Citation Impact
Citing Papers
High-throughput characterization of protein–protein interactions by reprogramming yeast mating
2017 StandoutNobel
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
A Perfluoroaryl-Cysteine S N Ar Chemistry Approach to Unprotected Peptide Stapling
2013
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Olig2-Regulated Lineage-Restricted Pathway Controls Replication Competence in Neural Stem Cells and Malignant Glioma
2007
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
β-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation
2009 StandoutNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies
2006
Chapter 2 PI3K/PTEN Signaling in Angiogenesis and Tumorigenesis
2009
How the Bcl-2 family of proteins interact to regulate apoptosis
2006
MYC on the Path to Cancer
2012 Standout
Contemporary strategies for the stabilization of peptides in the α-helical conformation
2008
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Gastrointestinal stromal tumour
2007
Regulation of apoptosis: uncovering the binding determinants
2005
Novel mutant-selective EGFR kinase inhibitors against EGFR T790M
2009 StandoutNature
Probing the α‐Helical Structural Stability of Stapled p53 Peptides: Molecular Dynamics Simulations and Analysis
2010
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
2011 StandoutNature
Determinants of BH3 Binding Specificity for Mcl-1 versus Bcl-xL
2010
A Stapled BID BH3 Helix Directly Binds and Activates BAX
2006
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Selective targeting of histone methylation
2011
Autophagy regulates lipid metabolism
2009 StandoutNature
A Selenium Analogue of Firefly D ‐Luciferin with Red‐Shifted Bioluminescence Emission
2012 StandoutNobel
Promoting apoptosis as a strategy for cancer drug discovery
2005
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized
2006
How Can Folded Biopolymers and Synthetic Foldamers Recognize Each Other?
2009
Inhibition of α-helix-mediated protein–protein interactions using designed molecules
2013
BCL-2 family proteins: changing partners in the dance towards death
2017
Angiogenesis: an organizing principle for drug discovery?
2007 Standout
Multiple Interactions Recruit MLL1 and MLL1 Fusion Proteins to the HOXA9 Locus in Leukemogenesis
2010
Solution Structure of Prosurvival Mcl-1 and Characterization of Its Binding by Proapoptotic BH3-only Ligands
2004
Mechanisms of disseminated cancer cell dormancy: an awakening field
2014
Microenvironment Determines Lineage Fate in a Human Model of MLL-AF9 Leukemia
2008
A Membrane-targeted BID BCL-2 Homology 3 Peptide Is Sufficient for High Potency Activation of BAX in Vitro
2006
Tumor‐vascular interactions and tumor dormancy
2008
The kinase inhibitor TKI258 is active against the novel CUX1-FGFR1 fusion detected in a patient with T-lymphoblastic leukemia/lymphoma and t(7;8)(q22;p11)
2011
Conformational Restriction of Peptides Using Dithiol Bis-Alkylation
2016
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
An Electrochemically and Thermally Switchable Donor–Acceptor [c2]Daisy Chain Rotaxane
2014 StandoutNobel
New Approaches and Therapeutics Targeting Apoptosis in Disease
2005
Comparative α‐Helicity of Cyclic Pentapeptides in Water
2014
The immunoglobulin superfamily of neuronal cell adhesion molecules: Lessons from animal models and correlation with human disease
2008
Constraining Cyclic Peptides To Mimic Protein Structure Motifs
2014
Targeting apoptosis in cancer therapy
2020 Standout
Biophysical determinants for cellular uptake of hydrocarbon-stapled peptide helices
2016
BH3 Domains of BH3-Only Proteins Differentially Regulate Bax-Mediated Mitochondrial Membrane Permeabilization Both Directly and Indirectly
2005
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Thermostable red and green light-producing firefly luciferase mutants for bioluminescent reporter applications
2006
Malignant Gliomas in Adults
2008 Standout
Photocontrollable Peptide‐Based Switches Target the Anti‐Apoptotic Protein Bcl‐xL
2008
Emerging Biological Principles of Metastasis
2017 Standout
Direct Targeting of Rab‐GTPase–Effector Interactions
2014
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
The Future of Peptide‐based Drugs
2012 Standout
A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer
2011
Glioma Stem Cells: A Midterm Exam
2008
How Chemoproteomics Can Enable Drug Discovery and Development
2012
Leukaemogenesis: more than mutant genes
2009
Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors
2005
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
Molecular Genetic Pathways as Therapeutic Targets in Acute Myeloid Leukemia
2008
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Is Oncogene Addiction Angiogenesis-dependent?
2005
The Bcl-2 apoptotic switch in cancer development and therapy
2007 Standout
The Hallmarks of Aging
2013 Standout
Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido
2011 StandoutNobel
Life in the balance: how BH3-only proteins induce apoptosis
2005
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Cell of origin determines clinically relevant subtypes of MLL-rearranged AML
2012
Controlling protein assembly on inorganic crystals through designed protein interfaces
2019 StandoutNatureNobel
Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
2006 Standout
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
BCL2 Is a Downstream Effector of MIZ-1 Essential for Blocking c-MYC-induced Apoptosis
2006
Light‐Regulated Stapled Peptides to Inhibit Protein–Protein Interactions Involved in Clathrin‐Mediated Endocytosis
2013
The cancer genome
2009 StandoutNature
An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance
2011
MDGAs interact selectively with neuroligin-2 but not other neuroligins to regulate inhibitory synapse development
2012 StandoutNobel
Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as in Vivo Two-Photon Oxygen Sensors
2015 StandoutNobel
From DARPins to LoopDARPins: Novel LoopDARPin Design Allows the Selection of Low Picomolar Binders in a Single Round of Ribosome Display
2013
Reversible Photocontrol of DNA Binding by a Designed GCN4-bZIP Protein
2006
Emerging Methods and Design Principles for Cell‐Penetrant Peptides
2018
Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes
2012 StandoutNobel
Bidirectional Photomodulation of Surface Tension in Langmuir Films
2016 StandoutNobel
Function-Oriented Synthesis, Step Economy, and Drug Design
2007
Intracellular Delivery of a Proapoptotic Peptide via Conjugation to a RAFT Synthesized Endosomolytic Polymer
2009
Molecular Pathobiology of Gastrointestinal Stromal Sarcomas
2008
α/β-Peptide Foldamers Targeting Intracellular Protein–Protein Interactions with Activity in Living Cells
2015
Light‐Regulated Stapled Peptides to Inhibit Protein–Protein Interactions Involved in Clathrin‐Mediated Endocytosis
2013
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Understanding Cell Penetration of Cyclic Peptides
2019
Folding of Oligoviologens Induced by Radical–Radical Interactions
2014 StandoutNobel
Towards understanding cell penetration by stapled peptides
2014
Macrocyclic Control in Helix Mimetics
2019
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures
2017 StandoutNobel
Engineering Biomolecular Self‐Assembly at Solid–Liquid Interfaces
2020 StandoutNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas
2005
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
SGX393 inhibits the CML mutant Bcr-Abl T315I and preempts in vitro resistance when combined with nilotinib or dasatinib
2008
Diversity-Oriented Stapling Yields Intrinsically Cell-Penetrant Inducers of Autophagy
2017
Catalytic Asymmetric Synthesis of Unprotected β2-Amino Acids
2021 StandoutNobel
MLL leukemia induction by genome editing of human CD34+ hematopoietic cells
2015
Peptide stapling techniques based on different macrocyclisation chemistries
2014
Rapid biocompatible macrocyclization of peptides with decafluoro-diphenylsulfone
2016
Fluorescence Correlation Spectroscopy Reveals Highly Efficient Cytosolic Delivery of Certain Penta-Arg Proteins and Stapled Peptides
2015
Constrained Peptides as Miniature Protein Structures
2012
De Novo Design of Peptide−Calcite Biomineralization Systems
2010
Comparative α‐Helicity of Cyclic Pentapeptides in Water
2014
Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
2012 StandoutNobel
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
Differential Effects of β3‐ versus β2‐Amino Acid Residues on the Helicity and Recognition Properties of Bim BH3‐Derived α/β‐Peptides
2018
Chemical Glycoproteomics
2016 StandoutNobel
Generation of Anti-trypanosomal Agents through Concise Synthesis and Structural Diversification of Sesquiterpene Analogues
2011 StandoutNobel
Development of α-Helical Calpain Probes by Mimicking a Natural Protein–Protein Interaction
2012
Works of Renee D. Wright being referenced
Effects of PKC412, Nilotinib, and Imatinib Against GIST-Associated PDGFRA Mutants With Differential Imatinib Sensitivity
2006
A Novel Noninvasive Model of Endometriosis for Monitoring the Efficacy of Antiangiogenic Therapy
2006
Signature-Based Small Molecule Screening Identifies Cytosine Arabinoside as an EWS/FLI Modulator in Ewing Sarcoma
2007
Increased Neural Cell Adhesion Molecule in the CSF of Patients with Mood Disorder
1996
Further Studies of Elevated Cerebrospinal Fluid Neuronal Cell Adhesion Molecule in Schizophrenia
1998
MLL-AF9 and FLT3 cooperation in acute myelogenous leukemia: development of a model for rapid therapeutic assessment
2007
Monozygotic twins discordant for schizophrenia are discordant for N-CAM and L1 in CSF
1997
Beneficial effects of combining nilotinib and imatinib in preclinical models of BCR-ABL+ leukemias
2006
Prolonged dormancy of human liposarcoma is associated with impaired tumor angiogenesis
2006
Potentiation of antileukemic therapies by the dual PI3K/PDK-1 inhibitor, BAG956: effects on BCR-ABL– and mutant FLT3-expressing cells
2008
Activation of Apoptosis in Vivo by a Hydrocarbon-Stapled BH3 Helix
2004 Science
HOXA9 is required for survival in human MLL-rearranged acute leukemias
2008