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Citing Papers
A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles
2002 Standout
Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei
2004 Standout
Systemic CTLA-4 Blockade Ameliorates Glioma-Induced Changes to the CD4+ T Cell Compartment without Affecting Regulatory T-Cell Function
2007 StandoutNobel
Innate immune functions of microglia isolated from human glioma patients
2006
Guidelines for the welfare and use of animals in cancer research
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Selective cancer-germline gene expression in pediatric brain tumors
2008
Systemic Targeting of CpG-ODN to the Tumor Microenvironment with Anti–neu-CpG Hybrid Molecule and T Regulatory Cell Depletion Induces Memory Responses in BALB-neuT Tolerant Mice
2008 StandoutNobel
CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity
2010 StandoutNobel
Malignant glioma cells use MHC class II transactivator (CIITA) promoters III and IV to direct IFN‐γ‐inducible CIITA expression and can function as nonprofessional antigen presenting cells in endocytic processing and CD4+ T‐cell activation
2001
Transient increase in symptoms associated with cytokine release in patients with multiple sclerosis
1996
CD44: From adhesion molecules to signalling regulators
2003 Standout
Systemic cytokine administration can affect blood-brain barrier permeability in the rat
1995
Immune defects observed in patients with primary malignant brain tumors
1999
Intracavitary Placement of Autologous Lymphokine-Activated Killer (LAK) Cells after Resection of Recurrent Glioblastoma
2004
Anti-tumor activity and trafficking of self, tumor-specific T cells against tumors located in the brain
2008
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
Murine tumor necrosis factor alpha is transported from blood to brain in the mouse
1993
Use of the Oxford Handicap Scale at hospital discharge to predict Glasgow Outcome Scale at 6 months in patients with traumatic brain injury
2008
Glioblastoma and Other Malignant Gliomas
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Guillain-Barré syndrome
2016 Standout
T-cell immune responses in the brain and their relevance for cerebral malignancies
2003
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Elevated serum levels of tumor necrosis factor‐α in Guillain‐Barré syndrome
1993
A phase 3 trial of local chemotherapy with biodegradable carmustine(BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma
2003 Standout
Maternal Intrauterine Infection, Cytokines, and Brain Damage in the Preterm Newborn
1997 Standout
Improved long term survival after intracavitary interleukin-2 and lymphokine-activated killer cells for adults with recurrent malignant glioma
1995
Active immunotherapy for advanced intracranial murine tumors by using dendritic cell-tumor cell fusion vaccines
2005
A Pilot Study of Autologous Cancer Cell Vaccination and Cellular Immunotherapy Using Anti-CD3 Stimulated Lymphocytes in Patients with Recurrent Grade III/IV Astrocytoma
2000
Immunotherapy for recurrent malignant glioma: an interim report on survival
1990
Chorioamnionitis as a Risk Factor for Cerebral Palsy
2000 Standout
Immunotherapy for malignant glioma using human recombinant interleukin-2 and activated autologous lymphocytes
1990
Blood–brain barrier delivery
2006
Intratumoral LAK cell and interleukin-2 therapy of human gliomas
1989
Human microglial cells: Characterization in cerebral tissue and in primary culture, and study of their susceptibility to HIV‐1 infection
1991 StandoutNobel
Development, maintenance and disruption of the blood-brain barrier
2013 Standout
Expression of the SART3 Tumor-Rejection Antigen in Brain Tumors and Induction of Cytotoxic T Lymphocytes by Its Peptides
2000
Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys
1997 Standout
Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas
1995 Standout
The failure of current immunotherapy for malignant glioma. Tumor-derived TGF-?, T-cell apoptosis, and the immune privilege of the brain
1995
Steroid Regulation of Cytokines. Relevance for TH1‐to‐TH2 Shift?a
1994
Improving alloreactive CTL immunotherapy for malignant gliomas using a simulation model of their interactive dynamics
2007
Malignant Gliomas in Adults
2008 Standout
Pilot Study of Local Autologous Tumor Infiltrating Lymphocytes for the Treatment of Recurrent Malignant Gliomas
1999
Dendritic Cell Therapy of High‐Grade Gliomas
2009
Therapy of recurrent high grade gliomas with surgery, and autologous mitogen activated IL-2 stimulated killer (MAK) Lymphocytes: I. Enhancement of MAK lytic activity and cytokine production by PHA and clinical use of PHA
1993
bryA
2004
Expression of the tumor-rejection antigen SART1 in brain tumors
1999
Origin and physiological roles of inflammation
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Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma
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Effect of Duloxetine on Pain, Function, and Quality of Life Among Patients With Chemotherapy-Induced Painful Peripheral Neuropathy
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Neuroprotection in Cerebral Ischaemia: Facts and Fancies – The Need for New Approaches
2003
Primary brain tumours in adults
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Immunotherapy for the Treatment of Glioblastoma
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Immunotherapy of Diffuse Gliomas: Biological Background, Current Status and Future Developments
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AKT/PKB Signaling: Navigating the Network
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Elimination of regulatory T cells is essential for an effective vaccination with tumor lysate‐pulsed dendritic cells in a murine glioma model
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DENDRITIC CELL VACCINATION IN PATIENTS WITH MALIGNANT GLIOMAS
2006
Psychological Stress and the Human Immune System: A Meta-Analytic Study of 30 Years of Inquiry.
2004 Standout
Excitotoxic and Excitoprotective Mechanisms: Abundant Targets for the Prevention and Treatment of Neurodegenerative Disorders
2003
Convergent Mechanisms for Recognition of Divergent Cytokines by the Shared Signaling Receptor gp130
2003 StandoutNobel
Astrocyte–endothelial interactions at the blood–brain barrier
2005 Standout
The Pathobiology of Vascular Dementia
2013 Standout
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2012
Passive Immunotherapeutic Strategies for the Treatment of Malignant Gliomas
2012
Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6
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Cellular and Functional Characterization of Immunoresistant Human Glioma Cell Clones Selected With Alloreactive Cytotoxic T Lymphocytes Reveals Their Up-regulated Synthesis of Biologically Active TGF-β
2007
Clinically Significant Drug Interactions with Newer Antidepressants
2011
Complement recruitment using bispecific diabodies
1997 StandoutNobel
Enhancement of anti-tumor immunity by photodynamic therapy
2009
Parkinson's Disease
2003 Standout
The Biosynthetic Logic of Polyketide Diversity
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Activated monocytes kill malignant brain tumor cellsin vitro
1994
Immunogenic cell death and DAMPs in cancer therapy
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All in the head: obstacles for immune rejection of brain tumours
2002
Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner
2012 Standout
Guidelines for the Early Management of Patients With Acute Ischemic Stroke
2013 Standout
The Cholinergic Neuronal Differentiation Factor from Heart Cells Is Identical to Leukemia Inhibitory Factor
1989 Science
Use of carbon labeling to demonstrate the role of blood monocytes as precursors of the ‘ameboid cells’ present in the corpus callosum of postnatal rats
1980
CNTF Protection of Oligodendrocytes Against Natural and Tumor Necrosis Factor-Induced Death
1993 Science
Kinase AKT1 Negatively Controls Neutrophil Recruitment and Function in Mice
2013
Intensified and protective CD4+ T cell immunity in mice with anti–dendritic cell HIV gag fusion antibody vaccine
2006 StandoutNobel
Polymeric Systems for Controlled Drug Release
1999 Standout
Expansion of natural killer cells but not T cells in human interleukin 2/interleukin 2 receptor (Tac) transgenic mice.
1989 StandoutNobel
Intratumoral Chemotherapy
1995
Integrated NY-ESO-1 antibody and CD8+T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab
2011 StandoutNobel
Augmented IL-15Rα Expression by CD40 Activation Is Critical in Synergistic CD8 T Cell-Mediated Antitumor Activity of Anti-CD40 Antibody with IL-15 in TRAMP-C2 Tumors in Mice
2012 StandoutNobel
Vaccination of malignant glioma patients with peptide-pulsed dendritic cells elicits systemic cytotoxicity and intracranial T-cell infiltration.
2001
Safety and immunogenicity of a human and mouse gp100 DNA vaccine in a phase I trial of patients with melanoma.
2009
Paraquat elicited neurobehavioral syndrome caused by dopaminergic neuron loss
1999
Interferon-Beta Prevents Cytokine-Induced Neutrophil Infiltration and Attenuates Blood–Brain Barrier Disruption
2003
Evidence for the Involvement of CD44 in Endothelial Cell Injury and Induction of Vascular Leak Syndrome by IL-2
1999
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Convection-enhanced delivery of macromolecules in the brain.
1994 Standout
The TLR-7 Agonist, Imiquimod, Enhances Dendritic Cell Survival and Promotes Tumor Antigen-Specific T Cell Priming: Relation to Central Nervous System Antitumor Immunity
2006
Evidence for the Biosynthesis of Bryostatins by the Bacterial Symbiont “ Candidatus Endobugula sertula” of the Bryozoan Bugula neritina
2001
Prognostic Significance of Occult Metastases Detected by Sentinel Lymphadenectomy and Reverse Transcriptase–Polymerase Chain Reaction in Early-Stage Melanoma Patients
1999
The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells.
1994
Cellular immune reactivity within the CNS
1986
Therapeutic Benefits from Nanoparticles: The Potential Significance of Nanoscience in Diseases with Compromise to the Blood Brain Barrier
2012
Final Version of the American Joint Committee on Cancer Staging System for Cutaneous Melanoma
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Dendritic Cell Vaccination in Glioblastoma Patients Induces Systemic and Intracranial T-cell Responses Modulated by the Local Central Nervous System Tumor Microenvironment
2005
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
The Chemistry of Neutron Capture Therapy
1998 Standout
Expression of cancer testis genes in human brain tumors.
2000
Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide.
1993 StandoutNobel
Expression of MAGE and GAGE in high-grade brain tumors: a potential target for specific immunotherapy and diagnostic markers.
1999
Cellular uptake of nanoparticles: journey inside the cell
2017 Standout
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial
2010 Standout
Infectious Diseases in Pregnancy, Cytokines and Neurological Impairment: an Hypothesis
1993
Microglia in the prenatal mouse neostriatum and spinal cord.
1981
Antitumor Vaccination of Patients With Glioblastoma Multiforme: A Pilot Study to Assess Feasibility, Safety, and Clinical Benefit
2004
Proliferation of Astroglia and Oligodendroglia in Response to Human T Cell-Derived Factors
1984 Science
Detection of Brain Activation in Unresponsive Patients with Acute Brain Injury
2019
HER-2, gp100, and MAGE-1 Are Expressed in Human Glioblastoma and Recognized by Cytotoxic T Cells
2004
Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action
1999
Increased Regulatory T-Cell Fraction Amidst a Diminished CD4 Compartment Explains Cellular Immune Defects in Patients with Malignant Glioma
2006
Brain Tumors
1991
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
2008 Standout
Works of Randall E. Merchant being referenced
Cytotoxic T cells infiltrating a glioma express an aberrant phenotype that is associated with decreased function and apoptosis
2001
Adoptive immunotherapy for recurrent glioblastoma multiforme using lymphokine activated killer cells and recombinant interleukin-2
1988
Tumor infiltration by myeloid suppressor cells in response to T cell activation in rat gliomas
2005
Nonspecific Cytotoxicity of Recombinant Interleukin-2 Activated Lymphocytes
1989
Sterile abscesses in glioma patients treated by intraparenchymal injection of lymphokine-activated killer cells and recombinant interleukin-2
1989
Adoptive immunotherapy of malignant glioma using tumor-sensitized T lymphocytes
1997
Ex vivo expansion of tumor-draining lymph node cells using compounds which activate intracellular signal transduction. II. Cytokine production and in vivo efficacy of glioma-sensitized lymphocytes
1997
An Open‐Label Study of CP‐101,606 in Subjects with a Severe Traumatic Head Injury or Spontaneous Intracerebral Hemorrhage
1999
A Double‐Blind, Placebo‐Controlled Study of the Safety, Tolerability and Pharmacokinetics of CP‐101,606 in Patients with a Mild or Moderate Traumatic Brain Injury
1999
Ex vivo expansion of tumor-draining lymph node cells using compounds which activate intracellular signal transduction. I. Characterization and in vivo anti-tumor activity of glioma-sensitized lymphocytes
1997
Outcome measures for clinical trials in neurotrauma
2002
Thymic function and output of recent thymic emigrant T cells during intracranial glioma progression
2003
Histopathological and blood-brain barrier changes in rats induced by an intracerebral injection of human recombinant interleukin 2
1989
Blood-brain barrier changes following intracerebral injection of human recombinant tumor necrosis factor-? in the rat
1994
In vitro analysis of the proliferative potential of T cells from patients with brain tumor: glioma-associated immunosuppression unrelated to intrinsic cellular defect
1992
Appearance of cytokine-associated central nervous system myelin damage coincides temporally with serum tumor necrosis factor induction after recombinant interleukin-2 infusion in rats
1991
Interleukin-2 modulates the expression of lymphocyte function-associated antigen-one (LFA-1) and p150,95 during the generation of lymphokine-activated killer (LAK) cells.
1989
Molecular detection of tumor-associated antigens shared by human cutaneous melanomas and gliomas.
1997
Scanning electron microscopy of the subarachnoid space in the dog. V. Macrophages challenged by bacillus calmette‐GUERIN
1977
Basic Research Applied to Neurosurgery Lymphocyte Trafficking to the Central Nervous System: A Review of Anatomic, Immunologic, and Molecular Mechanisms
1996
Cerebrovascular Effects and Tumor Kinetics after a Single Intratumoral Injection of Human Recombinant Interleukin-2 Alone or in Combination with Intravenous Chemotherapy in a Rat Model of Glioma
1992
Scanning electron microscopy of the subarachnoid space in the dog: Evidence for a non‐hematogenous origin of subarachnoid macrophages
1979
IL-6 Secretion by a Rat T9 Glioma Clone Induces a Neutrophil-Dependent Antitumor Response with Resultant Cellular, Antiglioma Immunity
2001
Intralesional Infusion of Lymphokine-activated Killer (LAK) Cells and Recombinant Interleukin-2 (rIL-2) for the Treatment of Patients with Malignant Brain Tumor
1988
Cerebral vasomotor responses after recombinant interleukin 2 infusion.
1990
Blood-brain barrier dysfunction in cats following recombinant interleukin-2 infusion.
1987
Histopathological and Blood-Brain Barrier Changes in Rats Induced by an Intracerebral Injection of Human Recombinant Interleukin 2
1989
Glia cell stimulating factor (GSF): A new lymphokine
1982