Citation Impact
Citing Papers
Inhibition of Wee1 Sensitizes Cancer Cells to Antimetabolite Chemotherapeutics In Vitro and In Vivo , Independent of p53 Functionality
2013
Removing T-cell epitopes with computational protein design
2014 StandoutNobel
The Dual Pathway Inhibitor Rigosertib Is Effective in Direct Patient Tumor Xenografts of Head and Neck Squamous Cell Carcinomas
2013
Combined Inhibition of Wee1 and PARP1/2 for Radiosensitization in Pancreatic Cancer
2014
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
2009 StandoutScience
A Biomarker-enriched, Randomized Phase II Trial of Adavosertib (AZD1775) Plus Paclitaxel and Carboplatin for Women with Platinum-sensitive TP53 -mutant Ovarian Cancer
2020
Imaging Tetrahymena ribozyme splicing activity in single live mammalian cells
2003 StandoutNobel
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor
2002 StandoutScience
DNA Damage Produced by Ionizing Radiation in Mammalian Cells: Identities, Mechanisms of Formation, and Reparability
1988
Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli
1976
The DNA-damage response in human biology and disease
2009 StandoutNature
Endogenous human microRNAs that suppress breast cancer metastasis
2008 StandoutNature
Apoptosis. Its significance in cancer and cancer Therapy
1994 Standout
Phthalazinones. Part 1: The design and synthesis of a novel series of potent inhibitors of poly(ADP-ribose)polymerase
2005
X-irradiation causes a prolonged reduction in cell proliferation in the dentate gyrus of adult rats
2000
Histone deacetylases and cancer
2007
Synergistic antitumor interactions between MK-1775 and panobinostat in preclinical models of pancreatic cancer
2014
Carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone (FCCP) as an O2− generator induces apoptosis via the depletion of intracellular GSH contents in Calu-6 cells
2008
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Risk of Stevens-Johnson syndrome and toxic epider mal necrolysis during first weeks of antiepileptic therapy: a case-control study
1999
The relationship between apoptosis and atrophy in the irradiated lacrimal gland
1992
Poly(ADP-ribose)polymerase: a perplexing participant in cellular responses to DNA breakage
1991
An analysis of DNA replication in synchronized CHO cells treated with benzo[a]pyrene diol epoxide
1987
Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents
2004
A microRNA component of the p53 tumour suppressor network
2007 StandoutNature
PDL1 Regulation by p53 via miR-34
2015
p21Waf1is required for cellular senescence but not for cell cycle arrest induced by the HDAC inhibitor sodium butyrate
2010
Identification of Wee1 as a novel therapeutic target for mutant RAS-driven acute leukemia and other malignancies
2014
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
2005 StandoutNature
DNA repair in terminally differentiated cells
2002
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Anticancer activities of histone deacetylase inhibitors
2006 Standout
Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c
2008
Apoptosis-based therapies
2002
Role of poly(ADP-ribose) formation in DNA repair
1992 StandoutNatureNobel
MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
2017 Standout
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
The Peutz-Jegher Gene Product LKB1 Is a Mediator of p53-Dependent Cell Death
2001
Principles and practice of DNA filter elution
1991 StandoutNobel
γH2AX and cancer
2008
Dynamics and mechanism of repair of ultraviolet-induced (6–4) photoproduct by photolyase
2010 StandoutNatureNobel
Mitochondrial Regulation of Caspase Activation by Cytochrome Oxidase and Tetramethylphenylenediamine via Cytosolic Cytochrome c Redox State
2007
Genomic Analysis Reveals a Potential Role for Cell Cycle Perturbation in HCV-Mediated Apoptosis of Cultured Hepatocytes
2009 StandoutNobel
The role of senescent cells in ageing
2014 StandoutNature
The Hallmarks of Aging
2013 Standout
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
2006 Standout
A regimen combining the Wee1 inhibitor AZD1775 with HDAC inhibitors targets human acute myeloid leukemia cells harboring various genetic mutations
2014
The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis: Figure 1
2004
A marker for Stevens–Johnson syndrome
2004 StandoutNature
Role of poly(ADP-ribose) synthetase in inflammation and ischaemia–reperfusion
1998
Molecular and biochemical features of poly (ADP-ribose) metabolism
1993
Mitochondria and cell death: outer membrane permeabilization and beyond
2010 Standout
Acid Sphingomyelinase–Deficient Human Lymphoblasts and Mice Are Defective in Radiation-Induced Apoptosis
1996
Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
2006 StandoutNature
PH stepwise alkaline elution of DNA replication intermediates during S phase
1981
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Interleukin -10and Related Cytokines and Receptors
2004
Checkpoints: Controls That Ensure the Order of Cell Cycle Events
1989 StandoutScienceNobel
Xeroderma pigmentosum cells with normal levels of excision repair have a defect in DNA synthesis after UV-irradiation.
1975
Molecular Cloning of the Human XRCC1 Gene, Which Corrects Defective DNA Strand Break Repair and Sister Chromatid Exchange
1990
Repair by human cell extracts of single (6-4) and cyclobutane thymine-thymine photoproducts in DNA.
1993
Free radical mechanisms in neocarzinostatin-induced DNA damage
1987
DNA?protein crosslinks: their induction, repair, and biological consequences
2005
Characterization of the effects induced on DNA in mouse and hamster cells by lithocholic acid.
1987
Substrate and Temperature Dependence of DNA Photolyase Repair Activity Examined with Ultrafast Spectroscopy
1997 StandoutNobel
Therapeutic enzyme deimmunization by combinatorial T-cell epitope removal using neutral drift
2011
Different drugs arrest cells at a number of distinct stages in G2
1975 Nature
Cyclic AMP levels and types I and II cyclic AMP-dependent protein kinase activity in synchronized cells and in quiescent cultures stimulated to proliferate
1978
Quality Control by DNA Repair
1999 StandoutScienceNobel
Calicheamicin γ 1 I : an Antitumor Antibiotic That Cleaves Double-Stranded DNA Site Specifically
1988 StandoutScience
DNA single-strand breaks during repair of UV damage in human fibroblasts and abnormalities of repair in xeroderma pigmentosum.
1976 StandoutNobel
T cells from baxalpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53.
1996
Biological and biochemical consequences of the human ERCC-1 repair gene after transfection into a repair-deficient CHO cell line
1987
The uvrB gene of Escherichia coli has both lexA-repressed and lexA-independent promoters
1982 StandoutNobel
Isolation of Chinese hamster ovary cell mutants deficient in excision repair and mitomycin C bioactivation.
1989
Requirement for p53 and p21 to Sustain G 2 Arrest After DNA Damage
1998 StandoutScience
The RAD9 Gene Controls the Cell Cycle Response to DNA Damage in Saccharomyces cerevisiae
1988 StandoutScienceNobel
Induction of wild-type p53 activity in human cancer cells by ribozymes that repair mutant p53 transcripts
2000
F16, a Mitochondriotoxic Compound, Triggers Apoptosis or Necrosis Depending on the Genetic Background of the Target Carcinoma Cell
2004
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Control of skin cancer by the circadian rhythm
2011 StandoutNobel
Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange.
1990
Formation and removal of DNA cross-links induced by melphalan and nitrogen mustard in relation to drug-induced cytotoxicity in human melanoma cells.
1987
Localization of Inhibition of replicon initiation to damaged regions of DNA
1977
Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis
2000 StandoutScience
Taxane-induced apoptosis decompresses blood vessels and lowers interstitial fluid pressure in solid tumors: clinical implications.
1999
Gene- and strand-specific repair in vitro: partial purification of a transcription-repair coupling factor.
1991 StandoutNobel
Steps in DNA Chain Elongation and Joining after Ultra-violet Irradiation of Human Cells
1972
Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy
2005 StandoutScience
THE BIOLOGY OF THE (6–4) PHOTOPRODUCT
1989
Impact of Protein Kinase PKR in Cell Biology: from Antiviral to Antiproliferative Action
2006
Sequences of the recA gene and protein.
1980 StandoutNobel
Rejoining Kinetics of DNA Single- and Double-Strand Breaks in Normal and DNA Ligase-Deficient Cells after Exposure to Ultraviolet C and Gamma Radiation: An Evaluation of Ligating Activities Involved in Different DNA Repair Processes
1999
Mechanisms of tolerance to DNA lesions in mammalian cells
1981
The formation, identification, and significance of DNA-protein cross-links in mammalian cells.
1987
Physical map of the recA gene.
1979 StandoutNobel
Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants
2003 StandoutScience
Development of Apoptosis and Polyploidy in Human Lymphoblast Cells as a Function of Position in the Cell Cycle at the Time of Irradiation
1996
THE RELATIVE CYTOTOXICITY OF(6–4) PHOTOPRODUCTS AND CYCLOBUTANE DIMERS IN MAMMALIAN CELLS*
1988
Phytosphingosine in combination with ionizing radiation enhances apoptotic cell death in radiation-resistant cancer cells through ROS-dependent and -independent AIF release
2004
Removal of oxygen free-radical-induced 5′,8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cells
2000 StandoutNobel
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Rapid enhancement of protein phosphorylation in A-431 cell membrane preparations by epidermal growth factor.
1979 StandoutNobel
Repair of DNA–polypeptide crosslinks by human excision nuclease
2006 StandoutNobel
Molecular cloning of the human nucleotide-excision-repair gene ERCC4.
1994 StandoutNobel
Evidence for Cardiomyocyte Renewal in Humans
2009 StandoutScience
TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB
1996 StandoutScience
Works of Raymond E. Meyn being referenced
MK-1775, a Novel Wee1 Kinase Inhibitor, Radiosensitizes p53-Defective Human Tumor Cells
2011
TP53 Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence
2011
Therapeutic Delivery of miR-200c Enhances Radiosensitivity in Lung Cancer
2014
The recovery of normal DNA replication kinetics in ultraviolet-irradiated Chinese hamster cells
1977
Hydrogen peroxide insult in cultured mammalian cells: relationships between DNA single-strand breakage, poly(ADP-ribose) metabolism and cell killing
1989
Inhibition of human lung cancer growth following adenovirus-mediated mda-7 gene expression in vivo
2002
Radiation-induced apoptosis: Relevance to radiotherapy
1995
Kinetics of mitotic arrest and apoptosis in murine mammary and ovarian tumors treated with taxol
1995
Analysis of redox regulation of cytochrome c-induced apoptosis in a cell-free system
1999
Astro research fellowship: Apoptosis as a predictor of tumor response to radiation in Stage IB cervical carcinoma
1995
MDA-7 negatively regulates the β-catenin and PI3K signaling pathways in breast and lung tumor cells
2003
L-asparaginase kills lymphoma cells by apoptosis
1993
TRAIL (APO-2L) induces apoptosis in human prostate cancer cells that is inhibitable by Bcl-2
2001
GSH depletion enhances adenoviral bax-induced apoptosis in lung cancer cells
2004
Identification of Cell Cycle Regulatory Genes as Principal Targets of p53-mediated Transcriptional Repression
2006
Implications of apoptotic cell death regulation in cancer therapy
1995
Neocarzinostatin-mediated DNA damage and repair in wild-type and repair-deficient Chinese hamster ovary cells.
1984
Deoxyribonucleic Acid Synthesis in Ultraviolet-Light-Irradiated Chinese Hamster Cells
1971
Induction and Rejoining of γ-Ray-Induced DNA Single- and Double-Strand Breaks in Chinese Hamster AA8 Cells and in Two Radiosensitive Clones
1988
The Induction of DNA-Protein Crosslinks in Hypoxic Cells and Their Possible Contribution to Cell Lethality
1987
Up-regulation of the proapoptotic mediators Bax and Bak after adenovirus-mediated p53 gene transfer in lung cancer cells.
2000
Differential repair of gamma-ray-induced DNA strand breaks by various cellular subpopulations of mouse jejunal epithelium and bone marrow in vivo.
1987
Cell cycle-dependent cytotoxicity of alkylating agents: determination of nitrogen mustard-induced DNA cross-links and their repair in Chinese hamster ovary cells synchronized by centrifugal elutriation.
1986
Histone Deacetylase Inhibitors Radiosensitize Human Melanoma Cells by Suppressing DNA Repair Activity
2005
Non‐histone protein synthesis during G1 phase and its relation to dna replication
1976
Defective removal of DNA cross-links in a repair-deficient mutant of Chinese hamster cells.
1982
Development of Apoptosis in Irradiated Murine Tumors as a Function of Time and Dose
1993
The Effects of Ionizing Radiation on the Kinetics of DNA Replication in Synchronized Chinese Hamster Ovary Cells
1974
Apoptosis in Irradiated Murine Tumors
1991
Vorinostat, a histone deacetylase inhibitor, enhances the response of human tumor cells to ionizing radiation through prolongation of γ-H2AX foci
2006
p53 tumor suppressor gene therapy for cancer.
1999
Adenovirus-mediated wild-type p53 radiosensitizes human tumor cells by suppressing DNA repair capacity.
2003
THE FATE OF PYRIMIDINE DIMERS IN THE DNA OF ULTRAVIOLET‐IRRADIATED CHINESE HAMSTER CELLS
1974
Effect of 3-aminobenzamide on DNA strand-break rejoining and cytotoxicity in CHO cells treated with hydrogen peroxide
1986