Standout Papers
- Structural Basis of Transcription: An RNA Polymerase II-TFIIB Cocrystal at 4.5 Angstroms (2004)
- A Complex of the Srb8, -9, -10, and -11 Transcriptional Regulatory Proteins from Yeast (2002)
- Quantitation of the RNA Polymerase II Transcription Machinery in Yeast (2001)
- Structural basis of eukaryotic gene transcription (2004)
Citation Impact
Citing Papers
Confirmation of intersubunit connectivity and topology of designed protein complexes by native MS
2018 StandoutNobel
Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking
2007 StandoutNobel
Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution
2009 StandoutScienceNobel
Schizosacharomyces pombe RNA polymerase II at 3.6-Å resolution
2009 Nobel
RNA polymerase II trigger loop residues stabilize and position the incoming nucleotide triphosphate in transcription
2010 StandoutNobel
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
2020 StandoutScienceNobel
The diverse and expanding role of mass spectrometry in structural and molecular biology
2016
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
A Bayesian View on Cryo-EM Structure Determination
2011
Structural insight into the TFIIE–TFIIH interaction: TFIIE and p53 share the binding region on TFIIH
2008
High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy
2013 StandoutNobel
A stomatin-like protein necessary for mechanosensation in C. elegans
1995 StandoutNatureNobel
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Structural Basis for Gating and Activation of RyR1
2016 StandoutNobel
The ϕ29 DNA polymerase:protein‐primer structure suggests a model for the initiation to elongation transition
2006 StandoutNobel
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis
2006 StandoutNobel
EGL-10 Regulates G Protein Signaling in the C. elegans Nervous System and Shares a Conserved Domain with Many Mammalian Proteins
1996 StandoutNobel
In vivo dynamics of RNA polymerase II transcription
2007
Structures of Complete RNA Polymerase II and Its Subcomplex, Rpb4/7
2005
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Genome-Wide Location of the Coactivator Mediator: Binding without Activation and Transient Cdk8 Interaction on DNA
2006
Expression of a glutamate-activated chloride current in Xenopus oocytes injected with Caenorhabditis elegans RNA: evidence for modulation by avermectin
1992
Chemosensation in C. elegans
2006
Visualizing polynucleotide polymerase machines at work
2006 StandoutNobel
Mapping the Location of TFIIB within the RNA Polymerase II Transcription Preinitiation Complex
2004
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
Ab initio construction of protein tertiary structures using a hierarchical approach
2000 StandoutNobel
The Role of the Transcription Bubble and TFIIB in Promoter Clearance by RNA Polymerase II
2005
Dynamic regulation of pol II transcription by the mammalian Mediator complex
2005
Genome-Wide Occupancy Profile of Mediator and the Srb8-11 Module Reveals Interactions with Coding Regions
2006
What recent ribosome structures have revealed about the mechanism of translation
2009 StandoutNatureNobel
The RNA Polymerase II Machinery
2002
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
2017 StandoutNatureNobel
RNA polymerase II–TFIIB structure and mechanism of transcription initiation
2009 Nature
An Alternatively Spliced C. elegans ced-4 RNA Encodes a Novel Cell Death Inhibitor
1996 StandoutNobel
SIMPLE: Software for ab initio reconstruction of heterogeneous single-particles
2012
Gene interactions affecting mechanosensory transduction in Caenorhabditis elegans
1994 StandoutNatureNobel
Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant
2000 StandoutNatureNobel
Identification of genes expressed in C. elegans touch receptor neurons
2002 StandoutNatureNobel
A DNA-tethered cleavage probe reveals the path for promoter DNA in the yeast preinitiation complex
2006
Intermediate states during mRNA–tRNA translocation
2012 StandoutNobel
Structure and mechanism of the RNA polymerase II transcription machinery
2004
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS
2004
RNA Polymerase II/TFIIF Structure and Conserved Organization of the Initiation Complex
2003 StandoutNobel
PRIME: Probabilistic Initial 3D Model Generation for Single-Particle Cryo-Electron Microscopy
2013
Inhibition of Bacterial RNA Polymerase by Streptolydigin: Stabilization of a Straight-Bridge-Helix Active-Center Conformation
2005
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
NMR analysis of a 900K GroEL–GroES complex
2002 StandoutNatureNobel
Identification of Two Distinct Hybrid State Intermediates on the Ribosome
2007
Likelihood-based classification of cryo-EM images using FREALIGN
2013
Elongation by RNA polymerase II: the short and long of it
2004
Transcriptional noise and the fidelity of initiation by RNA polymerase II
2007
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
The Structure of a Transcribing T7 RNA Polymerase in Transition from Initiation to Elongation
2008 StandoutScienceNobel
Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation
2013 StandoutNobel
mec-7 is a beta-tubulin gene required for the production of 15-protofilament microtubules in Caenorhabditis elegans.
1989 StandoutNobel
Structural characterization of mRNA-tRNA translocation intermediates
2012 StandoutNobel
Diffusion of nucleoside triphosphates and role of the entry site to the RNA polymerase II active center
2004 StandoutNobel
Cdk8 Is Essential for Preimplantation Mouse Development
2007
The zebrafish kohtalo/trap230 gene is required for the development of the brain, neural crest, and pronephric kidney
2005
Green Fluorescent Protein as a Marker for Gene Expression
1994 StandoutScienceNobel
A common muscarinic pathway for diapause recovery in the distantly related nematode species Caenorhabditis elegans and Ancylostoma caninum
2000 StandoutNobel
Neurobiology of the Caenorhabditis elegans Genome
1998 Science
Conformations of macromolecules and their complexes from heterogeneous datasets
2014
Roles of mutation and recombination in the evolution of protein thermodynamics
2002 StandoutNobel
Improved recognition of native-like protein structures using a family of designed sequences
2002 StandoutNobel
Interplay of structure and disorder in cochaperonin mobile loops.
1996
Trajectories of the ribosome as a Brownian nanomachine
2014 StandoutNobel
The molecular basis of eukaryotic transcription
2007 Nobel
Avermectin Biosynthesis
1997 StandoutNobel
Transfer RNA in the hybrid P/E state: Correlating molecular dynamics simulations with cryo-EM data
2007 StandoutNobel
Structural Perspective on Mutations Affecting the Function of Multisubunit RNA Polymerases
2006
Genetic interactions affecting touch sensitivity in Caenorhabditis elegans.
1996 StandoutNobel
Structure of Eukaryotic RNA Polymerases
2008
Subunit architecture of general transcription factor TFIIH
2012 Nobel
Complete, 12-subunit RNA polymerase II at 4.1-Å resolution: Implications for the initiation of transcription
2003 StandoutNobel
Participation of the Protein G o in Multiple Aspects of Behavior in C. elegans
1995 Science
Chromatin remodeling by nucleosome disassembly in vitro
2006 StandoutNobel
Distinct Mechanisms of Transcription Initiation by RNA Polymerases I and II
2018
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet
2011 StandoutNobel
Cryoelectron microscopy structures of the ribosome complex in intermediate states during tRNA translocation
2011 StandoutNobel
Structure of an RNA Polymerase II–TFIIB Complex and the Transcription Initiation Mechanism
2009 ScienceNobel
The process of mRNA–tRNA translocation
2007 StandoutNobel
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Association of the Mediator complex with enhancers of active genes
2003 StandoutNobel
Works of Ralph Davis being referenced
A Complex of the Srb8, -9, -10, and -11 Transcriptional Regulatory Proteins from Yeast
2002 StandoutNobel
Structural basis of eukaryotic gene transcription
2004 StandoutNobel
Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex
2016 Nobel
Formation and Fate of a Complete 31-Protein RNA Polymerase II Transcription Preinitiation Complex*
2013 Nobel
Quantitation of the RNA Polymerase II Transcription Machinery in Yeast
2001 StandoutNobel
Neuropeptides in the nematodeAscaris suum
1991
1H NMR Studies of Mouse Ribonucleotide Reductase: The R2 Protein Carboxyl-Terminal Tail, Essential for Subunit Interaction, Is Highly Flexible but becomes Rigid in the Presence of Protein R1
1994
Ab Initio Structure Determination from Electron Microscopic Images of Single Molecules Coexisting in Different Functional States
2010
Tfb6, a previously unidentified subunit of the general transcription factor TFIIH, facilitates dissociation of Ssl2 helicase after transcription initiation
2012 Nobel
Probing structure-function relationships of the DNA polymerase alpha-associated zinc-finger protein using computational approaches
1999 Nobel
Molecular architecture of the yeast Mediator complex
2015 Nobel
Structural Basis of Transcription: An RNA Polymerase II-TFIIB Cocrystal at 4.5 Angstroms
2004 StandoutScienceNobel
Neural control of behaviour in Ascaris
1985