Standout Papers
Citation Impact
Citing Papers
Computational protein design enables a novel one-carbon assimilation pathway
2015 StandoutNobel
An Engineered Microbial Platform for Direct Biofuel Production from Brown Macroalgae
2012 StandoutScienceNobel
Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life
2016 StandoutScienceNobel
One thousand plant transcriptomes and the phylogenomics of green plants
2019 StandoutNature
Design, Synthesis, and Biological Evaluation of Hydroquinone Derivatives of 17-Amino-17-demethoxygeldanamycin as Potent, Water-Soluble Inhibitors of Hsp90
2006
A cell-free platform for the prenylation of natural products and application to cannabinoid production
2019 StandoutNobel
Design and synthesis of ansamycin antibiotics
2008
Microbial engineering for the production of advanced biofuels
2012 Nature
Enantioselective, intermolecular benzylic C–H amination catalysed by an engineered iron-haem enzyme
2017 StandoutNobel
Enantioselective Intramolecular CH Amination Catalyzed by Engineered Cytochrome P450 Enzymes In Vitro and In Vivo
2013 StandoutNobel
Molecular mechanisms of antibiotic resistance
2014 Standout
Natural products: A continuing source of novel drug leads
2013 Standout
High‐Throughput Screening for Terpene‐Synthase‐Cyclization Activity and Directed Evolution of a Terpene Synthase
2013 StandoutNobel
Epidermal growth factor receptor mutations in lung cancer
2007 Standout
antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences
2011 Standout
antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters
2015 Standout
Combinatorial biosynthesis of reduced polyketides
2005
HSP90 and the chaperoning of cancer
2005 Standout
A Continuous‐Flow Process for the Synthesis of Artemisinin
2013
Expanding the Enzyme Universe: Accessing Non‐Natural Reactions by Mechanism‐Guided Directed Evolution
2015 StandoutNobel
Antituberculosis drugs: Ten years of research
2007
Anticancer activities of histone deacetylase inhibitors
2006 Standout
The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites
2005
Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization
2018 StandoutNatureNobel
Organocatalytic Enantioselective Decarboxylative Aldol Reaction of Malonic Acid Half Thioesters with Aldehydes
2013 StandoutNobel
Genetically programmed chiral organoborane synthesis
2017 StandoutNatureNobel
Natural products to drugs: natural product-derived compounds in clinical trials
2008 Standout
Metabolic engineering of antibiotic factories: new tools for antibiotic production in actinomycetes
2014
Opportunities and challenges for a sustainable energy future
2012 StandoutNatureNobel
Sequential assembly of the septal cell envelope prior to V snapping in Corynebacterium glutamicum
2019 StandoutNobel
Next generation biofuel engineering in prokaryotes
2013
RACK1 Competes with HSP90 for Binding to HIF-1α and Is Required for O2-Independent and HSP90 Inhibitor-Induced Degradation of HIF-1α
2007 StandoutNobel
Continuous‐Flow Technology—A Tool for the Safe Manufacturing of Active Pharmaceutical Ingredients
2015 Standout
Microbial production of fatty-acid-derived fuels and chemicals from plant biomass
2010 Nature
Improved precursor-directed biosynthesis in E. coli via directed evolution
2010
A synthetic biochemistry platform for cell free production of monoterpenes from glucose
2017
Bioactive jatrophane diterpenes from Euphorbia guyoniana
2009
Exploring the Mechanism Responsible for Cellulase Thermostability by Structure-Guided Recombination
2016 StandoutNobel
Chemoenzymatic preparation of germacrene analogues
2012
Paul Ehrlich's magic bullet concept: 100 years of progress
2008 Standout
What makes a P450 tick?
2013
Improved Cyclopropanation Activity of Histidine‐Ligated Cytochrome P450 Enables the Enantioselective Formal Synthesis of Levomilnacipran
2014 StandoutNobel
A serine-substituted P450 catalyzes highly efficient carbene transfer to olefins in vivo
2013 StandoutNobel
Solid‐Phase Synthesis of Tetrahydro‐β‐carbolines and Tetrahydroisoquinolines by Stereoselective Intramolecular N‐Carbamyliminium Pictet–Spengler Reactions
2006 StandoutNobel
Continuous Flow Reduction of Artemisinic Acid Utilizing Multi‐Injection Strategies—Closing the Gap Towards a Fully Continuous Synthesis of Antimalarial Drugs
2015
Natural products and combinatorial chemistry: back to the future
2004
Molecular mechanisms of antibiotic resistance
2011
Protocols for Implementing an <em>Escherichia coli</em> Based TX-TL Cell-Free Expression System for Synthetic Biology
2013
Applying green chemistry to the photochemical route to artemisinin
2015
The Biosynthetic Logic of Polyketide Diversity
2009 Standout
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Engineering the third wave of biocatalysis
2012 StandoutNature
Field Guide to Plant Model Systems
2016
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Systematic discovery of natural CRISPR-Cas12a inhibitors
2018 StandoutScienceNobel
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Stereoselective Enzymatic Synthesis of Heteroatom-Substituted Cyclopropanes
2018 StandoutNobel
Catalytic Transformation of Lignin for the Production of Chemicals and Fuels
2015 Standout
Enantioselective Imidation of Sulfides via Enzyme-Catalyzed Intermolecular Nitrogen-Atom Transfer
2014 StandoutNobel
Enzymatic construction of highly strained carbocycles
2018 StandoutScienceNobel
Natural Products Version 2.0: Connecting Genes to Molecules
2010
Identification of Mechanism-Based Inactivation in P450-Catalyzed Cyclopropanation Facilitates Engineering of Improved Enzymes
2016 StandoutNobel
Redirecting Photosynthetic Electron Flow into Light-Driven Synthesis of Alternative Products Including High-Value Bioactive Natural Compounds
2013
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Euphorbia Diterpenes: Isolation, Structure, Biological Activity, and Synthesis (2008–2012)
2014 Standout
Asymmetric Enzymatic Synthesis of Allylic Amines: A Sigmatropic Rearrangement Strategy
2016 StandoutNobel
Alternate Heme Ligation Steers Activity and Selectivity in Engineered Cytochrome P450-Catalyzed Carbene-Transfer Reactions
2018 StandoutNobel
Confinement-Controlled, Either syn- or anti-Selective Catalytic Asymmetric Mukaiyama Aldolizations of Propionaldehyde Enolsilanes
2021 StandoutNobel
Industrial biotechnology—the future of green chemistry?
2011
Enzyme-Controlled Nitrogen-Atom Transfer Enables Regiodivergent C–H Amination
2014 StandoutNobel
Photochemical Properties and Reactivity of a Ru Compound Containing an NAD/NADH-Functionalized 1,10-Phenanthroline Ligand
2016 StandoutNobel
Structural Adaptability Facilitates Histidine Heme Ligation in a Cytochrome P450
2015 StandoutNobel
Works of Rika Regentin being referenced
Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin
2012 Standout
Optimizing the heterologous production of epothilone D in Myxococcus xanthus
2002
Modulation of epothilone analog production through media design
2002
High-Level Production of Amorpha-4,11-Diene, a Precursor of the Antimalarial Agent Artemisinin, in Escherichia coli
2009
Control of Secondary Metabolite Congener Distributions via Modulation of the Dissolved Oxygen Tension
2002
Engineered Biosynthesis of Geldanamycin Analogs for Hsp90 Inhibition
2004
Developing an industrial artemisinic acid fermentation process to support the cost‐effective production of antimalarial artemisinin‐based combination therapies
2008
Precursor‐Directed Biosynthesis of 6‐Deoxyerythronolide B Analogs in Streptomycescoelicolor: Understanding Precursor Effects
2000
Production of a novel FK520 analog in Streptomyces hygroscopicus: Improving titer while minimizing impurities
2002
Production of 8-Demethylgeldanamycin and 4,5-Epoxy-8-demethylgeldanamycin from a Recombinant Strain of Streptomyces hygroscopicus
2005