Citation Impact
Citing Papers
A polybasic domain in aPKC mediates Par6-dependent control of membrane targeting and kinase activity
2020
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
Stem Cell–Derived Culture Models of Hepatitis E Virus Infection
2018 StandoutNobel
Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication
2015
Targeting bile-acid signalling for metabolic diseases
2008
Peptide Nanofiber Hydrogel Induces Formation of Bile Canaliculi Structures in Three-Dimensional Hepatic Cell Culture
2012
Bile acid transporters
2009
Multidrug resistance in cancer: role of ATP–dependent transporters
2002 Standout
Bile acid receptors as targets for the treatment of dyslipidemia and cardiovascular disease
2012
Pan-Genotype Hepatitis E Virus Replication in Stem Cell–Derived Hepatocellular Systems
2017 StandoutNobel
Orantinib versus placebo combined with transcatheter arterial chemoembolisation in patients with unresectable hepatocellular carcinoma (ORIENTAL): a randomised, double-blind, placebo-controlled, multicentre, phase 3 study
2017
An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis
2000
Pleiotropic Roles of Bile Acids in Metabolism
2013
De Novo Macrocyclic Peptide Inhibitors of Hepatitis B Virus Cellular Entry
2018
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Liver fibrosis
2005 Standout
The Diversity of Volume Regulatory Mechanisms
1998
Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance
1999
A robust cell culture system supporting the complete life cycle of hepatitis B virus
2017 StandoutNobel
The Influence of Macromolecular Crowding and Macromolecular Confinement on Biochemical Reactions in Physiological Media
2001 Standout
Effects of P‐glycoprotein expression on cyclic AMP and volume‐activated ion fluxes and conductances in HT‐29 colon adenocarcinoma cells
1994
Calcium is not involved in the cAMP-mediated stimulation of Cl? conductance in the apical membrane of Necturus gallbladder epithelium
1995
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Macrophages and HIV-1: dangerous liaisons
2004
The cAMP-regulated and 293B-inhibited K+ conductance of rat colonic crypt base cells
1996
Management of NAFLD: a stage-based approach
2016
Asian‐Pacific consensus statement on the management of chronic hepatitis B: An update*
2003
Lipopolysaccharide‐induced tyrosine nitration and inactivation of hepatic glutamine synthetase in the rat† ‡
2005
Spinoculation Enhances HBV Infection in NTCP-Reconstituted Hepatocytes
2015
Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock
2002 Standout
Scleroderma
2009 Standout
Differential effects of tamoxifen and I? on three distinguishable chloride currents activated in T84 intestinal cells
1993
Lamivudine for Patients with Chronic Hepatitis B and Advanced Liver Disease
2004 Standout
Inflammatory cytokines induce protein tyrosine nitration in rat astrocytes
2006
Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis
2015 Standout
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Involvement of NADPH Oxidase Isoforms and Src Family Kinases in CD95-dependent Hepatocyte Apoptosis
2005
Increase in cytosolic Ca2+ regulates exocytosis and Cl? conductance in HT29 cells
1993
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
Schistosomiasis
2018 Standout
Lipopolysaccharides induced increases in Fas ligand expression by Kupffer cells via mechanisms dependent on reactive oxygen species
2004
Diet–microbiota interactions as moderators of human metabolism
2016 StandoutNature
Farnesoid X Receptor Deficiency Induces Nonalcoholic Steatohepatitis in Low-Density Lipoprotein Receptor-Knockout Mice Fed a High-Fat Diet
2008
Functional interactions between the gut microbiota and host metabolism
2012 StandoutNature
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Molecular Regulation of Hepatic Fibrosis, an Integrated Cellular Response to Tissue Injury
2000 Standout
Risk of Hepatocellular Carcinoma Across a Biological Gradient of Serum Hepatitis B Virus DNA Level
2006 Standout
Clinical relevance of the bile acid receptor TGR5 in metabolism
2016
Regions involved in the opening of CIC-2 chloride channel by voltage and cell volume
1992 Nature
cAMP and Ca2+ act co-operatively on the Cl? conductance of HT29 cells
1992
Apoptosis
2002 Standout
Bile Acids as Regulators of Hepatic Lipid and Glucose Metabolism
2010
Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
2014 Standout
Changes of the plasma metabolome during an oral glucose tolerance test: is there more than glucose to look at?
2008
Dissecting the roles of endothelin,TGF-β and GM-CSF on myofibroblast differentiation by keratinocytes
2004
A constitutively open potassium channel formed by KCNQ1 and KCNE3
2000 StandoutNature
Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease
2010 Standout
Expression and Regulation of the Na+‐K+‐2Cl− Cotransporter NKCC1 in the Normal and CFTR‐Deficient Murine Colon
2003 StandoutNobel
Hepatitis B virus infection
2018
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
Host-directed therapies for bacterial and viral infections
2017
Cross-talk between calcium and cAMP-dependent intracellular signaling pathways. Implications for synergistic secretion in T84 colonic epithelial cells and rat pancreatic acinar cells.
1995 StandoutNobel
Bile acids as regulatory molecules
2009
Long-term hepatitis B infection in a scalable hepatic co-culture system
2017
Lipid signalling couples translational surveillance to systemic detoxification in Caenorhabditis elegans
2015 StandoutNobel
A new class of inhibitors of cAMP-mediated Cl? secretion in rabbit colon, acting by the reduction of cAMP-activated K+ conductance
1995
Cystic Fibrosis Transmembrane Conductance Regulator Mediates the Cyclic Adenosine Monophosphate–Induced Fluid Secretion But Not the Inhibition of Resorption in Mouse Gallbladder Epithelium
1997 StandoutNobel
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
Metabolite profiles and the risk of developing diabetes
2011 Standout
Drug Insight: mechanisms and sites of action of ursodeoxycholic acid in cholestasis
2006
LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength
2016 StandoutNobel
Hypertonic Induction of Aquaporin-5 Expression through an ERK-dependent Pathway
2000 StandoutNobel
Fundamental role of microvilli in the main functions of differentiated cells: Outline of an universal regulating and signaling system at the cell periphery
2010
Stem cell-derived polarized hepatocytes
2020 StandoutNobel
Chloride conductance in HT29 cells: investigations with apical membrane vesicles and RT-PCR
1999
Hepatobiliary transport
2000
Volume-activated Cl− channels
1996
The Receptor TGR5 Mediates the Prokinetic Actions of Intestinal Bile Acids and Is Required for Normal Defecation in Mice
2012
Hepatocellular carcinoma
2022 Standout
Primary sclerosing cholangitis – a comprehensive review
2017
Defining CD95 as a tumor suppressor gene
2000
Update on primary sclerosing cholangitis
2013
A Fibrosis‐Independent Hepatic Transcriptomic Signature Identifies Drivers of Disease Progression in Primary Sclerosing Cholangitis
2020 StandoutNobel
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Hepatocellular Carcinoma
2019 Standout
Role of CFTR in the Colon
2000
Role of Envelopment in the HEV Life Cycle
2016
Optimization-by-design of hepatotropic lipid nanoparticles targeting the sodium-taurocholate cotransporting polypeptide
2019
cGMP and Atrial Natriuretic Factor Regulate Cell Volume of Rabbit Atrial Myocytes
1995
Volume-activated chloride currents are not correlated with P-glycoprotein expression
1995
Causes and Metabolic Consequences of Fatty Liver
2008
Cholinergic ion secretion in human colon requires coactivation by cAMP
1998
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
Iron neurochemistry in Alzheimer's disease and Parkinson's disease: targets for therapeutics
2015
Regulation of an outwardly rectifying Cl‐ conductance in single proximal tubule cells isolated from frog kidney.
1997
A Role of the Bile Salt Receptor FXR in Atherosclerosis
2010
Present and future therapies of hepatitis B: From discovery to cure
2015
The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases
2017 Standout
Bile Salt Transporters: Molecular Characterization, Function, and Regulation
2003
The Interferon-Inducible Protein Tetherin Inhibits Hepatitis B Virus Virion Secretion
2015
Interactions between bile salts, gut microbiota, and hepatic innate immunity
2017
Osmotic swelling-induced activation of the extracellular-signal-regulated protein kinases Erk-1 and Erk-2 in Intestine 407 cells involves the Ras/Raf-signalling pathway
1998
EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma
2018 Standout
Host-Gut Microbiota Metabolic Interactions
2012 StandoutScience
De Novo Carborane-Containing Macrocyclic Peptides Targeting Human Epidermal Growth Factor Receptor
2019 StandoutNobel
Scalable mRNA and siRNA Lipid Nanoparticle Production Using a Parallelized Microfluidic Device
2021 StandoutNobel
Intrahepatic cholestasis of pregnancy
2009
The Engagement of Activating FcγRs Inhibits Primate Lentivirus Replication in Human Macrophages
2006 StandoutNobel
Swelling-activated and isoprenaline-activated chloride currents in guinea pig cardiac myocytes have distinct electrophysiology and pharmacology.
1994
Functional Significance of Cell Volume Regulatory Mechanisms
1998 Standout
Activation of a Cl- current by hypotonic volume increase in human endothelial cells.
1994
Impaired cell volume regulation in intestinal crypt epithelia of cystic fibrosis mice.
1995 StandoutNobel
Interactions Between Gut Microbiota and Host Metabolism Predisposing to Obesity and Diabetes
2010
Works of Ralf Kubitz being referenced
Protein Kinase C-Dependent Distribution of the Multidrug Resistance Protein 2 From the Canalicular to the Basolateral Membrane in Human Hepg2 Cells
2001
Expression and localization of hepatobiliary transport proteins in progressive familial intrahepatic cholestasis†
2005
Biliary Transport Systems: Short‐Term Regulation
2005
Taurine supplementation induces multidrug resistance protein 2 and bile salt export pump expression in rats and prevents endotoxin-induced cholestasis
2003
The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells
2007
Small-conductance Cl? channels in HT29 cells: activation by Ca2+, hypotonic cell swelling and 8-Br-cGMP
1992
Severe liver fibrosis caused by Schistosoma mansoni: management and treatment with a transjugular intrahepatic portosystemic shunt
2015
Heme Oxygenase-1 (HSP-32) and Heme Oxygenase-2 Induction in Neurons and Glial Cells of Cerebral Regions and Its Relation to Iron Accumulation after Focal Cortical Photothrombosis
2001
Expression and function of the bile acid receptor TGR5 in Kupffer cells
2008
Endocrine and paracrine role of bile acids
2008
Short-Term Regulation of Canalicular Transport
2000
Disruption of hepatocellular tight junctions by vascular endothelial growth factor (VEGF): a novel mechanism for tumor invasion
2004
Involvement of CD95 (Apo-1/Fas) ligand expressed by rat Kupffer cells in hepatic immunoregulation
1999
Small and intermediate conductance chloride channels in HT29 cells
1993
Retrieval of the mrp2 Gene Encoded Conjugate Export Pump from the Canalicular Membrane Contributes to Cholestasis Induced by tert-Butyl Hydroperoxide and Chloro-Dinitrobenzene
2000
Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated by the p38 MAP kinase
2004
Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone
1999
Small-conductance chloride channels induced by cAMP, Ca2+, and hypotonicity in HT29 cells: ion selectivity, additivity and stilbene sensitivity
1992
Stable expression and functional characterization of a Na+-taurocholate cotransporting green fluorescent protein in human hepatoblastoma HepG2 cells
2000
The membrane-bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders #
2009
Activation of Rat Hepatic Stellate Cells in Culture Is Associated With Increased Sensitivity to Endothelin 1
1998
Contribution of variant alleles of ABCB11 to susceptibility to intrahepatic cholestasis of pregnancy
2008
Hepatitis B and D Viruses Exploit Sodium Taurocholate Co-transporting Polypeptide for Species-Specific Entry into Hepatocytes
2013
cAMP-dependent activation of small-conductance Cl? channels in HT29 colon carcinoma cells
1992
Release of Osmolytes From Perfused Rat Liver on Perivascular Nerve Stimulation: α–Adrenergic Control of Osmolyte Efflux From Parenchymal and Nonparenchymal Liver Cells
1999
Forskolin and PMA pretreatment of HT29 cells alters their chloride conductance induced by cAMP, Ca2+ and hypotonic cell swelling
1994
Ca2+-dependent Protein Kinase C Isoforms Induce Cholestasis in Rat Liver
2004
Combined Mutations of Canalicular Transporter Proteins Cause Severe Intrahepatic Cholestasis of Pregnancy
2006
Osmosignalling in C6 glioma cells
1997
Osmodependent dynamic localization of the multidrug resistance protein 2 in the rat hepatocyte canalicular membrane
1997
A mutation in the canalicular phospholipid transporter gene, ABCB4, is associated with cholestasis, ductopenia, and cirrhosis in adults†‡
2008
Strategies to Inhibit Entry of HBV and HDV Into Hepatocytes
2014
Dexamethasone- and osmolarity-dependent expression of the multidrug-resistance protein 2 in cultured rat hepatocytes1
1999
Expression and localization of atypical PKC isoforms in liver parenchymal cells
2008
Expression of Glutamine Synthetase in Macrophages
2000
Dexamethasone- and osmolarity-dependent expression of the multidrug-resistance protein 2 in cultured rat hepatocytes1
1999