Citation Impact
Citing Papers
Rhizobium induces DNA damage in Caenorhabditis elegans intestinal cells
2019 StandoutNobel
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro
2003 StandoutNobel
Combined Inhibition of Wee1 and PARP1/2 for Radiosensitization in Pancreatic Cancer
2014
Preclinical Evaluation of the WEE1 Inhibitor MK-1775 as Single-Agent Anticancer Therapy
2013
A Genetic Variant of Aurora Kinase A Promotes Genomic Instability Leading to Highly Malignant Skin Tumors
2009
T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus
2008
Capturing Chromosome Conformation
2002 StandoutScience
The DNA-damage response in human biology and disease
2009 StandoutNature
DNA damage checkpoints: from initiation to recovery or adaptation
2007
John Snow's legacy: epidemiology without borders
2013 StandoutNobel
Fluorescent Sensors of Protein Kinases
2012
Inflammation and cancer
2002 StandoutNature
A Conserved Checkpoint Pathway Mediates DNA Damage–Induced Apoptosis and Cell Cycle Arrest in C. elegans
2000
mTOR Signaling in Growth Control and Disease
2012 Standout
Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis
2007 StandoutNobel
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
A Conserved Insertion in Protein-primed DNA Polymerases is Involved in Primer Terminus Stabilisation
2003
Meiotic DNA replication checkpoint control in fission yeast
1999 StandoutNobel
Playing the End Game: DNA Double-Strand Break Repair Pathway Choice
2012
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
2005 StandoutNature
Tti1 and Tel2 Are Critical Factors in Mammalian Target of Rapamycin Complex Assembly
2010
Human Homologs of Schizosaccharomyces pombe Rad1, Hus1, and Rad9 Form a DNA Damage-responsive Protein Complex
1999
Telomere states and cell fates
2000 StandoutNatureNobel
PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response
2012
The Human Checkpoint Protein hRad17 Interacts with the PCNA-like Proteins hRad1, hHus1, and hRad9
2000
A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants
2009 StandoutNatureNobel
Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein
2010 StandoutNobel
Asymmetric spiroacetalization catalysed by confined Brønsted acids
2012 StandoutNatureNobel
HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes
2009
A DNA damage checkpoint response in telomere-initiated senescence
2003 StandoutNature
A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene
2009
Regulation of DNA repair throughout the cell cycle
2008
Short Telomeres, even in the Presence of Telomerase, Limit Tissue Renewal Capacity
2005 StandoutNobel
Physical Interactions among Human Checkpoint Control Proteins HUS1p, RAD1p, and RAD9p, and Implications for the Regulation of Cell Cycle Progression
2000
Checkpoint control and cancer
2011
Human and Mouse Homologs of theSchizosaccharomyces pombe rad17Cell Cycle Checkpoint Control Gene
1999
High Expression of Wee1 Is Associated with Poor Disease-Free Survival in Malignant Melanoma: Potential for Targeted Therapy
2012
Therapeutic targeting of Polo-like kinase-1 and Aurora kinases in T-cell acute lymphoblastic leukemia
2014
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Reconstitution and Molecular Analysis of the hRad9-hHus1-hRad1 (9-1-1) DNA Damage Responsive Checkpoint Complex
2001
Mechanisms of Initiation of Linear DNA Replication in Prokaryotes
1999
Mitotic DNA Damage Response: At the Crossroads of Structural and Numerical Cancer Chromosome Instabilities
2017
Initial testing of the aurora kinase a inhibitor MLN8237 by the Pediatric Preclinical Testing Program (PPTP)
2010
Retention of the Human Rad9 Checkpoint Complex in Extraction-resistant Nuclear Complexes after DNA Damage
2000
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
Comparing effects of mTR and mTERT deletion on gene expression and DNA damage response: a critical examination of telomere length maintenance-independent roles of telomerase
2009 StandoutNobel
Cyclin B2 and p53 control proper timing of centrosome separation
2014
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
2005 StandoutNature
The Hallmarks of Aging
2013 Standout
Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases
2012 StandoutNobel
The role of the DNA double-strand break response network in meiosis
2004
Emerging links between the biological clock and the DNA damage response
2007
A human DNA editing enzyme homologous to the Escherichia coli DnaQ/MutD protein
1999
1,n‐Hydrogen‐Atom Transfer (HAT) Reactions in Which n≠5: An Updated Inventory
2014
Human DNA Damage Checkpoint Protein hRAD9 Is a 3′ to 5′ Exonuclease
2000 StandoutNobel
TopBP1 Activates the ATR-ATRIP Complex
2006
MRT-2 checkpoint protein is required for germline immortality and telomere replication in C. elegans
2000 Nature
Intramolecular 1,8‐Hydrogen‐Atom Transfer Reactions in (1→4)‐O‐Disaccharide Systems: Conformational and Stereochemical Requirements
2008
DNA damage response at functional and dysfunctional telomeres
2008
HRad17 Colocalizes with NHP2L1 in the Nucleolus and Redistributes after UV Irradiation
1999
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
2015 StandoutNobel
Intramolecular Hydrogen Abstraction Promoted by Amidyl Radicals. Evidence for Electronic Factors in the Nucleophilic Cyclization of Ambident Amides to Oxocarbenium Ions
2005
One-step axial acetoxylation at C-23. A new method for the functionalization of the side chain of steroid sapogenins
2006
Facile radical decarboxylative alkylation of heteroaromatic bases using carboxylic acids and trivalent iodine compounds
1991
Meiotic Chromosomes: Integrating Structure and Function
1999
Radical decarboxylative alkylation onto heteroaromatic bases with trivalent iodine compounds
1993
Inactivation of mouse Hus1 results in genomic instability and impaired responses to genotoxic stress
2000
Sequential alkoxy radical fragmentation. A one-step method for breaking two 1,3-positioned CC bonds
1993
Chemistry of Polyvalent Iodine
2008 Standout
Telomerase core components protect Candida telomeres from aberrant overhang accumulation
2007 StandoutNobel
A specific subdomain in φ29 DNA polymerase confers both processivity and strand-displacement capacity
2005 StandoutNobel
A novel mutant allele of the chromatin-bound fission yeast checkpoint protein Rad17 separates the DNA structure checkpoints
2000 StandoutNobel
Purification and characterization of human DNA damage checkpoint Rad complexes
2001 StandoutNobel
Study on Radical Amidation onto Aromatic Rings with (Diacyloxyiodo)arenes
1998
Synthesis of oxa-aza spirobicycles by intramolecular hydrogen atom transfer promoted by N-radicals in carbohydrate systems
2009
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA
2007 StandoutNobel
Fragmentation of Carbohydrate Anomeric Alkoxyl Radicals. A New Synthesis of Chiral β-Iodo Azides, Vinyl Azides, and 2H-Azirines
2003
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling
2010 StandoutNobel
Solvent-Controlled Oxidative Cyclization for Divergent Synthesis of Highly Functionalized Oxetanes and Cyclopropanes
2009
Quality Control by DNA Repair
1999 StandoutScienceNobel
The Human G2 Checkpoint Control Protein hRAD9 Is a Nuclear Phosphoprotein That Forms Complexes with hRAD1 and hHUS1
1999
Polycycle construction via cascade radical fragmentation transannulation-cyclisation processes
1993
Nonanomeric Spiroketals in Natural Products: Structures, Sources, and Synthetic Strategies
2005
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
2002 StandoutNobel
Intramolecular 1,5-hydrogen atom transfer reaction promoted by phosphoramidyl and carbamoyl radicals: synthesis of 2-amino-C-glycosides
2007
New synthetic method to 1,2-benzisothiazoline-3-one- 1,1-dioxides and 1,2-benzisothiazoline-3-one-1-oxides from N-alkyl(o-methyl) arenesulfonamides
1999
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
2019 StandoutNobel
Asymmetric heck reaction. A catalytic asymmetric synthesis of the key intermediate for vernolepin
1993
Favorskii rearrangement of 23-oxo-3-epi-smilagenin acetate induced by iodosobenzene
2005
Copper-Catalyzed Synthesis of Mixed Alkyl Aryl Phosphonates
2014 StandoutNobel
Alkylation of Aromatic Heterocycles with Oxalic Acid Monoalkyl Esters in the Presence of Trivalent Iodine Compounds
1991
The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types
2002 StandoutNobel
A Highly Enantioselective Intramolecular Heck Reaction with a Monodentate Ligand
2001 StandoutNobel
Organic Polyvalent Iodine Compounds
1996 Standout
Sequential alkoxy radical fragmentation-cyclopropylcarbinyl rearrangement. Synthesis of highly functionalized eleven-membered rings
1994
Benzylic-acetoxylation of alkylbenzenes with PhI(OAc)2 in the presence of catalytic amounts of TsNH2 and I2
2011
Fragmentation of alkoxy radicals: Tandem β-fragmentation-cycloperoxyiodination reaction
1992
Host Cell DNA Repair Pathways in Adeno-Associated Viral Genome Processing
2006
Reductive addition to electron-deficient olefins with trivalent iodine compounds
1993
Exo1 and Rad24 Differentially Regulate Generation of ssDNA at Telomeres of Saccharomyces cerevisiae cdc13-1 Mutants
2004
One-carbon extrusion from carbohydrates via C1-alkoxy radical fragmentation. An easy access to erythrose and threose
1992
Recent Developments in the Chemistry of Polyvalent Iodine Compounds
2002
Cancer Genome Landscapes
2013 StandoutScience
ATM-dependent Phosphorylation of Human Rad9 Is Required for Ionizing Radiation-induced Checkpoint Activation
2001
WormBook
2008
Hypervalent iodine reagents: Synthesis of a steroidal orthoacetate by a radical reaction
1994
1,8‐Hydrogen Atom Transfer Promoted by N‐Radicals in (1→4)‐O‐Disaccharide Models
2011
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
P53 Binding Protein 1 (53bp1) Is an Early Participant in the Cellular Response to DNA Double-Strand Breaks
2000
Intramolecular Hydrogen Abstraction Reaction Promoted by N-Radicals in Carbohydrates. Synthesis of Chiral 7-Oxa-2-azabicyclo[2.2.1]heptane and 8-Oxa-6-azabicyclo[3.2.1]octane Ring Systems
2003
Hydrogen atom transfer experiments provide chemical evidence for the conformational differences between C- and O-glycosides
2007
Haploinsufficiency of t e lomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita
2005 StandoutNobel
Genetic Control of Recombination Partner Preference in Yeast Meiosis: Isolation and Characterization of Mutants Elevated for Meiotic Unequal Sister-Chromatid Recombination
1999
Use and Abuse of RNAi to Study Mammalian Gene Function
2012 StandoutScienceNobel
Reagents with Hypervalent Iodine: Formation of Convenient Chiral Synthetic Intermediates by Fragmentation of Carbohydrate Anomeric Alkoxy Radicals
1992
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
Interfaces Between the Detection, Signaling, and Repair of DNA Damage
2002 Science
How Shelterin Protects Mammalian Telomeres
2008 Standout
Catalytic Asymmetric Transacetalization
2010 StandoutNobel
The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1
2004 StandoutNobel
Intramolecular Hydrogen Abstraction Reaction Promoted by Alkoxy Radicals in Carbohydrates. Synthesis of Chiral 2,7-Dioxabicyclo[2.2.1]heptane and 6,8-Dioxabicyclo[3.2.1]octane Ring Systems
2002
Preferential binding of ATR protein to UV-damaged DNA
2002 StandoutNobel
Cyclic Carbopalladation. A Versatile Synthetic Methodology for the Construction of Cyclic Organic Compounds
1996 StandoutNobel
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Discovery of Hypoiodite-Mediated Aminyl Radical Cyclization Lacking a Nitrogen Radical-Stabilizing Group: Application to Synthesis of an Oxazaspiroketal-Containing Cephalostatin Analog
2011
Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma
2014
Works of Raimundo Freire being referenced
The association of ATR protein with mouse meiotic chromosome cores
1999
Mammalian BTBD12 (SLX4) Protects against Genomic Instability during Mammalian Spermatogenesis
2011
HCLK2 Is Required for Activity of the DNA Damage Response Kinase ATR
2008
Activation of Replication Origins in ϕ29-related Phages Requires the Recognition of Initiation Proteins to Specific Nucleoprotein Complexes
1996
Polo-like Kinase-1 Controls Proteasome-Dependent Degradation of Claspin during Checkpoint Recovery
2006
Claspin: Timing the Cell Cycle Arrest When the Genome is Damaged
2006
Telomere and Telomerase Modulation by the Mammalian Rad9/Rad1/Hus1 DNA-Damage-Checkpoint Complex
2006
Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery
2008 Nature
Phage Ø29 protein p6: A viral histone-like protein
1994
Human and mouse homologs ofSchizosaccharomyces pombe rad1+andSaccharomyces cerevisiae RAD17:linkage to checkpoint control and mammalian meiosis
1998
Hypervalent organoiodine compounds: radical fragmentation of oxabicyclic hemiacetals. Convenient synthesis of medium-sized and spiro lactones
1991
Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease
2011
β-Fragmentation of alkoxy radicals. An approach to the synthesis of ring a of vernolepin
1987
Tandem β-fragmentation-intramolecular functionalization of alkoxyradicals. An approach to the synthesis of a and a'rings of limonin
1987
Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1
2004
Expression and nuclear localization of BLM, a chromosome stability protein mutated in Bloom’s syndrome, suggest a role in recombination during meiotic prophase
2000
Intramolecular 1,5- versus 1,6-Hydrogen Abstraction Reaction Promoted by Alkoxy Radicals in Carbohydrate Models
2002
Intramolecular 1,5- versus 1,6-Hydrogen Abstraction Reaction Promoted by Alkoxy Radicals in Carbohydrate Models
2002
A Convenient Synthesis of C-22 and C-25 Stereoisomers of Cephalostatin North 1 Side Chain from Spirostan Sapogenins
2002
Synthesis of oxa-aza spirobicycles by intramolecular hydrogen abstraction promoted by N -radicals in carbohydrate systems
2002
Intramolecular 1,5- versus 1,6-hydrogen abstraction reaction promoted by alkoxyl radicals in pyranose and furanose models
2007
TopBP1 and ATR Colocalization at Meiotic Chromosomes: Role of TopBP1/Cut5 in the Meiotic Recombination Checkpoint
2004
Fragmentation of Carbohydrate Anomeric Alkoxy Radicals. Synthesis of Polyhydroxy Piperidines and Pyrrolidines Related to Carbohydrates
2001
New sources of steroid sapogenins—VIII
1970
Fragmentation of carbohydrate anomeric alkoxy radicals. Synthesis of azasugars
1997
Seven-membered cyclic transition state in the alkoxy-radical induced intramolecular hydrogen abstraction of 26-hydroxy-furostans
1983
Stereospecific Synthesis of 1,6-Dioxadecalins and 2,2‘-Linked Ditetrahydrofurans by Rearrangement of Steroidal Spiroacetals
1998