Citation Impact
Citing Papers
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
2016 StandoutScienceNobel
CRISPR/Cas9 in Genome Editing and Beyond
2016
Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf1 (Cas12a)
2018
Single Reconstituted Neuronal SNARE Complexes Zipper in Three Distinct Stages
2012 StandoutScienceNobel
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9
2017 StandoutNobel
Programmable motion of DNA origami mechanisms
2015
Recruitment of CRISPR-Cas systems by Tn7-like transposons
2017
Cas3/I-C mediated target DNA recognition and cleavage during CRISPR interference are independent of the composition and architecture of Cascade surveillance complex
2020
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
Structural roles of guide RNAs in the nuclease activity of Cas9 endonuclease
2016
DNA Unwinding Is the Primary Determinant of CRISPR-Cas9 Activity
2018
Programmable RNA Shredding by the Type III-A CRISPR-Cas System of Streptococcus thermophilus
2014
DNA stretching induces Cas9 off-target activity
2019
A large size-selective DNA nanopore with sensing applications
2019
Structural basis for promiscuous PAM recognition in type I–E Cascade from E. coli
2016 Nature
Systematic analysis of CRISPR–Cas9 mismatch tolerance reveals low levels of off-target activity
2015
Torque Spectroscopy of DNA: Base-Pair Stability, Boundary Effects, Backbending, and Breathing Dynamics
2013
Two Distinct DNA Binding Modes Guide Dual Roles of a CRISPR-Cas Protein Complex
2015
Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage
2017 Nature
Recent developments in single-molecule DNA mechanics
2012
Expanding the Biologist’s Toolkit with CRISPR-Cas9
2015 StandoutNobel
DNA Nanodevices
2005
Gold rotor bead tracking for high-speed measurements of DNA twist, torque and extension
2014
RNA-based recognition and targeting: sowing the seeds of specificity
2017 StandoutNobel
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
DNA Targeting by a Minimal CRISPR RNA-Guided Cascade
2016 StandoutNobel
Self-assembled nanostructures based on DNA: towards the development of nanobiotechnology
2000
Multimodal Measurements of Single-Molecule Dynamics Using FluoRBT
2017
Macroscopic transport by synthetic molecular machines
2005
Spatiotemporal Control of Type III-A CRISPR-Cas Immunity: Coupling DNA Degradation with the Target RNA Recognition
2016
A Dynamic Search Process Underlies MicroRNA Targeting
2015
A decade of discovery: CRISPR functions and applications
2017
Mechanisms of improved specificity of engineered Cas9s revealed by single-molecule FRET analysis
2018
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
2017 StandoutNatureNobel
The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
2016 StandoutNatureNobel
CRISPR-Cas immunity in prokaryotes
2015 Nature
Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome
2015
CRISPR interference-based specific and efficient gene inactivation in the brain
2018
The structural biology of CRISPR-Cas systems
2015 StandoutNobel
Single-Stranded DNA Cleavage by Divergent CRISPR-Cas9 Enzymes
2015 StandoutNobel
A Biophysical Model of CRISPR/Cas9 Activity for Rational Design of Genome Editing and Gene Regulation
2016
Cas9 specifies functional viral targets during CRISPR–Cas adaptation
2015 Nature
A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture
2015
DNA and RNA interference mechanisms by CRISPR-Cas surveillance complexes
2015 StandoutNobel
Nucleic acid nanotechnology—towards Ångström-scale engineering
2004
Electrically driven directional motion of a four-wheeled molecule on a metal surface
2011 StandoutNatureNobel
Conformational control of DNA target cleavage by CRISPR–Cas9
2015 StandoutNatureNobel
Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas
2019
Molecular Machines Working on Surfaces and at Interfaces
2007
Integrated Nanoparticle–Biomolecule Hybrid Systems: Synthesis, Properties, and Applications
2004 Standout
DNA-binding-domain fusions enhance the targeting range and precision of Cas9
2015
Transposon-encoded CRISPR–Cas systems direct RNA-guided DNA integration
2019 Nature
Mechanism of CRISPR-RNA guided recognition of DNA targets inEscherichia coli
2015
Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex
2017
Selective Loading of Kinesin‐Powered Molecular Shuttles with Protein Cargo and its Application to Biosensing
2006
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
Repetitive DNA Reeling by the Cascade-Cas3 Complex in Nucleotide Unwinding Steps
2018
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation
2020 StandoutNobel
Shape‐Controlled Synthesis of Metal Nanocrystals: Simple Chemistry Meets Complex Physics?
2008 Standout
Lessons from Enzyme Kinetics Reveal Specificity Principles for RNA-Guided Nucleases in RNA Interference and CRISPR-Based Genome Editing
2017
Micelle and Vesicle Formation of Amphiphilic Nanoparticles
2009
Adaptation in CRISPR-Cas Systems
2016 StandoutNobel
Nanoparticles, Proteins, and Nucleic Acids: Biotechnology Meets Materials Science
2001 Standout
A practical guide to single-molecule FRET
2008 Standout
A Conserved Structural Chassis for Mounting Versatile CRISPR RNA-Guided Immune Responses
2015
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System
2017
Controlling protein assembly on inorganic crystals through designed protein interfaces
2019 StandoutNatureNobel
The Revolution Continues: Newly Discovered Systems Expand the CRISPR-Cas Toolkit
2017
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System
2015 StandoutNobel
The RSC chromatin remodelling ATPase translocates DNA with high force and small step size
2011
Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9
2016 StandoutNobel
Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage
2015
Genome-editing revolution: My whirlwind year with CRISPR
2015 StandoutNatureNobel
The Bacterial Origins of the CRISPR Genome-Editing Revolution
2015
A prudent path forward for genomic engineering and germline gene modification
2015 StandoutScienceNobel
Millisecond Curing Time of a Molecular Adhesive Causes Velocity-Dependent Cargo-Loading of Molecular Shuttles
2009
A Cas9–guide RNA complex preorganized for target DNA recognition
2015 StandoutScienceNobel
Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems
2016 Science
Dynamics of CRISPR-Cas9 genome interrogation in living cells
2015 StandoutScienceNobel
DNA-Templated Ag Nanocluster Formation
2004
New Photolabile Functional Polymers for Patterning onto Gold Obtained by Click Chemistry
2007
From DNA to transistors
2004
DNA-based plasmonic nanostructures
2015
CRISPR-Cas: New Tools for Genetic Manipulations from Bacterial Immunity Systems
2015
Torque measurements reveal sequence-specific cooperative transitions in supercoiled DNA
2012
Systematic discovery of natural CRISPR-Cas12a inhibitors
2018 StandoutScienceNobel
Crystal structure of a CRISPR RNA–guided surveillance complex bound to a ssDNA target
2014 Science
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning
2015 StandoutScienceNobel
The chemistry of Cas9 and its CRISPR colleagues
2017 StandoutNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
CRISPR-Cas9 nuclear dynamics and target recognition in living cells
2016
CRISPR-CasΦ from huge phages is a hypercompact genome editor
2020 StandoutScienceNobel
Structure and Mechanism of Helicases and Nucleic Acid Translocases
2007
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
RNA-dependent RNA targeting by CRISPR-Cas9
2018 StandoutNobel
Structure basis for RNA-guided DNA degradation by Cascade and Cas3
2018 Science
Target Specificity of Cas9 Nuclease via DNA Rearrangement Regulated by the REC2 Domain
2018
Artificial Molecular Machines
2015 Standout
Structure Reveals a Mechanism of CRISPR-RNA-Guided Nuclease Recruitment and Anti-CRISPR Viral Mimicry
2019
Biotemplated Nanopatterning of Planar Surfaces with Molecular Motors
2006
Recent Advances in the Liquid-Phase Syntheses of Inorganic Nanoparticles
2004 Standout
Cas3 Protein—A Review of a Multi-Tasking Machine
2020
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Motor Proteins at Work for Nanotechnology
2007 Science
Directed DNA Metallization
2006
PAM identification by CRISPR-Cas effector complexes: diversified mechanisms and structures
2018
One‐Dimensional Assemblies of Nanoparticles: Preparation, Properties, and Promise
2005
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
The Effect of DNA Topology on Observed Rates of R-Loop Formation and DNA Strand Cleavage by CRISPR Cas12a
2019
Understanding the Molecular Mechanisms of the CRISPR Toolbox Using Single Molecule Approaches
2018
Self-Assembly of Colloidal Nanocrystals: From Intricate Structures to Functional Materials
2016 Standout
Growth of Platinum Clusters via Addition of Pt(II) Complexes: A First Principles Investigation
2003
Works of Ralf Seidel being referenced
Directional R-Loop Formation by the CRISPR-Cas Surveillance Complex Cascade Provides Efficient Off-Target Site Rejection
2015
Single-Molecule Insight Into Target Recognition by CRISPR–Cas Complexes
2016
When a helicase is not a helicase: dsDNA tracking by the motor protein EcoR124I
2006
Torsional Stiffness of Single Superparamagnetic Microspheres in an External Magnetic Field
2009
Amphipathic DNA Origami Nanoparticles to Scaffold and Deform Lipid Membrane Vesicles
2015
Direct Mechanical Measurements Reveal the Material Properties of Three-Dimensional DNA Origami
2011
Single-molecule studies of nucleic acid motors
2007
Real-time observation of DNA translocation by the type I restriction modification enzyme EcoR124I
2004
DNA–DNA Interactions in Tight Supercoils Are Described by a Small Effective Charge Density
2010
Energetics at the DNA Supercoiling Transition
2010
Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes
2014
Scanning force microscopy of DNA metallization
2002
Shape-Controlled Synthesis of Gold Nanostructures Using DNA Origami Molds
2014
Stretching and Transporting DNA Molecules Using Motor Proteins
2003
Site-specific binding and stretching of DNA molecules at UV-light-patterned aminoterpolymer films
2004
Simultaneous Single-Molecule Force and Fluorescence Sampling of DNA Nanostructure Conformations Using Magnetic Tweezers
2015
Primed CRISPR adaptation in Escherichia coli cells does not depend on conformational changes in the Cascade effector complex detected in Vitro
2018
Nucleation of platinum clusters on biopolymers: a first principles study of the molecular mechanisms
2003
Nanoscale Palladium Metallization of DNA
2000
DNA as a Selective Metallization Template
2002