Citation Impact
Citing Papers
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes
2020 StandoutNobel
An enumerative algorithm for de novo design of proteins with diverse pocket structures
2020 StandoutNobel
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
2016 StandoutScience
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications
2011
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
2020 StandoutNobel
The 2016 revision of the World Health Organization classification of lymphoid neoplasms
2016 Standout
PIEZO ion channel is required for root mechanotransduction in Arabidopsis thaliana
2021 StandoutNobel
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
A pre-screening FISH-based method to detect CRISPR/Cas9 off-targets in mouse embryonic stem cells
2015
CRISPR/Cas9-mediated targeted chromosome elimination
2017
WU-CRISPR: characteristics of functional guide RNAs for the CRISPR/Cas9 system
2015
How specific is CRISPR/Cas9 really?
2015
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
In vivo high-throughput profiling of CRISPR–Cpf1 activity
2016
Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery
2015
Genomic and immunohistochemical profiles of enteropathy-associated T-cell lymphoma in Japan
2015
In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation
2017
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes
2017
A CRISPR–dCas Toolbox for Genetic Engineering and Synthetic Biology
2018
SWI/SNF Regulates the Cellular Response to Hypoxia
2008
Inducible and multiplex gene regulation using CRISPR–Cpf1-based transcription factors
2017
Expanding the CRISPR imaging toolset withStaphylococcus aureusCas9 for simultaneous imaging of multiple genomic loci
2016
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
Integrative Analysis Reveals Relationships of Genetic and Epigenetic Alterations in Osteosarcoma
2012
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
2013 Standout
De novo design of luciferases using deep learning
2023 StandoutNatureNobel
Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system
2017
Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR
2016
Diversity and evolution of class 2 CRISPR–Cas systems
2017
Defining and improving the genome-wide specificities of CRISPR–Cas9 nucleases
2016
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
2017 StandoutNatureNobel
CHOPCHOP v2: a web tool for the next generation of CRISPR genome engineering
2016
Therapeutic genome editing: prospects and challenges
2015
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
2016 Standout
Deep learning improves prediction of CRISPR–Cpf1 guide RNA activity
2018
The coming of age of de novo protein design
2016 StandoutNatureNobel
A Broad-Spectrum Inhibitor of CRISPR-Cas9
2017 StandoutNobel
CRISPR/Cas9-Based Engineering of the Epigenome
2017
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
De novo design of bioactive protein switches
2019 StandoutNatureNobel
Accessing the Phenotype Gap: Enabling Systematic Investigation of Paralog Functional Complexity with CRISPR
2017
An Effective Strategy for Reliably Isolating Heritable and Cas9-Free Arabidopsis Mutants Generated by CRISPR/Cas9-Mediated Genome Editing
2016
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications
2017 StandoutNobel
The Human Condition—A Molecular Approach
2014 StandoutNobel
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
Partial DNA-guided Cas9 enables genome editing with reduced off-target activity
2018
Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9
2016 StandoutNobel
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Massively parallel kinetic profiling of natural and engineered CRISPR nucleases
2020 StandoutNobel
De novo protein design by inversion of the AlphaFold structure prediction network
2023
Simple yet functional phosphate-loop proteins
2018 StandoutNobel
CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing
2019
Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL −/− clear cell renal carcinoma
2017 StandoutNobel
CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine
2017
Systematic discovery of natural CRISPR-Cas12a inhibitors
2018 StandoutScienceNobel
De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity
2024 StandoutNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
CRISPR-CasΦ from huge phages is a hypercompact genome editor
2020 StandoutScienceNobel
Optimization of scarless human stem cell genome editing
2013
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice
2013
Sampling and energy evaluation challenges in ligand binding protein design
2017 StandoutNobel
Computational design of environmental sensors for the potent opioid fentanyl
2017 StandoutNobel
Evaluating and Enhancing Target Specificity of Gene-Editing Nucleases and Deaminases
2019
Parallel Screening for Rapid Identification of Orthogonal Bioluminescent Tools
2017
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Reshaping de Novo Protein Switches into Bioresponsive Materials for Biomarker, Toxin, and Viral Detection
2022 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice
2016
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation
2016
Disabling Cas9 by an anti-CRISPR DNA mimic
2017 StandoutNobel
Works of Raj Chari being referenced
Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells
2014
Comparison of Cas9 activators in multiple species
2016
Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach
2015
Cas9 gRNA engineering for genome editing, activation and repression
2015
An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer
2010
Up regulation in gene expression of chromatin remodelling factors in cervical intraepithelial neoplasia
2008
Whole-Genome Analysis and HLA Genotyping of Enteropathy-Type T-Cell Lymphoma Reveals 2 Distinct Lymphoma Subtypes
2007
Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers
2012
sgRNA Scorer 2.0: A Species-Independent Model To Predict CRISPR/Cas9 Activity
2017
A general strategy to construct small molecule biosensors in eukaryotes
2015 StandoutNobel