Citation Impact
Citing Papers
Metastatic Growth from Dormant Cells Induced by a Col-I–Enriched Fibrotic Environment
2010
MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling
2007 StandoutScience
LOX-Mediated Collagen Crosslinking Is Responsible for Fibrosis-Enhanced Metastasis
2013
Cabozantinib (XL184), a Novel MET and VEGFR2 Inhibitor, Simultaneously Suppresses Metastasis, Angiogenesis, and Tumor Growth
2011
Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin
2007
Development of rhabdomyosarcoma in HER-2/neu transgenic p53 mutant mice.
2003
Murine liver repair via transient activation of regenerative pathways in hepatocytes using lipid nanoparticle-complexed nucleoside-modified mRNA
2021 StandoutNobel
Functional Interaction between SEL-10, an F-box Protein, and the Nuclear Form of Activated Notch1 Receptor
2001 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
2010 StandoutNobel
Requirement of Stat3 signaling for HGF/SF-Met mediated tumorigenesis
2002
Targeted Disruption of the Stat1 Gene in Mice Reveals Unexpected Physiologic Specificity in the JAK–STAT Signaling Pathway
1996 Standout
Hepatocellular carcinoma
2003 Standout
Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin
2004 StandoutNobel
Inflammation and cancer
2002 StandoutNature
Stromal fibroblasts in cancer initiation and progression
2004 StandoutNature
Notch signaling is required for normal prostatic epithelial cell proliferation and differentiation
2005
Molecular pathogenesis of human hepatocellular carcinoma
2002
The von Hippel–Lindau tumour suppressor protein: O2 sensing and cancer
2008 StandoutNobel
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
2003 StandoutNobel
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
2007 StandoutNobel
Modulation of Notch Signaling Elicits Signature Tumors and Inhibits Hras1-Induced Oncogenesis in the Mouse Mammary Epithelium
2004
c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention
2004
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Plasticity of tumour and immune cells: a source of heterogeneity and a cause for therapy resistance?
2013
The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo
2003
Cellular expression of estrogen and progesterone receptors in mammary glands: regulation by hormones, development and aging
2002
BRAFE600-associated senescence-like cell cycle arrest of human naevi
2005 StandoutNature
Cellular Senescence in Cancer and Aging
2007 Standout
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
Hepatocellular carcinoma
2012 Standout
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting
2000
Scatter-factor and semaphorin receptors: cell signalling for invasive growth
2002
Stem cells find their niche
2001 StandoutNature
Rhabdomyosarcoma development in mice lacking Trp53 and Fos
2003
Promotion of Hepatocellular Carcinoma by the Intestinal Microbiota and TLR4
2012
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Missing Pieces in the NF-κB Puzzle
2002 Standout
Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function
2004 StandoutNobel
Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding.
1999
Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice
2002
Modulation of Notch signaling by mastermind-like (MAML) transcriptional co-activators and their involvement in tumorigenesis
2004
Distinct Sets of Genetic Alterations in Melanoma
2005 Standout
Notch Signaling in Vertebrate Development and Disease
1997
Discovery of novel c-Met kinase inhibitors bearing a thieno[2,3-d]pyrimidine or furo[2,3-d]pyrimidine scaffold
2011
Hepatocyte growth factor: Renotropic role and potential therapeutics for renal diseases
2001
Malignant melanoma: modern black plague and genetic black box
1998
Emerging Biological Principles of Metastasis
2017 Standout
Mesenchymal Stem Cells Over-expressing Hepatocyte Growth Factor Improve Small-for-size Liver Grafts Regeneration
2007
Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
2008 Standout
Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis
2004 Standout
EMT: 2016
2016 Standout
Asparaginyl Hydroxylation of the Notch Ankyrin Repeat Domain by Factor Inhibiting Hypoxia-inducible Factor
2007 StandoutNobel
Pro-metastatic signaling by c-Met through RAC-1 and reactive oxygen species (ROS)
2006
Met, metastasis, motility and more
2003 Standout
Comparative functional genomics for identifying models of human cancer
2005
Experimental mammary epithelial morphogenesis in anin vivo model: Evidence for distinct cellular progenitors of the ductal and lobular phenotype
1996
Generation of a functional mammary gland from a single stem cell
2006 StandoutNature
Expression of Amino-Terminally Truncated PrP in the Mouse Leading to Ataxia and Specific Cerebellar Lesions
1998
The canonical Notch/RBP-J signaling pathway controls the balance of cell lineages in mammary epithelium during pregnancy
2006 StandoutNobel
Hepatocellular carcinoma pathogenesis: from genes to environment
2006 Standout
TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice
1993 StandoutNobel
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Involvement of cyclooxygenase-2 in gastric mucosal hypertrophy in gastrin transgenic mice
2005
Functional mammary gland development and oncogene-induced tumor formation are not affected by the absence of the retinoblastoma gene
2001
Identification of stem cells in small intestine and colon by marker gene Lgr5
2007 StandoutNature
Chronic liver injury, TGF-β, and cancer
2001
Hepatocyte growth factor promotes cell survival from Fas-mediated cell death in hepatocellular carcinoma cells via Akt activation and Fas-death-inducing signaling complex suppression
2000
Liver regeneration and hepatocarcinogenesis in transforming growth factor-α-targeted mice
1996
Extracellular matrix: A gatekeeper in the transition from dormancy to metastatic growth
2010
Role of YAP/TAZ in mechanotransduction
2011 StandoutNature
Neonatal sunburn and melanoma in mice
2001 Nature
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
The mesenchymal winged helix transcription factor Fkh6 is required for the control of gastrointestinal proliferation and differentiation.
1997
In vivo targeting of SF/HGF and c‐met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis
2001
Cyclin D1 is a candidate oncogene in cutaneous melanoma.
2002
The Gab1 PH Domain Is Required for Localization of Gab1 at Sites of Cell-Cell Contact and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase
1999
Transforming growth factor alpha regulation of two zinc finger-containing immediate early response genes in intestine.
1995
Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation
2003 Standout
Overexpression of transforming growth factor-alpha causes liver enlargement and increased hepatocyte proliferation in transgenic mice.
1994
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence
2007
Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752
2006
The Met pathway: master switch and drug target in cancer progression
2006
A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo.
2003
Hypoxia-Inducible Factor-Dependent Degeneration, Failure, and Malignant Transformation of the Heart in the Absence of the von Hippel-Lindau Protein
2008
Evolution of neoplastic development in the liver of transgenic mice co-expressing c-myc and transforming growth factor-alpha.
1996
The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
2014 Standout
Prions
1998 StandoutNobel
Liver Regeneration
1997 StandoutScience
PAX7 expression in embryonal rhabdomyosarcoma suggests an origin in muscle satellite cells
2003
Metabolic reprogramming and cancer progression
2020 StandoutScience
Multipotential stem cells in adult mouse gastric epithelium
2002
Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells
2010
Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal models
2001
Gastric Hyperplasia and Increased Proliferative Responses of Lymphocytes in Mice Lacking the COOH-terminal Ankyrin Domain of NF-κB2
1997
Essential Role of Gab1 for Signaling by the C-Met Receptor in Vivo
2000
Notch Signaling: Cell Fate Control and Signal Integration in Development
1999 StandoutScience
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
In vivo response of hepatocytes to growth factors requires an initial priming stimulus
1994
Transgenic mouse model for synergistic effects of nuclear oncogenes and growth factors in tumorigenesis: interaction of c-myc and transforming growth factor alpha in hepatic oncogenesis.
1993
Transforming Growth Factor Alpha Dramatically Enhances Oncogene-Induced Carcinogenesis in Transgenic Mouse Pancreas and Liver
1993
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
Works of Richard Sharp being referenced
Identification of VEGF-regulated genes associated with increased lung metastatic potential: functional involvement of tenascin-C in tumor growth and lung metastasis
2008
Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis
2002
Regulation of terminal differentiation of zymogenic cells by transforming growth factor α in transgenic mice
1995
Hypertrophic gastropathy resembling Ménétrier's disease in transgenic mice overexpressing transforming growth factor alpha in the stomach.
1992
Collaboration between growth factors and diverse chemical carcinogens in hepatocarcinogenesis of transforming growth factor alpha transgenic mice.
1993
Transforming growth factor α disrupts the normal program of cellular differentiation in the gastric mucosa of transgenic mice
1995
Transforming growth factor-alpha promotes mammary tumorigenesis through selective survival and growth of secretory epithelial cells.
1995
Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor
1997
Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis.
1996
C-Met Autocrine Activation Induces Development Of Malignant Melanoma And Acquisition Of The Metastatic Phenotype
1998
Hepatocyte growth factor/scatter factor overexpression induces growth, abnormal development, and tumor formation in transgenic mouse livers.
1996
Molecular and genetic analysis of liver oncogenesis in transforming growth factor alpha transgenic mice.
1992