Standout Papers
Citation Impact
Citing Papers
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Pathophysiology of Migraine: A Disorder of Sensory Processing
2017 Standout
Spontaneous association between opioid receptors and GTP-binding regulatory proteins in native membranes: specific regulation by antagonists and sodium ions.
1990
Antidepressant Drug Effects and Depression Severity
2010 Standout
DECONSTRUCTING ENDOGENOUS PAIN MODULATIONS
2005
The neural basis of drug craving: An incentive-sensitization theory of addiction
1993 Standout
Merkel Cells Activate Sensory Neural Pathways through Adrenergic Synapses
2018 StandoutNobel
Modulation of anxiety through blockade of anandamide hydrolysis
2002 Standout
Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice
1999 StandoutNobel
Purinergic mechanisms in epilepsy
1988
Elicited hippocampal theta rhythm: a screen for anxiolytic and procognitive drugs through changes in hippocampal function?
2007
Descending noradrenergic influences on pain
1991
Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptor
1995 StandoutNatureNobel
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
Release of dopamine is reduced by diazepam more in the nucleus accumbens than in the caudate nucleus of conscious rats
1991
Why Does Social Exclusion Hurt? The Relationship Between Social and Physical Pain.
2005 Standout
Drugs, their targets and the nature and number of drug targets
2006
Mechanisms of Actions of Inhaled Anesthetics
2003 Standout
Serotonin and Nociception
1990
High doses of oxytocin cause sedation and low doses cause an anxiolytic-like effect in male rats
1994
DrugBank: a knowledgebase for drugs, drug actions and drug targets
2007 Standout
The putatively antipsychotic agent amperozide produces behavioural stimulation in the rat
1989 StandoutNobel
5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: More than 30 years of research
1995
Neurobiological Similarities in Depression and Drug Dependence: A Self-Medication Hypothesis
1998
Spinal serotonin receptors mediate descending facilitation of a nociceptive reflex from the nuclei reticularis gigantocellularis and gigantocellularis pars alpha in the rat
1991
Independence of benzodiazepine and opiate action in the suppression of isolation distress in rat pups.
1990
Reversal of pathological pain through specific spinal GABAA receptor subtypes
2008 Nature
Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+
1990 StandoutNobel
Synthesis and Release of Dopamine in Rat Brain: Comparison Between Substantia Nigra Pars Compacta, Pars Reticulata, and Striatum
1989 StandoutNobel
GABA A -receptors: Structural requirements and sites of gene expression in mammalian brain
1990
Novelty and Anxiolytic Drugs Dissociate Two Components of Hippocampal Theta in Behaving Rats
2013 StandoutNobel
Modulation of GABAA receptor desensitization uncouples sleep onset and maintenance in Drosophila
2008 StandoutNobel
Dorsal root potentials and dorsal root reflexes: a double-edged sword
1999
Delta-9-tetrahydrocannabinol-induced catalepsy in mice is enhanced by pretreatment with flurazepam or chlordiazepoxide
1988
Blockade of the picrotoxin-induced in vivo release of dopamine in the cat caudate nucleus by diazepam
1977
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Methodological aspects for in vitro characterization of receptor binding using 11C-labeled receptor ligands: A detailed study with the benzodiazepine receptor antagonist [11C]Ro 15-1788
1997
Pindolol antagonizes the effects on hippocampal rhythmical slow activity of clonidine, baclofen and 8-OH-DPAT, but not chlordiazepoxide and sodium amylobarbitone
1992
A Novel Subtype of Prostacyclin Receptor in the Central Nervous System
1999 StandoutNobel
Evidence for a role for dopamine in the diazepam locomotor stimulating effect
1991
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Functional properties of recombinant rat GABAA receptors depend upon subunit composition
1990 StandoutNobel
Major Depressive Disorder
2008 Standout
Socially mediated reduction of isolation distress in rat pups is blocked by naltrexone but not by Ro 15-1788.
1990
The biopsychosocial approach to chronic pain: Scientific advances and future directions.
2007 Standout
GABAergic dysfunction in mood disorders
2003
Molecular Basis of Buspirone's Anxiolytic Action
1991
Interneuronal relay in spinal pathways from proprioceptors
1992
A Controlled Trial of Riluzole in Amyotrophic Lateral Sclerosis
1994 Standout
Artificial intelligence in radiology
2018 Standout
Brainstem modulation of pain during sleep and waking
2003
Controlled Microwave Heating in Modern Organic Synthesis
2004 Standout
The diversity of GABAA receptors
1998
Selective and non-selective inhibition by enkephalins and noradrenaline of nociceptive response of lamina V type neurons in the spinal dorsal horn of the rabbit
1979
Iron Catalysis in Organic Synthesis
2015 Standout
Iron(III)-catalyzed synthesis of multi-substituted imidazoles via [3+2] cycloaddition reaction of nitroolefins and N-aryl benzamidines
2013
Rat pup ultrasonic isolation calls: Possible mediation by the benzodiazepine receptor complex
1986
Are benzodiazepines GABA antagonists?
1977 Nature
Structural and functional characterization of the gamma 1 subunit of GABAA/benzodiazepine receptors.
1990
‘Inverse agonists’, cooperativity and drug action at benzodiazepine receptors
1986
A Double-blind Comparative Trial of Moclobemide v. Imipramine and Placebo in Major Depressive Episodes
1989
Pharmacological interventions for somatoform disorders in adults
2014 Standout
5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system.
1989 StandoutNobel
Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology
1989 StandoutNature
The 5-HT3Subtype of Serotonin Receptor Contributes to Nociceptive Processing via a Novel Subset of Myelinated and Unmyelinated Nociceptors
2002 StandoutNobel
Urinary and brain beta-carboline-3-carboxylates as potent inhibitors of brain benzodiazepine receptors.
1980 Standout
Specificity of GABA as a stimulator of dopamine release in rat substantia nigra
1980
Physiological Identification of Pontomedullary Serotonergic Neurons in the Rat
1997
Effect of Nitrous Oxide on Excitatory and Inhibitory Synaptic Transmission in Hippocampal Cultures
1998
Pharmacological characterization of benzodiazepine receptors in the brain
1978
Descending projections of the locus coeruleus and subcoeruleus/medial parabrachial nuclei in monkey: Axonal transport studies and dopamine-β-hydroxylase immunocytochemistry
1980
Early Exposure to Common Anesthetic Agents Causes Widespread Neurodegeneration in the Developing Rat Brain and Persistent Learning Deficits
2003 Standout
Dopamine autoreceptors and the effects of drugs on locomotion and dopamine synthesis
1985 StandoutNobel
Spinal and Supraspinal Factors in Human Muscle Fatigue
2001 Standout
Interaction of Convulsive Ligands with Benzodiazepine Receptors
1982 StandoutScience
Drug Discovery: A Historical Perspective
2000 StandoutScience
Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.
1988 Standout
The neuropsychology and neuropharmacology of the dorsal ascending noradrenergic bundle—a review
1980
Cellular and Molecular Mechanisms of Drug Dependence
1988 StandoutScience
Synthesis of imidazole-4-carboxylic acids via solid-phase bound 3-N,N-(dimethylamino)-2-isocyanoacrylate
2004
Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding.
1977
Antinociceptive Action of Nitrous Oxide Is Mediated by Stimulation of Noradrenergic Neurons in the Brainstem and Activation of α2BAdrenoceptors
2000 StandoutNobel
Prolactin: Structure, Function, and Regulation of Secretion
2000 Standout
The Benzodiazepine Receptor in Normal and Pathological Human Brain
1978
Genetic contributions to generalized arousal of brain and behavior
2003 StandoutNobel
Fatal Familial Insomnia and Dysautonomia with Selective Degeneration of Thalamic Nuclei
1986
Spinal noradrenergic terminal system mediates antinociception
1980
2-Amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission—I
1985
Microinjection of morphine into the periaqueductal gray evokes the release of serotonin from spinal cord
1979
The effects of FG 7142 and RO 15-1788 on the release of punished responding produced by chlordiazepoxide and ethanol in the rat
1986
Relative contributions of the nucleus raphe magnus and adjacent medullary reticular formation to the inhibition by stimulation in the periaqueductal gray of a spinal nociceptive reflex in the pentobarbital-anesthetized rat
1984
Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study
1991 Standout
Postsynaptic inhibition of primate spinothalamic neurons by stimulation in nucleus raphe magnus
1981
The Oxytocin Receptor System: Structure, Function, and Regulation
2001 Standout
Benzodiazepine- and barbiturate-interactions with GABAA receptor responses on lactotrophes
1986
Norepinephrine reduces excitability of single cutaneous primary afferent C-fibers in the cat spinal cord
1981
Nucleus locus ceruleus: new evidence of anatomical and physiological specificity
1983 Standout
Serotonin receptor knockouts: A moody subject
1998 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region
1996 StandoutScience
An opioid benzodiazepine
1982 Nature
On the mode of action of diazepam on brain catecholamine metabolism
1978 StandoutNobel
Inherited prion diseases.
1994 StandoutNobel
Endogenous ligands for benzodiazepine recognition sites
1985
Diazepam and chlordiazepoxide: powerful GABA antagonists in explants of rat cerebellum
1976
Behavioural responses induced by intrathecal injection of 5-hydroxytryptamine in mice are inhibited by a substance P antagonist, -Pro2,-Trp7,9-substance P
1983
Reversal of the anti-conflict action of valproate by various GABA and benzodiazepine antagonists
1984
Works of R. Schaffner being referenced
Ro 15-4513: Partial inverse agonism at the BZR and interaction with ethanol
1988
Pharmacological profile of moclobemide, a short-acting and reversible inhibitor of monoamine oxidase type A.
1989
Benzodiazepines and GABA
1976 Nature
Pharmacology of midazolam.
1981
Possible involvement of GABA in the central actions of benzodiazepines.
1975
A three-state model of the benzodiazepine receptor explains the interactions between the benzodiazepine antagonist Ro 15-1788, benzodiazepine tranquilizers, ?-carbolines, and phenobarbitone
1982
Benzodiazepine antagonist Ro 15-1788: Neurological and behavioral effects
1982
Some neuropharmacological effects of Ro 11-2465--a novel tricyclic antidepressant with potent inhibitory activity on the uptake of 5-HT.
1982
The differential effects of 5-hydroxytryptamine, noradrenaline and raphe stimulation on nociceptive and non-nociceptive dorsal horn interneurones in the cat
1978
Interaction of benzodiazepines with neuroleptics at central dopamine neurons
1976
Pharmacology of moclobemide.
1993
Selective antagonists of benzodiazepines
1981 StandoutNature