Citation Impact
Citing Papers
Antagonistic roles of full-length N-cadherin and its soluble BMP cleavage product in neural crest delamination
2006
Chibby cooperates with 14-3-3 to regulate β-catenin subcellular distribution and signaling activity
2008
Bcl9/Bcl9l Are Critical for Wnt-Mediated Regulation of Stem Cell Traits in Colon Epithelium and Adenocarcinomas
2010
Targeted Disruption of the BCL9/β-Catenin Complex Inhibits Oncogenic Wnt Signaling
2012
A role of Pygopus as an anti-repressor in facilitating Wnt-dependent transcription
2008
Decoding of Methylated Histone H3 Tail by the Pygo-BCL9 Wnt Signaling Complex
2008
Novel TCF‐binding sites specify transcriptional repression by Wnt signalling
2008
Wnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling
2014
mTOR Signaling in Growth Control and Disease
2012 Standout
Caspase-2 deficiency promotes aberrant DNA-damage response and genetic instability
2012
Caspase-2: the orphan caspase
2011
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Caenorhabditis elegans pathways that surveil and defend mitochondria
2014 StandoutNatureNobel
Wnt/β-catenin signaling: new (and old) players and new insights
2008
Wnt signaling in cancer
2016 Standout
The DNA Damage Response Kinases DNA-dependent Protein Kinase (DNA-PK) and Ataxia Telangiectasia Mutated (ATM) Are Stimulated by Bulky Adduct-containing DNA
2011 StandoutNobel
The APC tumor suppressor counteracts β-catenin activation and H3K4 methylation at Wnt target genes
2006
β-Catenin hits chromatin: regulation of Wnt target gene activation
2009
Wnt signaling: is the party in the nucleus?
2006
WNT signalling pathways as therapeutic targets in cancer
2012 Standout
PUMA, a potent killer with or without p53
2008
In Silico Analysis of Kinase Expression Identifies WEE1 as a Gatekeeper against Mitotic Catastrophe in Glioblastoma
2010
New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer
2018 Standout
Mining the Wnt pathway for cancer therapeutics
2006
Designed Armadillo Repeat Proteins as General Peptide-Binding Scaffolds: Consensus Design and Computational Optimization of the Hydrophobic Core
2008
Genome-Wide Analysis of Light- and Temperature-Entrained Circadian Transcripts in Caenorhabditis elegans
2010 StandoutNobel
A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging
2009
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
WNT signaling in bone homeostasis and disease: from human mutations to treatments
2013 Standout
Parafibromin/Hyrax Activates Wnt/Wg Target Gene Transcription by Direct Association with β-catenin/Armadillo
2006
Modern human changes in regulatory regions implicated in cortical development
2020
PTH/cAMP/PKA signaling facilitates canonical Wnt signaling via inactivation of glycogen synthase kinase‐3β in osteoblastic Saos‐2 cells
2007 StandoutNobel
Wnt Signaling from Development to Disease: Insights from Model Systems
2009
C‐terminal‐binding protein directly activates and represses Wnt transcriptional targets in Drosophila
2006
Wnt/β-Catenin Signaling and Disease
2012 Standout
Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
2009 Standout
Caspase Functions in Cell Death and Disease
2013 Standout
mTOR: from growth signal integration to cancer, diabetes and ageing
2010 Standout
A Wnt kinase network alters nuclear localization of TCF-1 in colon cancer
2009 StandoutNobel
Wingless-Independent Association of Pygopus with dTCF Target Genes
2007
Programmed Cell Senescence during Mammalian Embryonic Development
2013 Standout
EMT: 2016
2016 Standout
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
2011 Standout
Argonaute CLIP Defines a Deregulated miR-122-Bound Transcriptome that Correlates with Patient Survival in Human Liver Cancer
2017 StandoutNobel
Oxidative Stress in Cancer
2020 Standout
SnapShot: Wnt/β-Catenin Signaling
2007
Activation of apoptosis signalling pathways by reactive oxygen species
2016 Standout
BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration
2009
Wnt/β-Catenin Signaling in Development and Disease
2006 Standout
Inflammatory caspases are innate immune receptors for intracellular LPS
2014 StandoutNature
Targeting DNA repair mechanisms in cancer
2012
Cell Cycle Control of Wnt Receptor Activation
2009
Activation of Wingless Targets Requires Bipartite Recognition of DNA by TCF
2008
Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition
2016 StandoutNobel
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Probing the canonicity of the Wnt/Wingless signaling pathway
2017
Caspase-2: killer, savior and safeguard—emerging versatile roles for an ill-defined caspase
2009
The Hallmarks of Aging
2013 Standout
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
2009 Standout
Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis
2012 Standout
Post-transcriptional Wnt Signaling Governs Epididymal Sperm Maturation
2015
Exploring the repeat protein universe through computational protein design
2015 StandoutNatureNobel
Notch: Architect, Landscaper, and Guardian of the Intestine
2011 Standout
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
The unpredictable caspase-2: what can it do?
2010
Receptor subtype discrimination using extensive shape complementary designed interfaces
2019 StandoutNobel
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Fine-tuning of nuclear β-catenin by Chibby and 14-3-3
2009
Neutrophil recruitment and function in health and inflammation
2013 Standout
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
A General Computational Approach for Repeat Protein Design
2014 StandoutNobel
New Insights into Checkpoint Kinase 1 in the DNA Damage Response Signaling Network
2010
Mastermind-like 1 Is a Specific Coactivator of β-Catenin Transcription Activation and Is Essential for Colon Carcinoma Cell Survival
2007
An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/ wingless signaling pathway
2011
Genetic Control of Programmed Cell Death During Animal Development
2009
Endocardial and Epicardial Epithelial to Mesenchymal Transitions in Heart Development and Disease
2012
p53 and Ceramide as Collaborators in the Stress Response
2013
Activation of hypoxia-inducible factor-1α (Hif-1α) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model
2011
Nucleo-cytoplasmic distribution of β-catenin is regulated by retention
2006
Pygopus activates Wingless target gene transcription through the mediator complex subunits Med12 and Med13
2008
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Homeodomain-interacting protein kinases (Hipks) promote Wnt/Wg signaling through stabilization of β-catenin/Arm and stimulation of target gene expression
2008
Cell-Type-Specific Function of BCL9 Involves a Transcriptional Activation Domain That Synergizes with β-Catenin
2008
Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole–cilium interface and facilitates proper cilium formation and function
2014 StandoutNobel
Specific apoptosis induction by the dual PI3K/mTor inhibitor NVP-BEZ235 in HER2 amplified and PIK3CA mutant breast cancer cells
2009
Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF
2014
Caspase-2 at a glance
2012
The Role of Wnt Signaling in Physiological and Pathological Angiogenesis
2010
Nuclear-Cytoplasmic Shuttling of Chibby Controls β-Catenin Signaling
2009
Tunable protein synthesis by transcript isoforms in human cells
2016 StandoutNobel
Wingless Signaling Induces Widespread Chromatin Remodeling of Target Loci
2007
A tumor suppressor function for caspase-2
2009
Works of Raymond Hoffmans being referenced
Identification and in vivo role of the Armadillo-Legless interaction
2004
Probing transcription-specific outputs of β-catenin in vivo
2011
BCL9-2 binds Arm/β-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling
2006
Transcription under the Control of Nuclear Arm/β-Catenin
2006
Chk1 Suppresses a Caspase-2 Apoptotic Response to DNA Damage that Bypasses p53, Bcl-2, and Caspase-3
2008
Pygopus and Legless Provide Essential Transcriptional Coactivator Functions to Armadillo/β-Catenin
2005
Wnt/β-Catenin Signaling Regulates Sequential Fate Decisions of Murine Cortical Precursor Cells
2014