Standout Papers
Citation Impact
Citing Papers
Cap‐independent translation: A shared mechanism for lifespan extension by rapamycin, acarbose, and 17α‐estradiol
2021
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
Prolyl Hydroxylases 2 and 3 Act in Gliomas as Protective Negative Feedback Regulators of Hypoxia-Inducible Factors
2009
Cancer and Altered Metabolism: Potential Importance of Hypoxia-Inducible Factor and 2-Oxoglutarate-Dependent Dioxygenases
2011 StandoutNobel
Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR
2014
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
2010 StandoutNobel
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
2009 StandoutNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer
2016 StandoutNobel
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
2016 StandoutNobel
MYC on the Path to Cancer
2012 Standout
Control of Cyclin D1 and Breast Tumorigenesis by the EglN2 Prolyl Hydroxylase
2009 StandoutNobel
Genes that mediate breast cancer metastasis to the brain
2009 StandoutNature
The von Hippel–Lindau tumour suppressor protein: O2 sensing and cancer
2008 StandoutNobel
Overexpression of a DEAD Box Protein (DDX1) in Neuroblastoma and Retinoblastoma Cell Lines
1998
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice
2011 StandoutNobel
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Transcriptional control of differentiation and neurogenesis in autonomic ganglia
2011
First-Line Crizotinib versus Chemotherapy in ALK-Positive Lung Cancer
2014 Standout
Hallmarks of aging: An expanding universe
2023 Standout
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Hypoxia and Inflammation
2011 Standout
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
Platelet factor 4 enhances CD4+ T effector memory cell responses via Akt‐PGC1α‐TFAM signaling‐mediated mitochondrial biogenesis
2020
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
2008 Standout
The 1p36 Tumor Suppressor KIF 1Bβ Is Required for Calcineurin Activation, Controlling Mitochondrial Fission and Apoptosis
2016
The Human Transcription Factors
2018 Standout
Crizotinib inALK-Rearranged Inflammatory Myofibroblastic Tumor
2010 Standout
A germline mutation of the KIF1Bβ gene on 1p36 in a family with neural and nonneural tumors
2008
Prolyl Hydroxylase PHD3 Enhances the Hypoxic Survival and G1 to S Transition of Carcinoma Cells
2011
Germline mutations in TMEM127 confer susceptibility to pheochromocytoma
2010
Sialyltransferases in cancer
2001
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
Genetics and clinical characteristics of hereditary pheochromocytomas and paragangliomas
2011
Treating ALK-positive lung cancer—early successes and future challenges
2012
Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors
2011 StandoutNobel
The role of enhancers in cancer
2016
Strategies to Inhibit Myc and Their Clinical Applicability
2017
A Phase Separation Model for Transcriptional Control
2017
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
2005 StandoutNatureNobel
Lysosomal positioning coordinates cellular nutrient responses
2011
Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression
2012 StandoutNobel
Recent Advances in Neuroblastoma
2010
Mutation analysis of HIF prolyl hydroxylases (PHD/EGLN) in individuals with features of phaeochromocytoma and renal cell carcinoma susceptibility
2010 StandoutNobel
Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers
2019 Standout
CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer
2015
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
2002 Standout
Autophagy and Aging
2011 Standout
Neuroblastoma
2007 Standout
m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer
2020 Standout
18F-FDG Avidity of Pheochromocytomas and Paragangliomas: A New Molecular Imaging Signature?
2009
Anaplastic lymphoma kinase-directed therapy in inflammatory myofibroblastic tumors
2012
Functional Consequences of Succinate Dehydrogenase Mutations
2011
Anaplastic lymphoma kinase as a therapeutic target
2012
New cancer targets emerging from studies of the Von Hippel‐Lindau tumor suppressor protein
2010 StandoutNobel
Prolyl-hydroxylase PHD3 interacts with pyruvate dehydrogenase (PDH)-E1β and regulates the cellular PDH activity
2014
Reading, writing and erasing mRNA methylation
2019 Standout
Emerging novel functions of the oxygen-sensing prolyl hydroxylase domain enzymes
2012
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
A Rap GTPase interactor, RADIL, mediates migration of neural crest precursors
2007
Age at Diagnosis of Pheochromocytoma Differs According to Catecholamine Phenotype and Tumor Location
2010
Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome
2002
Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease
2009
SDH mutations in tumorigenesis and inherited endocrine tumours: lesson from the phaeochromocytoma–paraganglioma syndromes
2009
Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA
2017
Identification of Novel Tumor-Associated Cell Surface Sialoglycoproteins in Human Glioblastoma Tumors Using Quantitative Proteomics
2014
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Cancer stem cells from colorectal cancer-derived cell lines
2010
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
2019 StandoutNobel
A Feedback Loop Involving the Phd3 Prolyl Hydroxylase Tunes the Mammalian Hypoxic Response In Vivo
2009 StandoutNobel
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
FIREWORKS: a bottom-up approach to integrative coessentiality network analysis
2020
Reactivation of Hepatic EPO Synthesis in Mice After PHD Loss
2010 StandoutScienceNobel
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Molecular Biology of Neuroblastoma
1999
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Rare Germline Mutations Identified by Targeted Next-Generation Sequencing of Susceptibility Genes in Pheochromocytoma and Paraganglioma
2014
The International Neuroblastoma Risk Group (INRG) Classification System: An INRG Task Force Report
2008 Standout
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Chemical Glycoproteomics
2016 StandoutNobel
Pheochromocytoma and Paraganglioma: An Endocrine Society Clinical Practice Guideline
2014 Standout
Works of Rani E. George being referenced
Comparison of Primary Neuroblastoma Tumors and Derivative Early-Passage Cell Lines Using Genome-Wide Single Nucleotide Polymorphism Array Analysis
2009
Anaplastic lymphoma kinase: role in cancer pathogenesis and small-molecule inhibitor development for therapy
2009
Genome-Wide Analysis of Neuroblastomas using High-Density Single Nucleotide Polymorphism Arrays
2007
CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer
2014
mRNA circularization by METTL3–eIF3h enhances translation and promotes oncogenesis
2018 Nature
Amplification ofAML1 in childhood acute lymphoblastic leukemias
2001
Zebrafish foxd3 is selectively required for neural crest specification, migration and survival
2006
The kinesin KIF1Bβ acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor
2008 StandoutNobel
Hyperdiploidy Plus Nonamplified MYCN Confers a Favorable Prognosis in Children 12 to 18 Months Old With Disseminated Neuroblastoma: A Pediatric Oncology Group Study
2005
Investigation of co-amplification of the candidate genes ornithine decarboxylase, ribonucleotide reductase, syndecan-1 and a DEAD box gene, DDX1, with N-myc in neuroblastoma. United Kingdom Children's Cancer Study Group.
1996
Tumor-induced sensitivity to apoptosis in T cells from patients with renal cell carcinoma: role of nuclear factor-kappaB suppression.
2001
High-Risk Neuroblastoma Treated With Tandem Autologous Peripheral-Blood Stem Cell–Supported Transplantation: Long-Term Survival Update
2006
Promising Therapeutic Targets in Neuroblastoma
2012