Citation Impact
Citing Papers
Confirmation of intersubunit connectivity and topology of designed protein complexes by native MS
2018 StandoutNobel
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
Advances in targeted degradation of endogenous proteins
2019
Major advances in targeted protein degradation: PROTACs, LYTACs, and MADTACs
2021
Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies
2020
Chromatin Reader Brd4 Functions in Ig Class Switching as a Repair Complex Adaptor of Nonhomologous End-Joining
2014 StandoutNobel
Targeting the E3 ubiquitin ligases DCAF15 and cereblon for cancer therapy
2020
Structural Basis and Kinetic Pathway of RBM39 Recruitment to DCAF15 by a Sulfonamide Molecular Glue E7820
2019
Unravelling biological macromolecules with cryo-electron microscopy
2016 Nature
Assessing and maximizing data quality in macromolecular crystallography
2015
Molecular mechanisms of cereblon-based drugs
2019
Mass spectrometry guided structural biology
2016
Building ubiquitination machineries: E3 ligase multi-subunit assembly and substrate targeting by PROTACs and molecular glues
2020
Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome
2019
Macromolecularab initiophasing enforcing secondary and tertiary structure
2014
Hallmarks of aging: An expanding universe
2023 Standout
Cereblon modulators: Low molecular weight inducers of protein degradation
2019
Structural Insights into Yeast Telomerase Recruitment to Telomeres
2017
Isopeptide bond in collagen- and fibrinogen-binding MSCRAMMs
2016
Molecular Dynamics Simulation for All
2018 Standout
PROTACs: An Emerging Therapeutic Modality in Precision Medicine
2020
LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation
2021 StandoutNobel
The small regulatory RNA FasX controls pilus expression and adherence in the human bacterial pathogen group A Streptococcus
2012
Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15
2019
Targeted protein degradation: current and future challenges
2020
NEDD8 nucleates a multivalent cullin–RING–UBE2D ubiquitin ligation assembly
2020 Nature
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Rational discovery of molecular glue degraders via scalable chemical profiling
2020
Phenotypic screening with target identification and validation in the discovery and development of E3 ligase modulators
2021
Targeted protein degradation as a powerful research tool in basic biology and drug target discovery
2020
A Glimpse of Structural Biology through X-Ray Crystallography
2014
Targeted protein degradation: expanding the toolbox
2019
The transcription factor code in iPSC reprogramming
2021
PROTAC targeted protein degraders: the past is prologue
2022 Standout
5′ UTR m6A Promotes Cap-Independent Translation
2015 Standout
RNA sequencing uncovers antisense RNAs and novel small RNAs inStreptococcus pyogenes
2015 StandoutNobel
Development of targeted protein degradation therapeutics
2019
Targeting ferroptosis as a vulnerability in cancer
2022 Standout
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
2024 StandoutNobel
Urinary tract infections: epidemiology, mechanisms of infection and treatment options
2015 Standout
Aryl Sulfonamides Degrade RBM39 and RBM23 by Recruitment to CRL4-DCAF15
2019
Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH
2022 StandoutNobel
Harnessing the Power of Proteolysis for Targeted Protein Inactivation
2020
Regulation of Immunoglobulin Class-Switch Recombination
2014
Plasticity in binding confers selectivity in ligand-induced protein degradation
2018
Cancer therapies based on targeted protein degradation — lessons learned with lenalidomide
2021
Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models
2019
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
2016 StandoutNatureNobel
Peptidic degron for IMiD-induced degradation of heterologous proteins
2019 StandoutNobel
Pilin and Sortase Residues Critical for Endocarditis- and Biofilm-Associated Pilus Biogenesis in Enterococcus faecalis
2013
Unifying Catalysis Framework to Dissect Proteasomal Degradation Paradigms
2021
Crystal Engineering of Self-Assembled Porous Protein Materials in Living Cells
2017 StandoutNobel
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures
2017 StandoutNobel
Design of a confined environment using protein cages and crystals for the development of biohybrid materials
2016
The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway
2020
New tools for automated high-resolution cryo-EM structure determination in RELION-3
2018 Standout
Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome
2018
Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2
2016 Standout
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Evolution of Cereblon-Mediated Protein Degradation as a Therapeutic Modality
2019
Works of R.D. Bunker being referenced
Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN
2018 Science
Crystal structure of the human COP9 signalosome
2014 Nature
Crystal Structure of the Minor Pilin FctB Reveals Determinants of Group A Streptococcal Pilus Anchoring
2010
Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism
2012
Cullin–RING ubiquitin E3 ligase regulation by the COP9 signalosome
2016 Nature
Rif1 and Rif2 Shape Telomere Function and Architecture through Multivalent Rap1 Interactions
2013
Mechanisms of OCT4-SOX2 motif readout on nucleosomes
2020 Science
Structural basis for the enhancement of virulence by viral spindles and their in vivo crystallization
2015