Citation Impact
Citing Papers
Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
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Comparison of Two Fluid-Management Strategies in Acute Lung Injury
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Early interventions in severe sepsis and septic shock: a review of the evidence one decade later.
2012
Immunomodulation in the critically ill
2009
An evaluation of the end points of resuscitation11The opinions and assertions contained herein are the private views of the author and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense. This article is based on a review first reported in the Journal of the US Army Medical Department 1997; PB 8-97-11/12:30-34.
1998
Transient expression of IL-1β induces acute lung injury and chronic repair leading to pulmonary fibrosis
2001 Standout
Acute kidney injury
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Pathogenetic Mechanisms of Septic Shock
1993 Standout
Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock
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MYC on the Path to Cancer
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Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis
2004 Standout
Pro-resolving lipid mediators are leads for resolution physiology
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The NLRP3 inflammasome: molecular activation and regulation to therapeutics
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Understanding the Inflammatory Cytokine Response in Pneumonia and Sepsis
2007
SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials
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Animal models of sepsis and sepsis-induced kidney injury
2009
Antithrombin III in patients with severe sepsis
1998
Effects of perfusion pressure on tissue perfusion in septic shock
2000
Pathophysiology of Sepsis
2007
Malignant astrocytic glioma: genetics, biology, and paths to treatment
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Early Goal-Directed Therapy in Severe Sepsis and Septic Shock Revisited
2006
A Randomized, Controlled Trial of the Use of Pulmonary-Artery Catheters in High-Risk Surgical Patients
2003 Standout
Fatal Postoperative Pulmonary Edema
1999
Elevation of Cardiac Output and Oxygen Delivery Improves Outcome in Septic Shock
1992
The Next Generation of Sepsis Clinical Trial Designs
2014
Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy
2013 Standout
Severe Sepsis and Septic Shock
2013 Standout
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
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Unresponsiveness of MyD88-Deficient Mice to Endotoxin
1999 Standout
Sepsis and septic shock
2018 Standout
A new synthetic TLR4 agonist, GLA, allows dendritic cells targeted with antigen to elicit Th1 T‐cell immunity in vivo
2011 StandoutNobel
Post-randomisation exclusions: the intention to treat principle and excluding patients from analysis
2002
Management of Chronic Kidney Disease Patients in the Intensive Care Unit: Mixing Acute and Chronic Illness
2017 Standout
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
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Effect of salt and water balance on recovery of gastrointestinal function after elective colonic resection: a randomised controlled trial
2002 Standout
Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages
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Cardiac Fibroblasts Contribute to Myocardial Dysfunction in Mice with Sepsis: The Role of NLRP3 Inflammasome Activation
2014
Clinical Practice Guidelines for Hospital‐Acquired Pneumonia and Ventilator‐Associated Pneumonia in Adults
2007
The Pathophysiology and Treatment of Sepsis
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Mechanisms and Functions of Inflammasomes
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COVID-19: consider cytokine storm syndromes and immunosuppression
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Protective and pathogenic functions of macrophage subsets
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Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
2012
Disseminated Intravascular Coagulation
1999 Standout
The Myc-dependent angiogenic switch in tumors is mediated by interleukin 1β
2006
The immunopathology of sepsis and potential therapeutic targets
2017 Standout
The coagulopathy of acute sepsis
2015
Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome
2015
Monocyte deactivation-rationale for a new therapeutic strategy in sepsis
1996
Cancer-related inflammation
2008 StandoutNature
The inflammatory reflex
2002 StandoutNature
Monophosphoryl Lipid A (MPL) Formulations for the Next Generation of Vaccines
1999
Lactate Measurements in Sepsis-Induced Tissue Hypoperfusion
2014
Autoinflammation: The prominent role of IL-1 in monogenic autoinflammatory diseases and implications for common illnesses
2009
Practice parameters for hemodynamic support of sepsis in adult patients: 2004 update
2004
Assessment of Clinical Criteria for Sepsis
2016 Standout
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
2016 Standout
Incidence, risk factors, and outcome of severe sepsis and septic shock in adults. A multicenter prospective study in intensive care units. French ICU Group for Severe Sepsis.
1995
Molecular mechanism in tolerance to lipopolysaccharide.
1995
The NLRP3 inflammasome in health and disease: the good, the bad and the ugly
2011
Human tumor necrosis factor receptor (p55) and interleukin 10 gene transfer in the mouse reduces mortality to lethal endotoxemia and also attenuates local inflammatory responses.
1995
Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women
2014 Standout
The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
2019 Standout
Overview of the IL ‐1 family in innate inflammation and acquired immunity
2017
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock
2004 Standout
Functions of interleukin 1 receptor antagonist in gene knockout and overproducing mice.
1996
Klebsiella pneumoniae: Going on the Offense with a Strong Defense
2016 Standout
Immunological and Inflammatory Functions of the Interleukin-1 Family
2009 Standout
Interleukin 10 reduces mortality from severe peritonitis in mice
1995
Roles of Infectious Agents in Atherosclerosis and Restenosis
1997 Standout
Cytokine induction by lipopolysaccharide (LPS) corresponds to lethal toxicity and is inhibited by nontoxic Rhodobacter capsulatus LPS
1990
Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation
2002
Cytokine Storm
2020 Standout
Targeting Interleukin-1 in Heart Disease
2013
Hypoxia-Inducible Factor 1 and Dysregulated c-Myc Cooperatively Induce Vascular Endothelial Growth Factor and Metabolic Switches Hexokinase 2 and Pyruvate Dehydrogenase Kinase 1
2007 StandoutNobel
Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease
2020 Standout
Interleukin-10 and the Interleukin-10 Receptor
2001 Standout
A Randomized Trial of Protocol-Based Care for Early Septic Shock
2014 Standout
Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure
2011 Standout
Interleukin-1 blockade for the treatment of pericarditis
2017
The Pathogenesis of Sepsis
2011
Targeted adenovirus-induced expression of IL-10 decreases thymic apoptosis and improves survival in murine sepsis
2001
Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response
2004 Standout
Developing a New Definition and Assessing New Clinical Criteria for Septic Shock
2016 Standout
EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis
2018 Standout
Sepsis: Multiple Abnormalities, Heterogeneous Responses, and Evolving Understanding
2013
Innate Immune Responses to Microbial Poisons: Discovery and Function of the Toll-Like Receptors
2003 StandoutNobel
Integrating mechanisms of pulmonary fibrosis
2011 Standout
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Induction of endotoxin tolerance with monophosphoryl lipid A in peritonitis: importance of localized therapy.
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Increases in oxygen extraction during rapidly fatal septic shock in rats.
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Monophosphoryl lipid A blocks the hemodynamic effects of lethal endotoxemia.
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Monophosphoryl lipid A attenuates the effects of endotoxic shock in pigs.
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Oxygen delivery and utilization during rapidly fatal septic shock in rats.
1986