Citation Impact
Citing Papers
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
2015 StandoutNobel
CRISPR/Cas9 in Genome Editing and Beyond
2016
Inhibition of CD47 Effectively Targets Pancreatic Cancer Stem Cells via Dual Mechanisms
2015
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
Machine learning predicts new anti-CRISPR proteins
2020 StandoutNobel
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
Hallmarks of cancer stem cell metabolism
2016
Precision cancer mouse models through genome editing with CRISPR-Cas9
2015
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Smarter drugs emerging in pancreatic cancer therapy
2014
Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference
2015
High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
2016 StandoutNature
Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery
2015
Patient-Derived Xenograft Models: An Emerging Platform for Translational Cancer Research
2014 Standout
Precise and Predictable CRISPR Chromosomal Rearrangements Reveal Principles of Cas9-Mediated Nucleotide Insertion
2018
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Expanding the Biologist’s Toolkit with CRISPR-Cas9
2015 StandoutNobel
Genome-Editing Technologies: Principles and Applications
2016
Transforming Growth Factor-β Signaling in Immunity and Cancer
2019 Standout
Chromosomal Abnormalities in Embryonic and Somatic Stem Cells
2015
RNA-based recognition and targeting: sowing the seeds of specificity
2017 StandoutNobel
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
2015 StandoutNature
Applications of the CRISPR–Cas9 system in cancer biology
2015
In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system
2014 Nature
New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer
2018 Standout
Cancer stem cells revisited
2017 Standout
Suppression of Acquired Docetaxel Resistance in Prostate Cancer through Depletion of Notch- and Hedgehog-Dependent Tumor-Initiating Cells
2012
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
2017 StandoutNatureNobel
Colorectal cancer
2019 Standout
Single-Stranded DNA Cleavage by Divergent CRISPR-Cas9 Enzymes
2015 StandoutNobel
Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch
2016 StandoutNobel
TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin
2018
Unraveling the therapeutic potential of the Hedgehog pathway in cancer
2013 Standout
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
Conformational control of DNA target cleavage by CRISPR–Cas9
2015 StandoutNatureNobel
EMT: 2016
2016 Standout
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
A thermostable Cas9 with increased lifetime in human plasma
2017 StandoutNobel
The next generation of CRISPR–Cas technologies and applications
2019
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
TGF-β Tumor Suppression through a Lethal EMT
2016
TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology
2016 Standout
CRISPR-Cas9-induced t(11;19)/MLL-ENL translocations initiate leukemia in human hematopoietic progenitor cells in vivo
2017 StandoutNobel
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
Cancer stem cells: The challenges ahead
2013
Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications
2017 StandoutNobel
MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells
2015
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9
2016 StandoutNobel
Tumor-associated macrophages promote cancer stem cell-like properties via transforming growth factor-beta1-induced epithelial–mesenchymal transition in hepatocellular carcinoma
2014
CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons
2017
Genome-editing revolution: My whirlwind year with CRISPR
2015 StandoutNatureNobel
A prudent path forward for genomic engineering and germline gene modification
2015 StandoutScienceNobel
A Cas9–guide RNA complex preorganized for target DNA recognition
2015 StandoutScienceNobel
CRISPR-Cas9–guided oncogenic chromosomal translocations with conditional fusion protein expression in human mesenchymal cells
2017
Dynamics of CRISPR-Cas9 genome interrogation in living cells
2015 StandoutScienceNobel
Adoptive cell transfer as personalized immunotherapy for human cancer
2015 StandoutScience
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Surface-Enhanced Raman Spectroscopy for Bioanalysis: Reliability and Challenges
2018 Standout
Role of Cripto-1 during Epithelial-to-Mesenchymal Transition in Development and Cancer
2012
Genomic Engineering and the Future of Medicine
2015 StandoutNobel
Rational design of a split-Cas9 enzyme complex
2015 StandoutNobel
Investigating DNA supercoiling in eukaryotic genomes
2017
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Translational Therapeutic Opportunities in Ductal Adenocarcinoma of the Pancreas
2012
Simultaneous precise editing of multiple genes in human cells
2019 StandoutNobel
Engineering of temperature- and light-switchable Cas9 variants
2013 StandoutNobel
Target specificity of the CRISPR‐Cas9 system
2014
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Works of Raúl Torres being referenced
Nodal/Activin Signaling Drives Self-Renewal and Tumorigenicity of Pancreatic Cancer Stem Cells and Provides a Target for Combined Drug Therapy
2011
Efficient Recreation of t(11;22) EWSR1-FLI1+ in Human Stem Cells Using CRISPR/Cas9
2017
Physical Proximity of Sister Chromatids Promotes Top2-Dependent Intertwining
2016
Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy
2013
Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR–Cas9 system
2014
Nodal/Activin Signaling Drives Self-Renewal and Tumorigenicity of Pancreatic Cancer Stem Cells and Provides a Target for Combined Drug Therapy
2012