Citation Impact
Citing Papers
p53: puzzle and paradigm.
1996 Standout
The Regulation of AMPK β1, TSC2, and PTEN Expression by p53: Stress, Cell and Tissue Specificity, and the Role of These Gene Products in Modulating the IGF-1-AKT-mTOR Pathways
2007
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
2004 StandoutScience
A novel p53‐inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis‐inducing factor (AIF)
2002
Hallmarks of Cancer: The Next Generation
2011 Standout
Physical Interaction with Human Tumor-derived p53 Mutants Inhibits p63 Activities
2002
The DNA-damage response in human biology and disease
2009 StandoutNature
The Tumor Suppressor Protein p53 Requires a Cofactor to Activate Transcriptionally the Human BAX Promoter
2001
Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain
1997 Standout
Antiproliferative Action of Vitamin D-Related Compounds and Insulin-Like Growth Factor-Binding Protein 5 Accumulation
1997
Mdm2 promotes the rapid degradation of p53
1997 StandoutNature
Signal transduction and transcription factors in rheumatic disease
1999
Inflammation and cancer
2002 StandoutNature
β-Arrestin Is Crucial for Ubiquitination and Down-regulation of the Insulin-like Growth Factor-1 Receptor by Acting as Adaptor for the MDM2 E3 Ligase
2005 StandoutNobel
Regulation of p53 stability by Mdm2
1997 StandoutNature
mTOR Signaling in Growth Control and Disease
2012 Standout
Analyses of p53 Target Genes in the Human Genome by Bioinformatic and Microarray Approaches
2001
Transcriptional repression by p53 involves molecular interactions distinct from those with the TATA box binding protein
1996
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
p53 in growth control and neoplasia
1996
Death Signal-induced Localization of p53 Protein to Mitochondria
2000
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
p53, the Cellular Gatekeeper for Growth and Division
1997 Standout
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
A microRNA component of the p53 tumour suppressor network
2007 StandoutNature
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
p21/CDKN1A Mediates Negative Regulation of Transcription by p53
2003
p53 induction of heparin-binding EGF-like growth factor counteracts p53 growth suppression through activation of MAPK and PI3K/Akt signaling cascades
2001
Strategies for MMP inhibition in cancer: innovations for the post-trial era
2002
The Hallmarks of Cancer
2000 Standout
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Insulin and insulin-like growth factor signalling in neoplasia
2008 Standout
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
2002 StandoutNature
Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system
1993
p53 Negatively Regulates cdc2 Transcription via the CCAAT-binding NF-Y Transcription Factor
1999
The Emergence of Simian/Human Immunodeficiency Viruses
1992
The P53 pathway: what questions remain to be explored?
2006
Angiogenesis in life, disease and medicine
2005 StandoutNature
MX2 is an interferon-induced inhibitor of HIV-1 infection
2013 StandoutNatureNobel
Foundations in Cancer Research p53 and ATM: Cell Cycle, Cell Death, and Cancer
1997
Comparative Binding of p53 to its Promoter and DNA Recognition Elements
2005
Expansion of the eukaryotic proteome by alternative splicing
2010 StandoutNature
Induction of DNA damage, alteration of DNA repair and transcriptional activation by stress hormones
2007
p53 Regulates Insulin-Like Growth Factor-I (IGF-I) Receptor Expression and IGF-I-Induced Tyrosine Phosphorylation in an Osteosarcoma Cell Line: Interaction between p53 and Sp1
1998
p53 in health and disease
2007 Standout
ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase
1997
Live or let die: the cell's response to p53
2002 Standout
HIV as the cause of AIDS
1996 StandoutNobel
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
1999 StandoutNobel
Regulation of the c-met Proto-oncogene Promoter by p53
1999
A model for p53-induced apoptosis
1997 StandoutNature
Molecular mechanisms of cancer development in obesity
2011
Transcriptional activation of tyrosinase and TRP-1 by p53 links UV irradiation to the protective tanning response
2000
Small cell lung cancer: the importance of the extracellular matrix
2004
Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours
1992 StandoutNature
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
1999 StandoutNature
Regulation ofp53downstream genes
1998
Delayed ageing through damage protection by the Arf/p53 pathway
2007 Nature
Wild-Type But Not Mutant p53 Activates the Hepatocyte Growth Factor/Scatter Factor Promoter
1997
The role of senescent cells in ageing
2014 StandoutNature
Role of the Insulin-Like Growth Factor Family in Cancer Development and Progression
2000
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
2019 StandoutNature
The Hallmarks of Aging
2013 Standout
p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling
2008
p53 in signaling checkpoint arrest or apoptosis
1996
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
NF-κB is a target of AKT in anti-apoptotic PDGF signalling
1999 StandoutNature
Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression
2003
Cellular senescence and cancer
1999
Association of p19ARF with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53
1999
p53; from inductive signal to cellular effect
1997
The Bradykinin Type 2 Receptor Is a Target for p53-mediated Transcriptional Activation
2000
Mapping the Encapsidation Determinants of Feline Immunodeficiency Virus
2002
Upregulation of the Elongation Factor-1α Gene by p53 in Association With Death of an Erythroleukemic Cell Line
1997
Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells
2001 StandoutNobel
p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells.
1996
A Mutant p53 That Discriminates between p53-Responsive Genes Cannot Induce Apoptosis
1996
Cellular Actions of the Insulin-Like Growth Factor Binding Proteins
2002
Differential Transactivation by the p53 Transcription Factor Is Highly Dependent on p53 Level and Promoter Target Sequence
2002
Mammalian heterogeneous nuclear ribonucleoprotein A1. Nucleic acid binding properties of the COOH-terminal domain.
1990
Differential Activation of Target Cellular Promoters by p53 Mutants with Impaired Apoptotic Function
1996
p73 Function Is Inhibited by Tumor-Derived p53 Mutants in Mammalian Cells
1999
Regulator of G Protein Signaling Proteins: Novel Multifunctional Drug Targets
2001
Cancer Cell Cycles
1996 StandoutScience
Ku is associated with the telomere in mammals
1999 StandoutNobel
Characterization of Structural p53 Mutants Which Show Selective Defects in Apoptosis but Not Cell Cycle Arrest
1998
Activation and activities of the p53 tumour suppressor protein
2001
The Vif and Gag proteins of human immunodeficiency virus type 1 colocalize in infected human T cells
1997
Death Receptors: Signaling and Modulation
1998 StandoutScience
PTGF-β , a type β transforming growth factor (TGF-β) superfamily member, is a p53 target gene that inhibits tumor cell growth via TGF-β signaling pathway
2000
PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family
2000
Requirement for p53 and p21 to Sustain G 2 Arrest After DNA Damage
1998 StandoutScience
Transcriptional control of human p53-regulated genes
2008 Standout
Genetic diversity of human immunodeficiency virus type 2: evidence for distinct sequence subtypes with differences in virus biology
1994
Effects of Energy Balance on Cancer in Genetically Altered Mice
2004
Cell Surface Trafficking of Fas: A Rapid Mechanism of p53-Mediated Apoptosis
1998 Science
A Subset of Tumor-Derived Mutant Forms of p53 Down-Regulate p63 and p73 through a Direct Interaction with the p53 Core Domain
2001
Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner
1997
Surfing the p53 network
2000 StandoutNature
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro
1992
Inhibitors of human immunodeficiency virus integrase.
1993 StandoutNobel
Vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells
1993
The N-Terminal Domain of p73 Interacts with the CH1 Domain of p300/CREB Binding Protein and Mediates Transcriptional Activation and Apoptosis
2000
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
GTPase-Activating Proteins for Heterotrimeric G Proteins: Regulators of G Protein Signaling (RGS) and RGS-Like Proteins
2000
Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes
1992
The CDK7-cycH-p36 Complex of Transcription Factor IIH Phosphorylates p53, Enhancing Its Sequence-Specific DNA Binding Activity In Vitro
1997
Insulin-like growth factor binding protein 3 mediates retinoic acid- and transforming growth factor beta2-induced growth inhibition in human breast cancer cells.
1996
Caspases: Enemies Within
1998 StandoutScience
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
The IGF axis and programmed cell death
1999
The Role of the IGF System in Cancer Growth and Metastasis: Overview and Recent Insights
2007
Characterization of human immunodeficiency virus type 1 Vif particle incorporation
1996
ei24, a p53 Response Gene Involved in Growth Suppression and Apoptosis
2000
A Matter of Life and Cell Death
1998 Science
Transcriptional Activation of the Human Epidermal Growth Factor Receptor Promoter by Human p53
1996
Works of Randy Talbott being referenced
Induction of the growth inhibitor IGF-binding protein 3 by p53
1995 Nature
PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes
1999
Comparison of two host cell range variants of feline immunodeficiency virus
1990
Gene regulation by temperature-sensitive p53 mutants: identification of p53 response genes.
1994
The p53 tumor suppressor targets a novel regulator of G protein signaling
1997
Mapping the determinants of human immunodeficiency virus 2 for infectivity, replication efficiency, and cytopathicity.
1993
Nucleotide sequence and genomic organization of feline immunodeficiency virus.
1989
Inhibition of angiogenesis and metastasis in two murine models by the matrix metalloproteinase inhibitor, BMS-275291.
2001
A single-stranded nucleic acid binding sequence common to the heterogeneous nuclear ribonucleoparticle protein A1 and murine recombinant virus gp70.
1990