Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
2001 StandoutScienceNobel
Role of hypoxia inducible factor-1α in remote limb ischemic preconditioning
2013
Paediatric gastroenterology evaluation of overweight and obese children referred from primary care for suspected non‐alcoholic fatty liver disease
2013
Persistent induction of HIF‐1α and ‐2α in cardiomyocytes and stromal cells of ischemic myocardium
2004
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Cardiomyocyte-specific Prolyl-4-hydroxylase Domain 2 Knock Out Protects from Acute Myocardial Ischemic Injury
2011
Impaired Ca2+-handling in HIF-1α+/− mice as a consequence of pressure overload
2009
Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
2010 StandoutNobel
Keeping the engine primed: HIF factors as key regulators of cardiac metabolism and angiogenesis during ischemia
2007
HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine
2015 StandoutNobel
Role of hypoxia-inducible factor in cell survival during myocardial ischemia–reperfusion
2008
Genetic determinants of hepatic steatosis in man
2011
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Adaptive Myogenesis under Hypoxia
2005
Down-Regulation of Na+/K+ATPase Activity by Human Parvovirus B19 Capsid Protein VP1
2013 Standout
A Comprehensive Review of Noninvasive Liver Fibrosis Tests in Pediatric Nonalcoholic Fatty Liver Disease
2015
Effects of Pulmonary Thromboendarterectomy on Right-Sided Echocardiographic Parameters in Patients With Chronic Thromboembolic Pulmonary Hypertension
2006
Current and Future Management of Chronic Thromboembolic Pulmonary Hypertension: From Diagnosis to Treatment Responses
2006
Efficacy of Inhaled Cannabis on Painful Diabetic Neuropathy
2015
Long-Term Recovery of Exercise Ability After Pulmonary Endarterectomy for Chronic Thromboembolic Pulmonary Hypertension
2006
Outcomes of Pulmonary Endarterectomy Surgery
2006
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
2001 StandoutNobel
Biopsy and Noninvasive Methods to Assess Progression of Nonalcoholic Fatty Liver Disease
2016
Nonalcoholic Steatohepatitis in Children
2009
Association Between Puberty and Features of Nonalcoholic Fatty Liver Disease
2012
Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1α
2001
Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress
2000
Longitudinal analysis of perfusion lung scintigrams of patients with unoperated chronic thromboembolic pulmonary hypertension
2004
Assessment of Operability in Chronic Thromboembolic Pulmonary Hypertension
2006
Genetic Predisposition in NAFLD and NASH: Impact on Severity of Liver Disease and Response to Treatment
2013
Histopathology of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
2015
Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL
2002 StandoutNatureNobel
HIF-1 reduces ischaemia–reperfusion injury in the heart by targeting the mitochondrial permeability transition pore
2014
Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial deficiency of HIF-1
2007 StandoutNobel
Adverse Health Effects of Marijuana Use
2014 Standout
Clinical and histological determinants of nonalcoholic steatohepatitis and advanced fibrosis in elderly patients
2013
Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary disease
2007
Systemic Collateral Supply in Patients with Chronic Thromboembolic and Primary Pulmonary Hypertension: Assessment with Multi–Detector Row Helical CT Angiography
2005
Treatment of Pulmonary Arterial Hypertension
2004 Standout
The efficacy of bosentan in inoperable chronic thromboembolic pulmonary hypertension: a 1-year follow-up study
2006
Increased risk of cardiovascular disease in non-alcoholic fatty liver disease: causal effect or epiphenomenon?
2008
Endpoints and clinical trial design for nonalcoholic steatohepatitis
2011
Carotid Artery Intima-media Thickness in Nonalcoholic Fatty Liver Disease
2008
Histological Abnormalities in Children with Nonalcoholic Fatty Liver Disease and Normal or Mildly Elevated Alanine Aminotransferase Levels
2013
Interventional and surgical modalities of treatment for pulmonary arterial hypertension
2004
Chronic thromboembolic pulmonary hypertension
2018
Performance of ELF Serum Markers in Predicting Fibrosis Stage in Pediatric Non-Alcoholic Fatty Liver Disease
2008
Cellular and molecular pathobiology of pulmonary arterial hypertension
2004 Standout
Pre- and post-conditional inhibition of prolyl-4-hydroxylase domain enzymes protects the heart from an ischemic insult
2015
Cannabinoids for the Treatment of Chronic Non-Cancer Pain: An Updated Systematic Review of Randomized Controlled Trials
2015
Role of NT-proBNP and 6MWD in chronic thromboembolic pulmonary hypertension
2007
Pathological Features of Fatty Liver Disease
2014
Comparison of the Analgesic Effects of Dronabinol and Smoked Marijuana in Daily Marijuana Smokers
2013
HIF-1, O2, and the 3 PHDs
2001 StandoutNobel
A Combination of the Pediatric NAFLD Fibrosis Index and Enhanced Liver Fibrosis Test Identifies Children With Fibrosis
2010
Pulmonary Microvascular Disease in Chronic Thromboembolic Pulmonary Hypertension
2006
Omega-3 Fatty Acids Therapy in Children with Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial
2015
Angiogenesis in health and disease
2003 Standout
Conditional HIF-1α Expression Produces a Reversible Cardiomyopathy
2010
Bosentan Therapy for Inoperable Chronic Thromboembolic Pulmonary Hypertension
2005
Intensive lifestyle treatment for non-alcoholic fatty liver disease in children with severe obesity: inpatient versus ambulatory treatment
2015
The natural history of non-alcoholic fatty liver disease in children: a follow-up study for up to 20 years
2009
The Association of Genetic Variability in Patatin-Like Phospholipase Domain-Containing Protein 3 (PNPLA3) with Histological Severity of Nonalcoholic Fatty Liver Disease†
2010
Hypoxia inducible factor 1 (HIF-1) and cardioprotection
2010
Regulation of angiogenesis by hypoxia: role of the HIF system
2003 StandoutNobel
Levels of Hypoxia-Inducible Factor-1 During Breast Carcinogenesis
2001 StandoutNobel
Pulmonary thromboendarterectomy surgery
2004
Epidemiology and Natural History of Non-Alcoholic Steatohepatitis
2009
Tricuspid valvular disease in the patient with chronic pulmonary thromboembolic disease
2003
Japanese Single-Center Experience of Surgery for Chronic Thromboembolic Pulmonary Hypertension
2006
Modest wine drinking and decreased prevalence of suspected nonalcoholic fatty liver disease
2008
Cellular and Molecular Basis of Pulmonary Arterial Hypertension
2009
CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION
2001
Heritability of Nonalcoholic Fatty Liver Disease
2009
Asymmetric Dimethylarginine Is Increased in Chronic Thromboembolic Pulmonary Hypertension
2007
Risk factors for chronic thromboembolic pulmonary hypertension
2008
Molecular Biology of Chronic Thromboembolic Pulmonary Hypertension
2006
Depletion of PHD3 protects heart from ischemia/reperfusion injury by inhibiting cardiomyocyte apoptosis
2015
Does lowering pulmonary arterial pressure eliminate severe functional tricuspid regurgitation?
2004
CT Scan Findings in Chronic Thromboembolic Pulmonary Hypertension
2005
Medical conditions increasing the risk of chronic thromboembolic pulmonary hypertension
2005
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
2001 StandoutNatureNobel
Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology
2001 StandoutNobel
Mid-term results of surgery for chronic thromboembolic pulmonary hypertension
2009
High prevalence of elevated clotting factor VIII in chronic thromboembolic pulmonary hypertension
2003
Long-term Outcome after Pulmonary Endarterectomy
2008
Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease
2010 Standout
Activation of hypoxia-inducible factor-1 via prolyl-4 hydoxylase-2 gene silencing attenuates acute inflammatory responses in postischemic myocardium
2007
Circulating big endothelin-1: An active role in pulmonary thromboendarterectomy?
2005
Obesity, Inflammation, and Insulin Resistance
2007
Advances in Pediatric Nonalcoholic Fatty Liver Disease†
2009
A novel echocardiographic predictor of in-hospital mortality and mid-term haemodynamic improvement after pulmonary endarterectomy for chronic thrombo-embolic pulmonary hypertension
2007
The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association
2012 Standout
Medical Therapies for Chronic Thromboembolic Pulmonary Hypertension: An Evolving Treatment Paradigm
2006
Unfavourable consequences of chronic cardiac HIF-1α stabilization
2012
Pulmonary endarterectomy is possible and effective without the use of complete circulatory arrest—the UK experience in over 150 patients☆
2008
Lifestyle intervention and antioxidant therapy in children with nonalcoholic fatty liver disease
2008
Obstructive Sleep Apnea and Hypoxemia Are Associated with Advanced Liver Histology in Pediatric Nonalcoholic Fatty Liver Disease
2013
Outcomes of pulmonary endarterectomy for treatment of extreme thromboembolic pulmonary hypertension
2006
Association of clinical features with HLA in chronic pulmonary thromboembolism
2005
Techniques and Outcomes of Pulmonary Endarterectomy for Chronic Thromboembolic Pulmonary Hypertension
2006
Prevalence and risk factors of non-alcoholic fatty liver disease in the elderly: Results from the Rotterdam study
2012
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Pulmonary thromboendarterectomy – risk factors for early survival and hemodynamic improvement
2001
Effect of Vitamin E or Metformin for Treatment of Nonalcoholic Fatty Liver Disease in Children and Adolescents
2011
Pulmonary thromboendarterectomy in patients with chronic thromboembolic pulmonary hypertension: hemodynamic characteristics and changes✩
2000
Chronic Thromboembolic Pulmonary Arterial Hypertension
2004
The changing sensitivity in the life of the nociceptor
1999
Pulmonary endarterectomy: experience and lessons learned in 1,500 cases
2003
Clinical Correlates of Histopathology in Pediatric Nonalcoholic Steatohepatitis
2008
The Prevalence of Non-Alcoholic Fatty Liver Disease in Children and Adolescents: A Systematic Review and Meta-Analysis
2015
Sequence Variations in PCSK9, Low LDL, and Protection against Coronary Heart Disease
2006 Standout
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease
2009
Chronic thromboembolic pulmonary hypertension
2014
Venovenous Extracorporeal Life Support After Pulmonary Endarterectomy: Indications, Techniques, and Outcomes
2006
Stabilization of hypoxia inducible factor rather than modulation of collagen metabolism improves cardiac function after acute myocardial infarction in rats
2006
Discrete changes of cell membrane capacitance observed under conditions of enhanced secretion in bovine adrenal chromaffin cells.
1982 StandoutNobel
Phospholipase A2 Activity-Dependent Stimulation of Ca 2+ Entry by Human Parvovirus B19 Capsid Protein VP1
2006
Nonalcoholic Fatty Liver: A Possible New Target for Type 2 Diabetes Prevention and Treatment
2013
Causes and Metabolic Consequences of Fatty Liver
2008
Pulmonary Vascular Reactivity and Prognosis in Patients With Chronic Thromboembolic Pulmonary Hypertension
2009
Pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension. Ten years experience in Denmark
2005
Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
2002 StandoutNobel
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
2002 StandoutNobel
Spatial distribution of calcium channels and cytosolic calcium transients in growth cones and cell bodies of sympathetic neurons.
1988 StandoutNobel
Accuracy and the effect of possible subject‐based confounders of magnitude‐based MRI for estimating hepatic proton density fat fraction in adults, using MR spectroscopy as reference
2015
Angiotensin-Converting Enzyme Gene Polymorphisms and Prognosis in Chronic Thromboembolic Pulmonary Hypertension
2006
A double‐blind, randomized, placebo‐controlled, parallel group study of THC /CBD spray in peripheral neuropathic pain treatment
2014
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Hypoxia-Inducible Factor 1 and Cardiovascular Disease
2013 StandoutNobel
The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases
2017 Standout
Pulmonary thromboendarterectomy for chronic thromboembolic pulmonary hypertension
2005
Bcl-2-mediated alterations in endoplasmic reticulum Ca 2+ analyzed with an improved genetically encoded fluorescent sensor
2004 StandoutNobel
A Feedback Loop Involving the Phd3 Prolyl Hydroxylase Tunes the Mammalian Hypoxic Response In Vivo
2009 StandoutNobel
Broad Suppression of NADPH Oxidase Activity Exacerbates Ischemia/Reperfusion Injury Through Inadvertent Downregulation of Hypoxia-inducible Factor-1α and Upregulation of Peroxisome Proliferator–activated Receptor-α
2013
Management of Massive and Submassive Pulmonary Embolism, Iliofemoral Deep Vein Thrombosis, and Chronic Thromboembolic Pulmonary Hypertension
2011 Standout
Attenuation of myocardial injury by postconditioning: role of hypoxia inducible factor-1α
2009
Gender Differences in Chronic Thromboembolic Pulmonary Hypertension in Japan
2008
Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin I
2001 StandoutNobel
Hypoxia-Inducible Factor-Dependent Degeneration, Failure, and Malignant Transformation of the Heart in the Absence of the von Hippel-Lindau Protein
2008
Reactivation of Hepatic EPO Synthesis in Mice After PHD Loss
2010 StandoutScienceNobel
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Fatty Liver
2007
Chronic Thromboembolic Pulmonary Hypertension
2006 Standout
Structure of an HIF-1α-pVHL Complex: Hydroxyproline Recognition in Signaling
2002 StandoutScienceNobel
Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure
2007 StandoutNobel
Preoperative Partitioning of Pulmonary Vascular Resistance Correlates With Early Outcome After Thromboendarterectomy for Chronic Thromboembolic Pulmonary Hypertension
2003
Nonalcoholic Fatty Liver Disease: Pathologic Patterns and Biopsy Evaluation in Clinical Research
2012
Human Fatty Liver Disease: Old Questions and New Insights
2011 StandoutScience
Evaluation and Management of the Patient with Pulmonary Arterial Hypertension
2005
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Cannabinoids for Medical Use
2015 Standout
Technique and outcomes of pulmonary endarterectomy surgery.
2008
Hypoxia. 2. Hypoxia regulates cellular metabolism
2010
Different Time Course of Changes in Tricuspid Regurgitant Pressure Gradient and Pulmonary Artery Flow Acceleration After Pulmonary Thromboendarterectomy Implications for Discordant Recovery of Pulmonary Artery Pressure and Compliance
2007
Aortic Pulse-Wave Velocity and Its Relationship to Mortality in Diabetes and Glucose Intolerance
2002 Standout
On the pivotal role of PPARa in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury
2016 StandoutNobel
Cardiac myocyte‐specific HIF‐1α deletion alters vascularization, energy availability, calcium flux, and contractility in the normoxic heart
2004
HIF-1 and human disease: one highly involved factor
2000 StandoutNobel
Reverse right ventricular remodeling after pulmonary endarterectomy
2006
Downregulation of MiR-199a Derepresses Hypoxia-Inducible Factor-1α and Sirtuin 1 and Recapitulates Hypoxia Preconditioning in Cardiac Myocytes
2009
Voltage dependence of K + channels in guard-cell protoplasts
1987 StandoutNobel
Chronic thromboembolic pulmonary hypertension
2004
Signaling and Functions of Angiopoietin-1 in Vascular Protection
2006
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Survival and Quality of Life for Patients With Peripheral Type Chronic Thromboembolic Pulmonary Hypertension
2008
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
Predictors of Outcome in Chronic Thromboembolic Pulmonary Hypertension
2007
Induction of pulmonary hypertension by an angiopoietin 1/TIE2/serotonin pathway
2003
Inhibition of Hypoxia-Inducible Factor Prolyl Hydroxylase Domain Oxygen Sensors: Tricking the Body into Mounting Orchestrated Survival and Repair Responses
2013
Works of Reena Deutsch being referenced
Early Expression of Angiogenesis Factors in Acute Myocardial Ischemia and Infarction
2000
Operative classification of thromboembolic disease determines outcome after pulmonary endarterectomy
2002
Low-Dose Vaporized Cannabis Significantly Improves Neuropathic Pain
2012
Hypoxia-Inducible Factor 1-Alpha Reduces Infarction and Attenuates Progression of Cardiac Dysfunction After Myocardial Infarction in the Mouse
2005
Obesity, insulin resistance, and other clinicopathological correlates of pediatric nonalcoholic fatty liver disease
2003
Signaling Molecules in Nonfamilial Pulmonary Hypertension
2003
Gene transfer of a TIE2 receptor antagonist prevents pulmonary hypertension in rodents
2004
Histopathology of Pediatric Nonalcoholic Fatty Liver Disease * #
2005
Influence of maternal hypercholesterolaemia during pregnancy on progression of early atherosclerotic lesions in childhood: Fate of Early Lesions in Children (FELIC) study
1999
Human Immunodeficiency Virus–1 RNA Levels in Cerebrospinal Fluid Exhibit a Set Point in Clinically Stable Patients Not Receiving Antiretroviral Therapy
2003
Cerebrospinal fluid tau protein is not elevated in HIV-associated neurologic disease in humans
1998
Differential Effects of Metformin and Troglitazone on Cardiovascular Risk Factors in Patients With Type 2 Diabetes
2002
Predictors of Patient Response to Pulmonary Thromboendarterectomy
2000
Prevalence of Fatty Liver in Children and Adolescents
2006
Influence of Gender, Race, and Ethnicity on Suspected Fatty Liver in Obese Adolescents
2005