two Transgenes in Mice
1999 StandoutNobel
Phosphatidylinositol 3-Kinase Activates ERK in Primary Sensory Neurons and Mediates Inflammatory Heat Hyperalgesia through TRPV1 Sensitization
2004
Gene encoding a novel murine tissue inhibitor of metalloproteinases (TIMP), TIMP‐3, is expressed in developing mouse epithelia, cartilage, and muscle, and is located on mouse chromosome 10
1994
Rheumatoid arthritis
2016 Standout
Metformin as a Tool to Target Aging
2016
The role of autophagy in neurodegenerative disease
2013 Standout
Targeting the mouse genome: a compendium of knockouts (part I)
1995
Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy
2012 Standout
Sequestration of dopamine D2 receptors depends on coexpression of
G‐protein‐coupled receptor kinases 2 or 5
1999
MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes
1998 Standout
Structural Principles of Tau and the Paired Helical Filaments of Alzheimer’s Disease
2007
Conditional Forebrain Inactivation of Nicastrin Causes Progressive Memory Impairment and Age-Related Neurodegeneration
2009 StandoutNobel
Metalloproteases and inhibitors in arthritic diseases
2001
Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein
1997 StandoutNature
Pathophysiology of Premature Skin Aging Induced by Ultraviolet Light
1997 Standout
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
2015 Standout
Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations
2005
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Tau phosphorylation: physiological and pathological consequences
2004
Revealing the human mucinome
2022 StandoutNobel
Increased level of active GSK‐3β in Alzheimer’s disease and accumulation in argyrophilic grains and in neurones at different stages of neurofibrillary degeneration
2007
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Genome-Environment Interactions That Modulate Aging: Powerful Targets for Drug Discovery
2011
Chemical design of a radiolabeled gelatinase inhibitor peptide for the imaging of gelatinase activity in tumors
2007
Genetic Mutations Affecting Human Lipoproteins, Their Receptors, and Their Enzymes
1993
Post-translational modifications of tau protein in Alzheimer’s disease
2004
Structural biochemistry and activation of matrix metalloproteases
1993
Fyn Kinase Modulates Synaptotoxicity, But Not Aberrant Sprouting, in Human Amyloid Precursor Protein Transgenic Mice
2004
Glycoproteomics: growing up fast
2020
The Amyloid State of Proteins in Human Diseases
2012 Standout
Membrane-Anchored Aβ Accelerates Amyloid Formation and Exacerbates Amyloid-Associated Toxicity in Mice
2013
Transgenesis in rats: Technical aspects and models
1996
Imaging matrix metalloproteinases in cancer
2008
AKT/PKB Signaling: Navigating the Network
2017 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Dopaminergic Supersensitivity in G Protein-Coupled Receptor Kinase 6-Deficient Mice
2003 StandoutNobel
The Hallmarks of Aging
2013 Standout
A matrix metalloproteinase expressed on the surface of invasive tumour cells
1994 StandoutNature
A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
1997 StandoutNature
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
1996 StandoutNature
Implantation and the placenta: key pieces of the development puzzle
1994 StandoutScience
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers
2007
Amyloid-β/Fyn–Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease
2011
Fibrosis, not cell size, delineates β-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivo
2006 StandoutNobel
Lack of apoA-I is not associated with increased susceptibility to atherosclerosis in mice.
1993
Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease
1997 Standout
Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease
2010 Standout
Genetic Models of Human Vascular Disease
1995 StandoutNobel
Transgenic mouse models of lipoprotein metabolism and atherosclerosis.
1993
Adrenomedullin gene expression differences in mice do not affect blood pressure but modulate hypertension-induced pathology in males
2007 StandoutNobel
Pathology of atheromatous lesions in inbred and genetically engineered mice. Genetic determination of arterial calcification.
1994
3D structure of Alzheimer's amyloid-β(1–42) fibrils
2005 Standout
Synthesis and Characterization of 111In−DTPA−N-TIMP-2: A Radiopharmaceutical for Imaging Matrix Metalloproteinase Expression
2001
Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene
2004 StandoutNobel
Atherosclerosis in mice lacking apo E. Evaluation of lesional development and progression.
1994
TRPV1 Channels Are Intrinsically Heat Sensitive and Negatively Regulated by Phosphoinositide Lipids
2013 StandoutNobel
Generation of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein Template
2012 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
A genetically clamped renin transgene for the induction of hypertension
2002 StandoutNobel
Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function
2005 StandoutScience
Role of Tau Protein in Both Physiological and Pathological Conditions
2004
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization
2010 Standout
Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases
2003 Standout
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
2004 StandoutNobel
Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model
2007 StandoutScience
Matrix Metalloproteinases: A Review
1993 Standout
Targeted disruption of the apolipoprotein C-III gene in mice results in hypotriglyceridemia and protection from postprandial hypertriglyceridemia.
1994
The role of apolipoproteins in lipid metabolism and atherogenesis: aspects in man and mice
1996
Aberrant Activation of Focal Adhesion Proteins Mediates Fibrillar Amyloid β-Induced Neuronal Dystrophy
2003
Gene targeting approaches to complex genetic diseases: atherosclerosis and essential hypertension.
1995 StandoutNobel
Works of Ritchie Williamson being referenced
Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling
2010
Tau binds to phosphatidylinositol-3-kinase, GRB2 phospholipase C gamma-1 and SRC-family kinases through SH3 domain
2002
Lobeline and structurally simplified analogs exhibit differential agonist activity and sensitivity to antagonist blockade when compared to nicotine
1998
A mutant O-GlcNAcase enriches Drosophila developmental regulators
2017
Tyrosine 394 Is Phosphorylated in Alzheimer's Paired Helical Filament Tau and in Fetal Tau with c-Abl as the Candidate Tyrosine Kinase
2005
Tyrosine phosphorylation of tau regulates its interactions with Fyn SH2 domains, but not SH3 domains, altering the cellular localization of tau
2011
In vivo evaluation of 111In-DTPA-N-TIMP-2 in Kaposi sarcoma associated with HIV infection
2001
Neuronal Membranes are Key to the Pathogenesis of Alzheimers Disease: the Role of Both Raft and Non-Raft Membrane Domains
2011
Rapid Tyrosine Phosphorylation of Neuronal Proteins Including Tau and Focal Adhesion Kinase in Response to Amyloid-β Peptide Exposure: Involvement of Src Family Protein Kinases
2002
P38. Matrix metalloproteinases, a target for tumour imaging: In vivo evaluation of radiolabelled N-TIMP2
2000
Disulphide bond assignment in human tissue inhibitor of metalloproteinases (TIMP)
1990
The Microtubule-Associated Protein Tau is Also Phosphorylated on Tyrosine
2009
Marked reduction of high density lipoprotein cholesterol in mice genetically modified to lack apolipoprotein A-I.
1992
Purification of brain D2 dopamine receptor.
1988