Citation Impact
Citing Papers
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease
2010 StandoutScienceNobel
Turns in Peptides and Proteins
1985 Standout
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Residue-based control of helix shape in β-peptide oligomers
1997 Nature
The Synthesis of Cystine Peptides by Iodine Oxidation of S‐Trityl‐cysteine and S‐Acetamidomethyl‐cysteine Peptides
1980
A Catalytic Antibody Produces Fluorescent Tracers of Gap Junction Communication in Living Cells
2001 StandoutNobel
Designing polymers that mimic biomolecules
1999
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
The twists and turns of β‐peptides
1999
Bioinspired polymeric materials: in-between proteins and plastics
1999
Exploring privileged structures: the combinatorial synthesis of cyclic peptides
2002
“Click chemistry”en route to pseudo-starch
2005
Design, synthesis and biological evaluation of nonpeptide integrin antagonists
1998
Direct Catalytic Asymmetric Three‐Component Kabachnik–Fields Reaction
2008 StandoutNobel
Design criteria for molecular mimics of fragments of the β-turn. 2. Cα–Cβ bond vector analysis
1999
An Inhibitor of Ribosomal Peptidyl Transferase Using the Transition-State Analogy
1995
Synthetic applications of aliphatic unsaturated α-H-α-amino acids
2005
Novel biopolymers for drug discovery
1995
Weakly Polar Interactions In Proteins
1988
Predicting protein structures with a multiplayer online game
2010 StandoutNatureNobel
Design of Peptides and Proteins
1988
Designed molecules that fold to mimic protein secondary structures
1999
The design and synthesis of substituted biphenyl libraries
1996
Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide
1996 StandoutNobel
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
Comprehensive survey of chemical libraries yielding enzyme inhibitors, receptor agonists and antagonists, and other biologically active agents: 1992 through 1997
1997
Synthesis of Pseudopeptides with Sulfoximines as Chiral Backbone Modifying Elements
2001
Design criteria for molecular mimics of fragments of the β-turn. 1. Cα atom analysis
1999
A surprising simplicity to protein folding
2000 StandoutNatureNobel
Crystallographic Analysis of the Recognition of a Nuclear Localization Signal by the Nuclear Import Factor Karyopherin α
1998 StandoutNobel
Synthesis of triazole-linked pseudo-starch fragments
2006
Ribosome Structure and the Mechanism of Translation
2002 StandoutNobel
Organic Azides: An Exploding Diversity of a Unique Class of Compounds
2005 Standout
A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein β-adaptin
1991 StandoutNatureNobel
An Unnatural Biopolymer
1993 Science
Orally Absorbed Cyclic Peptides
2017
Stereochemical Control of Hairpin Formation in β-Peptides Containing Dinipecotic Acid Reverse Turn Segments
2000
Spectral diffusion of individual pentacene molecules in P-terphenyl crystal: Stochastic theoretical model and analysis of experimental data
1995
Nonpeptidic Foldamers from Amino Acids: Synthesis and Characterization of 1,3-Substituted Triazole Oligomers
2005
β-Peptide Foldamers: Robust Helix Formation in a New Family of β-Amino Acid Oligomers
1996
Peptide segment ligation strategy without use of protecting groups.
1994
Identification of L-methionine S-sulfoximine as the diastereoisomer of L-methionine SR-sulfoximine that inhibits glutamine synthetase
1969 StandoutNobel
Synthesis and Conformational Analysis of Linear and Cyclic Peptides Containing Sugar Amino Acids
1996
Protein Structure Determination in Solution by Nuclear Magnetic Resonance Spectroscopy
1989 StandoutScienceNobel
Isolation and characterization of somatostatin from pigeon pancreas.
1979
β-Turn mimetic library synthesis: scaffolds and applications
2001
Peptidomimetics—Tailored Enzyme Inhibitors
1994
Protein β-turn mimetics I. Design, synthesis, and evaluation in model cyclic peptides.
1993
A short synthesis of the trisaccharide building block of the N-linked glycans
2003
Principles that Govern the Folding of Protein Chains
1973 StandoutScienceNobel
NMR sequential assignments and solution structure of chlorotoxin, a small scorpion toxin that blocks chloride channels.
1969
Synthesis of Amidines Derived from Phosphonates and Phosphane Oxides − Amidine‐Mediated Preparation of Phosphorylated Oxazolines
2003
Hypothalamic Regulatory Hormones
1973 StandoutScienceNobel
Chemical Glycobiology
2001 StandoutScienceNobel
Artificial β-sheets
1996
Nonionic Analogs of RNA with Dimethylene Sulfone Bridges
1996
Amino acid sequence of homologous rat atrial peptides: natriuretic activity of native and synthetic forms.
1984
The Structural Basis of Ribosome Activity in Peptide Bond Synthesis
2000 StandoutScienceNobel
Coat Proteins and Vesicle Budding
1996 StandoutScienceNobel
Determination of D- and L-Amino Acids by Ion Exchange Chromatography as L-D and L-L Dipeptides
1968
The Amino Acid Sequence of a Peptide with Growth Hormone-releasing Activity Isolated from Porcine Hypothalamus
1971 StandoutNobel
Receptors compete for adaptors found in plasma membrane coated pits.
1988
Luteinizing hormone-releasing hormone (LH-RH) activity of some synthetic polypeptides. I. Fragments shorter than decapeptide
1972 StandoutNobel
Immune Versus Natural Selection: Antibody Aldolases with Enzymic Rates But Broader Scope
1997 StandoutScienceNobel
Computer simulation of protein folding
1975 StandoutNatureNobel
Biological activity of a synthetic decapeptide corresponding to the proposed growth hormone-releasing hormone
1972 StandoutNobel
β-Peptides: From Structure to Function
2001 Standout
Molecular Matchmakers
1993 StandoutScienceNobel
Protein Assembly by Orthogonal Chemical Ligation Methods
2003
Evidence for the Conformation of the Pathologic Isoform of the Prion Protein Enciphering and Propagating Prion Diversity
1996 StandoutScienceNobel
Peptide-sugar hybrids: Like peptide, like oligosaccharide
1997
Hydrogen bonding in noncovalent synthesis: selectivity and the directed organization of molecular strands
2001
Bioactive Conformation of Luteinizing Hormone-Releasing Hormone: Evidence from a Conformationally Constrained Analog
1980 Science
Quantitative determination of D- and L-amino acids by reaction with tert-butyloxycarbonyl-L-leucine N-hydroxysuccinimide ester and chromatographic separation as L,D and L,L dipeptides
1978 StandoutNobel
Ribonuclease A
1998
A Field Guide to Foldamers
2001 Standout
Illuminating Single Molecules in Condensed Matter
1999 StandoutScienceNobel
Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
1986 StandoutNatureNobel
Progress in Modeling of Protein Structures and Interactions
2005 StandoutScienceNobel
Peptide Binding and Release by Proteins Implicated as Catalysts of Protein Assembly
1989 StandoutScienceNobel
Reversible Optical Transcription of Supramolecular Chirality into Molecular Chirality
2004 StandoutScienceNobel
Growth Hormone-Releasing Factor from a Human Pancreatic Tumor That Caused Acromegaly
1982 StandoutScienceNobel
β-turn topography
1993
Aza-Wittig reaction of N-phosphorylalkyl phosphazenes with carbonyl compounds and phenylisocyanate. Synthesis of 4-amino-3-phosphoryl-2-azadienes and pyrazine-phosphonates
2003
Recent Developments in the Chemistry of Polyvalent Iodine Compounds
2002
Protein Sorting by Transport Vesicles
1996 StandoutScienceNobel
Trapping a transition state in a computationally designed protein bottle
2015 StandoutScienceNobel
Crystal structure of leucine-enkephalin
1983 StandoutNatureNobel
Opiate receptor subclasses differ in their conformational requirements
1982 Nature
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
A Bovine Hypothalamic Peptide Possessing Immunoreactive Growth Hormone-Releasing Activity*
1978
Menschliches Calcitonin. VI. Die Synthese von Calcitonin M
1970
From Peptides to Non-Peptide Peptidomimetics: Design and Synthesis of New Piperidine Inhibitors of Aspartic Peptidases
2001
Conformational Analysis of Reverse-Turn Constraints by N-Methylation and N-Hydroxylation of Amide Bonds in Peptides and Non-Peptide Mimetics
1998
From Molecular Diversity to Catalysis: Lessons from the Immune System
1995 Science
Clathrin: A Role in the Intracellular Retention of a Golgi Membrane Protein
1989 StandoutScienceNobel
Structural Conservation in Prokaryotic and Eukaryotic Potassium Channels
1998 StandoutScienceNobel
Preparation of N‐Fmoc‐Protected β2‐ and β3‐Amino Acids and their use as building blocks for the solid‐phase synthesis of β‐peptides
1998
Affinity purification of synthetic peptides.
1976 StandoutNobel
Improved treatment of cyclic ?-amino acids and successful prediction of ?-peptide secondary structure using a modified force field: AMBER*C
2000
Peptidomimetics for Receptor Ligands—Discovery, Development, and Medical Perspectives
1993
Synthesis and Applications of Small Molecule Libraries
1996
Optical modification of a single impurity molecule in a solid
1992 StandoutNatureNobel
Foldamers: A Manifesto
1998 Standout
Solid-Phase Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries
2000
Comprehensive Survey of Combinatorial Library Synthesis: 2000
2001
Nuclear Magnetic Resonance Spectroscopy of Amino Acids, Peptides, and Proteins
1970
The “One-Bead-One-Compound” Combinatorial Library Method
1997
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
A Solid-Phase Approach to Mouse Melanocortin Receptor Agonists Derived from a Novel Thioether Cyclized Peptidomimetic Scaffold
2002 StandoutNobel
Hole and antihole profiles in nonphotochemical hole-burned spectra
1989
The Synthesis of Ribonuclease A
1971 StandoutNobel
The Synthesis of Biologically Active Peptides and Proteins
1969 StandoutNobel
Cyclic Tetrapeptides from Nature and Design: A Review of Synthetic Methodologies, Structure, and Function
2019
Somatostatin: Abundance of Immunoreactive Hormone in Rat Stomach and Pancreas
1975 StandoutScienceNobel
NMR-Based Quantification of β-Sheet Populations in Aqueous Solution through Use of Reference Peptides for the Folded and Unfolded States
1999
Synthesis and Structural Characterization of Helix-Forming β-Peptides: trans-2-Aminocyclopentanecarboxylic Acid Oligomers
1999
Purification and Properties of Semisynthetic Staphylococcal Nuclease-T'
1971
A Simple Procedure for Connecting Two Carbohydrate Moieties by Click Chemistry Techniques
2007
Partially Modified Retro-Inverso Peptides: Development, Synthesis, and Conformational Behavior
1998
Works of Ralph Hirschmann being referenced
Design and synthesis of peptidomimetic inhibitors of HIV-1 protease and renin. Evidence for improved transport
1994
Molecular modeling, synthesis, and structures of N-methylated 3,5-linked pyrrolin-4-ones toward the creation of a privileged nonpeptide scaffold
1999
Azide and Cyanide Displacements via Hypervalent Silicate Intermediates
1999
Peptide Synthesis Catalyzed by an Antibody Containing a Binding Site for Variable Amino Acids
1994 Science
A second-generation synthesis of scalemic 3,5,5-trisubstituted pyrrolin-4-ones: Incorporation of functionalized amino acid side-chains
1997
A super active cyclic hexapeptide analog of somatostatin
1984
Conformationally restricted bicyclic analogs of somatostatin.
1978
Controlled synthesis of peptides in aqueous medium. III. Use of Leuch's anhydrides in the synthesis of di-peptides. Mechanism and control of side reactions
1967
Hole burning of long-chain molecular aggregates: homogeneous line broadening, spectral-diffusion broadening, and pressure broadening
1992
LACTAM RESTRICTION OF PEPTIDE CONFORMATION IN CYCLIC HEXAPEPTIDES WHICH ALTER RUMEN FERMENTATION
1980
Synthesis of a proposed growth hormone releasing factor
1971
Design, synthesis, and crystal structure of a pyrrolinone-based peptidomimetic possessing the conformation of a .beta.-strand: potential application to the design of novel inhibitors of proteolytic enzymes
1992
Synthesis of Potent Cyclic Hexapeptide NK-1 Antagonists. Use of a Minilibrary in Transforming a Peptidal Somatostatin Receptor Ligand into an NK-1 Receptor Ligand via a Polyvalent Peptidomimetic
1996
Medicinal Chemistry in the Golden Age of Biology: Lessons from Steroid and Peptide Research
1991
Novel Ligands Lacking a Positive Charge for the δ- and μ-Opioid Receptors
2000
Cyclic peptide formation catalyzed by an antibody ligase
2000
On the low energy solution conformation of somatostatin
1981
Total synthesis of an enzyme. I. Objective and strategy
1969
A potent cyclic hexapeptide analogue of somatostatin
1981 Nature
De Novo Design, Synthesis, and X-ray Crystal Structures of Pyrrolinone-Based .beta.-Strand Peptidomimetics
1994
Die Medizinische Chemie im Goldenen Zeitalter der Biologie: Lehren aus der Steroid‐ und Peptidforschung
1991
The Controlled Synthesis of Peptides in Aqueous Medium. I. The Use of α-Amino Acid N-Carboxyanhydrides
1966
Total synthesis of an enzyme. IV. Factors affecting the conversion of protected S-protein to ribonuclease S'
1969
First Generation Design, Synthesis, and Evaluation of Azepine-Based Cryptophycin Analogues
2001
Development of an Efficient, Regio- and Stereoselective Route to Libraries Based on the β-d -Glucose Scaffold
2000
The synthesis of peptides in aqueous medium, IV. A novel protecting group for cysteine
1968
Inferences about the conformation of somatostatin at a biologic receptor based on NMR studies
1978
Modulation of Receptor and Receptor Subtype Affinities Using Diastereomeric and Enantiomeric Monosaccharide Scaffolds as a Means to Structural and Biological Diversity. A New Route to Ether Synthesis
1998
Dihydrofolate reductase: the amino acid sequence of the enzyme from a methotrexate-resistant mutant of Escherichia coli
1978
Total synthesis of an enzyme. V. Preparation of enzymatically active material
1969
Design and Synthesis of Novel Scaffolds for Drug Discovery: Hybrids of β-d -Glucose with 1,2,3,4-Tetrahydrobenzo[e][1,4]diazepin-5-one, the Corresponding 1-Oxazepine, and 2- and 4-Pyridyldiazepines
2001
The versatile steroid nucleus: Design and synthesis of a peptidomimetic employing this novel scaffold.
1993
Synthesis of a Substance P Antagonist with a Somatostatin Scaffold: Factors Affecting Agonism/Antagonism at GPCRs and the Role of Pseudosymmetry
2000
Hole burning in excitonic states of long-chain molecular aggregates
1988
De novo design and synthesis of somatostatin non-peptide peptidomimetics utilizing .beta.-D-glucose as a novel scaffolding
1993
Acetamidomethyl. A Novel Thiol Protecting Group for Cysteine
1972
Nonpeptidal peptidomimetics with .beta.-D-glucose scaffolding. A partial somatostatin agonist bearing a close structural relationship to a potent, selective substance P antagonist
1992
The first design and synthesis of a steroidal peptidomimetic. The potential value of peptidomimetics in elucidating the bioactive conformation of peptide ligands
1992
Pyrrolinone-Based HIV Protease Inhibitors. Design, Synthesis, and Antiviral Activity: Evidence for Improved Transport
1995
A Second-Generation Synthesis of Polypyrrolinone Nonpeptidomimetics: Prelude to the Synthesis of Polypyrrolinones on Solid Support
2000
Synthesis of Polypyrrolinones on Solid Support
2000