Standout Papers
- Trp-999 of β-Galactosidase (Escherichia coli) Is a Key Residue for Binding, Catalysis, and Synthesis of Allolactose, the Natural Lac Operon Inducer (2003)
- Thermal denaturation of .beta.-galactosidase and of two site specific mutants (1990)
- Site specific mutants of β-galactosidase show that Tyr-503 is unimportant in Mg2+ binding but that Glu-461 is very important and may be a ligand to Mg2+ (1990)
- Surface denaturation of proteins: the thermal inactivation of β-galactosidase (Escherichia coli) on wall–liquid surfaces (1992)
- Crystallization and 7 Å resolution electron density map of the large fragment of Escherichia coli DNA polymerase I (1983)
Citation Impact
Citing Papers
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
2016 StandoutScienceNobel
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life
2016 StandoutScienceNobel
De novo design of self-assembling helical protein filaments
2018 StandoutScienceNobel
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
The Human SepSecS-tRNA Sec Complex Reveals the Mechanism of Selenocysteine Formation
2009 StandoutScienceNobel
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
2020 StandoutScienceNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
RELION: Implementation of a Bayesian approach to cryo-EM structure determination
2012 Standout
High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy
2013 StandoutNobel
Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP
1985 StandoutNatureNobel
Peptide-binding specificity of the molecular chaperone BiP
1991 StandoutNatureNobel
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
The role of key residues in structure, function, and stability of cytochrome-c
2013
Interior and surface of monomeric proteins
1987
From one amino acid to another: tRNA-dependent amino acid biosynthesis
2008
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Crystal structure of globular domain of histone H5 and its implications for nucleosome binding
1993 StandoutNatureNobel
Semi-automated selection of cryo-EM particles in RELION-1.3
2014
Improvements in protein secondary structure prediction by an enhanced neural network
1990
Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit
2013 StandoutNatureNobel
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
2017 StandoutNatureNobel
Principles for designing ideal protein structures
2012 StandoutNatureNobel
Crystal structure of Thermus aquaticus DNA polymerase
1995 StandoutNatureNobel
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
Structure of the protein subunits in the photosynthetic reaction centre of Rhodopseudomonas viridis at 3Å resolution
1985 StandoutNatureNobel
Design of biologically active binary protein 2D materials
2021 StandoutNatureNobel
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Three-dimensional structure of Escherichia coli RNA polymerase holoenzyme determined by electron crystallography
1989 StandoutNatureNobel
Structure of the mechanically activated ion channel Piezo1
2017 StandoutNatureNobel
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Structure of Taq polymerase with DNA at the polymerase active site
1996 StandoutNatureNobel
Conformations of immunoglobulin hypervariable regions
1989 StandoutNatureNobel
Kemp elimination catalysts by computational enzyme design
2008 StandoutNatureNobel
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
A synthetic homing endonuclease-based gene drive system in the human malaria mosquito
2011 StandoutNatureNobel
The TIM‐barrel fold: a versatile framework for efficient enzymes
2001
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Cryo-EM structure of a type IV secretion system
2022 StandoutNatureNobel
De novo protein design by deep network hallucination
2021 StandoutNatureNobel
Exploitation of binding energy for catalysis and design
2009 StandoutNatureNobel
Inhibitors of Carbohydrate-Processing Enzymes: Design and Synthesis of Sugar-Shaped Heterocycles
1996
PROTEIN FOLDING: The Endgame
1997 StandoutNobel
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Chemical Glycobiology
2001 StandoutScienceNobel
Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning
2015 StandoutScienceNobel
[29] Preparation of selenomethionyl proteins for phase determination
1997
Structure of β-galactosidase at 3.2-Å resolution obtained by cryo-electron microscopy
2014
Genetic and Crystallographic Studies of the 3′,5′-Exonucleolytic Site of DNA Polymerase I
1988 StandoutScienceNobel
Structure of DNA Polymerase I Klenow Fragment Bound to Duplex DNA
1993 StandoutScienceNobel
Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2
2016 Standout
Architecture of RNA Polymerase II and Implications for the Transcription Mechanism
2000 StandoutScienceNobel
Protein production by auto-induction in high-density shaking cultures
2005 Standout
Enzyme-catalyzed synthesis of carbohydrates
1989
Neural Computing in Cancer Drug Development: Predicting Mechanism of Action
1992 StandoutScienceNobel
Structural Basis for the Transition from Initiation to Elongation Transcription in T7 RNA Polymerase
2002 StandoutScienceNobel
Functional Evidence for an RNA Template in Telomerase
1990 StandoutScienceNobel
Domain of E. coli DNA polymerase I showing sequence homology to T7 DNA polymerase
1985 StandoutNatureNobel
The relation between the divergence of sequence and structure in proteins.
1986 Standout
De novo design of protein logic gates
2020 StandoutScienceNobel
The structure, function and evolution of cytochromes
1985
Works of R.E. Huber being referenced
LacZ β‐galactosidase: Structure and function of an enzyme of historical and molecular biological importance
2012
High resolution refinement of β‐galactosidase in a new crystal form reveals multiple metal‐binding sites and provides a structural basis for α‐complementation
2000
Structural comparisons of TIM barrel proteins suggest functional and evolutionary relationships between β‐galactosidase and other glycohydrolases
1999
A quantitation of the factors which affect the hydrolase and transgalactosylase activities of β-galactosidase (E. coli) on lactose
1976
Comparison of the chemical properties of selenocysteine and selenocystine with their sulfur analogs
1967
Some chemical and biochemical properties of selenomethionine
1969
Structure of rice ferricytochrome c at 2·0 Å resolution
1983
Crystallization and 7 Å resolution electron density map of the large fragment of Escherichia coli DNA polymerase I
1983 StandoutNobel
The inhibition of β-galactosidase (Escherichia coli) by amino sugars and amino alcohols
1982
Role of Met-542 as a guide for the conformational changes of Phe-601 that occur during the reaction of β-galactosidase (Escherichia coli)
2010