Standout Papers
Citation Impact
Citing Papers
A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression
2005 StandoutNobel
Transcription Units for mRNA Production in Eukaryotic Cells and Their DNA Viruses
1979
Different species of messenger RNA encode receptor and secretory IgM μ chains differing at their carboxy termini
1980 Nature
The methylation of adenovirus-specific nuclear and cytoplasmic RNA
1976
Poly A Sequences at the 3′ Termini of Rabbit Globin mRNAs
1971
Correlation between fragmented immunoglobulin genes and heavy chain deletion mutants
1979 Nature
A putative cell signal encoded by the folded gastrulation gene coordinates cell shape changes during Drosophila gastrulation
1994 StandoutNobel
The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein
1989 Nature
IκB: a Specific Inhibitor of the NF-κB Transcription Factor
1988 StandoutScienceNobel
fringe, a boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development
1994 StandoutNobel
Sequences of the joining region genes for immunoglobulin heavy chains and their role in generation of antibody diversity.
1981
Steps in the processing of Ad2 mRNA: Poly(A)+ Nuclear sequences are conserved and poly(A) addition precedes splicing
1978
Rearrangements of Immunoglobulin Genes during Differentiation and Evolution
1981 StandoutNobel
A Polynucleotide Segment Rich in Adenylic Acid in the Rapidly-Labeled Polyribosomal RNA Component of Mouse Sarcoma 180 Ascites Cells
1971
Structure of human immunoglobulin gamma genes: implications for evolution of a gene family
1982 StandoutNobel
Expression and regulation of immunoglobulin heavy chain gene transfected into lymphoid cells.
1983
A mechanism for RNA splicing.
1980
Somatic generation of antibody diversity.
1976 StandoutNobel
Detection of Polyadenylic Acid Sequences in Viral and Eukaryotic RNA
1972
Linkage of the four gamma subclass heavy chain genes.
1981 StandoutNobel
Solvation energy in protein folding and binding
1986 StandoutNature
Transcripts of the immunoglobulin C mu gene vary in structure and splicing during lymphoid development.
1980
Cloning immunoglobulin gamma 2b chain gene of mouse: characterization and partial sequence determination.
1979 StandoutNobel
Complete primary structures of the E beta chain and gene of the mouse major histocompatibility complex.
1983 StandoutNobel
Multiple Immunoglobulin Heavy-Chain Gene Transcripts in Abelson Murine Leukemia Virus-Transformed Lymphoid Cell Lines
1982 Nobel
Evidence for splicing of interrupted immunoglobulin variable and constant region sequences in nuclear RNA
1978 Nature
Polyadenylic Acid Sequences in the Virion RNA of Poliovirus and Eastern Equine Encephalitis Virus
1972 Science
A mouse immunoglobulin heavy chain deletion mutant: isolation of a cDNA clone and sequence analysis of the mRNA
1980
A κ-immunoglobulin gene is formed by site-specific recombination without further somatic mutation
1979 Nature
In Vitro Synthesis of DNA Complementary to Purified Rabbit Globin mRNA
1972
Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice
2007 StandoutNobel
Complete nucleotide sequence of immunoglobulin γ2b chain gene cloned from newborn mouse DNA
1980 StandoutNatureNobel
Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene.
1979
The complete nucleotide sequence of mouse immunoglobulin γ2a gene and evolution of heavy chain genes: further evidence for intervening sequence-mediated domain transfer
1981 StandoutNobel
Biogenesis and characterization of histone messenger RNA in HeLa cells
1972
Specific transcription and RNA splicing defects in five cloned β-thalassaemia genes
1983 Nature
Cloning and sequence determination of the gene for the human immunoglobulin epsilon chain expressed in a myeloma cell line.
1982 StandoutNobel
Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins
1984 Nature
Molecular cloning of an immunoglobulin kappa constant gene from NZB mouse
1981
Charon Phages: Safer Derivatives of Bacteriophage Lambda for DNA Cloning
1977 StandoutScienceNobel
Amino acid sequence of homogeneous antibodies to dextran and DNA rearrangments in heavy chain V-region gene segments
1980 Nature
Unusual splice sites revealed by mutagenic inactivation of an authentic splice site of the rabbit β-globin gene
1983 Nature
Nucleotide sequences of switch regions of immunoglobulin C epsilon and C gamma genes and their comparison.
1982 StandoutNobel
Genomic organization and sequence of T-cell receptor β-chain constant- and joining-region genes
1984 Nature
Complete nucleotide sequence of mouse imunoglobulin μ gene and comparison with other immunoglobulin heavy chain genes
1980 StandoutNobel
Polyadenylic Acid Sequences in the Heterogeneous Nuclear RNA and Rapidly-Labeled Polyribosomal RNA of HeLa Cells: Possible Evidence for a Precursor Relationship
1971
Adenylyl Cyclase Amino Acid Sequence: Possible Channel- or Transporter-Like Structure
1989 StandoutScienceNobel
The synthesis and processing of the messenger RNAs specifying heavy and light chain immunoglobulins in MPC-11 cells
1978
Generation of long mRNA for membrane immunoglobulin γ2a chains by differential splicing
1981 Nature
Characterization of Productive and Sterile Transcripts from the Immunoglobulin Heavy-Chain Locus: Processing of μm and μs mRNA
1983
Cloning of Human Mineralocorticoid Receptor Complementary DNA: Structural and Functional Kinship with the Glucocorticoid Receptor
1987 StandoutScience
Two mRNAs with different 3′ ends encode membrane-bound and secreted forms of immunoglobulin μ chain
1980
Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism
1986 StandoutNobel
Deletions in the constant region locus can account for switches in immunoglobulin heavy chain expression
1980 Nature
Cloning and complete nucleotide sequence of mouse immunoglobulin γ1 chain gene
1979 StandoutNobel
The role of DNA rearrangement and alternative RNA processing in the expression of immunoglobulin delta genes
1981 StandoutNobel
The nucleotide sequences of rearranged and germline immunoglobulin VH genes of a mouse myeloma MC101 and evolution of VH genes in mouse.
1982 StandoutNobel
An immunoglobulin heavy-chain gene is formed by at least two recombinational events
1980 Nature
Construction of chimaeric processed immunoglobulin genes containing mouse variable and human constant region sequences
1985 StandoutNatureNobel
Structure-Based Design of Functional Amyloid Materials
2014 StandoutNobel
Reconstitution of antigen-specific suppressor activity with translation products of mRNA
1982 StandoutNatureNobel
Nucleotide sequences of gene segments encoding membrane domains of immunoglobulin gamma chains.
1982 StandoutNobel
Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance
1986 Nature
Translation of mouse globin messenger ribonucleic acid from which the poly(adenylic acid) sequence has been removed
1974
DNA Electron Microscopy - Part
1981
Deletions in immunoglobulin mu chains.
1982 StandoutNobel
Comparison of mRNA precursors in plasmacytomas producing closely related κ chains
1979
Are snRNPs involved in splicing?
1980 Nature
Identification and nucleotide sequence of a diversity DNA segment (D) of immunoglobulin heavy-chain genes
1981 StandoutNatureNobel
Structure, organization, and somatic rearrangement of T cell gamma genes
1985
Isolation and Characterization of Adenovirus Messenger Ribonucleic Acid in Productive Infection
1972 Standout
Poly (A) and Poly (U) in Poliovirus Double Stranded RNA
1973
Requirement of 3′-Terminal Poly(adenylic acid) for the Infectivity of Poliovirus RNA
1974 StandoutNobel
Implications of RNA⋅RNA Splicing in Evolution of Eukaryotic Cells
1978 Science
Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes
1980 StandoutNatureNobel
Expression of lymphocyte surface IgE does not require switch recombination
1982 StandoutNatureNobel
Structure and multiplicity of genes for the human immunoglobulin heavy chain variable region.
1980
High Stability of Messenger RNA in Growing Cultured Cells
1972 Nature
Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch.
1980 StandoutNobel
Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments.
1982 StandoutNobel
Isolation of immunoglobulin messenger ribonucleic acid from human lymphoblastoid cell lines
1981
Polyadenylic Acid Segment in mRNA Becomes Shorter with Age
1973
The NMR–Rosetta capsid model of M13 bacteriophage reveals a quadrupled hydrophobic packing epitope
2015 StandoutNobel
Mutant immunoglobulin genes have repetitive DNA elements inserted into their intervening sequences.
1982
5′ Flanking region of immunoglobulin heavy chain constant region genes displays length heterogeneity in germlines of inbred mouse strains
1980
Unusual organization and diversity of T-cell receptor a-chain genes
1985 StandoutNatureNobel
Cmu gene rearrangement of mouse immunoglobulin genes in normal B cells occurs on both the expressed and nonexpressed chromosomes.
1981
An immunoglobulin promoter region is unaltered by DNA rearrangement and somatic mutation during B-cell development
1982
A mutant immunoglobulin light chain is formed by aberrant DNA- and RNA-splicing events
1980 Nature
Molecular cloning of seven mouse immunoglobulin .kappa. chain messenger ribonucleic acids
1980
Polynucleotide sequences in eukaryotic DNA and RNA that form ribonuclease-resistant complexes with polyuridylic acid
1974 StandoutNobel
A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes
1986 NatureNobel
Polyadenylic Acid at the 3′-Terminus of Poliovirus RNA
1972
Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ
1977 StandoutScience
Organization of the constant-region gene family of the mouse immunoglobulin heavy chain
1982 StandoutNobel
A Protein of Molecular Weight 78,000 Bound to the Polyadenylate Region of Eukaryotic Messenger RNAs
1973 StandoutNobel
Deletion of immunoglobulin heavy chain genes from expressed allelic chromosome
1980 StandoutNatureNobel
Polyadenylic acid sequences on 3' termini of vaccinia messenger ribonucleic acid and mammalian nuclear and messenger ribonucleic acid
1972
Immunoglobulin heavy chain gene organization in mice: analysis of a myeloma genomic clone containing variable and alpha constant regions.
1979
Relative occurrence of polyadenylic acid sequences in messenger and heterogeneous nuclear RNA of L cells as determined by poly (U)-hydroxylapatite chromatography
1972
Primary structure of the Fc region of human immunoglobulin D: implications for evolutionary origin and biological function.
1981
Ubiquitous, interspersed repeated sequences in mammalian genomes.
1980
Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA
1989 StandoutScience
mRNA for surface immunoglobulin gamma chains encodes a highly conserved transmembrane sequence and a 28-residue intracellular domain.
1982
Mitochondrial Protein Synthesis: RNA with the Properties of Eukaryotic Messenger RNA
1973
Cloned pairs of variable region genes for immunoglobulin heavy chains isolated from a clone library of the entire mouse genome.
1979
Cloning of human immunoglobulin μ gene and comparison with mouse μ gene
1980 StandoutNobel
Murine myeloma immunoglobulin heavy-chain mRNA. Isolation, partial purification, and characterization of .gamma.1, .gamma.2a, .gamma.2b, .gamma.3, .mu., and .alpha. heavy-chain mRNAs
1979
Three abundance classes in HeLa cell messenger RNA
1974 StandoutNatureNobel
Methylation patterns of immunoglobulin genes in lymphoid cells: correlation of expression and differentiation with undermethylation.
1983
A Particle Associated with the Polyadenylate Segment in Mammalian Messenger RNA
1972
Rearrangement of genetic information may produce immunoglobulin diversity
1978 Nature
Protein-Binding Sites in Ig Gene Enhancers Determine Transcriptional Activity and Inducibility
1987 ScienceNobel
One predominant 5′-undecanucleotide in adenovirus 2 late messenger RNAs
1977 StandoutNobel
Organisation and sequence studies of the 17-piece chicken conalbumin gene
1979 Nature
Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells
1986 Standout
Intervening sequences divide the gene for the constant region of mouse immunoglobulin mu chains into segments, each encoding a domain.
1980
Exon shuffling generates an immunoglobulin heavy chain gene.
1980 StandoutNobel
Transcription of mouse kappa chain genes: implications for allelic exclusion.
1980 StandoutNobel
Evidence that all messenger RNA molecules (except histone messenger RNA) contain poly(A) sequences and that the poly(A) has a nuclear function
1972
Genomic sequencing.
1984 Standout
Duplication and deletion in the human immunoglobulin ϵ genes
1982
Characterization of productive and sterile transcripts from the immunoglobulin heavy-chain locus: processing of micron and muS mRNA.
1983
DNA sequences of the joining regions of mouse lambda light chain immunoglobulin genes.
1982 StandoutNobel
Sequence relationships between adenovirus 2 early RNA and viral RNA size classes synthesized at 18 hours after infection
1975
Dual expression of λ genes in the MOPC-315 plasmacytoma
1981 NatureNobel
Sequence of the Cloned Gene for the Constant Region of Murine γ2b Immunoglobulin Heavy Chain
1979 Science
CH gene rearrangements in IgM-bearing B cells and in the normal splenic DNA component of hybridomas making different isotypes of antibody
1980
RNA splicing mutation in an aberrantly rearranged immunoglobulin lambda I gene.
1981
Rearrangement of immunoglobulin genes
1979
Two mRNAs can be produced from a single immunoglobulin μ gene by alternative RNA processing pathways
1980
RNA of RNA Tumour Viruses contains Poly A
1972
Nucleotide sequence of a cloned cDNA corresponding to secreted μ chain of mouse immunoglobulin
1980
Physical and biological properties of an epsilon-heavy chain mRNA and a kappa-light chain mRNA coding for rat immunoglobulin E.
1981
Contribution of immunoglobulin heavy-chain variable-region genes to antibody diversity
1980 Nature
Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose
1972 Standout
J Genes for Heavy Chain Immunoglobulins of Mouse
1980 Science
Mouse T cell antigen receptor: Structure and organization of constant and joining gene segments encoding the β polypeptide
1984
In vitro Synthesis of DNA Complementary to Rabbit Reticulocyte 10S RNA
1972 StandoutNobel
The regulated expression of β-globin genes introduced into mouse erythroleukemia cells
1983 StandoutNobel
Somatic generation of antibody diversity
1983 StandoutNatureNobel
Evolutionary approach to the question of immunoglobulin heavy chain switching: evidence from cloned human and mouse genes.
1980
The role of gene deletion in the immunoglobulin heavy chain switch
1980 Nature
An immunoglobulin deletion mutant with implications for the heavy-chain switch and RNA splicing
1980 StandoutNatureNobel
Functional immunoglobulin M production after transfection of cloned immunoglobulin heavy and light chain genes into lymphoid cells.
1983 StandoutNobel
Biogenesis of membrane-bound and secreted immunoglobulins: two primary translation products of the human delta chain, differentially N-glycosylated to four discrete forms in vivo and in vitro.
1981 StandoutNobel
Structure of the constant and 3′ untranslated regions of the murine Balb/c γ2a heavy chain messenger RNA
1980
Mouse globin system: a functional and evolutionary analysis
1980 Science
Sequences at the somatic recombination sites of immunoglobulin light-chain genes
1979 StandoutNatureNobel
Cloning Human Fetal γ Globin and Mouse α-Type Globin DNA: Preparation and Screening of Shotgun Collections
1978 StandoutScienceNobel
Adenovirus transcription
1976
Nucleotide sequence divergence of mouse immunoglobulin gamma 1 and gamma 2b chain genes and the hypothesis of intervening sequence-mediated domain transfer.
1980 StandoutNobel
Works of Randolph Wall being referenced
A labile inhibitor blocks immunoglobulin kappa-light-chain-gene transcription in a pre-B leukemic cell line.
1986
The structure of the mouse immunoglobulin in γ3membrane gene segment
1983
Recombinant DNA clones constructed from immunoglobulin kappa light chain messenger RNA
1978
Addition of Polyadenylate Sequences to Virus-Specific RNA during Adenovirus Replication
1971
Gene segments encoding transmembrane carboxyl termini of immunoglobulin γ chains
1981
RNA splicing generates a variant light chain from an aberrantly rearranged κ gene
1980 Nature
A general method for cloning eukaryotic structural gene sequences.
1976
Immunoglobulin light chain mRNA is processed from large nuclear RNA.
1978
Expression of IgD may use both DNA rearrangement and RNA splicing mechanisms
1981
Expression of an immunoglobulin heavy chain gene transfected into lymphocytes.
1984
Presence of Cell and Virus Specific Sequences in the Same Molecules of Nuclear RNA from Virus Transformed Cells
1971
An Adenylic Acid-Rich Sequence in Messenger RNA of HeLa Cells and Its Possible Relationship to Reiterated Sites in DNA
1971
Immunoglobulin heavy chain genes: demethylation accompanies class switching.
1981
Intermolecular duplexes in heterogeneous nuclear RNA from HeLa cells
1977
Analysis of membrane and surface protein sequences with the hydrophobic moment plot
1984 Standout
Processing of adenovirus specific nuclear RNA during virus replication
1972
Variable and constant regions are separated in the 10-kbase transcription unit coding for immunoglobulin kappa light chains.
1978
Polyadenylic Acid Sequences: Role in Conversion of Nuclear RNA into Messenger RNA
1971 Science
Mouse Cμ heavy chain immunoglobulin gene segment contains three intervening sequences separating domains
1980 Nature
Nuclear RNA precursors in the processing pathway to MOPC 21 κ light chain messenger RNA
1979
Domains and the hinge region of an immunoglobulin heavy chain are encoded in separate DNA segments
1979 StandoutNatureNobel
A general method for the large-scale isolation of polysomes and messenger RNA applied to MOPC 21 mouse myeloma tumors
1977
Somatic hypermutation of the B cell receptor genesB29(Igβ, CD79b) andmb1(Igα, CD79a)
2003
Further evidence on the nuclear origin and transfer to the cytoplasm of polyadenylic acid sequences in mammalian cell RNA
1973