Citation Impact

Citing Papers

Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O 2 activation
2019 StandoutNobel
Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes
2013 Standout
Inhibitory effects of cupferron on the monophenolase and diphenolase activity of mushroom tyrosinase
2003
Improvement of poly(amphiphilic pyrrole) enzyme electrodes via the incorporation of synthetic laponite-clay-nanoparticles1
1997
Enzyme-controllable F-NMR turn on through disassembly of peptide-based nanospheres for enzyme detection
2014
Effect of captopril on mushroom tyrosinase activity in vitro
2001
Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation
1999 StandoutNatureNobel
Enzyme-Catalyzed Activation of Anticancer Prodrugs
2004
Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future
2005
Carbon–heteroatom bond formation catalysed by organometallic complexes
2008 StandoutNature
Redox behavior of melanins: direct electrochemistry of dihydroxyindole-melanin and its Cu and Zn adducts
2002
Biomimetic Modeling of Copper Complexes: A Study of Enantioselective Catalytic Oxidation on D‐(+)‐Catechin and L‐(−)‐Epicatechin with Copper Complexes
2008
Oxyresveratrol as the Potent Inhibitor on Dopa Oxidase Activity of Mushroom Tyrosinase
1998
Tyrosinase: a comprehensive review of its mechanism
1995 Standout
Crystallographic Evidence That the Dinuclear Copper Center of Tyrosinase Is Flexible during Catalysis
2006
Molecular Anatomy of Tyrosinase and its Related Proteins: Beyond the Histidine‐Bound Metal Catalytic Center
2002
Palladium(II)‐Catalyzed CH Activation/CC Cross‐Coupling Reactions: Versatility and Practicality
2009 Standout
A Self‐Sufficient Peroxide‐Driven Hydroxylation Biocatalyst
2003 StandoutNobel
Inactivation Kinetics of Mushroom Tyrosinase by Cetylpyridinium Chloride
2003
Evidence of the Indirect Formation of the Catecholic Intermediate Substrate Responsible for the Autoactivation Kinetics of Tyrosinase
1997
pH-Tunable Oxidase-Like Activity of Cerium Oxide Nanoparticles Achieving Sensitive Fluorigenic Detection of Cancer Biomarkers at Neutral pH
2011
Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion
2008 StandoutNature
Chemical and Instrumental Approaches to Treat Hyperpigmentation
2003 Standout
Inhibitory Effects of Some Flavonoids on the Activity of Mushroom Tyrosinase
2003
Melanogenesis and the Generation of Cytotoxic Molecules During Insect Cellular Immune Reactions
1993
Copper–O2 reactivity of tyrosinase models towards external monophenolic substrates: molecular mechanism and comparison with the enzyme
2011
Synthesis of N-substituted N-nitrosohydroxylamines as inhibitors of Mushroom Tyrosinase
2001
Biogenesis of Novel Quinone Coenzymes1
1995
Enzymatic functionalization of carbon–hydrogen bonds
2010 StandoutNobel
Survey and mechanism of skin depigmenting and lightening agents
2006
Irreversibly inhibitory kinetics of 3,5-dihydroxyphenyl decanoate on mushroom (Agaricus bisporus) tyrosinase
2005
Naturally occurring tyrosinase inhibitors: mechanism and applications in skin health, cosmetics and agriculture industries
2007
Functional interaction of diphenols with polyphenol oxidase
2007
Synthesis and antioxidant capacities of hydroxyl derivatives of cinnamoylphenethylamine in protecting DNA and scavenging radicals
2010
Electrochemical detection of DNA damage induced by acrylamide and its metabolite at the graphene-ionic liquid-Nafion modified pyrolytic graphite electrode
2011
Separating water isotopologues using diffusion-regulatory porous materials
2022 StandoutNatureNobel
3d Transition Metals for C–H Activation
2018 Standout
Direct electron transfer and electrocatalysis of microperoxidase immobilized on nanohybrid film
2005
Evidence Consistent with the Requirement of Cresolase Activity for Suicide Inactivation of Tyrosinase
2008
Geometric and Electronic Structure/Function Correlations in Non-Heme Iron Enzymes
1999 Standout
Graphene Oxide: Preparation, Functionalization, and Electrochemical Applications
2012 Standout
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
Multicopper Oxidases and Oxygenases
1996 Standout
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Site-Specific Bioconjugation through Enzyme-Catalyzed Tyrosine–Cysteine Bond Formation
2020 StandoutNobel
Structure and Spectroscopy of Copper−Dioxygen Complexes
2004 Standout
C-H Bond Functionalization in Complex Organic Synthesis
2006 StandoutScience
Copper Active Sites in Biology
2014 Standout
Recent Advances in Transition Metal Catalyzed Oxidation of Organic Substrates with Molecular Oxygen
2005 Standout
Inhibition of Carbonic Anhydrase II by Thioxolone: A Mechanistic and Structural Study
2008
Conjugated Polymer-Based Chemical Sensors
2000 Standout
The Mechanism of Suicide-Inactivation of Tyrosinase: A Substrate Structure Investigation
2007
Substrate share in the suicide inactivation of mushroom tyrosinase
2004
Bright Side of Lignin Depolymerization: Toward New Platform Chemicals
2018 Standout
Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope
2011 Standout
Studies on the electrochemical degradation of Acid Orange II wastewater with cathodes modified by quinones
2013
Palladium-Catalyzed Transformations of Alkyl C–H Bonds
2016 Standout
Two Potent Suicide Substrates of Mushroom Tyrosinase:  7,8,4‘-Trihydroxyisoflavone and 5,7,8,4‘-Tetrahydroxyisoflavone
2007
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
Kojic Acid, a Cosmetic Skin Whitening Agent, is a Slow-binding Inhibitor of Catecholase Activity of Tyrosinase
1994
Mushroom Tyrosinase:  Recent Prospects
2003
Polydopamine and Its Derivative Materials: Synthesis and Promising Applications in Energy, Environmental, and Biomedical Fields
2014 Standout
Gold Nanoparticles in Chemical and Biological Sensing
2012 Standout
The Chemistry and Biochemistry of Vanadium and the Biological Activities Exerted by Vanadium Compounds
2004 Standout
Competitive Inhibition of Mushroom Tyrosinase by 4-Substituted Benzaldehydes
2001
Aerobic Copper-Catalyzed Organic Reactions
2013 Standout
Single and Coupled Electrochemical Processes and Reactors for the Abatement of Organic Water Pollutants: A Critical Review
2015 Standout
Umbelliferone and Esculetin: Inhibitors or Substrates for Polyphenol Oxidases?
2008
An Updated Review of Tyrosinase Inhibitors
2009 Standout
Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization
2012 Standout
Organic Reactions in Aqueous Media with a Focus on Carbon−Carbon Bond Formations:  A Decade Update
2005 Standout
Activation of C−H Bonds by Metal Complexes
1997 Standout
Mechanisms Whereby Mononuclear Copper Proteins Functionalize Organic Substrates
1996 Standout
Dual Catalysis Strategies in Photochemical Synthesis
2016 Standout
Superoxide Ion: Generation and Chemical Implications
2016 Standout
The Host Defense of Drosophila melanogaster
2007 StandoutNobel
Biomimetic Modelling of Copper Enzymes: Synthesis, Characterization, EPR Analysis and Enantioselective Catalytic Oxidations by a New Chiral Trinuclear Copper(II) Complex
2008
4,4′-Dihydroxybiphenyl as a New Potent Tyrosinase Inhibitor
2005
Phenol oxidation by copper-metallated 9-allyladenine-DVB polymer: reaction catalysis and polymer recycling
2001
New Perspectives in the Chemistry and Biochemistry of the Tunichromes and Related Compounds
1997
Regulation of Melanin Synthesis by Selenium-Containing Carbohydrates
2006
Protein Radicals in Enzyme Catalysis
1998 Standout
Proton-Coupled Electron Transfer
2007
Selective oxidations catalyzed by peroxidases
1997
Isolation and Identification of Flavonoids in Licorice and a Study of Their Inhibitory Effects on Tyrosinase
2005
Direct C−H Transformation via Iron Catalysis
2010 Standout
Solar Synthesis: Prospects in Visible Light Photocatalysis
2014 StandoutScience
Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes
1998 StandoutNobel
Ru-, Rh-, and Pd-Catalyzed C−C Bond Formation Involving C−H Activation and Addition on Unsaturated Substrates:  Reactions and Mechanistic Aspects
2002 Standout
Enzymatic grafting of a natural product onto chitosan to confer water solubility under basic conditions
1999
Chitosan Chemistry and Pharmaceutical Perspectives
2004 Standout
Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions
2010 Standout
Inhibitory effects on mushroom tyrosinase by flavones from the stem barks ofMorus lhou(S.) Koidz
2008
Slow-Binding Inhibition of Mushroom (Agaricusbisporus) Tyrosinase Isoforms by Tropolone
1999
Potent Inhibitory Effects of N-Aryl S-Alkylthiocarbamate Derivatives on the Dopa Oxidase Activity of Mushroom Tyrosinase
2005
Carbon Dioxide Capture in Metal–Organic Frameworks
2011 Standout
Proton-Coupled Electron Transfer
2012 Standout
Inhibitory effects of salicylic acid family compounds on the diphenolase activity of mushroom tyrosinase
2005
In Situ Formation of an Oxygen-Evolving Catalyst in Neutral Water Containing Phosphate and Co 2+
2008 StandoutScience
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout

Works of R. Varón being referenced

Oxidation of 3,4-dihydroxymandelic acid catalyzed by tyrosinase
1988
Generation of hydrogen peroxide in the melanin biosynthesis pathway
2009
Kinetic characterization of the substrate specificity and mechanism of mushroom tyrosinase
2000
Kinetic study in the transient phase of the suicide inactivation of frog epidermis tyrosinase
1988
Kinetic study on the effect of pH on the melanin biosynthesis pathway
1991
Tyrosinase kinetics: discrimination between two models to explain the oxidation mechanism of monophenol and diphenol substrates
2003
A kinetic study on the suicide inactivation of peroxidase by hydrogen peroxide
1990
A Continuous Spectrophotometric Method for Determining the Monophenolase and Diphenolase Activities of Apple Polyphenol Oxidase
1995
Experimental Methods for Kinetic Study of Suicide Substrates
1989
Kinetic Characterization of Dopamine as a Suicide Substrate of Tyrosinase
1987
Interpretation of the reactivity of peroxidase compound II with phenols and anilines using the Marcus equation
2005
Catalytic oxidation of 2,4,5-trihydroxyphenylalanine by tyrosinase: identification and evolution of intermediates
1992
Tyrosinase inactivation in its action on dopa
2010
Catalytic oxidation of o-aminophenols and aromatic amines by mushroom tyrosinase
2011
The inactivation of horseradish peroxidase isoenzyme AZ by hydrogen peroxide: an example of partial resistance due to the formation of a stable enzyme intermediate
2001
Suicide inactivation of the diphenolase and monophenolase activities of tyrosinase
2010
Calculating molar absorptivities for quinones: Application to the measurement of tyrosinase activity
2006
Kinetic analysis of enzyme systems with suicide substrate in the presence of a reversible competitive inhibitor, tested by simulated progress curves
2001
Kinetic study of an enzyme-catalysed reaction in the presence of novel irreversible-type inhibitors that react with the product of enzymatic catalysis
1995
Kinetic characterisation of the reaction mechanism of mushroom tyrosinase on tyramine/dopamine and l-tyrosine methyl esther/l-dopa methyl esther
2002
Action Mechanism of Tyrosinase on meta- and para-Hydroxylated Monophenols
2000
The effect of pH on the suicide inactivation of frog epidermis tyrosinase
1994
Quantification of the Antioxidant Capacity of Different Molecules and Their Kinetic Antioxidant Efficiencies
2010
Monophenolase and Diphenolase Reaction Mechanisms of Apple and Pear Polyphenol Oxidases
1998
Effect of pH on the oxidation pathway of α-methyldopa catalysed by tyrosinase
1990
Kinetic Study of the Oxidation of Quercetin by Mushroom Tyrosinase
2003
A Review on Spectrophotometric Methods for Measuring the Monophenolase and Diphenolase Activities of Tyrosinase
2007
Analysis of a kinetic model for melanin biosynthesis pathway.
1992
Stopped-Flow and Steady-State Study of the Diphenolase Activity of Mushroom Tyrosinase
2000
Continuous Spectrophotometric Method for Determining Monophenolase and Diphenolase Activities of Pear Polyphenoloxidase
1996
Transient-phase kinetics of enzyme inactivation induced by suicide substrates
1987
Monophenolase activity of polyphenol oxidase from Verdedoncella apple
1995
Oxygen Michaelis constants for tyrosinase
1993
Characterization of Polyphenol Oxidase from Airen Grapes
1988
Reaction mechanism to explain the high kinetic autoactivation of tyrosinase
2005
Time-dependent inhibition of grape polyphenol oxidase by tropolone
1991
The inactivation of horseradish peroxidase by m-chloroperoxybenzoic acid, a xenobiotic hydroperoxide
1995
Kinetic study on the suicide inactivation of tyrosinase induced by catechol
1987
Analysis and interpretation of the action mechanism of mushroom tyrosinase on monophenols and diphenols generating highly unstable o-quinones
2001
Kinetic study of monophenol and o-diphenol binding to oxytyrosinase
2005
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