Citation Impact
Citing Papers
Hypoxia Induces Trimethylated H3 Lysine 4 by Inhibition of JARID1A Demethylase
2010
Histone Demethylase RBP2 Promotes Lung Tumorigenesis and Cancer Metastasis
2013
MK-2206, an Allosteric Akt Inhibitor, Enhances Antitumor Efficacy by Standard Chemotherapeutic Agents or Molecular Targeted Drugs In vitro and In vivo
2010 Standout
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
HBP1: a HMG box transcriptional repressor that is targeted by the retinoblastoma family.
1997
Cancer and Altered Metabolism: Potential Importance of Hypoxia-Inducible Factor and 2-Oxoglutarate-Dependent Dioxygenases
2011 StandoutNobel
Retinoblastoma-binding protein 2 (RBP2) is frequently expressed in neuroendocrine tumors and promotes the neoplastic phenotype
2016
AKT Inhibition Relieves Feedback Suppression of Receptor Tyrosine Kinase Expression and Activity
2011
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
1995 StandoutNobel
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
RBP2 Belongs to a Family of Demethylases, Specific for Tri-and Dimethylated Lysine 4 on Histone 3
2007
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth
2007
A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F
1992
Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
2008
Translocation of a specific premessenger ribonucleoprotein particle through the nuclear pore studied with electron microscope tomography
1992
Histone Demethylase RBP2 Is Critical for Breast Cancer Progression and Metastasis
2014
The X-Linked Mental Retardation Gene SMCX/JARID1C Defines a Family of Histone H3 Lysine 4 Demethylases
2007
A Screen for New Trithorax Group Genes Identified little imaginal discs, the Drosophila melanogaster Homologue of Human Retinoblastoma Binding Protein 2
2000
The deficiency of Akt1 is sufficient to suppress tumor development in Pten +/− mice
2006
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
1992 StandoutNobel
A protein with similarity to the human retinoblastoma binding protein 2 acts specifically as a repressor for genes regulated by the b mating type locus in Ustilago maydis
2000
Physical interaction of the retinoblastoma protein with human D cyclins
1993
The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner
1992
Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F
1992 Nature
A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex
1992
Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation
1993 Standout
Enhancement of Memory-Related Long-Term Facilitation by ApAF, a Novel Transcription Factor that Acts Downstream from Both CREB1 and CREB2
2000 StandoutNobel
JmjC-domain-containing proteins and histone demethylation
2006
c-Kit Ligand Mediates Increased Expression of Cytosolic Phospholipase A2, Prostaglandin Endoperoxide Synthase-1, and Hematopoietic Prostaglandin D2 Synthase and Increased IgE-dependent Prostaglandin D2 Generation in Immature Mouse Mast Cells
1995
Aplysia CREB2 represses long-term facilitation: Relief of repression converts transient facilitation into long-term functional and structural change
1995 StandoutNobel
The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein
1991 StandoutNobel
Binding of pRB to the PHD Protein RBP2 Promotes Cellular Differentiation
2005 StandoutNobel
Retinoblastoma protein partners
2001
The effect Akt2 deletion on tumor development in Pten+/− mice
2011
The retinoblastoma protein binds E2F residues required for activation in vivo and TBP bindingin vitro
1993
The cell cycle and the retinoblastoma protein family
1994
Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins
1992
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
2010 Standout
The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex
1995 StandoutNobel
Twin of I-POU: A two amino acid difference in the I-POU homeodomain distinguishes an activator from an inhibitor of transcription
1992
Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product
1991 StandoutNobel
The Retinoblastoma Protein Region Required for Interaction with the E2F Transcription Factor Includes the T/E1A Binding and Carboxy-Terminal Sequences
1992
E2F-1 Functions in Mice to Promote Apoptosis and Suppress Proliferation
1996 StandoutNobel
Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair
1993 StandoutNobel
Amino-terminal domains of c-myc and N-myc proteins mediate binding to the retinoblastoma gene product
1991 Nature
p73 is a human p53-related protein that can induce apoptosis
1997 StandoutNatureNobel
Role of a Novel PH-Kinase Domain Interface in PKB/Akt Regulation: Structural Mechanism for Allosteric Inhibition
2009
The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle
1991
A retinoblastoma-binding protein related to a negative regulator of Ras in yeast
1993 Nature
Foxo1 directly regulates the transcription of recombination-activating genes during B cell development
2008
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
2004 StandoutNatureNobel
AKT/PKB Signaling: Navigating the Network
2017 Standout
Retinoblastoma-binding Protein 2 (Rbp2) Potentiates Nuclear Hormone Receptor-mediated Transcription
2001
Homeodomain-DNA recognition
1994 StandoutNobel
RBP1 induces growth arrest by repression of E2F-dependent transcription
1999
A Novel Gene (PLU-1) Containing Highly Conserved Putative DNA/Chromatin Binding Motifs Is Specifically Up-regulated in Breast Cancer
1999
TGFβ inhibition of Cdk4 synthesis is linked to cell cycle arrest
1993
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
lin-35 and lin-53, Two Genes that Antagonize a C. elegans Ras Pathway, Encode Proteins Similar to Rb and Its Binding Protein RbAp48
1998 StandoutNobel
Cyclin A and the retinoblastoma gene product complex with a common transcription factor
1991 StandoutNatureNobel
Functional interactions of the retinoblastoma protein with mammalian D-type cyclins
1993 Standout
The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest
1994
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase
2018 StandoutNobel
The LDL Receptor Gene: A Mosaic of Exons Shared with Different Proteins
1985 StandoutScienceNobel
Identification of a growth suppression domain within the retinoblastoma gene product.
1992 StandoutNobel
Heterodimerization of the transcription factors E2F-1 and DP-1 is required for binding to the adenovirus E4 (ORF6/7) protein
1994
Differential Specificity for Binding of Retinoblastoma Binding Protein 2 to RB, pl07, and TATA-Binding Protein
1994
Functional importance of complex formation between the retinoblastoma tumor suppressor family and adenovirus E1A proteins as determined by mutational analysis of E1A conserved region 2
1994
Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations.
1992
Multiple members of the E2F transcription factor family are the products of oncogenes.
1995
The heat-shock response in xenopus oocytes is controlled at the translational level
1982 StandoutNobel
Corticotropin and beta-endorphin: construction and analysis of recombinant DNA complementary to mRNA for the common precursor.
1979
Direct Transcriptional Repression by pRB and Its Reversal by Specific Cyclins
1995
The retinoblastoma protein physically associates with the human cdc2 kinase.
1992
Characterization of a common precursor to corticotropin and beta-lipotropin: cell-free synthesis of the precursor and identification of corticotropin peptides in the molecule.
1977
Binding of the von Hippel-Lindau Tumor Suppressor Protein to Elongin B and C
1995 StandoutScienceNobel
The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein.
1995
Protein Domains Governing Interactions Between E2F, the Retinoblastoma Gene Product, and Human Papillomavirus type 16 E7 Protein
1993
In Situ Hybridization to Study the Origin and Fate of Identified Neurons
1983 StandoutScienceNobel
Molecular Cloning of Cellular Genes Encoding Retinoblastoma-Associated Proteins: Identification of a Gene with Properties of the Transcription Factor E2F
1992
A Novel Protein with Similarities to Rb Binding Protein 2 Compensates for Loss of Chk1 Function and Affects Histone Modification in Fission Yeast
2004
A single gene encodes multiple neuropeptides mediating a stereotyped behavior
1983 StandoutNobel
Endoplasmic Reticulum Homeostasis Is Modulated by the Forkhead Transcription Factor FKH-9 During Infection of Caenorhabditis elegans
2018 StandoutNobel
An ATP-Site On-Off Switch That Restricts Phosphatase Accessibility of Akt
2012
Alternative RNA splicing of the murine αA-crystallin gene: Protein-coding information within an intron
1983
The retinoblastoma protein binds to a family of E2F transcription factors.
1993
Physiological roles of PKB/Akt isoforms in development and disease
2007
Binding to DNA and the Retinoblastoma Gene Product Promoted by Complex Formation of Different E2F Family Members
1993 Science
Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F.
1992
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism
2003 StandoutScienceNobel
RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila.
1996
The retinoblastoma protein is phosphorylated on multiple sites by human cdc2.
1991
The Transcription Factor E2F-1 Is a Downstream Target of RB Action
1995 StandoutNobel
A multicomponent complex is involved in the splicing of messenger RNA precursors
1985 StandoutNobel
Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein.
1993
A bipotential neuroendocrine precursor whose choice of cell fate is determined by NGF and glucocorticoids
1986 StandoutNobel
Growth factors from murine sarcoma virus-transformed cells.
1978 Standout
Cells Degrade a Novel Inhibitor of Differentiation with E1A-Like Properties upon Exiting the Cell Cycle
2000 StandoutNobel
Translational regulation of δ-crystallin synthesis during lens development in the chicken embryo
1981
A Novel Rb- and p300-Binding Protein Inhibits Transactivation by MyoD
2000
Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F.
1993
Adenovirus E1a prevents the retinoblastoma gene product from repressing the activity of a cellular transcription factor.
1992
A transcriptional tryst
1991 Nature
The retinoblastoma gene product regulates Sp1-mediated transcription.
1992
Multistage nanoparticle delivery system for deep penetration into tumor tissue
2011 StandoutNobel
Characterization of heterogeneous nuclear RNA-protein complexes in vivo with monoclonal antibodies.
1984
Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7
1998 Nature
Dual mechanisms of repression of E2F1 activity by the retinoblastoma gene product.
1996
Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation.
1993
Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins.
1993
Specific small nuclear RNAs are associated with yeast spliceosomes
1986 StandoutNobel
The Scope of the Direct Proline‐Catalyzed Asymmetric Addition of Ketones to Imines
2004
A family of genes that codes for ELH, a neuropeptide eliciting a stereotyped pattern of behavior in Aplysia
1982 StandoutNobel
Interaction of p107 with Cyclin A Independent of Complex Formation with Viral Oncoproteins
1992 Science
The pattern of expression of chick delta-crystallin genes in lens differentiation and in trans-differentiating cultured tissues.
1983
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.
1994 StandoutNobel
Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner.
1992
Cooperative Interactions Between the Caenorhabditis elegans Homeoproteins UNC-86 and MEC-3
1993 StandoutScienceNobel
Inhibition of E2F-1 Transactivation by Direct Binding of the Retinoblastoma Protein
1993
A genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4.
1993
Interaction Between Human Cyclin A and Adenovirus E1A-Associated p107 Protein
1992 Science
Cyclin A recruits p33cdk2to the cellular transcription factor DRTF1
1992 StandoutNobel
Analysis of p107-associated proteins: p107 associates with a form of E2F that differs from pRB-associated E2F-1
1993
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Independent regions of adenovirus E1A are required for binding to and dissociation of E2F-protein complexes.
1993
Endomembrane PtdIns(3,4,5)P3 activates the PI3K/Akt pathway
2015
A family of unusually spliced biologically active transcripts encoded by a Drosophila clock gene
1987 StandoutNatureNobel
Asymmetric Enamine Catalysis
2007 StandoutNobel
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
Protein domains governing interactions between E2F, the retinoblastoma gene product, and human papillomavirus type 16 E7 protein.
1993
Differential specificity for binding of retinoblastoma binding protein 2 to RB, p107, and TATA-binding protein.
1994
The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit.
1993
E2F: a Link Between the Rb Tumor Suppressor Protein and Viral Oncoproteins
1992 Science
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein.
1993
Adenovirus E1A makes two distinct contacts with the retinoblastoma protein
1992
RBP1 Recruits Both Histone Deacetylase-Dependent and -Independent Repression Activities to Retinoblastoma Family Proteins
1999 StandoutNobel
A binding site for transcription factor E2F is a target for trans activation of murine thymidine kinase by polyomavirus large T antigen and plays an important role in growth regulation of the gene
1993
Synthesis and Characterization of Dextran−Peptide−Methotrexate Conjugates for Tumor Targeting via Mediation by Matrix Metalloproteinase II and Matrix Metalloproteinase IX
2004
Works of Raymond E. Jones being referenced
Discovery of 2,3,5-trisubstituted pyridine derivatives as potent Akt1 and Akt2 dual inhibitors
2005
Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene product
1991 Nature
Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors
2004
Allosteric inhibitors of Akt1 and Akt2: A naphthyridinone with efficacy in an A2780 tumor xenograft model
2008
Allosteric inhibitors of Akt1 and Akt2: Discovery of [1,2,4]triazolo[3,4-f][1,6]naphthyridines with potent and balanced activity
2008
Antibodies Specific for the Human Retinoblastoma Protein Identify a Family of Related Polypeptides
1991
Antibodies specific for the human retinoblastoma protein identify a family of related polypeptides.
1991
Chicken lens crystallin DNA sequences show at least two δ-crystallin genes
1980 Nature
Papillomavirus E7 protein binding to the retinoblastoma protein is not required for viral induction of warts
1993
Characterization and cell-free translation of mouse pituitary tumor messenger RNA which directs the synthesis of a corticotropin precursor
1978
Comparison of two delta-crystallin genes in the chicken.
1980
Specific N-methylations of HPV-16 E7 peptides alter binding to the retinoblastoma suppressor protein.
1992
Characterization of cloned human leukocyte 5-lipoxygenase expressed in mammalian cells.
1988
The Synthesis of a Prodrug of Doxorubicin Designed to Provide Reduced Systemic Toxicity and Greater Target Efficacy
2001
Identification of HPV-16 E7 peptides that are potent antagonists of E7 binding to the retinoblastoma suppressor protein.
1990
Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members
2005
Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors
2005
Mouse pituitary tumor mRNA directed cell-free synthesis of polypeptides that are cross-reactive with adrenocorticotropic hormone antiserum
1977
Immunofluorescent localization of the proteins of nuclear ribonucleoprotein complexes.
1980