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Cytotoxic drug penetration studies in multicellular tumour spheroids
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Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide]
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Perivascular oxygen tensions in a transplantable mammary tumor growing in a dorsal flap window chamber.
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Heterogeneity of cellular glutathione among cells derived from a murine fibrosarcoma or a human renal cell carcinoma detected by flow cytometric analysis.
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Resistance to vincristine of human cells grown as multicellular spheroids
1980
Resistance to adriamycin in multicellular spheroids
1979
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Use of Hoechst 33342 for cell selection from multicell systems.
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1996
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1988 StandoutScience
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1979
Variable Radiobiological Responses of Spheroids
1980
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Tumor distribution of bromodeoxyuridine-labeled cells is strongly dose dependent.
2003
Doxorubicin gradients in human breast cancer.
1999
Intracapillary oxyhemoglobin saturation of malignant tumors in humans
1981
Multistage nanoparticle delivery system for deep penetration into tumor tissue
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Slug is a direct Notch target required for initiation of cardiac cushion cellularization
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Penetration and binding of vinblastine and 5-fluorouracil in cellular spheroids
1984
Determinants of Paclitaxel Penetration and Accumulation in Human Solid Tumor
1999
Oxygen dependence of the cytotoxicity and metabolic activation of 4-alkylamino-5-nitroquinoline bioreductive drugs
1994
Aspects of cytotoxic drug penetration, with particular reference to anthracyclines
1987
Tumor hypoxia: its impact on cancer therapy
1987
Quantum dot/antibody conjugates for in vivo cytometric imaging in mice
2015 StandoutNobel
Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.
1994
Growth Factors, Matrices, and Forces Combine and Control Stem Cells
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Development of Apoptosis and Polyploidy in Human Lymphoblast Cells as a Function of Position in the Cell Cycle at the Time of Irradiation
1996
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2004
Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis.
1995
Prediction of Tumour Tissue Diffusion Coefficients of Hypoxia-Activated Prodrugs from Physicochemical Parameters
2008
Penetration of anticancer drugs through solid tissue: a factor that limits the effectiveness of chemotherapy for solid tumors.
1999
Works of Ralph E. Durand being referenced
Orally administered pimonidazole to label hypoxic tumor cells.
2002
Radiosensitization of hypoxic cells of an in vitro tumor model by respiratory inhibitors.
1977
Physiologic and cytotoxic effects of tirapazamine in tumor-bearing mice
1997
Resistance of tumor cells to chemo- and radiotherapy modulated by the three-dimensional architecture of solid tumors and spheroids
2001
Contribution of Transient Blood Flow to Tumour Hypoxia in Mice
1995
The use of fluorescent probes to identify regions of transient perfusion in murine tumors
1989
Repopulation characteristics and cell kinetic parameters resulting from multi-fraction irradiation of xenograft tumors in SCID mice
1999
Intermittent Blood Flow in Solid Tumours – an under-appreciated Source of ‘drug Resistance’
2001
Evaluation of bioreductive drugs in multicell spheroids
1992
Keynote address: The influence of microenvironmental factors on the activity of radiation and drugs
1991
The Range of Oxygenation in SiHa Tumor Xenografts
2002
Chapter 45 Cell Sorting with Hoechst or Carbocyanine Dyes as Perfmion Probes in Spheroids and Tumors
1990
Slow penetration of anthracyclines into spheroids and tumors: a therapeutic advantage?
1990
Drug and radiation resistance in spheroids: cell contact and kinetics
1994
Repair and reoxygenation following irradiation of an in vitro tumor model
1976
The Effects of Nitrobenzene Derivatives on Oxygen Utilization and Radiation Response of an in Vitro Tumor Model
1976
Heterogeneity in Radiation-Induced DNA Damage and Repair in Tumor and Normal Cells Measured Using the “Comet” Assay
2012
Cell contact as a possible contribution to radiation resistance of some tumours
1972
Spheroids in Cancer Research
1984
The Radiation Response of Asynchronous Cells at Low Dose: Evidence of Substructure
1991
Quantifying Transient Hypoxia in Human Tumor Xenografts by Flow Cytometry
2004
Adriamycin: A Possible Indirect Radiosensitizer of Hypoxic Tumor Cells
1976
Fluorescent nitroheterocycles for identifying hypoxic cells.
1983
Flow cytometry studies of intracellular adriamycin in single cells in vitro.
1981
Notch Activation Results in Phenotypic and Functional Changes Consistent With Endothelial-to-Mesenchymal Transformation
2004
Flow Cytometry Techniques for Studying Cellular Thiols
1983
The Enhanced Radiation Response of anin VitroTumour Model by Cyanide Released from Hydrolysed Amygdalin
1978
Flow cytometry techniques for studying cellular thiols.
1983
Heterogeneity in Radiation-Induced DNA Damage and Repair in Tumor and Normal Cells Measured Using the "Comet" Assay
1990
Radiosensitization of Hypoxic Cells of an in Vitro Tumor Model by Respiratory Inhibitors
1977
Hypoxic Cells in anin VitroTumour Model
1973
Combination adriamycin/misonidazole toxicity in V79 spheroids
1982
Cell killing, radiosensitization and cell cycle redistribution induced by chronic hypoxia
1984
Flow cytometry studies of intracellular adriamycin in multicell spheroids in vitro.
1981
Effect of Intercellular Contact on DNA Conformation, Radiation-Induced DNA Damage, and Mutation in Chinese Hamster V79 Cells
1985
Isolation of cell subpopulations from in vitro tumor models according to sedimentation velocity.
1975
Sequencing radiation and adriamycin exposures in spheroids to maximize therapeutic gain
1989
Dependence of the radiation response of an in vitro tumor model on cell cycle effects.
1973
Characterization of radiolabeled fluoromisonidazole as a probe for hypoxic cells.
1987
Characterization of Radiolabeled Fluoromisonidazole as a Probe for Hypoxic Cells
1987
Intermittent blood flow in a murine tumor: radiobiological effects.
1987