Citation Impact
Citing Papers
Molecular Dissection of Formation of Senescence-Associated Heterochromatin Foci
2007
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells
2012 StandoutScience
Osteoclasts promote the formation of hematopoietic stem cell niches in the bone marrow
2012
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells
2009
SIRT3 Reverses Aging-Associated Degeneration
2013
Hallmarks of Cancer: The Next Generation
2011 Standout
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
The DNA-damage response in human biology and disease
2009 StandoutNature
Genome-scale DNA methylation maps of pluripotent and differentiated cells
2008 StandoutNature
The stem cell niches in bone
2006
Wnt Signaling in the Niche Enforces Hematopoietic Stem Cell Quiescence and Is Necessary to Preserve Self-Renewal In Vivo
2008
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
2007
Maintenance of the Hematopoietic Stem Cell Pool by CXCL12-CXCR4 Chemokine Signaling in Bone Marrow Stromal Cell Niches
2006 Standout
Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors
2008 Nature
Telomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice
2008
mTOR Signaling in Growth Control and Disease
2012 Standout
Circular RNAs are a large class of animal RNAs with regulatory potency
2013 StandoutNature
Rb Regulates Interactions between Hematopoietic Stem Cells and Their Bone Marrow Microenvironment
2007
Regulatory Mechanisms of Tumor Suppressor P16INK4Aand Their Relevance to Cancer
2011
Cancer to bone: a fatal attraction
2011 Standout
Epigenetic regulation of aging stem cells
2011
Cellular senescence: when bad things happen to good cells
2007 Standout
The genetics of ageing
2010 StandoutNature
Thrombopoietin/MPL Signaling Regulates Hematopoietic Stem Cell Quiescence and Interaction with the Osteoblastic Niche
2007
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Ionizing radiation‐induced long‐term expression of senescence markers in mice is independent of p53 and immune status
2010
Increased skeletal VEGF enhances β‐catenin activity and results in excessively ossified bones
2009
Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
2014 StandoutNature
Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche
2007 Standout
Mesenchymal stem cells in health and disease
2008 Standout
Cellular Senescence in Cancer and Aging
2007 Standout
Cellular senescence and organismal aging
2008
The bone marrow at the crossroads of blood and immunity
2011
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
Expression of p16INK4a in peripheral blood T‐cells is a biomarker of human aging
2009
The Epigenomics of Cancer
2007 Standout
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche
2008 Nature
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Integrins and bone metastasis: Integrating tumor cell and stromal cell interactions
2010
Rescue of key features of the p63‐null epithelial phenotype by inactivation of Ink4a and Arf
2009
Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells
2008 Nature
ROS Function in Redox Signaling and Oxidative Stress
2014 Standout
Targeting HIF1α Eliminates Cancer Stem Cells in Hematological Malignancies
2011
p16INK4a induces an age-dependent decline in islet regenerative potential
2006 Nature
Expression of Linear and Novel Circular Forms of an INK4/ARF-Associated Non-Coding RNA Correlates with Atherosclerosis Risk
2010
How stem cells age and why this makes us grow old
2007
Forging a signature of in vivo senescence
2015
Bmi1 regulates mitochondrial function and the DNA damage response pathway
2009 Nature
mTOR: from growth signal integration to cancer, diabetes and ageing
2010 Standout
Principles of adoptive T cell cancer therapy
2007
Altered senescence, apoptosis, and DNA damage response in a mutant p53 model of accelerated aging
2009
Uncertainty in the niches that maintain haematopoietic stem cells
2008
Anti‐aging activity of the Ink4/Arf locus
2009
Epigenetics and aging: the targets and the marks
2007
Tumor Suppressor and Aging Biomarker p16INK4a Induces Cellular Senescence without the Associated Inflammatory Secretory Phenotype
2011
A common variant of the p16INK4a genetic region is associated with physical function in older people
2007
Integrating Physiological Regulation with Stem Cell and Tissue Homeostasis
2011
Cellular senescence: putting the paradoxes in perspective
2010
Stems Cells and the Pathways to Aging and Cancer
2008
Senescent Cells: A Novel Therapeutic Target for Aging and Age-Related Diseases
2012
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
2010 StandoutNature
The common biology of cancer and ageing
2007 Nature
Healing and Hurting: Molecular Mechanisms, Functions, and Pathologies of Cellular Senescence
2009
Two faces of p53: aging and tumor suppression
2007
The stem-cell niche as an entity of action
2006 Nature
Emerging models and paradigms for stem cell ageing
2011
Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
2014 StandoutNature
Cancer immunotherapy comes of age
2011 StandoutNature
The molecular signature of therapeutic mesenchymal stem cells exposes the architecture of the hematopoietic stem cell niche synapse
2007
Bone-marrow haematopoietic-stem-cell niches
2006
Systemic Endocrine Instigation of Indolent Tumor Growth Requires Osteopontin
2008
Evidence that senescent human prostate epithelial cells enhance tumorigenicity: Cell fusion as a potential mechanism and inhibition by p16INK4a and hTERT
2007
Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
2009 Nature
Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model
2012
The biology of infertility: research advances and clinical challenges
2008
Correlation between severity and SMN protein level in spinal muscular atrophy
1997 Standout
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
Delayed ageing through damage protection by the Arf/p53 pathway
2007 Nature
The role of senescent cells in ageing
2014 StandoutNature
Clonal evolution in cancer
2012 StandoutNature
The Hallmarks of Aging
2013 Standout
CDK Inhibitor p18INK4c Is a Downstream Target of GATA3 and Restrains Mammary Luminal Progenitor Cell Proliferation and Tumorigenesis
2009
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Metastatic colonization by circulating tumour cells
2016 StandoutNature
DNA damage response and cellular senescence in tissues of aging mice
2009
Human DNA methylomes at base resolution show widespread epigenomic differences
2009 StandoutNature
Hematopoietic Stem Cell Trafficking
2007
Lack of Evidence that Hematopoietic Stem Cells Depend on N-Cadherin-Mediated Adhesion to Osteoblasts for Their Maintenance
2007
The Regulation of INK4/ARF in Cancer and Aging
2006
Arteriolar niches maintain haematopoietic stem cell quiescence
2013 Nature
Cdc42 Activity Regulates Hematopoietic Stem Cell Aging and Rejuvenation
2012
Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells
2006
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency
2008
Mechanisms that Regulate Stem Cell Aging and Life Span
2013
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Monitoring Tumorigenesis and Senescence In Vivo with a p16INK4a-Luciferase Model
2013
Strontium can increase some osteoblasts without increasing hematopoietic stem cells
2007
Human Mesenchymal Stem Cells Promote Survival of T Cells in a Quiescent State
2007
The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
2010 Standout
Regulation of Hematopoietic Stem Cells by the Steel Factor/KIT Signaling Pathway
2008
Reconstitution of the functional human hematopoietic microenvironment derived from human mesenchymal stem cells in the murine bone marrow compartment
2005
The relationship between bone, hemopoietic stem cells, and vasculature
2011
Ontogeny of the Hematopoietic System
2007
Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia
2007
Loss of Cxcl12/Sdf-1 in adult mice decreases the quiescent state of hematopoietic stem/progenitor cells and alters the pattern of hematopoietic regeneration after myelosuppression
2010
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Four faces of cellular senescence
2011 Standout
Cancer Genome Landscapes
2013 StandoutScience
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
Polysialic acid governs T-cell development by regulating progenitor access to the thymus
2009 StandoutNobel
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Quantum dot/antibody conjugates for in vivo cytometric imaging in mice
2015 StandoutNobel
Hematopoietic stem cell exhaustion impacted by p18INK4C and p21Cip1/Waf1 in opposite manners
2005
Ankyrin Repeat: A Unique Motif Mediating Protein−Protein Interactions
2006
Growth Factors, Matrices, and Forces Combine and Control Stem Cells
2009 StandoutScience
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
The Biology of Cancer Stem Cells
2007
Stem Cells and Their Niches
2006 Science
The Molecular Balancing Act of p16INK4a in Cancer and Aging
2013
Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation
2007
Works of Randolf Forkert being referenced
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a
2006 Nature
Oocyte Generation in Adult Mammalian Ovaries by Putative Germ Cells in Bone Marrow and Peripheral Blood
2005
Molecular analysis of candidate genes on chromosome 5q13 in autosomal recessive spinal muscular atrophy: evidence of homozygous deletions of the SMN gene in unaffected individuals
1995
Ex vivo targeting of p21Cip1/Waf1 permits relative expansion of human hematopoietic stem cells
2003
Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size
2005
Matrix Glycoprotein Osteopontin Is a Stem Cell Niche Constituent That Constrains the Hematopoietic Stem Cell Pool Size.
2004