Standout Papers
Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy
2015 StandoutScience
Selective blockade of inhibitory Fcγ receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells
2005 StandoutNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
Comparison of intravenous infusions of iloprost and oral nifedipine in treatment of Raynaud's phenomenon in patients with systemic sclerosis: a double blind randomised study.
1989
Cytokines and direct cell contact in synovitis: relevance to therapeutic intervention.
1999
Characterization of human blood dendritic cell subsets
2002
Dendritic cells: On the move from bench to bedside
2001
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
T cell receptor signalling in the control of regulatory T cell differentiation and function
2016
IL-10 AS A THERAPEUTIC STRATEGY IN THE TREATMENT OF RHEUMATOID ARTHRITIS
1998
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
1995 StandoutNobel
Terminal differentiation of spontaneous rheumatoid factor–secreting B cells from rheumatoid arthritis patients depends on endogenous interleukin‐1 0
1995
Endothelin-3: selectivity as an anti-aggregatory peptide in vivo
1989 Nobel
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Mucin-1 is expressed on dendritic cells, both in vitro and in vivo
2004
GATA3 controls Foxp3+ regulatory T cell fate during inflammation in mice
2011
DC-SIGN
2000 StandoutNobel
Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood
1996 StandoutNobel
Interleukin‐10 inhibition of the progression of established collagen‐induced arthritis
1996
Steady-state and inflammatory dendritic-cell development
2006
Isolation and Function of Human Dendritic Cells
1994
Increased Plasma Endothelin-1 in Pulmonary Hypertension: Marker or Mediator of Disease?
1991
T-cell anergy
2004
Developmental regulation of MHC class II transport in mouse dendritic cells
1997 StandoutNatureNobel
Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells
2014
FOXP3 and scurfy: how it all began
2014 StandoutNobel
Modulation of the vasodepressor actions of acetylcholine, bradykinin, substance P and endothelin in the rat by a specific inhibitor of nitric oxide formation
1989
The IL-23–IL-17 axis in inflammatory arthritis
2015
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
c‐Rel is crucial for the induction of Foxp3+ regulatory CD4+ T cells but not TH17 cells
2010
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways
2012
Dendritic cells: emerging pharmacological targets of immunosuppressive drugs
2004
Increased vascular contractility in isolated vessels from cigarette smoking rats is mediated by basal endothelin release
2006
Antigen-specific therapeutic approaches for autoimmunity
2019
Distinct mRNA microarray profiles of tolerogenic dendritic cells
2001
Identification of clonogenic common Flt3+M-CSFR+ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow
2007
Prevention and reversal of cartilage degradation in rheumatoid arthritis by interleukin‐10 and interleukin‐4
1996
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Cytokines in cancer pathogenesis and cancer therapy
2004
Tolerogenic dendritic cells generated by RelB silencing using shRNA prevent acute rejection
2012
Regulatory Functions of the Vascular Endothelium
1990 StandoutNobel
Dendritic-cell control of pathogen-driven T-cell polarization
2003
Dendritic Cells In Vivo: A Key Target for a New Vaccine Science
2008 StandoutNobel
Induction of cyclo‐oxygenase‐2 by cytokines in human pulmonary epithelial cells: regulation by dexamethasone
1994 Nobel
Expression of Endothelin-1 in the Lungs of Patients with Pulmonary Hypertension
1993 Standout
Dendritic Cells Ameliorate Autoimmunity in the CNS by Controlling the Homeostasis of PD-1 Receptor+ Regulatory T Cells
2012
Structural and Functional Alteration of Blood Vessels Caused by Cigarette Smoking: An Overview of Molecular Mechanisms
2007
The role of CD40 and CD80 accessory cell molecules in dendritic cell-dependent HIV-1 infection
1994
c‐Rel but not NF‐κB1 is important for T regulatory cell development
2010
Cytokine-secreting tumor cell vaccines
2000
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Fibrinolytic activity of endothelin-3
1989 Nobel
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Dendritic cell immunotherapy: mapping the way
2004
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
2013 StandoutNature
Cancer-related inflammation
2008 StandoutNature
AN INVESTIGATION OF POLYMORPHISM IN THE INTERLEUKIN‐10 GENE PROMOTER
1997
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm
2006 Standout
Cancer immunotherapy with mRNA‐transfected dendritic cells
2004
Putative precursors of endothelin have less vasoconstrictor activity in vitro but a potent pressor effect in vivo
1989
Dendritic Cells and CD4+CD25+ T Regulatory Cells: Crosstalk Between Two Professionals in Immunity versus Tolerance
2006
Role of interleukin‐4 and interleukin‐10 in murine collagen‐induced arthritis. Protective effect of interleukin‐4 and interleukin‐10 treatment on cartilage destruction
1997
Investigation of the relationship between the onset of arthritis and uveitis in genetically predisposed SKG mice
2015 StandoutNobel
The role of interleukin-2 during homeostasis and activation of the immune system
2012
Distribution of Endothelin-like Immunoreactivity and mRNA in the Developing and Adult Human Lung
1991
The Enigmatic Plasmacytoid T Cells Develop into Dendritic Cells with Interleukin (IL)-3 and CD40-Ligand
1997
Identification of dendritic cell colony-forming units among normal human CD34+ bone marrow progenitors that are expanded by c-kit-ligand and yield pure dendritic cell colonies in the presence of granulocyte/macrophage colony-stimulating factor and tumor necrosis factor alpha.
1995
CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha.
1996
Induction of Broad CD4+and CD8+T-Cell Responses and Cross- Neutralizing Antibodies against Hepatitis C Virus by Vaccination with Th1-Adjuvanted Polypeptides Followed by Defective Alphaviral Particles Expressing Envelope Glycoproteins gpE1 and gpE2 and Nonstructural Proteins 3, 4, and 5
2008 StandoutNobel
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Regulatory T Cells: Mechanisms of Differentiation and Function
2007 Standout
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages
1999 StandoutNobel
Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking
1998 StandoutScienceNobel
Dendritic cells with TGF-β1 differentiate naïve CD4+CD25−T cells into islet-protective Foxp3+regulatory T cells
2007 StandoutNobel
CTLA-4 blockade synergizes with tumor-derived granulocyte– macrophage colony-stimulating factor for treatment of an experimental mammary carcinoma
1998 StandoutNobel
Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium.
1993 StandoutNobel
Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice
2016 StandoutNobel
Human blood dendritic cells: binding to vascular endothelium and expression of adhesion molecules
1997
Serum interleukin 10 titers in systemic lupus erythematosus reflect disease activity
1995
Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A
2011 StandoutNobel
IL-12 Acts Selectively on CD8α− Dendritic Cells to Enhance Presentation of a Tumor Peptide In Vivo
1999
The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.
1989 Standout
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
Role of endothelium-derived relaxing factor in regulation of vascular tone and remodeling. Update on humoral regulation of vascular tone.
1991
Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
2005 StandoutNobel
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
2003 StandoutNobel
Regulatory Activity of Autocrine IL-10 on Dendritic Cell Functions
2001
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Antigen capture and major histocompatibility class II compartments of freshly isolated and cultured human blood dendritic cells.
1995
Interleukin-10 and the Interleukin-10 Receptor
2001 Standout
Transport of Peptide-MHC Class II Complexes in Developing Dendritic Cells
2000 StandoutScienceNobel
Strong CD28 costimulation suppresses induction of regulatory T cells from naive precursors through Lck signaling
2011
A Monocyte Conditioned Medium Is More Effective Than Defined Cytokines in Mediating the Terminal Maturation of Human Dendritic Cells
1997
Phenotypic and Functional Maturation of Dendritic Cells Mediated by Heparan Sulfate
2000
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Breast cancer instructs dendritic cells to prime interleukin 13–secreting CD4+ T cells that facilitate tumor development
2007
A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels
1998 StandoutNobel
Dendritic Cells: Unique Leukocyte Populations Which Control the Primary Immune Response
1997
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
Dysbiosis Contributes to Arthritis Development via Activation of Autoreactive T Cells in the Intestine
2016 StandoutNobel
Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature.
1994 StandoutNobel
Mediators produced by the endothelial cell.
1988 Nobel
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
Three populations of cells with dendritic morphology exist in peripheral blood, only one of which is infectable with human immunodeficiency virus type 1.
1995
High TCR Stimuli Prevent Induced Regulatory T Cell Differentiation in a NF-κB–Dependent Manner
2011
IL-12 acts selectively on CD8 alpha- dendritic cells to enhance presentation of a tumor peptide in vivo.
1999
Nod2 Deficiency Augments Th17 Responses and Exacerbates Autoimmune Arthritis
2018 StandoutNobel
Elevated blood pressures in mice lacking endothelial nitric oxide synthase
1996 StandoutNobel
Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.
1994 Standout
Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1
1994 StandoutNobel
CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells.
1996
Works of Ranjeny Thomas being referenced
CD4 + CD25 + regulatory T cells control CD8 + T-cell effector differentiation by modulating IL-2 homeostasis
2011
Antigen-Specific Suppression of Inflammatory Arthritis Using Liposomes
2009
High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis?
2008
Th17 and Th22 cells in psoriatic arthritis and psoriasis
2013
Human peripheral blood dendritic cell subsets. Isolation and characterization of precursor and mature antigen-presenting cells.
1994
Elevated interleukin-10 levels in patients with rheumatoid arthritis
1995
Helminth infections in British troops following an operation in Sierra Leone
2006
Could endogenous self-peptides presented by dendritic cells initiate rheumatoid arthritis?
1996
Immature human monocyte-derived dendritic cells migrate rapidly to draining lymph nodes after intradermal injection for melanoma immunotherapy
1999
Antigen-Specific Suppression of a Primed Immune Response by Dendritic Cells Mediated by Regulatory T Cells Secreting Interleukin-10
2003
Tumor metastasis biopsy as a surrogate marker of response to melanoma immunotherapy
1999
Functional CD40 ligand is expressed by T cells in rheumatoid arthritis.
1997
Differentiated dendritic cells expressing nuclear RelB are predominantly located in rheumatoid synovial tissue perivascular mononuclear cell aggregates
2000
CD40 and Dendritic Cell Function
2003
β‐glucan triggers spondylarthritis and Crohn's disease–like ileitis in SKG mice
2012
CD40 Ligation Conditions Dendritic Cell Antigen-Presenting Function Through Sustained Activation of NF-κB
2002
Functional differentiation of dendritic cells in rheumatoid arthritis: role of CD86 in the synovium.
1996
Steady-state dendritic cells expressing cognate antigen terminate memory CD8+ T-cell responses
2007
c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells
2009
Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.
1988 Nobel
Effector and regulatory T-cell function is differentially regulated by RelB within antigen-presenting cells during GVHD
2007
Nifedipine in the treatment of Raynaud's phenomenon in patients with systemic sclerosis
1987
Rheumatoid synovium is enriched in mature antigen-presenting dendritic cells.
1994
Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients
2015
Proliferation in Monocyte-Derived Dendritic Cell Cultures Is Caused by Progenitor Cells Capable of Myeloid Differentiation
1998
The Colony-Stimulating Factor 1 Receptor Is Expressed on Dendritic Cells during Differentiation and Regulates Their Expansion
2005
Comparative accessory cell function of human peripheral blood dendritic cells and monocytes.
1993
Isolation and characterization of human peripheral blood dendritic cells.
1993
RelB nuclear translocation regulates B cell MHC molecule, CD40 expression, and antigen-presenting cell function
2000
Interleukin‐23 Mediates the Intestinal Response to Microbial β‐1,3‐Glucan and the Development of Spondyloarthritis Pathology in SKG Mice
2014
Nuclear localization of RelB is associated with effective antigen-presenting cell function.
1997
Resistance of Rheumatoid Synovial Dendritic Cells to the Immunosuppressive Effects of IL-10
1999
Dendritic Cells: Origin and Differentiation
1996
Dendritic cells and the pathogenesis of rheumatoid arthritis
1999
ZAP‐70 Genotype Disrupts the Relationship Between Microbiota and Host, Leading to Spondyloarthritis and Ileitis in SKG Mice
2014
Cytokine Expanded Myeloid Precursors Function as Regulatory Antigen-Presenting Cells and Promote Tolerance through IL-10-Producing Regulatory T Cells
2005