Citation Impact
Citing Papers
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
A Modular PIP 2 Binding Site as a Determinant of Capsaicin Receptor Sensitivity
2003 StandoutScienceNobel
The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain
2008 Science
Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli
2011 StandoutNobel
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
2007 StandoutNobel
Gain-of-function Na v 1.8 mutations in painful neuropathy
2012
Role of Tetrodotoxin-Resistant Na+Current Slow Inactivation in Adaptation of Action Potential Firing in Small-Diameter Dorsal Root Ganglion Neurons
2003
PIEZO2 is required for mechanotransduction in human stem cell–derived touch receptors
2014
ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures
2003 StandoutNobel
Inhibition of chemokine expression in rat inflamed paws by systemic use of the antihyperalgesic oxidized ATP
2005
ATP is a mediator of chemosensory transduction in the central nervous system
2005 Nature
Delayed Upregulation of ATP P2X3 Receptors of Trigeminal Sensory Neurons by Calcitonin Gene-Related Peptide
2006
RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction
2011 StandoutNobel
Sense and specificity: a molecular identity for nociceptors
1999 StandoutNobel
P2X receptors in the rat uterine cervix, lumbosacral dorsal root ganglia, and spinal cord during pregnancy
2005
Changes in P2X3 purinoceptors in sensory ganglia of the mouse during embryonic and postnatal development
2004
Selective activation of nociceptors by P2X receptor agonists in normal and inflamed rat skin
2001
The Uroepithelium: Not Just a Passive Barrier
2003
TRPV3 and TRPV4 Mediate Warmth-evoked Currents in Primary Mouse Keratinocytes
2004
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Isolation, characterization and total regioselective synthesis of the novel μO-conotoxin MfVIA from Conus magnificus that targets voltage-gated sodium channels
2012
A Role for the P2X Receptor in Urinary Tract Physiology and in the Pathophysiology of Urinary Dysfunction
2005
Chemosensory properties of murine nasal and cutaneous trigeminal neurons identified by viral tracing
2006
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Many little things: one geneticist's view of complex diseases
2005 StandoutNobel
HSP90 inhibitors alter capsaicin- and ATP-induced currents in rat dorsal root ganglion neurons
2002
TRPV3 in keratinocytes transmits temperature information to sensory neurons via ATP
2009 StandoutNobel
Differential Block of Sensory Neuronal Voltage-Gated Sodium Channels by Lacosamide [(2 R)-2-(Acetylamino)-N-benzyl-3-methoxypropanamide], Lidocaine, and Carbamazepine
2008
Purine-mediated signalling in pain and visceral perception
2001
P2X Purinergic Receptor Antagonist Accelerates SkinBarrier Repair and Prevents Epidermal Hyperplasia Inducedby Skin Barrier Disruption
2002
Changes in P2X3 receptor expression in the trigeminal ganglion following monoarthritis of the temporomandibular joint in rats
2005
Prolonged Kappa Opioid Receptor Phosphorylation Mediated by G-protein Receptor Kinase Underlies Sustained Analgesic Tolerance
2004 StandoutNobel
ThermoTRP channels and beyond: mechanisms of temperature sensation
2003 StandoutNobel
TRPM8 mRNA Is Expressed in a Subset of Cold-Responsive Trigeminal Neurons From Rat
2003
Opposite thermosensor in fruitfly and mouse
2003 StandoutNatureNobel
Calmodulin Regulates Current Density and Frequency-Dependent Inhibition of Sodium Channel Nav1.8 in DRG Neurons
2006
Expression of adenosine triphosphate P2X3 receptors in rat molar pulp and trigeminal ganglia
2002
The pain of antisense: in vivo application of antisense oligonucleotides for functional genomics in pain and analgesia
2003
Purinoceptors as therapeutic targets for lower urinary tract dysfunction
2006
Heterogeneity of P2X Receptors in Sympathetic Neurons: Contribution of Neuronal P2X1 Receptors Revealed Using Knockout Mice
2004
P2X receptor-mediated purinergic sensory pathways to the spinal cord dorsal horn
2004
The NaV1.7 sodium channel: from molecule to man
2012
Endogenous opioid mechanisms partially mediate P2X3/P2X2/3‐related antinociception in rat models of inflammatory and chemogenic pain but not neuropathic pain
2005
Itching for Insight
2009 StandoutNobel
Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain
2004
Cell damage excites nociceptors through release of cytosolic ATP
2002
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
Molecular basis of ancestral vertebrate electroreception
2017 StandoutNatureNobel
P2X receptors in peripheral neurons
2001
The ATP-mediated fast current of rat dorsal root ganglion neurons is a novel effector for GABAB receptor activation
2003
Kinetics of antagonist actions at rat P2X2/3 heteromeric receptors
2002
Purinergic mechanisms contribute to mechanosensory transduction in the rat colorectum
2003
The Suramin Analog 4,4′,4″,4″′-(Carbonylbis(imino-5,1,3-benzenetriylbis (carbonylimino)))tetra-kis-benzenesulfonic Acid (NF110) Potently Blocks P2X3 Receptors: Subtype Selectivity Is Determined by Location of Sulfonic Acid Groups
2006
Effects of A‐317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration
2003
Mechanisms underlying enhanced P2X receptor-mediated responses in the neuropathic pain state
2005
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
2011 StandoutNatureNobel
TNP-ATP, a potent P2X3 receptor antagonist, blocks acetic acid-induced abdominal constriction in mice: comparison with reference analgesics
2002
Evidence for the involvement of endogenous ATP and P2X receptors in TMJ pain
2004
Activation and sensitisation of low and high threshold afferent fibres mediated by P2X receptors in the mouse urinary bladder
2002
Voltage-gated sodium channel modulation by scorpion α-toxins
2006
Enhanced thermal avoidance in mice lacking the ATP receptor P2X3
2005
Cellular Distribution and Functions of P2 Receptor Subtypes in Different Systems
2004
ATP analogues with modified phosphate chains and their selectivity for rat P2X2 and P2X2/3 receptors
2003
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors
2006
The P2Y agonist UTP activates cutaneous afferent fibers
2004
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
Structure of the mechanically activated ion channel Piezo1
2017 StandoutNatureNobel
Distinct neurochemical mechanisms are activated following administration of different P2X receptor agonists into the hindpaw of a rat
2003
Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures
2007 Nature
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
Molecular basis of infrared detection by snakes
2010 StandoutNatureNobel
Mrgprd Enhances Excitability in Specific Populations of Cutaneous Murine Polymodal Nociceptors
2009
Molecular properties of P2X receptors
2006
Kinin receptors in pain and inflammation
2001
P2X receptors as cell-surface ATP sensors in health and disease
2006 Nature
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
2001 StandoutNatureNobel
The TTX‐Resistant Sodium Channel Nav1.8 (SNS/PN3): Expression and Correlation with Membrane Properties in Rat Nociceptive Primary Afferent Neurons
2003
Trigeminal P2X3 receptor expression differs from dorsal root ganglion and is modulated by deep tissue inflammation
2005
Migraine — Current Understanding and Treatment
2002 Standout
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
2002 StandoutNatureNobel
ATP Augments Peptide Release from Rat Sensory Neurons in Culture through Activation of P2Y Receptors
2003
Protein kinase C mediates up‐regulation of tetrodotoxin‐resistant, persistent Na+ current in rat and mouse sensory neurones
2005
P2X purinoceptors and sensory transmission
2006
Molecular physiology of p2x receptors and atp signalling at synapses
2001
A TRP Channel that Senses Cold Stimuli and Menthol
2002 StandoutNobel
TRPV channels as thermosensory receptors in epithelial cells
2005
Pharmacology of P2X channels
2006
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Gating and modulation of presumptive NaV1.9 channels in enteric and spinal sensory neurons
2004
Purinergic component of mechanosensory transduction is increased in a rat model of colitis
2004
Characterization of the primary spinal afferent innervation of the mouse colon using retrograde labelling
2004
Differential chemosensory function and receptor expression of splanchnic and pelvic colonic afferents in mice
2005
Contribution of sensitized P2X receptors in inflamed tissue to the mechanical hypersensitivity revealed by phosphorylated ERK in DRG neurons
2004
Synaptic P2X receptors
2001
P2X2 knockout mice and P2X2/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP
2005
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
Effect of tetramethylpyrazine on acute nociception mediated by signaling of P2X receptor activation in rat
2003
The menthol receptor TRPM8 is the principal detector of environmental cold
2007 StandoutNatureNobel
Localisation of P2Y 1 and P2Y 4 receptors in dorsal root, nodose and trigeminal ganglia of the rat
2003
The Drosophila ortholog of vertebrate TRPA1 regulates thermotaxis
2005 StandoutNobel
Peripheral P2X receptors and nociception: interactions with biogenic amine systems
2004
Subunit‐specific P2X‐receptor expression defines chemosensory properties of trigeminal neurons
2004
Analgesic profile of intrathecal P2X3 antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats
2002
Contributions of P2X3 homomeric and heteromeric channels to acute and chronic pain
2003
Methyllycaconitine, α‐bungarotoxin and (+)‐tubocurarine block fast ATP‐gated currents in rat dorsal root ganglion cells
2004
A role for Piezo2 in EPAC1-dependent mechanical allodynia
2013
TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents
2006 StandoutNobel
International Union of Pharmacology. XLVII. Nomenclature and Structure-Function Relationships of Voltage-Gated Sodium Channels
2005 Standout
ATP and UTP excite sensory neurons and induce CREB phosphorylation through the metabotropic receptor, P2Y2
2002
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
A role for the TTX-resistant sodium channel Nav 1.8 in NGF-induced hyperalgesia, but not neuropathic pain
2001
Independent combinatorial effect of antisense oligonucleotides and RNAi-mediated specific inhibition of the recombinant Rat P2X3 receptor
2003
Warm Temperatures Activate TRPV4 in Mouse 308 Keratinocytes
2003
Modulation of sodium currents in rat sensory neurons by nucleotides
2004
Crystal structure of the ATP-gated P2X4 ion channel in the closed state
2009 Nature
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
Alteration of dorsal root ganglion P2X 3 receptor expression and function following spinal nerve ligation in the rat
2002
The neurobiology of itch
2006
Endogenous ATP Involvement in Mustard-Oil-Induced Central Sensitization in Trigeminal Subnucleus Caudalis (Medullary Dorsal Horn)
2005
siRNA relieves chronic neuropathic pain
2004
Functional Downregulation of P2X3Receptor Subunit in Rat Sensory Neurons Reveals a Significant Role in Chronic Neuropathic and Inflammatory Pain
2002
Role of Nitric Oxide in the Control of Cardiac Oxygen Consumption in B2-Kinin Receptor Knockout Mice
1999
Acid potentiation of the capsaicin receptor determined by a key extracellular site
2000 StandoutNobel
Functional properties and toxin pharmacology of a dorsal root ganglion sodium channel viewed through its voltage sensors
2011
VGLUT2 expression in primary afferent neurons is essential for normal acute pain and injury-induced heat hypersensitivity
2010
Vasoactive Potential of the B1Bradykinin Receptor in Normotension and Hypertension
2001
Peripheral Inflammation Sensitizes P2X Receptor-Mediated Responses in Rat Dorsal Root Ganglion Neurons
2002
Therapeutic implications of central and peripheral neurologic mechanisms in migraine
2003
Molecular Physiology of P2X Receptors
2002 Standout
Distinct Roles of P2X Receptors in Modulating Glutamate Release at Different Primary Sensory Synapses in Rat Spinal Cord
2003
Diabetic nephropathy is markedly enhanced in mice lacking the bradykinin B2 receptor
2004 StandoutNobel
ATP Induces Sustained Facilitation of Craniofacial Nociception Through p2x Receptors on Neck Muscle Nociceptors in Mice
2006
Sodium Channels in Normal and Pathological Pain
2010
Pungent products from garlic activate the sensory ion channel TRPA1
2005 StandoutNobel
Decreased renal NO excretion and reduced glomerular tuft area in mice lacking the bradykinin B2receptor
2003
Neuropathic Pain Develops Normally in Mice Lacking both Nav1.7 and Nav1.8
2005
International Union of Pharmacology. XXIV. Current Status of the Nomenclature and Properties of P2X Receptors and Their Subunits
2001
Purinergic control of neuropathic pain
2006
G Protein-Coupled Receptors: Functional and Mechanistic Insights Through Altered Gene Expression
1998 StandoutNobel
Activation of Central Terminal Vanilloid Receptor-1 Receptors and αβ-Methylene-ATP-Sensitive P2X Receptors Reveals a Converged Synaptic Activity onto the Deep Dorsal Horn Neurons of the Spinal Cord
2002
Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain
2004
Impaired Thermosensation in Mice Lacking TRPV3, a Heat and Camphor Sensor in the Skin
2005 StandoutScienceNobel
International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits.
2001
Microelectrode Biosensor for Real-Time Measurement of ATP in Biological Tissue
2005
P2X Receptors in Trigeminal Subnucleus Caudalis Modulate Central Sensitization in Trigeminal Subnucleus Oralis
2002
Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4
2009 StandoutNobel
Role of tissue kallikrein in the cardioprotective effects of ischemic and pharmacological preconditioning in myocardial ischemia
2005
TRP ION CHANNELS AND TEMPERATURE SENSATION
2006 StandoutNobel
Inflammatory mediators and modulators of pain
2006
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury
2007 StandoutNobel
Potentiation of capsaicin receptor activity by metabotropic ATP receptors as a possible mechanism for ATP-evoked pain and hyperalgesia
2001
A Heat-Sensitive TRP Channel Expressed in Keratinocytes
2002 StandoutScienceNobel
Are Voltage-Gated Sodium Channels on the Dorsal Root Ganglion Involved in the Development of Neuropathic Pain?
2011
Neuronal Plasticity: Increasing the Gain in Pain
2000 StandoutScience
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release
2017 StandoutNobel
Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype
2011 StandoutNobel
P2Y‐mediated Ca 2+ response is spatiotemporally graded and synchronized in sensory neurons: a two‐photon photolysis study
2004
P2X Receptors and Nociception
2001
Works of Ray Hill being referenced
Targeted Disruption of a B2 Bradykinin Receptor Gene in Mice Eliminates Bradykinin Action in Smooth Muscle and Neurons
1995
Autoradiography of opioid and ORL1 ligands in opioid receptor triple knockout mice
2002
The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways
1999
NK1 (substance P) receptor antagonists – why are they not analgesic in humans?
2000
Development and characterisation of human 5-HT1B- or 5-HT1D-receptor specific antibodies as unique research tools
1998
Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors
2000 Nature
Basal expression of bradykinin B1 receptor in peripheral sensory ganglia in the rat
2000
Colocalization of CGRP with 5‐HT1B/1D receptors and substance P in trigeminal ganglion neurons in rats
2001