Citation Impact
Citing Papers
Pathophysiology of Migraine: A Disorder of Sensory Processing
2017 Standout
Copper-free click chemistry in living animals
2010 StandoutNobel
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
2005 StandoutScience
Fat Metabolism Links Germline Stem Cells and Longevity in C. elegans
2008 StandoutScienceNobel
WGCNA: an R package for weighted correlation network analysis
2008 Standout
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
2009 StandoutNature
Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death
2006
Ceramides as modulators of cellular and whole-body metabolism
2011
Ceramides in insulin resistance and lipotoxicity
2005
A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility
2008
Dipeptidyl peptidase IV inhibitors: A promising new therapeutic approach for the management of type 2 diabetes
2005
GLP‐1 receptor agonists are growth and differentiation factors for pancreatic islet beta cells
2003
Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome
2006
Role of malonyl-CoA in heart disease and the hypothalamic control of obesity
2006
Inflammation and metabolic disorders
2006 StandoutNature
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome
2015 StandoutNature
Dynamics of fat cell turnover in humans
2008 StandoutNature
Minireview: Glucagon-Like Peptides Regulate Cell Proliferation and Apoptosis in the Pancreas, Gut, and Central Nervous System
2004
Radiochemical Malonyl-CoA Decarboxylase Assay: Activity and Subcellular Distribution in Heart and Skeletal Muscle
2002
Signal Transduction by the JNK Group of MAP Kinases
2000 Standout
Genetically Altered Expression of Spermidine/Spermine N1-Acetyltransferase Affects Fat Metabolism in Mice via Acetyl-CoA
2006
Mechanisms linking obesity with cardiovascular disease
2006 StandoutNature
Mitochondrial function in normal and diabetic β-cells
2001 Nature
Assay of the Concentration and 13C-Isotopic Enrichment of Malonyl–Coenzyme A by Gas Chromatography–Mass Spectrometry
2001
Role of exosomes in sperm maturation during the transit along the male reproductive tract
2005
Imaging the Glycosylation State of Cell Surface Glycoproteins by Two‐Photon Fluorescence Lifetime Imaging Microscopy
2013 StandoutNobel
AMPK alterations in cardiac physiology and pathology: enemy or ally?
2006
Autophagy regulates lipid metabolism
2009 StandoutNature
The metabolic syndrome
2010 Standout
Lipotoxicity: when tissues overeat
2003
Cell signalling of the GLP-1 action in rat liver
2003
Glycosylation in Cellular Mechanisms of Health and Disease
2006 Standout
Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans
2004
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Role of diet and fuel overabundance in the development and progression of heart failure
2008
Targeting malonyl CoA inhibition of mitochondrial fatty acid uptake as an approach to treat cardiac ischemia/reperfusion
2009
The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes
2000
The adolescent brain and age-related behavioral manifestations
2000 Standout
Epigallocatechin-gallate (EGCG) regulates autophagy in human retinal pigment epithelial cells: A potential role for reducing UVB light-induced retinal damage
2013
Insulin antagonizes AMP‐activated protein kinase activation by ischemia or anoxia in rat hearts, without affecting total adenine nucleotides
2001
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
Role of the Microbiota in Immunity and Inflammation
2014 Standout
Glucagon-like peptide-1 receptor is involved in learning and neuroprotection
2003
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
2014 StandoutNature
A central role for JNK in obesity and insulin resistance
2002 StandoutNature
Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes
2008
The role of fatty acid unsaturation in minimizing biophysical changes on the structure and local effects of bilayer membranes
2009
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
Neurodegeneration and Inflammation
2008
Prolonged increase of plasma non-esterified fatty acids fully abolishes the stimulatory effect of 24 hours of moderate hyperglycaemia on insulin sensitivity and pancreatic beta-cell function in obese men
2004
Fatty acid metabolism and insulin secretion in pancreatic beta cells
2003
Myocardial Substrate Metabolism in the Normal and Failing Heart
2005 Standout
The Impact of the Gut Microbiota on Human Health: An Integrative View
2012 Standout
Mechanisms linking obesity to insulin resistance and type 2 diabetes
2006 StandoutNature
Physiological role of AMP-activated protein kinase in the heart: graded activation during exercise
2003
From endoplasmic-reticulum stress to the inflammatory response
2008 StandoutNature
Interleukin-1 beta targeted therapy for type 2 diabetes
2009
Malonyl-CoA Decarboxylase Is Not a Substrate of AMP-Activated Protein Kinase in Rat Fast-Twitch Skeletal Muscle or an Islet Cell Line
2001
Glucagon-like peptide-1 prevents beta cell glucolipotoxicity
2004
Balanced pan-PPAR activator bezafibrate in combination with statin: comprehensive lipids control and diabetes prevention?
2012
GLP‐1 derivative liraglutide in rats with β‐cell deficiencies: influence of metabolic state on β‐cell mass dynamics
2003
Leptin and the adrenal gland
2000
PTEN Deletion and Concomitant c-Myc Activation Do Not Lead to Tumor Formation in Pancreatic β Cells
2008 StandoutNobel
Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice
2002
The Physiology of Glucagon-like Peptide 1
2007 Standout
Myocardial Reperfusion Injury
2007 Standout
AMP-activated Protein Kinase Is Required for the Lipid-lowering Effect of Metformin in Insulin-resistant Human HepG2 Cells
2004
Effect of GLP-1 on glucose transport and its cell signalling in human myocytes
2004
The Inflammasomes
2010 Standout
Hyperglycemia and Inhibition of Glycogen Synthase in Streptozotocin-treated Mice
2004
Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure
2013
A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
2002 StandoutNobel
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Decreased fatty acid esterification compensates for the reduced lipolytic activity in hormone-sensitive lipase-deficient white adipose tissue
2003
A Role for Peroxisome Proliferator-activated Receptor α (PPARα) in the Control of Cardiac Malonyl-CoA Levels
2002
Long-chain fatty acid uptake and FAT/CD36 translocation in heart and skeletal muscle
2005
Small Nucleolar RNAs U32a, U33, and U35a Are Critical Mediators of Metabolic Stress
2011
Lipolysis: pathway under construction
2005
The malonyl CoA axis as a potential target for treating ischaemic heart disease
2008
The intrinsic circadian clock within the cardiomyocyte
2005
Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1
2000 Nature
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Incretins, insulin secretion and Type 2 diabetes mellitus
2004
Dietary and Genetic Control of Glucose Transporter 2 Glycosylation Promotes Insulin Secretion in Suppressing Diabetes
2005
Multiple Functions of Jab1 Are Required for Early Embryonic Development and Growth Potential in Mice
2004 StandoutNobel
The endocrine pancreas in non‐diabetic rats after short‐term and long‐term treatment with the long‐acting GLP‐1 derivative NN2211
2003
GLP-1 receptor activation improves β cell function and survival following induction of endoplasmic reticulum stress
2006
Genetic Regulation of Metabolic Pathways in β-Cells Disrupted by Hyperglycemia
2002
Absence of Malonyl Coenzyme A Decarboxylase in Mice Increases Cardiac Glucose Oxidation and Protects the Heart From Ischemic Injury
2006
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity
2022 StandoutNobel
Persistent Improvement of Type 2 Diabetes in the Goto-Kakizaki Rat Model by Expansion of the β-Cell Mass During the Prediabetic Period With Glucagon-Like Peptide-1 or Exendin-4
2002
Relative importance of malonyl CoA and carnitine in maturation of fatty acid oxidation in newborn rabbit heart
2003
The adipoinsular axis: effects of leptin on pancreatic β-cells
2000
Glucagon-like peptide 1 stimulates insulin gene promoter activity by protein kinase A-independent activation of the rat insulin I gene cAMP response element.
2000
Selective Modification of Pyruvate Dehydrogenase Kinase Isoform Expression in Rat Pancreatic Islets Elicited by Starvation and Activation of Peroxisome Proliferator–Activated Receptor-α
2001
Nanoscale distribution of mitochondrial import receptor Tom20 is adjusted to cellular conditions and exhibits an inner-cellular gradient
2011 StandoutNobel
Spatial, temporal and subcellular localization of islet‐brain 1 (IB1), a homologue of JIP‐1, in mouse brain
2000
Myocardial Fatty Acid Metabolism in Health and Disease
2010 Standout
Uncoupling Protein 2 Knockout Mice Have Enhanced Insulin Secretory Capacity After a High-Fat Diet
2002
Coordinate Regulation of Malonyl-CoA Decarboxylase,sn-Glycerol-3-phosphate Acyltransferase, and Acetyl-CoA Carboxylase by AMP-activated Protein Kinase in Rat Tissues in Response to Exercise
2002
Physiological Increase in Plasma Leptin Markedly Inhibits Insulin Secretion In Vivo
2001
Leptin Signaling in the Central Nervous System and the Periphery
2004
Increased Uncoupling Protein-2 Levels in β-cells Are Associated With Impaired Glucose-Stimulated Insulin Secretion
2001
Incretin hormones - an update
2001
Is Oxidative Stress the Pathogenic Mechanism Underlying Insulin Resistance, Diabetes, and Cardiovascular Disease? The Common Soil Hypothesis Revisited
2004
Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets
2003
JNK1 and IKKβ: molecular links between obesity and metabolic dysfunction
2010
Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas.
2000
Malonyl‐CoA decarboxylase (MCD) is differentially regulated in subcellular compartments by 5′AMP‐activated protein kinase (AMPK)
2004
Peroxisomal-proliferator-activated receptor alpha activates transcription of the rat hepatic malonyl-CoA decarboxylase gene: a key regulation of malonyl-CoA level
2004
Characterization of rat liver malonyl-CoA decarboxylase and the study of its role in regulating fatty acid metabolism
2000
Spermidine in health and disease
2018 StandoutScience
Probing the link between citrate and malonyl-CoA in perfused rat hearts
2002
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Islet Inflammation in Type 2 Diabetes
2008
Mitochondrial Dysfunction and Type 2 Diabetes
2005 StandoutScience
Inflammatory Mechanisms in Obesity
2011 Standout
Micromanaging insulin secretion
2004 StandoutNobel
Pancreatic β-Cell Lipotoxicity Induced by Overexpression of Hormone-Sensitive Lipase
2003
Adaptation and Maladaptation of the Heart in Diabetes: Part II
2002
Regulation of cardiac and skeletal muscle malonyl-CoA decarboxylase by fatty acids
2001
Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase
2004 StandoutScience
β-Cell Mitochondria Exhibit Membrane Potential Heterogeneity That Can Be Altered by Stimulatory or Toxic Fuel Levels
2007
Host-Gut Microbiota Metabolic Interactions
2012 StandoutScience
Malonyl CoA Control of Fatty Acid Oxidation in the Ischemic Heart
2002
Selective Deletion of Pten in Pancreatic β Cells Leads to Increased Islet Mass and Resistance to STZ-Induced Diabetes
2006
Improving function and survival of pancreatic islets by endogenous production of glucagon-like peptide 1 (GLP-1)
2006
Neonatal Exendin-4 Prevents the Development of Diabetes in the Intrauterine Growth Retarded Rat
2003
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa
2015 StandoutNobel
Leptin Effects on Pancreatic β-Cell Gene Expression and Function
2004
Glucagon-like Peptide 1 Can Directly Protect the Heart Against Ischemia/Reperfusion Injury
2005
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Insulinotropic Hormone Glucagon-Like Peptide 1 (GLP-1) Activation of Insulin Gene Promoter Inhibited by p38 Mitogen-Activated Protein Kinase*
2001
Glyco-seek: Ultrasensitive Detection of Protein-Specific Glycosylation by Proximity Ligation Polymerase Chain Reaction
2016 StandoutNobel
Proglucagon-Derived Peptides: Mechanisms of Action and Therapeutic Potential
2005
Works of Raphaël Roduit being referenced
Dexamethasone Induces Posttranslational Degradation of GLUT2 and Inhibition of Insulin Secretion in Isolated Pancreatic β Cells
1997
Inhibition of glucose‐induced insulin secretion by long‐term preexposure of pancreatic islets to leptin
1997
Malonyl‐CoA decarboxylase is present in the cytosolic, mitochondrial and peroxisomal compartments of rat hepatocytes
2005
Glucose Down-regulates the Expression of the Peroxisome Proliferator-activated Receptor-α Gene in the Pancreatic β-Cell
2000
Circadian regulation of islet genes involved in insulin production and secretion
2004
Activation of Malonyl-CoA Decarboxylase in Rat Skeletal Muscle by Contraction and the AMP-activated Protein Kinase Activator 5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside
2000
MAP kinase pathways in UV-induced apoptosis of retinal pigment epithelium ARPE19 cells
2008
Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells
1999
The loss of GLUT2 expression in the pancreatic β-cells of diabetic db/db mice is associated with an impaired DNA-binding activity of islet-specific trans-acting factors
1997
A Role for Hormone-Sensitive Lipase in Glucose-Stimulated Insulin Secretion
2001
A Role for the Malonyl-CoA/Long-Chain Acyl-CoA Pathway of Lipid Signaling in the Regulation of Insulin Secretion in Response to Both Fuel and Nonfuel Stimuli
2004
Cloning and expression of rat pancreatic β-cell malonyl-CoA decarboxylase
1999
Saturated Fatty Acids Synergize with Elevated Glucose to Cause Pancreatic β-Cell Death
2003
Malonyl-CoA Signaling, Lipid Partitioning, and Glucolipotoxicity
2002
Glucose and leptin induce apoptosis in human β‐ cells and impair glucose‐stimulated insulin secretion through activation of c‐Jun N‐terminal kinases
2008
Insulin secretion is regulated by the glucose-dependent production of islet β cell macrophage migration inhibitory factor
1997
Leptin Inhibits Directly Glucocorticoid Secretion by Normal Human and Rat Adrenal Gland**This work was supported by a grant from the Swiss National Science Foundation (No. 3100–050748.97/1).
1998
Cloning and expression of rat pancreatic β-cell malonyl-CoA decarboxylase
1999