Citation Impact
Citing Papers
Cytokine Storm in a Phase 1 Trial of the Anti-CD28 Monoclonal Antibody TGN1412
2006
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
2003 StandoutNobel
Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti–CTLA-4 antibodies
2009 StandoutNobel
Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma
2013 StandoutNobel
Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity
2013 StandoutScience
High prevalence of low affinity peptide–MHC II tetramer–negative effectors during polyclonal CD4+ T cell responses
2011
Homeostatic maintenance of natural Foxp3 + CD25+ CD4+ regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
2005 StandoutNobel
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model
2007 StandoutNobel
CD4+ Tregs and immune control
2004 StandoutNobel
Re-establishing immunological self-tolerance in autoimmune disease
2012 StandoutNobel
Functional diversity of helper T lymphocytes
1996 StandoutNature
Sequential transcriptional changes dictate safe and effective antigen-specific immunotherapy
2014
Identification of citrullinated vimentin peptides as T cell epitopes in HLA–DR4–positive patients with rheumatoid arthritis
2009
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Exacerbated autoimmunity associated with a T helper‐1 cytokine profile shift in H‐2E‐transgenic mice
1995
Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer
2009
Quantitative Analysis of the T Cell Repertoire that Escapes Negative Selection
1999
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Autoimmune T cell responses in the central nervous system
2009
T Lymphocyte Tolerance: From Thymic Deletion to Peripheral Control Mechanisms
1998
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Mechanisms underlying T-cell tolerance
1996
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Cancer immunotherapy comes of age
2011 StandoutNature
The blockade of immune checkpoints in cancer immunotherapy
2012 Standout
Constitutive Crosspresentation of Tissue Antigens by Dendritic Cells Controls CD8+ T Cell Tolerance In Vivo
2008
Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer
2010 Standout
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
Mechanisms maintaining peripheral tolerance
2009
Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido
2011 StandoutNobel
Impact of Negative Selection on the T Cell Repertoire Reactive to a Self-Peptide
2000
Complement recruitment using bispecific diabodies
1997 StandoutNobel
Enhanced selection of FoxP3 + T-regulatory cells protects CTLA-4-deficient mice from CNS autoimmune disease
2009
Cytokine-Release Syndrome in Patients With B-Cell Chronic Lymphocytic Leukemia and High Lymphocyte Counts After Treatment With an Anti-CD20 Monoclonal Antibody (Rituximab, IDEC-C2B8)
1999
Negative Selection during the Peripheral Immune Response to Antigen
2000
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade
2008 StandoutNobel
Current concepts in the diagnosis and management of cytokine release syndrome
2014 Standout
Adoptive cell transfer as personalized immunotherapy for human cancer
2015 StandoutScience
Dendritic Cells Induce Peripheral T Cell Unresponsiveness under Steady State Conditions in Vivo
2001 StandoutNobel
Type I Diabetes and Multiple Sclerosis Patients Target Islet Plus Central Nervous System Autoantigens; Nonimmunized Nonobese Diabetic Mice Can Develop Autoimmune Encephalitis
2001
Role for IL-10 in Suppression Mediated by Peptide-Induced Regulatory T Cells In Vivo
2003
Immune Tolerance After Delivery of Dying Cells to Dendritic Cells In Situ
2002 StandoutNobel
Cytotoxic T lymphocyte antigen-4 (CTLA-4) limits the expansion of encephalitogenic T cells in experimental autoimmune encephalomyelitis (EAE)-resistant BALB/c mice
2002 StandoutNobel
Synergism of Cytotoxic T Lymphocyte–Associated Antigen 4 Blockade and Depletion of Cd25+ Regulatory T Cells in Antitumor Therapy Reveals Alternative Pathways for Suppression of Autoreactive Cytotoxic T Lymphocyte Responses
2001 StandoutNobel
Cytokine Storm
2020 Standout
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
IL-10-Secreting Regulatory T Cells Do Not Express Foxp3 but Have Comparable Regulatory Function to Naturally Occurring CD4+CD25+ Regulatory T Cells
2004
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
CD4+ Tregs and immune control
2004 StandoutNobel
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
2003 StandoutNobel
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Biology of Oligodendrocyte and Myelin in the Mammalian Central Nervous System
2001 Standout
Prevention of type 1 diabetes in mice by tolerogenic vaccination with a strong agonist insulin mimetope
2011
The future of immune checkpoint therapy
2015 StandoutScienceNobel
Efficient Targeting of Protein Antigen to the Dendritic Cell Receptor DEC-205 in the Steady State Leads to Antigen Presentation on Major Histocompatibility Complex Class I Products and Peripheral CD8+ T Cell Tolerance
2002 StandoutNobel
PD-1 deficiency reveals various tissue-specific autoimmunity by H-2band dose-dependent requirement of H-2g7for diabetes in NOD mice
2008 StandoutNobel
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Antitumor Activity in Melanoma and Anti-Self Responses in a Phase I Trial With the Anti-Cytotoxic T Lymphocyte–Associated Antigen 4 Monoclonal Antibody CP-675,206
2005
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
2010 StandoutNobel
CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit
2008 StandoutNobel
CTLA-4 controls the thymic development of both conventional and regulatory T cells through modulation of the TCR repertoire
2012
CD4+CD25+regulatory T cells limit the risk of autoimmune disease arising from T cell receptor crossreactivity
2005
Tolerogenic Dendritic Cells
2003 StandoutNobel
CCR6 expression defines regulatory effector/memory-like cells within the CD25+CD4+ T-cell subset
2004
Transplantation tolerance induced by intranasal administration of HY peptides
2004
Cancer immunotherapy using checkpoint blockade
2018 StandoutScience
Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4
2013 StandoutNobel
Combination Immunotherapy of B16 Melanoma Using Anti–Cytotoxic T Lymphocyte–Associated Antigen 4 (Ctla-4) and Granulocyte/Macrophage Colony-Stimulating Factor (Gm-Csf)-Producing Vaccines Induces Rejection of Subcutaneous and Metastatic Tumors Accompanied by Autoimmune Depigmentation
1999 StandoutNobel
Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses
2012 StandoutNobel
Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy
1999 StandoutNobel
Works of Richard Smith being referenced
Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion
2004
Low avidity recognition of self-antigen by T cells permits escape from central tolerance
1995
Mechanism of first-dose cytokine-release syndrome by CAMPATH 1-H: involvement of CD16 (FcgammaRIII) and CD11a/CD18 (LFA-1) on NK cells.
1996
Anti-class II MHC antibodies prevent and treat EAE without APC depletion.
1994
Encephalitogenic epitopes of myelin basic protein, proteolipid protein, myelin oligodendrocyte glycoprotein for experimental allergic encephalomyelitis induction in Biozzi ABH (H-2Ag7) mice share an amino acid motif
1996