Citation Impact
Citing Papers
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
miR-15 and miR-16 induce apoptosis by targeting BCL2
2005 Standout
A Novel Tankyrase Small-Molecule Inhibitor Suppresses APC Mutation–Driven Colorectal Tumor Growth
2013
The APG8/12-activating Enzyme APG7 Is Required for Proper Nutrient Recycling and Senescence in Arabidopsis thaliana
2002
Genetic Dissection of the Amyloid Precursor Protein in Developmental Function and Amyloid Pathogenesis
2010 StandoutNobel
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Design and Application of an α‐Helix‐Mimetic Scaffold Based on an Oligoamide‐Foldamer Strategy: Antagonism of the Bak BH3/Bcl‐xL Complex
2003
Adaptor protein interactions: modulators of amyloid precursor protein metabolism and Alzheimer's disease risk?
2004
Improved molecular replacement by density- and energy-guided protein structure optimization
2011 StandoutNatureNobel
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
2009 Standout
Small‐Molecule Affinity Ligands for Protein Purification: Combined Computational Enrichment and Automated In‐line Screening of an Optically Encoded Library
2010 StandoutNobel
The Chemical Biology of Apoptosis
2002
IAP-targeted therapies for cancer
2008
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized
2006
Head and neck cancer
2008 Standout
Modulation of Protein–Protein Interactions with Small Organic Molecules
2003
The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions
2002
Targeting protein–protein interactions for cancer therapy
2005
In Vitro Reconstitution of Plant Atg8 and Atg12 Conjugation Systems Essential for Autophagy
2007 StandoutNobel
Application of azide–alkyne cycloaddition ‘click chemistry’ for the synthesis of Grb2 SH2 domain-binding macrocycles
2006
Mechanism of tetracycline resistance by ribosomal protection protein Tet(O)
2013 StandoutNobel
Structural biology of the Bcl-2 family of proteins
2003
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
Cell Death in Pancreatitis
2005
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
New Approaches and Therapeutics Targeting Apoptosis in Disease
2005
Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
2009 Standout
Isosteric exchange of the acylsulfonamide moiety in Abbott’s Bcl-XL protein interaction antagonist
2008
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
2007 StandoutNature
Apop-1, a Novel Protein Inducing Cyclophilin D-dependent but Bax/Bak-related Channel-independent Apoptosis
2006 StandoutNobel
Activating the Wnt/β-Catenin Pathway for the Treatment of Melanoma – Application of LY2090314, a Novel Selective Inhibitor of Glycogen Synthase Kinase-3
2015
Small-molecule inhibitors of protein–protein interactions: progressing towards the dream
2004 Standout
Flotillin-Dependent Clustering of the Amyloid Precursor Protein Regulates Its Endocytosis and Amyloidogenic Processing in Neurons
2008 StandoutNobel
Exploration of Backbone Space in Foldamers Containing α‐ and β‐Amino Acid Residues: Developing Protease‐Resistant Oligomers that Bind Tightly to the BH3‐Recognition Cleft of Bcl‐xL
2007
Strategies for Targeting Protein–Protein Interactions With Synthetic Agents
2005
Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function
2015 Nature
Human Growth Hormone-regulated HOXA1 Is a Human Mammary Epithelial Oncogene
2003
Survey of the year 2003 commercial optical biosensor literature
2004
The exploration of macrocycles for drug discovery — an underexploited structural class
2008
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
The role of autophagy during the early neonatal starvation period
2004 StandoutNatureNobel
Protein Tyrosine Phosphatases in the Human Genome
2004 Standout
AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility
2009 Standout
A Model Binding Site for Testing Scoring Functions in Molecular Docking
2002
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
2006 Standout
PI3K/PTEN signaling in tumorigenesis and angiogenesis
2007
Conformational Changes in Bcl-2 Pro-survival Proteins Determine Their Capacity to Bind Ligands
2009
Advances in targeted therapies for hepatocellular carcinoma in the genomic era
2015
Synthesis of carbazoles and dibenzofurans via cross-coupling of o-iodoanilines and o-iodophenols with silylaryl triflates and subsequent Pd-catalyzed cyclization
2006
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Autophagic Nutrient Recycling in Arabidopsis Directed by the ATG8 and ATG12 Conjugation Pathways
2005
From DARPins to LoopDARPins: Novel LoopDARPin Design Allows the Selection of Low Picomolar Binders in a Single Round of Ribosome Display
2013
Synthesis of Carbazoles by Intramolecular Arylation of Diarylamide Anions
2009
Synthesis of Carbazoles via an Intramolecular Cyclization of 2-(6-Substituted 3(Z)-hexen-1,5-diynyl)anilines and Their Related Molecules
2004
Molecular Recognition of Protein Surfaces: High Affinity Ligands for the CBP KIX Domain
2003
The Bcl-2 family: roles in cell survival and oncogenesis
2003
Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold
2011 StandoutScienceNobel
Reversal of cisplatin resistance with a BH3 mimetic, (−)-gossypol, in head and neck cancer cells: role of wild-type p53 and Bcl-xL
2005
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Information Decay in Molecular Docking Screens against Holo, Apo, and Modeled Conformations of Enzymes
2003
Autophagy Negatively Regulates Cell Death by Controlling NPR1-Dependent Salicylic Acid Signaling during Senescence and the Innate Immune Response inArabidopsis
2009 StandoutNobel
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Docking and scoring in virtual screening for drug discovery: methods and applications
2004 Standout
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
2012 Standout
Folding of Oligoviologens Induced by Radical–Radical Interactions
2014 StandoutNobel
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Protein Tyrosine Phosphatases: Structure and Function, Substrate Specificity, and Inhibitor Development
2002
Highly Oxidized Peroxisomes Are Selectively Degraded via Autophagy in Arabidopsis
2013 StandoutNobel
Strategien zur Modulation von Protein‐Protein‐Wechselwirkungen mit synthetischen Substanzen
2005
Structure-Based Design of Potent, Conformationally Constrained Smac Mimetics
2004
Accurate protein structure modeling using sparse NMR data and homologous structure information
2012 StandoutNobel
Diastereoselective Allylation of Carbonyl Compounds and Imines: Application to the Synthesis of Natural Products
2013 Standout
Structure-based discovery of β 2 -adrenergic receptor ligands
2009 StandoutNobel
Comparative Protein Structure Modeling Using MODELLER
2007 Standout
Cancer Genome Landscapes
2013 StandoutScience
Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells
2015
InCl3-assisted one-pot synthesis of 1-aminocarbazoles
2011
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma
2018 Standout
Handicapping the Race to Develop Inhibitors of the Phosphoinositide 3-Kinase/Akt/Mammalian Target of Rapamycin Pathway
2006
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Synthesis and Applications of tert-Butanesulfinamide
2010
Paralog-Selective Ligands for Bcl-2 Proteins
2005
Processing of ATG8s, Ubiquitin-Like Proteins, and Their Deconjugation by ATG4s Are Essential for Plant Autophagy
2004 StandoutNobel
Comparative Protein Structure Modeling Using Modeller
2006 Standout
Lewis Acid Mediated Aminobenzannulation Reactions of δ‐Ketoalkynes: Synthesis of 1‐Aminocarbazoles and 9‐Aminopyrido[1,2‐a]indoles
2009
Works of Ribo Guo being referenced
Inhibition of AKT survival pathway by a small molecule inhibitor in human endometrial cancer cells
2004
Examination of novel non-phosphorus-containing phosphotyrosyl mimetics against protein-tyrosine phosphatase-1B and demonstration of differential affinities toward Grb2 SH2 domains
2000
Development of a Phosphatase-Stable Phosphotyrosyl Mimetic Suitably Protected for the Synthesis of High-Affinity Grb2 SH2 Domain-Binding Ligands
2002
Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells
2003
Potentiating effect of distant sites in non-phosphorylated cyclic peptide antagonists of the Grb2-SH2 domain
2003
Magnesium-Chelatase from Developing Pea Leaves1
1998
Discovery of Embelin as a Cell-Permeable, Small-Molecular Weight Inhibitor of XIAP through Structure-Based Computational Screening of a Traditional Herbal Medicine Three-Dimensional Structure Database
2004
Discovery of Small-Molecule Inhibitors of Bcl-2 through Structure-Based Computer Screening
2001
Maintenance of adenomatous polyposis coli ( APC )-mutant colorectal cancer is dependent on Wnt/β-catenin signaling
2011
Macrocyclization in the Design of Grb2 SH2 Domain-Binding Ligands Exhibiting High Potency in Whole-Cell Systems
2002