Citation Impact
Citing Papers
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
2012 StandoutScience
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
2012 StandoutScience
High burden and pervasive positive selection of somatic mutations in normal human skin
2015 StandoutScience
Nucleic Acid Immunity
2016
Error‐free and mutagenic processing of topoisomerase 1‐provoked damage at genomic ribonucleotides
2015
UV Light Potentiates STING (Stimulator of Interferon Genes)-dependent Innate Immune Signaling through Deregulation of ULK1 (Unc51-like Kinase 1)
2015 StandoutNobel
Redundancy in ribonucleotide excision repair: Competition, compensation, and cooperation
2015
Mitochondrial double-stranded RNA triggers antiviral signalling in humans
2018 Nature
The Circadian Clock Controls Sunburn Apoptosis and Erythema in Mouse Skin
2014 StandoutNobel
Interferon-λ: Immune Functions at Barrier Surfaces and Beyond
2015
Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2′,3′ cGAMP Signaling
2015 StandoutNobel
Type I interferonopathies: Mendelian type I interferon up-regulation
2014
Autophagy in infection, inflammation and immunity
2013 Standout
Ultrasensitive deletion detection links mitochondrial DNA replication, disease, and aging
2020
R loops: new modulators of genome dynamics and function
2015
cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
2013 StandoutNature
Discriminating self from non-self in nucleic acid sensing
2016
Regulation and function of the cGAS–STING pathway of cytosolic DNA sensing
2016 Standout
A Facile Method for the Removal of dsRNA Contaminant from In Vitro-Transcribed mRNA
2019 StandoutNobel
RIG-I-like receptors: their regulation and roles in RNA sensing
2020
Molecular mechanisms and cellular functions of cGAS–STING signalling
2020
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Ribonucleotides in DNA: Origins, repair and consequences
2014
Approaches to treat immune hot, altered and cold tumours with combination immunotherapies
2019 Standout
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
Imipramine Treatment and Resiliency Exhibit Similar Chromatin Regulation in the Mouse Nucleus Accumbens in Depression Models
2009
Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity
2015 Standout
The multidimensional mechanisms of long noncoding RNA function
2017 Standout
Hallmarks of aging: An expanding universe
2023 Standout
Target preference of Type III-A CRISPR-Cas complexes at the transcription bubble
2019 StandoutNobel
Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity
2014 StandoutNobel
Ageing as a risk factor for neurodegenerative disease
2019 Standout
Structure and function of long noncoding RNAs in epigenetic regulation
2013 Standout
STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
2014 Standout
The molecular machinery of regulated cell death
2019 Standout
MITOS: Improved de novo metazoan mitochondrial genome annotation
2012 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus
2014 StandoutNobel
Mitochondrial dysfunction induces RNA interference in C. elegans through a pathway homologous to the mammalian RIG-I antiviral response
2020 StandoutNobel
Cellular senescence in ageing: from mechanisms to therapeutic opportunities
2020 Standout
Inflammation and tumor progression: signaling pathways and targeted intervention
2021 Standout
Long noncoding RNAs in viral infections
2015
Reduction of hRNase H2 activity in Aicardi–Goutières syndrome cells leads to replication stress and genome instability
2014
The cGAS-cGAMP-STING Pathway of Cytosolic DNA Sensing and Signaling
2014
Pro-inflammation Associated with a Gain-of-Function Mutation (R284S) in the Innate Immune Sensor STING
2018
RNA∶DNA Hybrids Initiate Quasi-Palindrome-Associated Mutations in Highly Transcribed Yeast DNA
2013
Interferons and viruses: an evolutionary arms race of molecular interactions
2015 StandoutNobel
The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity
2017 StandoutNobel
Topoisomerase 1-Mediated Removal of Ribonucleotides from Nascent Leading-Strand DNA
2013
Communication by Extracellular Vesicles: Where We Are and Where We Need to Go
2016 Standout
Major Depressive Disorder
2008 Standout
Causes and consequences of replication stress
2013
The biogenesis, biology and characterization of circular RNAs
2019 Standout
Mitochondria as multifaceted regulators of cell death
2019 Standout
Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation
2020 StandoutNobel
Mitochondrial TCA cycle metabolites control physiology and disease
2020 Standout
ROS and the DNA damage response in cancer
2018 Standout
Analysis of Ribonucleotide Removal from DNA by Human Nucleotide Excision Repair
2015 StandoutNobel
RNase H2-Initiated Ribonucleotide Excision Repair
2012
Transcriptional responses to loss of RNase H2 in Saccharomyces cerevisiae
2012
Genetic aspects of mitochondrial genome evolution
2012
Toll-Like Receptor Signaling Pathways
2014 Standout
R Loops: From Transcription Byproducts to Threats to Genome Stability
2012
Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development
2015
Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy
2017
Removal of Misincorporated Ribonucleotides from Prokaryotic Genomes: An Unexpected Role for Nucleotide Excision Repair
2013
Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity
2013 StandoutNobel
Immunomodulation in Cystic Fibrosis: Why and How?
2020
cGAS in action: Expanding roles in immunity and inflammation
2019 Science
Ribonuclease H2 in health and disease
2014
Lipid Nanoparticles Delivering Constitutively Active STING mRNA to Stimulate Antitumor Immunity
2022 StandoutNobel
Mitochondrial DNA in innate immune responses and inflammatory pathology
2017
Eukaryotic DNA Replication Fork
2017
Biochemical properties of mammalian TREX1 and its association with DNA replication and inherited inflammatory disease
2009 StandoutNobel
DAMP-sensing receptors in sterile inflammation and inflammatory diseases
2019 Standout
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger
2013 Standout
Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome
2014
Viruses transfer the antiviral second messenger cGAMP between cells
2015 Science
RNase H2 catalytic core Aicardi-Goutières syndrome–related mutant invokes cGAS–STING innate immune-sensing pathway in mice
2016
The cGAS–cGAMP–STING pathway connects DNA damage to inflammation, senescence, and cancer
2018
Comet-FISH with strand-specific probes reveals transcription-coupled repair of 8-oxoGuanine in human cells
2013
Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity
2012
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Works of Rachel E. Rigby being referenced
RNA:DNA hybrids are a novel molecular pattern sensed by TLR9
2014
Ribonuclease H2 mutations induce a cGAS / STING ‐dependent innate immune response
2016
SAMHD1‐dependent retroviral control and escape in mice
2013
Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development
2012
Mammalian Mitochondrial DNA Replication Intermediates Are Essentially Duplex but Contain Extensive Tracts of RNA/DNA Hybrid
2010
Nucleic acid‐mediated inflammatory diseases
2008
RNA degradation in antiviral immunity and autoimmunity
2015
Infection with a Brazilian isolate of Zika virus generates RIG‐I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling
2018