Citation Impact
Citing Papers
High-throughput characterization of protein–protein interactions by reprogramming yeast mating
2017 StandoutNobel
Removing T-cell epitopes with computational protein design
2014 StandoutNobel
The use of mRNA display to select high-affinity protein-binding peptides
2001 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicity
2017
EGFR Antagonists in Cancer Treatment
2008 Standout
Targeting hypoxia in cancer therapy
2011 Standout
Development trends for therapeutic antibody fragments
2009
Intratumoral T Cells, Recurrence, and Survival in Epithelial Ovarian Cancer
2003 Standout
Targeting by affinity–matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform
1997 StandoutNobel
Improving Protein Pharmacokinetics by Genetic Fusion to Simple Amino Acid Sequences
2004
Retargeting serum immunoglobulin with bispecific diabodies
1997 StandoutNobel
Antibody engineering and modification technologies
2007
Disrupting tumour blood vessels
2005
Combining vascular and cellular targeting regimens enhances the efficacy of photodynamic therapy
2005
Selective activation of anticancer prodrugs by monoclonal antibody–enzyme conjugates
2001
Purification of bacterially expressed single chain Fv antibodies for clinical applications using metal chelate chromatography
1995
Clinical evidence of efficient tumor targetting based on single–chain Fv antibody selected from a combinatorial library
1996
Specialization of tumour vasculature
2002
Tumor metastasis: moving new biological insights into the clinic
2013
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
Evolution of a designed protein assembly encapsulating its own RNA genome
2017 StandoutNatureNobel
[5] Screening of phage antibody libraries
1996 StandoutNobel
Antibody phage display technology and its applications
1998
The biology of the combretastatins as tumour vascular targeting agents
2002
Human Antibodies with Sub-nanomolar Affinities Isolated from a Large Non-immunized Phage Display Library
1996
Combined sonodynamic and antimetabolite therapy for the improved treatment of pancreatic cancer using oxygen loaded microbubbles as a delivery vehicle
2015
All-Optical Histology Using Ultrashort Laser Pulses
2003 StandoutNobel
Construction of di-scFv through a trivalent alkyne–azide 1,3-dipolar cycloaddition
2006
Emerging Biological Principles of Metastasis
2017 Standout
Calmodulin as a Versatile Tag for Antibody Fragments
1995 StandoutNobel
Vascular‐targeting therapies for treatment of malignant disease
2004
Paclitaxel plus Bevacizumab versus Paclitaxel Alone for Metastatic Breast Cancer
2007 Standout
Recombinant antibody fragments
1998
PET of Hypoxia with89Zr-Labeled cG250-F(ab′)2in Head and Neck Tumors
2010
Recombinant Human Single Chain Fv Antibodies Recognizing Human Interleukin-6
1998 StandoutNobel
Therapeutic antibody fragments with prolonged in vivo half-lives
1999
Dynamic Combinatorial Chemistry Employing Boronic Acids/Boronate Esters Leads to Potent Oxygenase Inhibitors
2012 StandoutNobel
Ligand-targeted therapeutics in anticancer therapy
2002
Protein‐ and peptide‐modified synthetic polymeric biomaterials
2010
Liposomal drug delivery systems: From concept to clinical applications
2012 Standout
Exploring protein fitness landscapes by directed evolution
2009 StandoutNobel
Pharmacokinetic and biodistribution properties of poly(ethylene glycol)–protein conjugates
2003
Efficient one-step direct labelling of recombinant antibodies with technetium-99m
1995
Radioactive labeling of recombinant antibody fragments by phosphorylation using human casein kinase II and [γ-32P]-ATP
1996 StandoutNobel
Angiogenesis as a therapeutic target
2005 StandoutNature
Tumor Angiogenesis
2008 Standout
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
Renal clearance of quantum dots
2007 StandoutNobel
Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity
2000
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
2018 StandoutNobel
RNA-peptide fusions for the in vitro selection of peptides and proteins
1997 StandoutNobel
Vascular Targeting Agents as Cancer Therapeutics
2004
Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics
2005 StandoutScience
Radiometal labeling of recombinant proteins by a genetically engineered minimal chelation site: technetium-99m coordination by single-chain Fv antibody fusion proteins through a C-terminal cysteinyl peptide.
1995
Minibody: A novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts.
1996
Compact Cysteine-Coated CdSe(ZnCdS) Quantum Dots for in Vivo Applications
2007 StandoutNobel
Imaging Tumors with an Albumin-Binding Fab, a Novel Tumor-Targeting Agent
2007
Hypochlorous Acid Promoted Platinum Drug Chemotherapy by Myeloperoxidase-Encapsulated Therapeutic Metal Phenolic Nanoparticles
2018
Vascular Permeability Factor/Vascular Endothelial Growth Factor: A Critical Cytokine in Tumor Angiogenesis and a Potential Target for Diagnosis and Therapy
2002
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Effect of molecular size of pegylated peptide on the pharmacokinetics and tumor targeting in lymphoma-bearing mice.
2003
Drug Discovery: A Historical Perspective
2000 StandoutScience
Single-nanometer iron oxide nanoparticles as tissue-permeable MRI contrast agents
2021 StandoutNobel
Drug Delivery Systems: Entering the Mainstream
2004 StandoutScience
About Dendrimers: Structure, Physical Properties, and Applications
1999 Standout
Chimeric Antigen Receptor Therapy
2018 Standout
Synthesis of an organoinsulin molecule that can be activated by antibody catalysis
2001 StandoutNobel
The development of [(124)I]iodinated-VG76e: a novel tracer for imaging vascular endothelial growth factor in vivo using positron emission tomography.
2002
Metabolic reprogramming and cancer progression
2020 StandoutScience
Molecularly Imprinted Polymers and Their Use in Biomimetic Sensors
2000 Standout
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy
2005 StandoutScience
Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization
2010 Standout
Antibody–Enzyme Fusion Proteins for Cancer Therapy
2011
Synthesis and characterization of polymer-(multi)-peptide conjugates for control of specific cell aggregation
1998
Designing Cell-Compatible Hydrogels for Biomedical Applications
2012 StandoutScience
Antibody Fragments in Tumor Pretargeting. Evaluation of Biotinylated Fab‘ Colocalization with Recombinant Streptavidin and Avidin
1996
Emerging Targets in Photopharmacology
2016 StandoutNobel
Antibody-directed enzyme prodrug therapy (ADEPT): a review
1997
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Multiple event activation of a generic prodrug trigger by antibody catalysis
1999 StandoutNobel
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
CAR T cell immunotherapy for human cancer
2018 StandoutScience
Second-Generation Difluorinated Cyclooctynes for Copper-Free Click Chemistry
2008 StandoutNobel
A detailed examination of boronic acid–diol complexation
2002
Fast detection of liver fibrosis with collagen-binding single-nanometer iron oxide nanoparticles via T 1 -weighted MRI
2023 StandoutNobel
Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers
2018
Genetically engineered tetravalent single-chain Fv of the pancarcinoma monoclonal antibody CC49: improved biodistribution and potential for therapeutic application.
2000
A β-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy
2005
Works of RB Pedley being referenced
Ablation of colorectal xenografts with combined radioimmunotherapy and tumor blood flow-modifying agents.
1996
A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer
2015
Dosimetric evaluation and radioimmunotherapy of anti-tumour multivalent Fab′ fragments
1999
Clinical Applications of Phage‐Derived sFvs and sFv Fusion Proteins
2000
In vitro and in vivo characterisation of a recombinant carboxypeptidase G2::anti-CEA scFv fusion protein
1996
In vivo imaging of glucose uptake and metabolism in tumors
2013
Tumour targeting of humanised cross-linked divalent-fab′ antibody fragments: a clinical phase I/II study
2002
Clearance mechanism of a mannosylated antibody–enzyme fusion protein used in experimental cancer therapy
2006
Differential sensitivity of two adenocarcinoma xenografts to the anti‐vascular drugs combretastatin A4 phosphate and 5,6‐dimethylxanthenone‐4‐acetic acid, assessed using MRI and MRS
2002
From laboratory to Phase I/II cancer trials with recombinant biotherapeutics
2007
Localisation of monoclonal antibodies reacting with different epitopes on carcinoembryonic antigen (CEA) – implications for targeted therapy
1994
Preparation, characterisation and tumour targeting of cross-linked divalent and trivalent anti-tumour Fab' fragments
1996
Synergy between vascular targeting agents and antibody-directed therapy
2002
Antigen specificity and tumour targeting efficiency of a human carcinoembryonic antigen-specific scFv and affinity-matured derivatives
1998
Human monoclonal antibodies targeting carbonic anhydrase IX for the molecular imaging of hypoxic regions in solid tumours
2009
Novel Prodrugs of Alkylating Agents Derived from 2-Fluoro- and 3-Fluorobenzoic Acids for Antibody-Directed Enzyme Prodrug Therapy
1994
Galactosylated streptavidin for improved clearance of biotinylated intact and F(ab')2 fragments of an anti-tumour antibody
1995
A single chain Fv derived from a filamentous phage library has distinct tumour targeting advantages over one derived from a hybridoma
1995
Phage libraries for generation of clinically useful antibodies
1994 StandoutNobel
Enhanced tumour specificity of an anti-carcinoembrionic antigen Fab' fragment by poly(ethylene glycol) (PEG) modification
1996
Drug Delivery Strategies for Platinum-Based Chemotherapy
2017
Eradication of colorectal xenografts by combined radioimmunotherapy and combretastatin a-4 3-O-phosphate.
2001
Enhancement of antibody-directed enzyme prodrug therapy in colorectal xenografts by an antivascular agent.
1999
The potential for enhanced tumour localisation by poly(ethylene glycol) modification of anti-CEA antibody
1994
Sustained Tumor Regression of Human Colorectal Cancer Xenografts Using a Multifunctional Mannosylated Fusion Protein in Antibody-Directed Enzyme Prodrug Therapy
2005
A strategy for antitumor vascular therapy by targeting the vascular endothelial growth factor: receptor complex.
2001
Improved tumor targeting with chemically cross-linked recombinant antibody fragments.
1994