Citation Impact
Citing Papers
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
2012 StandoutScience
Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity
2013 StandoutNobel
LapD is a bis-(3′,5′)-cyclic dimeric GMP-binding protein that regulates surface attachment by Pseudomonas fluorescens Pf0–1
2009
Asymmetrical Distribution of the Second Messenger c-di-GMP upon Bacterial Cell Division
2010 Science
Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
2012 StandoutScience
The Cyclic Nucleotide Monophosphate Domain of Xanthomonas campestris Global Regulator Clp Defines a New Class of Cyclic Di-GMP Effectors
2009
Cell–cell signal-dependent dynamic interactions between HD-GYP and GGDEF domain proteins mediate virulence in Xanthomonas campestris
2010
A chemosensory system that regulates biofilm formation through modulation of cyclic diguanylate levels
2005
A Genome-Wide Screen Identifies Genes in Rhizosphere-Associated Pseudomonas Required to Evade Plant Defenses
2018
The Pseudomonas aeruginosa accessory genome elements influence virulence towards Caenorhabditis elegans
2019 StandoutNobel
PilZ Domain Proteins Bind Cyclic Diguanylate and Regulate Diverse Processes in Vibrio cholerae
2007
Structure of the Cytoplasmic Region of PelD, a Degenerate Diguanylate Cyclase Receptor That Regulates Exopolysaccharide Production in Pseudomonas aeruginosa
2012
YybT Is a Signaling Protein That Contains a Cyclic Dinucleotide Phosphodiesterase Domain and a GGDEF Domain with ATPase Activity
2009
UV Light Potentiates STING (Stimulator of Interferon Genes)-dependent Innate Immune Signaling through Deregulation of ULK1 (Unc51-like Kinase 1)
2015 StandoutNobel
Solution Structure of the PilZ Domain Protein PA4608 Complex with Cyclic di-GMP Identifies Charge Clustering as Molecular Readout
2011
Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3′-5′)-cyclic-GMP in virulence
2006
Targeting microbial biofilms: current and prospective therapeutic strategies
2017 Standout
Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding
2012
Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2′,3′ cGAMP Signaling
2015 StandoutNobel
Role of the GGDEF protein family in Salmonella cellulose biosynthesis and biofilm formation
2004
The structural basis of cyclic diguanylate signal transduction by PilZ domains
2007
The FleQ protein from Pseudomonas aeruginosa functions as both a repressor and an activator to control gene expression from the pel operon promoter in response to c-di-GMP
2012
YfiBNR Mediates Cyclic di-GMP Dependent Small Colony Variant Formation and Persistence in Pseudomonas aeruginosa
2010
Genome-wide Transcriptional Profile of Escherichia coli in Response to High Levels of the Second Messenger 3′,5′-Cyclic Diguanylic Acid
2006
Second messenger-mediated spatiotemporal control of protein degradation regulates bacterial cell cycle progression
2009
Regulatory Cohesion of Cell Cycle and Cell Differentiation through Interlinked Phosphorylation and Second Messenger Networks
2011
cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
2013 StandoutNature
The potential of 3′,5′-cyclic diguanylic acid (c-di-GMP) as an effective vaccine adjuvant
2010
Regulation and function of the cGAS–STING pathway of cytosolic DNA sensing
2016 Standout
A chemical proteomics approach to identify c-di-GMP binding proteins in Pseudomonas aeruginosa
2011
Histidine kinases and response regulators in networks
2011
The Atypical Two-component Sensor Kinase Lpl0330 from Legionella pneumophila Controls the Bifunctional Diguanylate Cyclase-Phosphodiesterase Lpl0329 to Modulate Bis-(3′-5′)-cyclic Dimeric GMP Synthesis
2011
Structural characterization reveals that a PilZ domain protein undergoes substantial conformational change upon binding to cyclic dimeric guanosine monophosphate
2010
A Polymeric Protein Anchors the Chromosomal Origin/ParB Complex at a Bacterial Cell Pole
2008 StandoutNobel
Ginger Extract Inhibits Biofilm Formation by Pseudomonas aeruginosa PA14
2013
The role of PilZ domain proteins in the virulence of Xanthomonas campestris pv. campestris
2008
A Novel Tetrameric PilZ Domain Structure from Xanthomonads
2011
Biofilms: the matrix revisited
2004 Standout
Identification of a novel regulatory protein (CsrD) that targets the global regulatory RNAs CsrB and CsrC for degradation by RNase E
2006
Cellulose nanomaterials review: structure, properties and nanocomposites
2011 Standout
Switching Pyridine Nucleotide Specificity in P450 BM3
2005
Light‐induced alteration of c‐di‐GMP level controls motility of Synechocystis sp. PCC 6803
2012
Bacterial signal transduction network in a genomic perspective †
2004
Plant–microbiome interactions: from community assembly to plant health
2020 Standout
Methanogenic archaea: ecologically relevant differences in energy conservation
2008 Standout
Sensing the messenger: The diverse ways that bacteria signal through c‐di‐GMP
2012
Improved product‐per‐glucose yields in P450‐dependent propane biotransformations using engineered Escherichia coli
2010 StandoutNobel
Coordinated Cyclic-Di-GMP Repression of Salmonella Motility through YcgR and Cellulose
2012
The BLUF-EAL protein YcgF acts as a direct anti-repressor in a blue-light response of Escherichia coli
2009
Enzymatic synthesis of c-di-GMP using a thermophilic diguanylate cyclase
2009
Quorum sensing signal–response systems in Gram-negative bacteria
2016 Standout
Should we stay or should we go: mechanisms and ecological consequences for biofilm dispersal
2011
Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity
2014 StandoutNobel
Systematic analysis of cyclic di‐GMP signalling enzymes and their role in biofilm formation and virulence in Yersinia pestis
2010
You’ve come a long way: c-di-GMP signaling
2012
The second messenger bis‐(3′‐5′)‐cyclic‐GMP and its PilZ domain‐containing receptor Alg44 are required for alginate biosynthesis in Pseudomonas aeruginosa
2007
Cyclic di-guanosine-monophosphate comes of age: a novel secondary messenger involved in modulating cell surface structures in bacteria?
2004
Growth of the plant cell wall
2005 Standout
Setting the pace: mechanisms tying Caulobacter cell-cycle progression to macroscopic cellular events
2004
The structure and inhibition of a GGDEF diguanylate cyclase complexed with (c-di-GMP)2at the active site
2011
c-di-GMP Turn-Over in Clostridium difficile Is Controlled by a Plethora of Diguanylate Cyclases and Phosphodiesterases
2011
Sequential treatment for Helicobacter pylori does not share the risk factors of triple therapy failure
2004
Bacterial nucleotide-based second messengers
2009
Cellulose Biosynthesis: Current Views and Evolving Concepts
2005
Identification, Activity and Disulfide Connectivity of C-di-GMP Regulating Proteins in Mycobacterium tuberculosis
2010
STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
2014 Standout
Biofilm formation at the air–liquid interface by the Pseudomonas fluorescens SBW25 wrinkly spreader requires an acetylated form of cellulose
2003
Comparative genomics of cyclic-di-GMP signalling in bacteria: post-translational regulation and catalytic activity
2010
A novel capture compound for the identification and analysis of cyclic di-GMP binding proteins
2012
Genetic analysis of two phosphodiesterases reveals cyclic diguanylate regulation of virulence factors in Dickeya dadantii
2010
Identification and Characterization of a Cyclic di-GMP-specific Phosphodiesterase and Its Allosteric Control by GTP
2005
Genes essential for morphological development and antibiotic production in Streptomyces coelicolor are targets of BldD during vegetative growth
2010
C‐di‐GMP: the dawning of a novel bacterial signalling system
2005
The RNA binding protein CsrA controls cyclic di‐GMP metabolism by directly regulating the expression of GGDEF proteins
2008
Determinants for the Activation and Autoinhibition of the Diguanylate Cyclase Response Regulator WspR
2009
Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING
2012
A cyclic‐di‐GMP receptor required for bacterial exopolysaccharide production
2007
Evidence for Cyclic Di-GMP-Mediated Signaling in Bacillus subtilis
2012
Large-Scale Production of the Immunomodulator c-di-GMP from GMP and ATP by an Enzymatic Cascade
2011
Inverse regulatory coordination of motility and curli-mediated adhesion in Escherichia coli
2008
Structures, mechanism, regulation and evolution of class III nucleotidyl cyclases
2006
Cytokinesis Monitoring during Development
2004
Diversity of structure and function of response regulator output domains
2010
A field guide to bacterial swarming motility
2010 Standout
Biofilms: an emergent form of bacterial life
2016 Standout
Structural Analysis of the GGDEF-EAL Domain-Containing c-di-GMP Receptor FimX
2009
Insights into Yersinia pestis biofilm development: topology and co‐interaction of Hms inner membrane proteins involved in exopolysaccharide production
2008
Structural Biochemistry of a Bacterial Checkpoint Protein Reveals Diadenylate Cyclase Activity Regulated by DNA Recombination Intermediates
2008
The biofilm matrix
2010 Standout
The HD‐GYP domain of RpfG mediates a direct linkage between the Rpf quorum‐sensing pathway and a subset of diguanylate cyclase proteins in the phytopathogen Xanthomonas axonopodis pv citri
2006
Cyclic di-GMP is Essential for the Survival of the Lyme Disease Spirochete in Ticks
2011
Bacterial Birth Scar Proteins Mark Future Flagellum Assembly Site
2006
Structural Insights into the Regulatory Mechanism of the Response Regulator RocR from Pseudomonas aeruginosa in Cyclic Di-GMP Signaling
2012
The YfiBNR Signal Transduction Mechanism Reveals Novel Targets for the Evolution of Persistent Pseudomonas aeruginosa in Cystic Fibrosis Airways
2012
Chemotherapeutics: antibiotics and other antimicrobials
2004
Cyclic Di-GMP Phosphodiesterases RmdA and RmdB Are Involved in Regulating Colony Morphology and Development in Streptomyces coelicolor
2012
Genomic and Functional Characterization of Enterococcus faecalis Isolates Recovered From the International Space Station and Their Potential for Pathogenicity
2021 StandoutNobel
Aminoglycoside antibiotics induce bacterial biofilm formation
2005 Nature
An Unorthodox Bacteriophytochrome from Rhodobacter sphaeroides Involved in Turnover of the Second Messenger c-di-GMP
2006
The PilZ Domain Is a Receptor for the Second Messenger c-di-GMP
2006
XC1028 from Xanthomonas campestris adopts a PilZ domain‐like structure without a c‐di‐GMP switch
2008
Cell-cycle progression and the generation of asymmetry in Caulobacter crescentus
2004
A census of membrane-bound and intracellular signal transduction proteins in bacteria: Bacterial IQ, extroverts and introverts
2005
Cyclic di‐GMP, an established secondary messenger still speeding up
2011
LtmA, a novel cyclic di-GMP-responsive activator, broadly regulates the expression of lipid transport and metabolism genes in Mycobacterium smegmatis
2012
The bacterial second messenger c-di-GMP: mechanisms of signalling
2011
Tyrosine phosphatase TpbA controls rugose colony formation in Pseudomonas aeruginosa by dephosphorylating diguanylate cyclase TpbB
2010
Virulence strategies for infecting phagocytes deduced from the in vivo transcriptional program of Legionella pneumophila
2006
Nitric Oxide Modulates Bacterial Biofilm Formation through a Multicomponent Cyclic-di-GMP Signaling Network
2012
A multi‐repeat adhesin of the phytopathogen, Pectobacterium atrosepticum, is secreted by a Type I pathway and is subject to complex regulation involving a non‐canonical diguanylate cyclase
2011
Prevalence of Antibiotic Resistance in Helicobacter pylori: A Systematic Review and Meta-analysis in World Health Organization Regions
2018 Standout
Automated Protein Structure Modeling with SWISS-MODEL Workspace and the Protein Model Portal
2011
Two-Component Signal Transduction Pathways Regulating Growth and Cell Cycle Progression in a Bacterium: A System-Level Analysis
2005
A review of the biomaterials technologies for infection-resistant surfaces
2013 Standout
The complexity of the ‘simple’ two-component system KdpD/KdpE inEscherichia coli
2010
The EAL Domain Protein VieA Is a Cyclic Diguanylate Phosphodiesterase
2005
Globins Synthesize the Second Messenger Bis-(3′–5′)-Cyclic Diguanosine Monophosphate in Bacteria
2009
A c-di-GMP Effector System Controls Cell Adhesion by Inside-Out Signaling and Surface Protein Cleavage
2011
Characterization of the rdar morphotype, a multicellular behaviour in Enterobacteriaceae
2005
H pylori antibiotic resistance: prevalence, importance, and advances in testing
2004 Standout
Pseudomonas aeruginosa cupA ‐encoded fimbriae expression is regulated by a GGDEF and EAL domain‐dependent modulation of the intracellular level of cyclic diguanylate
2007
Quantitative determination of cyclic diguanosine monophosphate concentrations in nucleotide extracts of bacteria by matrix-assisted laser desorption/ionization–time-of-flight mass spectrometry
2008
Implant infections: adhesion, biofilm formation and immune evasion
2018 Standout
The phosphodiesterase activity of the HmsP EAL domain is required for negative regulation of biofilm formation inYersinia pestis
2005
Structural Basis for c-di-GMP-Mediated Inside-Out Signaling Controlling Periplasmic Proteolysis
2011
Cyclic‐di‐GMP‐mediated signalling within the σS network of Escherichia coli
2006
A liquid chromatography-coupled tandem mass spectrometry method for quantitation of cyclic di-guanosine monophosphate
2010
BcsQ is an essential component of the Escherichia coli cellulose biosynthesis apparatus that localizes at the bacterial cell pole
2009
Periodontal diseases
2005 Standout
Structure of PP4397 Reveals the Molecular Basis for Different c-di-GMP Binding Modes by Pilz Domain Proteins
2010
Biomaterials immobilized with chitosan for rechargeable antimicrobial drug delivery
2012
DUFs: families in search of function
2010
Phosphate‐dependent modulation of c‐di‐GMP levels regulates Pseudomonas fluorescens Pf0‐1 biofilm formation by controlling secretion of the adhesin LapA
2006
Cellular Levels and Binding of c-di-GMP Control Subcellular Localization and Activity of the Vibrio cholerae Transcriptional Regulator VpsT
2012
Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation
2020 StandoutNobel
An EAL domain protein and cyclic AMP contribute to the interaction between the two quorum sensing systems in Escherichia coli
2008
The orphan histidine protein kinase SgmT is a c‐di‐GMP receptor and regulates composition of the extracellular matrix together with the orphan DNA binding response regulator DigR in Myxococcus xanthus
2012
Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase
2013
Discrete Cyclic di-GMP-Dependent Control of Bacterial Predation versus Axenic Growth in Bdellovibrio bacteriovorus
2012
The c-di-GMP Binding Protein YcgR Controls Flagellar Motor Direction and Speed to Affect Chemotaxis by a “Backstop Brake” Mechanism
2010
A spindle-like apparatus guides bacterial chromosome segregation
2010 StandoutNobel
OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids
2014
Urinary tract infections: epidemiology, mechanisms of infection and treatment options
2015 Standout
Subcellular location characteristics of the Pseudomonas aeruginosa GGDEF protein, WspR, indicate that it produces cyclic‐di‐GMP in response to growth on surfaces
2007
The Pfam protein families database
2011 Standout
Complex c-di-GMP Signaling Networks Mediate Transition between Virulence Properties and Biofilm Formation in Salmonella enterica Serovar Typhimurium
2011
Binding of Cyclic Diguanylate in the Non-catalytic EAL Domain of FimX Induces a Long-range Conformational Change
2010
Cyclic diguanylate (c‐di‐GMP) regulates Vibrio cholerae biofilm formation
2004
Structural and mechanistic determinants of c-di-GMP signalling
2009
Complex regulatory network encompassing the Csr, c‐di‐GMP and motility systems of Salmonella Typhimurium
2009
Analysis of FimX, a phosphodiesterase that governs twitching motility in Pseudomonas aeruginosa
2006
HD‐GYP domain proteins regulate biofilm formation and virulence in Pseudomonas aeruginosa
2008
Drug resistance pattern and clonality in H. pylori strains
2009
A glutamate‐alanine‐leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP
2005
Principles of c-di-GMP signalling in bacteria
2009
A crystallographic study of Cys69Ala flavodoxin II from Azotobacter vinelandii: Structural determinants of redox potential
2005
Allosteric activation of exopolysaccharide synthesis through cyclic di‐GMP‐stimulated protein–protein interaction
2012
Design and Synthesis ofbis-carbamate Analogs of Cyclicbis-(3′-5′)-Diguanylic Acid (c-di-GMP) and the Acyclic Dimer PGPG
2008
Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report
2006 Standout
Cyclic di-GMP as a second messenger
2006
Co‐regulation of Xanthomonas campestris virulence by quorum sensing and a novel two‐component regulatory system RavS/RavR
2009
Crystal Structures of YkuI and Its Complex with Second Messenger Cyclic Di-GMP Suggest Catalytic Mechanism of Phosphodiester Bond Cleavage by EAL Domains
2009
Structural basis of ligand binding by a c-di-GMP riboswitch
2009
The prokaryote messenger c-di-GMP triggers stalk cell differentiation in Dictyostelium
2012 Nature
Structural Insight into the Mechanism of c-di-GMP Hydrolysis by EAL Domain Phosphodiesterases
2010
Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity
2013 StandoutNobel
Penicillin-binding proteins and β-lactam resistance
2008
PILZ Protein Structure and Interactions with PILB and the FIMX EAL Domain: Implications for Control of Type IV Pilus Biogenesis
2009
Systematic Analysis of Diguanylate Cyclases That Promote Biofilm Formation by Pseudomonas fluorescens Pf0-1
2011
Cyclic Diguanylate Inversely Regulates Motility and Aggregation in Clostridium difficile
2012
An Oxygen-Sensing Diguanylate Cyclase and Phosphodiesterase Couple for c-di-GMP Control
2009
Oligomer Formation of the Bacterial Second Messenger c-di-GMP: Reaction Rates and Equilibrium Constants Indicate a Monomeric State at Physiological Concentrations
2011
BifA, a Cyclic-Di-GMP Phosphodiesterase, Inversely Regulates Biofilm Formation and Swarming Motility byPseudomonas aeruginosaPA14
2007
DgrA is a member of a new family of cyclic diguanosine monophosphate receptors and controls flagellar motor function in Caulobacter crescentus
2007
Quorum Sensing Controls Biofilm Formation in Vibrio cholerae through Modulation of Cyclic Di-GMP Levels and Repression of vpsT
2008
The Ubiquitous Protein Domain EAL Is a Cyclic Diguanylate-Specific Phosphodiesterase: Enzymatically Active and Inactive EAL Domains
2005
Control of Formation and Cellular Detachment from Shewanella oneidensis MR-1 Biofilms by Cyclic di-GMP
2006
Role of Cyclic Di-GMP during El Tor Biotype Vibrio cholerae Infection: Characterization of the In Vivo-Induced Cyclic Di-GMP Phosphodiesterase CdpA
2008
c-di-GMP (3′-5′-Cyclic Diguanylic Acid) Inhibits Staphylococcus aureus Cell-Cell Interactions and Biofilm Formation
2005
MucR, a Novel Membrane-Associated Regulator of Alginate Biosynthesis inPseudomonas aeruginosa
2008
The structure–function relationship of WspR, a Pseudomonas fluorescens response regulator with a GGDEF output domain
2007
The Pfam protein families database in 2019
2018 Standout
The diguanylate cyclase YddV controls production of the exopolysaccharide poly-N-acetylglucosamine (PNAG) through regulation of the PNAG biosynthetic pgaABCD operon
2010
A Staphylococcal GGDEF Domain Protein Regulates Biofilm Formation Independently of Cyclic Dimeric GMP
2008
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
2016 StandoutNatureNobel
Bacterial scaffold directs pole-specific centromere segregation
2014 StandoutNobel
Nucleotide, c-di-GMP, c-di-AMP, cGMP, cAMP, (p)ppGpp signaling in bacteria and implications in pathogenesis
2012
FliL is essential for swarming: motor rotation in absence of FliL fractures the flagellar rod in swarmer cells of Salmonella enterica
2008
Identification and Characterization of CdgB, a Diguanylate Cyclase Involved in Developmental Processes in Streptomyces coelicolor
2011
Role of EAL-Containing Proteins in Multicellular Behavior ofSalmonella entericaSerovar Typhimurium
2007
Cyclic Dimeric GMP Signaling Regulates Intracellular Aggregation, Sessility, and Growth of Ehrlichia chaffeensis
2011
Hierarchical involvement of various GGDEF domain proteins in rdar morphotype development of Salmonella enterica serovar Typhimurium
2006
Minor Pilins of the Type IV Pilus System Participate in the Negative Regulation of Swarming Motility
2012
A Flavin Cofactor-Binding PAS Domain Regulates c-di-GMP Synthesis in AxDGC2 from Acetobacter xylinum
2009
Antimicrobial Susceptibility and Resistance Patterns among Helicobacter pylori Strains from The Gambia, West Africa
2012
GGDEF and EAL domains inversely regulate cyclic di‐GMP levels and transition from sessility to motility
2004
SWISS-MODEL: homology modelling of protein structures and complexes
2018 Standout
High-Level β-Lactam Resistance Associated with Acquired Multidrug Resistance in Helicobacter pylori
2003
The Cyclic-di-GMP Phosphodiesterase BinA Negatively Regulates Cellulose-Containing Biofilms inVibrio fischeri
2010
Quantification of high-specificity cyclic diguanylate signaling
2012
Cyclic Diguanylate Is a Ubiquitous Signaling Molecule in Bacteria: Insights into Biochemistry of the GGDEF Protein Domain
2005
Cyclic di-GMP Signaling Regulates Invasion by Ehrlichia chaffeensis of Human Monocytes
2010
The Phosphodiesterase DipA (PA5017) Is Essential for Pseudomonas aeruginosa Biofilm Dispersion
2012
SadC Reciprocally Influences Biofilm Formation and Swarming Motility via Modulation of Exopolysaccharide Production and Flagellar Function
2007
Cyclic‐diGMP signal transduction systems in Vibrio cholerae: modulation of rugosity and biofilm formation
2006
Identification of FleQ from Pseudomonas aeruginosa as a c‐di‐GMP‐responsive transcription factor
2008
Genetic reductionist approach for dissecting individual roles of GGDEF proteins within the c-di-GMP signaling network in Salmonella
2009
Bacterial Resistance to β-Lactam Antibiotics: Compelling Opportunism, Compelling Opportunity
2005 Standout
Cyclic-di-GMP Regulates Extracellular Polysaccharide Production, Biofilm Formation, and Rugose Colony Development by Vibrio vulnificus
2008
Mechanisms of Cyclic-di-GMP Signaling in Bacteria
2006
A bacterial Argonaute with noncanonical guide RNA specificity
2016 StandoutNobel
Modulation of Pseudomonas aeruginosa Biofilm Dispersal by a Cyclic-Di-GMP Phosphodiesterase with a Putative Hypoxia-Sensing Domain
2010
Adaptive Divergence in Experimental Populations ofPseudomonas fluorescens. II. Role of the GGDEF Regulator WspR in Evolution and Development of the Wrinkly Spreader Phenotype
2006
Three-dimensional superresolution colocalization of intracellular protein superstructures and the cell surface in live Caulobacter crescentus
2011 StandoutNobel
Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase
2013 StandoutNobel
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Escherichia coli K-12 YfgF is an anaerobic cyclic di-GMP phosphodiesterase with roles in cell surface remodelling and the oxidative stress response
2010
Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger
2013 Standout
The Anaplasma phagocytophilum PleC Histidine Kinase and PleD Diguanylate Cyclase Two-Component System and Role of Cyclic Di-GMP in Host Cell Infection
2008
Three Decades of β-Lactamase Inhibitors
2010 Standout
CdpA Is a Burkholderia pseudomallei Cyclic di-GMP Phosphodiesterase Involved in Autoaggregation, Flagellum Synthesis, Motility, Biofilm Formation, Cell Invasion, and Cytotoxicity
2010
Cyclic Diguanylate Signaling Proteins Control Intracellular Growth of Legionella pneumophila
2011
Small-Molecule Labeling of Live Cell Surfaces for Three-Dimensional Super-Resolution Microscopy
2014 StandoutNobel
Signals, Regulatory Networks, and Materials That Build and Break Bacterial Biofilms
2009
Getting in the Loop: Regulation of Development inCaulobacter crescentus
2010
Type IV Pilus Assembly in Pseudomonas aeruginosa over a Broad Range of Cyclic di-GMP Concentrations
2012
Identification of Small Molecules That Antagonize Diguanylate Cyclase Enzymes To Inhibit Biofilm Formation
2012
Roles of Cyclic Diguanylate in the Regulation of Bacterial Pathogenesis
2007
Riboswitches in Eubacteria Sense the Second Messenger Cyclic Di-GMP
2008 Science
Regulation of biofilm formation in P seudomonas and B urkholderia species
2014
A Role for the EAL-Like Protein STM1344 in Regulation of CsgD Expression and Motility inSalmonella entericaSerovar Typhimurium
2009
Smooth to rugose phase variation in Vibrio cholerae can be mediated by a single nucleotide change that targets c‐di‐GMP signalling pathway
2006
The Structure of an Unconventional HD-GYP Protein from Bdellovibrio Reveals the Roles of Conserved Residues in this Class of Cyclic-di-GMP Phosphodiesterases
2011
A full-length bifunctional protein involved in c-di-GMP turnover is required for long-term survival under nutrient starvation in Mycobacterium smegmatis
2012
The Mononuclear Molybdenum Enzymes
2014 Standout
Cyclic di‐GMP signalling in the virulence and environmental adaptation of Xanthomonas campestris
2006
Structural basis of differential ligand recognition by two classes of bis-(3′-5′)-cyclic dimeric guanosine monophosphate-binding riboswitches
2011
Cyclic Di-GMP Stimulates Biofilm Formation and Inhibits Virulence of Francisella novicida
2012
Gene expression patterns and differential input into curli fimbriae regulation of all GGDEF/EAL domain proteins in Escherichia coli
2009
Cyclic di-GMP as a bacterial second messenger
2004
Cyclic di-nucleotide signaling enters the eukaryote domain
2013
Identification and Characterization of Cyclic Diguanylate Signaling Systems Controlling Rugosity in Vibrio cholerae
2008
Vibrio parahaemolyticusScrC Modulates Cyclic Dimeric GMP Regulation of Gene Expression Relevant to Growth on Surfaces
2007
c-di-GMP Displays A Monovalent Metal Ion-Dependent Polymorphism
2004
Distinct Constrictive Processes, Separated in Time and Space, DivideCaulobacterInner and Outer Membranes
2005 StandoutNobel
The Anabaena sp. Strain PCC 7120 Gene all2874 Encodes a Diguanylate Cyclase and Is Required for Normal Heterocyst Development under High-Light Growth Conditions
2008
Specific Control of Pseudomonas aeruginosa Surface-Associated Behaviors by Two c-di-GMP Diguanylate Cyclases
2010
Prevailing Concepts of c-di-GMP Signaling
2009
In Silico Discovery and In Vitro Validation of Catechol-Containing Sulfonohydrazide Compounds as Potent Inhibitors of the Diguanylate Cyclase PleD
2015
The response threshold of S almonellaPilZ GMP
2012
PilZ domain is part of the bacterial c-di-GMP binding protein
2005
Great Times for Small Molecules: c-di-AMP, a Second Messenger Candidate in Bacteria and Archaea
2008
Structural Classification of Bacterial Response Regulators: Diversity of Output Domains and Domain Combinations
2006
Characterization of starvation‐induced dispersion in Pseudomonas putida biofilms
2005
Antimicrobial Resistance in ESKAPE Pathogens
2020 Standout
Get the Message Out: Cyclic-Di-GMP Regulates Multiple Levels of Flagellum-Based Motility
2007
Bacterial Small-Molecule Signaling Pathways
2006 Science
N-Acetylglucosamine-dependent biofilm formation in Pectobacterium atrosepticum is cryptic and activated by elevated c-di-GMP levels
2011
Purification and Characterization of a Type III Photolyase from Caulobacter crescentus
2008 StandoutNobel
A CsgD-Independent Pathway for Cellulose Production and Biofilm Formation inEscherichia coli
2006
ScrG, a GGDEF-EAL Protein, Participates in Regulating Swarming and Sticking inVibrio parahaemolyticus
2007
Brucella melitensis Cyclic di-GMP Phosphodiesterase BpdA Controls Expression of Flagellar Genes
2011
Systems Biology of Caulobacter
2007
Works of Ralf Paul being referenced
Crystal structure of oxidized flavodoxin, an essential protein in Helicobacter pylori
2002
Allosteric Regulation of Histidine Kinases by Their Cognate Response Regulator Determines Cell Fate
2008
Structure of BeF3−-Modified Response Regulator PleD: Implications for Diguanylate Cyclase Activation, Catalysis, and Feedback Inhibition
2007
Allosteric Control of Cyclic di-GMP Signaling
2006
Cell cycle-dependent dynamic localization of a bacterial response regulator with a novel di-guanylate cyclase output domain
2004
Role of the GGDEF regulator PleD in polar development of Caulobacter crescentus
2003
Activation of the Diguanylate Cyclase PleD by Phosphorylation-mediated Dimerization
2007
Allosteric Control of Cyclic di-GMP Signaling
2006
Structural basis of activity and allosteric control of diguanylate cyclase
2004
Mutations of the Helicobacter pylori Genes rdxA and pbp1 Cause Resistance against Metronidazole and Amoxicillin
2001