Standout Papers
- The Acidic Transcription Activator Gcn4 Binds the Mediator Subunit Gal11/Med15 Using a Simple Protein Interface Forming a Fuzzy Complex (2011)
- Interaction of calmodulin and a calmodulin-binding peptide from myosin light chain kinase: major spectral changes in both occur as the result of complex formation (1985)
- Intrinsic disorder drives N-terminal ubiquitination by Ube2w (2014)
- Structural and kinetic characterization of the simplified SH3 domain FP1 (2003)
- Prediction and structural characterization of an independently folding substructure in the src SH3 domain (1998)
Citation Impact
Citing Papers
Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells
2002 StandoutScienceNobel
Shaping up the protein folding funnel by local interaction: Lesson from a structure prediction study
2006
GEMME: A Simple and Fast Global Epistatic Model Predicting Mutational Effects
2019
Principles for designing proteins with cavities formed by curved β sheets
2017 StandoutScienceNobel
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants
2019 StandoutScienceNobel
Zinc Finger-DNA Recognition: Crystal Structure of a Zif268-DNA Complex at 2.1 Å
1991 StandoutScience
The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity
2002
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
The Metal Binding Site of the Hepatitis C Virus NS3 Protease
1998
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
A statistical framework for analyzing deep mutational scanning data
2017
Matching theory and experiment in protein folding
1999 StandoutNobel
Demonstration by NMR of folding domains in lysozyme
1991 StandoutNatureNobel
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Biomolecular magic-angle spinning solid-state NMR: recent methods and applications
2013
Experiment and theory highlight role of native state topology in SH3 folding.
1999 StandoutNobel
Deep Mutational Scanning: A Highly Parallel Method to Measure the Effects of Mutation on Protein Function
2015
Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA
1991 StandoutNature
Atomic model of the type III secretion system needle
2012 StandoutNatureNobel
Accurate classification of BRCA1 variants with saturation genome editing
2018 Nature
In vitro selection of zinc fingers with altered DNA-binding specificity
1994
Sequential proton NMR assignments and secondary structure of hen egg white lysozyme in solution
1988
The structure of ribosomal protein S5 reveals sites of interaction with 16S rRNA
1992 StandoutNatureNobel
Structural basis for initiation of transcription from an RNA polymerase–promoter complex
1999 StandoutNatureNobel
Hierarchy of structure loss in MD simulations of src SH3 domain unfolding
1999 StandoutNobel
BPPred: A Web‐based computational tool for predicting biophysical parameters of proteins
2006
Formation of a stable triplex from a single DNA strand
1990 Nature
Crystal structure of the FimD usher bound to its cognate FimC–FimH substrate
2011 Nature
Stereochemical basis of DNA recognition by Zn fingers
1994
CD137 (4-1BB) Signalosome: Complexity Is a Matter of TRAFs
2018
Principles for designing ideal protein structures
2012 StandoutNatureNobel
Engineering allostery
2014
Refined crystal structure of troponin C from turkey skeletal muscle at 2·0 Å resolution
1988
Molecular Tuning of Ion Binding to Calcium Signaling Proteins
1994
Zinc finger motif for single‐stranded nucleic acids? investigations by nuclear magnetic resonance
1991
A mediator required for activation of RNA polymerase II transcription in vitro
1991 StandoutNatureNobel
Mitochondria: In Sickness and in Health
2012 Standout
Engineered Metal-Binding Proteins: Purification to Protein Folding
1991 StandoutScienceNobel
Mechanisms of mitochondrial diseases
2011
Evolution of a designed protein assembly encapsulating its own RNA genome
2017 StandoutNatureNobel
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
Structural studies of protein–nucleic acid interaction: the sources of sequence-specific binding
1990 StandoutNobel
The crystal structure of a two zinc-finger peptide reveals an extension to the rules for zinc-finger/DNA recognition
1993 Nature
DNA recognition by GAL4: structure of a protein-DNA complex
1992 Nature
Enhancement of BRCA1 E3 Ubiquitin Ligase Activity through Direct Interaction with the BARD1 Protein
2003
Structural and energetic basis of folded-protein transport by the FimD usher
2013 StandoutNatureNobel
Massively parallel determination and modeling of endonuclease substrate specificity
2014 StandoutNobel
Structure and function of voltage‐gated sodium channels at atomic resolution
2013
Themes and variations on ubiquitylation
2001
Triple-strand formation in the homopurine:homopyrimidine DNA oligonucleotides d(G-A)4 and d(T-C)4
1989 Nature
The RING Heterodimer BRCA1-BARD1 Is a Ubiquitin Ligase Inactivated by a Breast Cancer-derived Mutation
2001
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
De novo design of bioactive protein switches
2019 StandoutNatureNobel
Mutation effects predicted from sequence co-variation
2017
Prediction of local structure in proteins using a library of sequence-structure motifs
1998 StandoutNobel
Nucleocapsid zinc fingers detected in retroviruses: EXAFS studies of intact viruses and the solution‐state structure of the nucleocapsid protein from HIV‐1
1992
Mdm2 Is a RING Finger-dependent Ubiquitin Protein Ligase for Itself and p53
2000
Structure of the carboxy-terminal LIM domain from the cysteine rich protein CRP
1994
Autoubiquitination of the BRCA1·BARD1 RING Ubiquitin Ligase
2002
Helix capping
1998
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
Cu(II)‐Binding properties of a cytochrome c with a synthetic metal‐binding site: His‐X3‐His in an α‐helix
1991 StandoutNobel
A surprising simplicity to protein folding
2000 StandoutNatureNobel
MdmX Is a RING Finger Ubiquitin Ligase Capable of Synergistically Enhancing Mdm2 Ubiquitination
2002
High-resolution structure of an HIV zinc fingerlike domain via a new NMR-based distance geometry approach
1990
Molecular and Structural Basis of Target Recognition by Calmodulin
1995
Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin
1997 StandoutNatureNobel
Deep mutational scanning: a new style of protein science
2014
Christian Raetz: Scientist and Friend Extraordinaire
2013 StandoutNobel
Three-Dimensional Solution Structure of a Single Zinc Finger DNA-Binding Domain
1989 Science
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
13C Spin Dilution for Simplified and Complete Solid-State NMR Resonance Assignment of Insoluble Biological Assemblies
2011
Determination of the base recognition positions of zinc fingers from sequence analysis.
1992
Ca2+ binding and conformational change in two series of point mutations to the individual Ca(2+)-binding sites of calmodulin.
1992
Regulation of Receptor Fate by Ubiquitination of Activated β 2 -Adrenergic Receptor and β-Arrestin
2001 StandoutScienceNobel
Recent Advances in Magic‐Angle Spinning Solid‐State NMR of Proteins
2014
Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-II
1990 StandoutNatureNobel
Exploration of Structured Symmetric Cyclic Peptides as Ligands for Metal-Organic Frameworks
2022 StandoutNobel
Sp1 and the subfamily of zinc finger proteins with guanine-rich binding sites.
1992
N-degron and C-degron pathways of protein degradation
2019
Mutations in the zinc fingers of ADR1 that change the specificity of DNA binding and transactivation.
1992
The Galvanization of Biology: A Growing Appreciation for the Roles of Zinc
1996 StandoutScience
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Zinc fingers and other metal-binding domains. Elements for interactions between macromolecules.
1990
Recognition Dynamics Up to Microseconds Revealed from an RDC-Derived Ubiquitin Ensemble in Solution
2008 Science
Transition Metals in Control of Gene Expression
1993 Science
Specificity for Aminoacylation of an RNA Helix: an Unpaired, Exocyclic Amino Group in the Minor Groove
1991 StandoutScienceNobel
A retroviral Cys-Xaa2-Cys-Xaa4-His-Xaa4-Cys peptide binds metal ions: spectroscopic studies and a proposed three-dimensional structure.
1989
Building zinc fingers by selection: toward a therapeutic application.
1995
High thermodynamic stability of parametrically designed helical bundles
2014 StandoutScienceNobel
RNA-binding domain of the A protein component of the U1 small nuclear ribonucleoprotein analyzed by NMR spectroscopy is structurally similar to ribosomal proteins.
1991
Molecular Matchmakers
1993 StandoutScienceNobel
Solution structure of a calmodulin-target peptide complex by multidimensional NMR
1992 Science
DeMaSk: a deep mutational scanning substitution matrix and its use for variant impact prediction
2020
Building and remodelling Cullin–RING E3 ubiquitin ligases
2013
NMR Structure of a Specific DNA Complex of Zn-Containing DNA Binding Domain of GATA-1
1993 Science
The NMR–Rosetta capsid model of M13 bacteriophage reveals a quadrupled hydrophobic packing epitope
2015 StandoutNobel
Use of a zinc-finger consensus sequence framework and specificity rules to design specific DNA binding proteins.
1993
Activation of four enzymes by two series of calmodulin mutants with point mutations in individual Ca2+ binding sites.
1993
Solution Structure of the Glucocorticoid Receptor DNA-Binding Domain
1990 Science
Crystal Structure of a CAP-DNA Complex: the DNA Is Bent by 90°
1991 StandoutScienceNobel
Similarities and Differences within Members of the Ff Family of Filamentous Bacteriophage Viruses
2011
Structure of DNA Polymerase I Klenow Fragment Bound to Duplex DNA
1993 StandoutScienceNobel
Mutations in the Zinc Fingers of ADR1 That Change the Specificity of DNA Binding and Transactivation
1992
Yeast TATA-box transcription factor gene.
1989
Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins
1989 StandoutScience
Three-dimensional structure of calmodulin
1985 StandoutNature
Principles of Allosteric Interactions in Cell Signaling
2014
Lipid A Modification Systems in Gram-Negative Bacteria
2007
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
Salmonella Synthesizing 1-Monophosphorylated Lipopolysaccharide Exhibits Low Endotoxic Activity while Retaining Its Immunogenicity
2011
Solution structure of the DMA-binding domain of the oestrogen receptor
1990 Nature
Magic-Angle Spinning NMR of a Class I Filamentous Bacteriophage Virus
2011
MODERN APPLICATIONS OF ANALYTICAL ULTRACENTRIFUGATION
1999
Zinc Finger Phage: Affinity Selection of Fingers with New DNA-Binding Specificities
1994 Science
Toward rules relating zinc finger protein sequences and DNA binding site preferences.
1992
Two Identical Noninteracting Sites in an Ion Channel Revealed by Proton Transfer
1994 StandoutScienceNobel
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Crystal Structure of a Five-Finger GLI-DNA Complex: New Perspectives on Zinc Fingers
1993 Science
PhoPQ-Mediated Regulation Produces a More Robust Permeability Barrier in the Outer Membrane ofSalmonella entericaSerovar Typhimurium
2007
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
Works of Rachel E. Klevit being referenced
Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis
2013
Following Ariadne's thread: a new perspective on RBR ubiquitin ligases
2012
Recognition of Antimicrobial Peptides by a Bacterial Sensor Kinase
2005
The Cancer-predisposing Mutation C61G Disrupts Homodimer Formation in the NH2-terminal BRCA1 RING Finger Domain
1998
NMR chemical shift perturbation mapping of dna binding by a zinc‐finger domain from the yeast transcription factor ADR1
1997
Mapping the Functional Domains of BRCA1
1999
Ubiquitin Transfer from the E2 Perspective: Why is UbcH5 So Promiscuous?
2006
Regulating the Regulators: Recent Revelations in the Control of E3 Ubiquitin Ligases
2015
RING-type E3 ligases: Master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination
2013
Increased helix and protein stability through the introduction of a new tertiary hydrogen bond 1 1P.E. Wright
1999
αB-Crystallin: A Hybrid Solid-State/Solution-State NMR Investigation Reveals Structural Aspects of the Heterogeneous Oligomer
2008
BRCA1 RING Domain Cancer-predisposing Mutations
2001
Solid-state NMR and SAXS studies provide a structural basis for the activation of αB-crystallin oligomers
2010
Structural Basis for Mechanical Force Regulation of the Adhesin FimH via Finger Trap-like β Sheet Twisting
2010
Metal Bridges between the PhoQ Sensor Domain and the Membrane Regulate Transmembrane Signaling
2005
Prediction and structural characterization of an independently folding substructure in the src SH3 domain
1998 StandoutNobel
A series of point mutations reveal interactions between the calcium‐binding sites of calmodulin
1992
Solution structure of a zinc finger domain of yeast ADR1
1990
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex.
2001
Zinc-Dependent Structure of a Single-Finger Domain of Yeast ADR1
1988 Science
MyoD forms micelles which can dissociate to form heterodimers with E47: implications of micellization on function.
1995
Two-dimensional NMR investigation of a bent DNA fragment: assignment of the proton resonances and preliminary structure analysis
1987
1H NMR studies of calmodulin
1984
A Simple Method for the Refinement of Models Derived from NMR Data Demonstrated on a Zinc-Finger Domain from Yeast ADR1
1993
Solution Structure of the Sodium Channel Inactivation Gate,
1998
Mutations in mitochondrial histidyl tRNA synthetase HARS2 cause ovarian dysgenesis and sensorineural hearing loss of Perrault syndrome
2011
E2s: structurally economical and functionally replete
2010
1H‐NMR studies of calmodulin
1984
Interaction of calmodulin and a calmodulin-binding peptide from myosin light chain kinase: major spectral changes in both occur as the result of complex formation
1985 StandoutNobel
Influence of N-Cap Mutations on the Structure and Stability of Escherichia coli HPr
1996
The nature of the trifluoperazine binding sites on calmodulin and troponin-C
1984
Two-dimensional proton NMR studies of histidine-containing protein from Escherichia coli. 1. Sequential resonance assignments
1986
Spectroscopic studies of wild-type and mutant "zinc finger" peptides: determinants of domain folding and structure.
1990
Azidotyrosylcalmodulin derivatives. Specific probes for protein-binding domains.
1984
Recognition of DNA by Cys 2 ,His 2 Zinc Fingers
1991 Science