Citation Impact
Citing Papers
Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society
2016 Standout
Transition from inflammation to proliferation: a critical step during wound healing
2016 Standout
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Ferroptosis: Death by Lipid Peroxidation
2015 Standout
Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
2004 Standout
Synthesis, inhibitory activity towards human leukocyte elastase and molecular modelling studies of 1-carbamoyl-4-methyleneaminoxyazetidinones
2000
Animal models of chronic obstructive pulmonary disease
2008
Synthetic Inhibitors of Elastase
1994
Functional Selectivity and Classical Concepts of Quantitative Pharmacology
2006 StandoutNobel
International Union of Pharmacology XXXVII. Nomenclature for Leukotriene and Lipoxin Receptors
2003
Leukotriene antagonism in asthma and rhinitis
1998
Tumor necrosis factor α stimulates leukotriene production in vivo
1988 StandoutNobel
Effect of BI-L-239, A-64077 and MK-886 on leukotriene B4 synthesis by chopped guinea pig lung and on antigen-induced tracheal contraction
1992
Inflammation in Wound Repair: Molecular and Cellular Mechanisms
2007 Standout
Mechanisms of neurotransmitter release by amphetamines: A review
2005 Standout
The leukotriene D4-receptor antagonist, ICI 204,219, relieves symptoms of acute seasonal allergic rhinitis.
1995
Peptidomimetics derived from natural products
1993
Effect of cysteinyl-leukotriene receptor antagonist ICI 204.219 on allergen-induced bronchoconstriction and airway hyperreactivity in atopic subjects
1991
Novel Docosatrienes and 17S-Resolvins Generated from Docosahexaenoic Acid in Murine Brain, Human Blood, and Glial Cells
2003 Standout
Empiric treatment of hospital-acquired lower respiratory tract infections with meropenem or ceftazidime with tobramycin
1997
Dynamic mechanisms of non-classical antagonism by competitive AT1 receptor antagonists
2000
Effectiveness and tolerability of zafirlukast for the treatment of asthma in children
2000
Allergic Rhinitis and Its Impact on Asthma
2001 Standout
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
Intracellular signaling in the regulation of renal Na-K-ATPase. II. Role of eicosanoids.
1993
2 Inhibitors of Human Leukocyte Elastase
1994
Pharmacological investigation of the role of leukotrienes in the pathogenesis of experimental NSAID gastropathy
1992
The Challenge of Penicillin-Resistant Streptococcus pneumoniae Meningitis: Current Antibiotic Therapy in the 1990s
1997
Biochemical mechanisms of drug action: what does it take for success?
2004
How were new medicines discovered?
2011 Standout
Eicosanoids and asthma: an update
1995
The immunology of stroke: from mechanisms to translation
2011 Standout
COPD, a multicomponent disease: implications for management
2005
The Art of Fusion: From Penams and Cephems to Penems
2003
Identification, Molecular Cloning, Expression, and Characterization of a Cysteinyl Leukotriene Receptor
1999
Gastrointestinal Toxicity of Nonsteroidal Antiinflammatory Drugs
1999 Standout
Global strategy for asthma management and prevention: GINA executive summary
2007 Standout
Neutrophil elastase and neurovascular injury following focal stroke and reperfusion
2009
Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide
1996 StandoutNobel
Specificity, stability, and potency of monocyclic .beta.-lactam inhibitors of human leukocyte elastase
1992
Mechanism of inhibition of human leukocyte elastase by monocyclic .beta.-lactams
1993
The Glut athione S-Transferase Supergene Family: Regulation of GST and the Contribution of the lsoenzymes to Cancer Chemoprotection and Drug Resistance Part I
1995 Standout
Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies
2006 Standout
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsìveness, and the late asthmatic response
2000 Standout
Isolated Bronchi from Asthmatics Are Hyperresponsive to Adenosine, which Apparently Acts Indirectly by Liberation of Leukotrienes and Histamine
1992
Asthma
2000 Standout
Zafirlukast Improves Asthma Control in Patients Receiving High-Dose Inhaled Corticosteroids
2000
Pharmacological Characterization of Leukotriene Receptors
2000
Effects of LTD 4 on Human Airway Smooth Muscle Cell Proliferation, Matrix Expression, and Contraction In Vitro : Differential Sensitivity to Cysteinyl Leukotriene Receptor Antagonists
1998
The Pathobiology of Bronchial Asthma
1992
Noradrenaline binding and the search for catecholamine receptors
1974 Nature
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
Activation of A3 adenosine receptors on human eosinophils elevates intracellular calcium
1996 StandoutNobel
Non-Peptide Gonadotropin-Releasing Hormone Receptor Antagonists
2008
Pulmonary rehabilitation for chronic obstructive pulmonary disease
2015 Standout
Effect of catechol-O-methyl-transferase (COMT) inhibition on the vascular and metabolic responses to noradrenaline, isoprenaline and sympathetic nerve stimulation in canine subcutaneous adipose tissue
1977
Relationship between structure and convulsant properties of some beta-lactam antibiotics following intracerebroventricular microinjection in rats
1995
Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease
2011
Cyclooxygenases: Structural, Cellular, and Molecular Biology
2000 Standout
Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
2016 Standout
Biological activity of WIN 63759, an orally bioavailable inhibitor of human neutrophil elastase
1995
Binding of (125I)iodohydroxybenzylpindolol to putative beta-adrenergic receptors of rat glioma cells and other cell clones.
1976 StandoutNobel
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Bacterial Resistance to β-Lactam Antibiotics: Compelling Opportunism, Compelling Opportunity
2005 Standout
Fibronectin Degradation in Chronic Wounds Depends on the Relative Levels of Elastase, α1-Proteinase Inhibitor, and α2-Macroglobulin
1996
In Vitro Desensitization of Beta Adrenergic Receptors in Human Neutrophils. ATTENUATION BY CORTICOSTEROIDS
1983 StandoutNobel
Peptidoleukotrienes: Distinct receptors for leukotriene C4 and D4 in the Guinea-pig lung
1983
Potentiation of the effects of isoprenaline and noradrenaline by hydrocortisone in cat heart muscle
1972
The ß-adrenergic receptor and adenylate cyclase
1976 StandoutNobel
Steroid potentiation of responses to sympathomimetic amines in aortic strips
1969
Effect of the Novel Synthetic Protease Inhibitor Furoyl Saccharin on Elastase-Induced Emphysema in Rabbits and Hamsters
1986
Adipocyte beta-adrenergic receptors. Identification and subcellular localization by (-)-[3H]dihydroalprenolol binding.
1976 StandoutNobel
[3H]norepinephrine binding and lipolysis by isolated fat cells
1974 StandoutNobel
Identification of adenylate cyclase-coupled beta-adrenergic receptors with radiolabeled beta-adrenergic antagonists
1975 StandoutNobel
Inhibitors of human leukocyte elastase. 2.1 synthesis and sar of benzisothiazolinylmethyl aryl ethers
1995
Characterization of a leukotriene D4 receptor in guinea pig lung.
1983
How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions*
2000 Standout
[3H]Norepinephrine binding: Unrelated to catechol-o-methyl transferase
1974 StandoutNobel
Penetration of Drugs through the Blood-Cerebrospinal Fluid/Blood-Brain Barrier for Treatment of Central Nervous System Infections
2010 Standout
Protease Inhibitors: Current Status and Future Prospects
2000
Nonpeptidic Inhibitors of Human Neutrophil Elastase. 7. Design, Synthesis, and in Vitro Activity of a Series of Pyridopyrimidine Trifluoromethyl Ketones
1996
Microsomal glutathione S-transferase is the predominant leukotriene C4 binding site in cellular membranes.
1994
Absolute stereochemistries and total synthesis of (+)/(−)-macrosphelides, potent, orally bioavailable inhibitors of cell–cell adhesion
2005 StandoutNobel
Kinetic analysis of the interaction between noradrenaline and Na+ in neuronal uptake: Kinetic evidence for CO-transport
1979
Leukotrienes and Lipoxins: Structures, Biosynthesis, and Biological Effects
1987 StandoutScienceNobel
Identification of cardiac beta-adrenergic receptors by (minus) [3H]alprenolol binding.
1975 StandoutNobel
Solid-Phase Library Synthesis, Screening, and Selection of Tight-Binding Reduced Peptide Bond Inhibitors of a RecombinantLeishmaniamexicanaCysteine Protease B
2002 StandoutNobel
Practice Guidelines for the Management of Bacterial Meningitis
2004 Standout
Corticosteroid-Induced Differential Regulation of β-Adrenergic Receptors in Circulating Human Polymorphonuclear Leukocytes and Mononuclear Leukocytes*
1980 StandoutNobel
Heterogeneity of adenylate cyclase-coupled β-adrenergic receptors
1975 StandoutNobel
Identification of beta-adrenergic receptors in human lymphocytes by (-) (3H) alprenolol binding.
1976 StandoutNobel
Catecholamine binding to the beta-adrenergic receptor.
1977 StandoutNobel
The β-adrenergic receptor
1976 StandoutNobel
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
A benzisothiazolone class of potent, selective mechanism-based inhibitors of human leukocyte elastase
1994
Dopamine Receptors: From Structure to Function
1998 Standout
AUTONOMIC PHARMACOLOGY OF LEUKOTRIENES
1985
Relation of Body Fat Distribution to Metabolic Complications of Obesity*
1982 Standout
Works of Ralph E. Giles being referenced
A COMPARISON OF CERTAIN PROPERTIES OF CATECHOL-O-METHYL TRANSFERASE TO THOSE OF ADRENERGIC BETA RECEPTORS
1967
In vivo pharmacology of ICI 198,615: a novel, potent and selective peptide leukotriene antagonist.
1987
In vitro pharmacology of ICI 198,615: a novel, potent and selective peptide leukotriene antagonist.
1987
Biologic Characterization of ICI 200,880 and ICI 200,355, Novel Inhibitors of Human Neutrophil Elastase
1991
The Preclinical Pharmacology of ICI 204,219: A Peptide Leukotriene Antagonist
1990
Meropenem: evidence of lack of proconvulsive tendency in mice
1989
Biochemical and Pharmacological Characterization of the Binding of the Selective Peptide‐Leukotriene Antagonist, 3H‐ICI 198,615, to Leukotriene D4 Receptors in Guinea‐Pig Lung Membranes
1988
Biochemistry and Pharmacology of ICI 200,880, a Synthetic Peptide Inhibitor of Human Neutrophil Elastase
1991
Biochemical and pharmacological characterization of ICI 198,615: a peptide leukotriene receptor antagonist
1989
Studies on the potentiation of the inotropic actions of certain catecholamines by U-0521 (3',4'-dihydroxy-alpha-methyl propiophenone).
1967
ICI 147,798: a slowly dissociable beta adrenoceptor antagonist that causes insurmountable beta-1 and surmountable beta-2 adrenoceptor antagonism in isolated tissues.
1989
Heterogeneity of leukotriene receptions in guinea-pig trachea
1983
The Therapeutic Effect of Progesterone in Papain-Induced Emphysema
1974
THE CATECHOL-O-METHYL TRANSFERASE ACTIVITY AND ENDOGENOUS CATECHOLAMINE CONTENT OF VARIOUS TISSUES IN THE RAT AND THE EFFECT OF ADMINISTRATION OF U-0521 (3’,4’-DIHYDROXY-2-METHYL PROPIOPHENONE)
1967
Progesterone Antagonism of Papain Emphysema: Role of Sex, Estrogens and Serum Antitrypsin
1973