Citation Impact
Citing Papers
Identification of autophosphorylation sites of HER2/neu.
1990
Involvement of pp60c-src with two major signaling pathways in human breast cancer.
1994
Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body
1990
1002 Protein Phosphatases?
1992
Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice
1988 StandoutNobel
The Cold Shock Domain Protein LIN-28 Controls Developmental Timing in C. elegans and Is Regulated by the lin-4 RNA
1997 StandoutNobel
Signal transduction by receptors with tyrosine kinase activity
1990 Standout
Purification and characterization of a human recombinant T-cell protein-tyrosine-phosphatase from a baculovirus expression system
1991 StandoutNobel
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor
1989 Nature
Novel putative receptor tyrosine kinase encoded by the melanoma-inducing Tu locus in Xiphophorus
1989 Nature
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Nopp 140 shuttles on tracks between nucleolus and cytoplasm
1992 StandoutNobel
Signal Transduction in Hamster Fibroblasts Overexpressing the Human EGF Receptor
1989
A highly conserved tyrosine residue at codon 845 within the kinase domain is not required for the transforming activity of human epidermal growth factor receptor
1992
Multiple intercellular signalling systems control the development of the Caenorhabditis elegans vulva
1991 StandoutNatureNobel
An Open-and-Shut Case? Recent Insights into the Activation of EGF/ErbB Receptors
2003
Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
1989 Standout
Crystal Structure of the Complex of Human Epidermal Growth Factor and Receptor Extracellular Domains
2002
Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides
1992 NatureNobel
TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice
1993 StandoutNobel
Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes
1988 StandoutNatureNobel
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins
1998 StandoutNatureNobel
Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template
2004 StandoutNatureNobel
LITHIUM AND MAGNESIUM-DEPENDENT ENZYMES
1974
Protein Tyrosine Phosphatases: A Diverse Family of Intracellular and Transmembrane Enzymes
1991 Science
Glucocorticoid-receptor interaction and induction of murine mammary tumor virus.
1975
Mapping unintegrated avian sarcoma virus DNA: Termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNA
1978 StandoutNobel
Generation of transforming growth factor-alpha from the cell surface by an O-glycosylation-independent multistep process.
1990
Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus
1983 StandoutNobel
Transforming growth factor-α in the mammalian brain
1989
Serotonin-Mediated Endocytosis of apCAM: an Early Step of Learning-Related Synaptic Growth in Aplysia
1992 StandoutScienceNobel
Interaction Between Viral and Genetic Factors in Murine Mammary Cancer
1978
Size and Genetic Content of Viral RNAs in Avian Oncovirus-Infected Cells
1977
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain
1986 StandoutNobel
Signal transduction by fibroblast growth factor receptor-4 (FGFR-4). Comparison with FGFR-1
1994
Analysis of avian leukosis virus DNA and RNA in bursal tumors: Viral gene expression is not required for maintenance of the tumor state
1981 StandoutNobel
High frequency of aberrant expression of moloney murine leukemia virus in clonal infections
1978 Nobel
Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling
2010
clr-1 encodes a receptor tyrosine phosphatase that negatively regulates an FGF receptor signaling pathway in Caenorhabditis elegans
1998 StandoutNobel
A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1.
1991
Epidermal Growth Factor (EGF)-induced Generation of Hydrogen Peroxide
1997 Standout
The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes
1981 Nature
Analysis of two divergent rat genomic clones homologous to the transforming gene of Harvey murine sarcoma virus.
1981
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
THE GENETIC STRUCTURE OF RNA TUMOR VIRUSES
1977
Low Molecular Weight Deoxyribonucleic Acid Polymerase in Mammalian Cells
1971
Mammary tumor virus induction by glucocorticoids. Characterization of specific transcriptional regulation.
1975
Transformation by murine and feline sarcoma viruses specifically blocks binding of epidermal growth factor to cells
1976 StandoutNatureNobel
Location and function of retroviral and SV40 sequences that enhance biochemical transformation after microinjection of DNA
1983 StandoutNobel
Dexamethasone-mediated induction of mouse mammary tumor virus RNA: a system for studying glucocorticoid action
1975 StandoutNobel
Transformation of Immature Lymphoid Cells by Abelson Murine Leukemia Virus
1979 Nobel
Specific RNA sequences and gene products of MC29 avian acute leukemia virus
1978
Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog
1987 StandoutNobel
Complementation of the Mitotic Activator, p80 cdc25 , by a Human Protein-tyrosine Phosphatase
1990 StandoutScienceNobel
Epidermal growth factor binding induces a conformational change in the external domain of its receptor.
1989
Functional organization of the Harvey murine sarcoma virus genome
1980
Structural Characterization and Biological Functions of Fibroblast Growth Factor
1987
Characterization and cDNA Cloning of Phospholipase C-γ, a Major Substrate for Heparin-Binding Growth Factor 1 (Acidic Fibroblast Growth Factor)-Activated Tyrosine Kinase
1990
Expression of a human T-cell protein-tyrosine-phosphatase in baby hamster kidney cells.
1990
Cytoplasmic domains determine signal specificity, cellular routing characteristics and influence ligand binding of epidermal growth factor and insulin receptors.
1989
Correct integration of retroviral DNA in vitro
1987 StandoutNobel
Recovery of avian sarcoma virus from tumors induced by transformation-defective mutants.
1977
Long terminal repeat sequences impart hematopoietic transformation properties to the myeloproliferative sarcoma virus.
1985
Molecular basis for multimerization in the activation of the epidermal growth factor receptor
2016
Multiple RNAs expressed from the int-2 gene in mouse embryonal carcinoma cell lines encode a protein with homology to fibroblast growth factors.
1988
Molecular biology: Reverse transcriptase rides again
1985 StandoutNatureNobel
A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells
1983 StandoutNatureNobel
A novel ras-related gene family
1985 StandoutNobel
Identification of nuclear proteins encoded by viral and cellular myc oncogenes
1983 StandoutNatureNobel
Dual evolutionary origin for the rat genetic sequences of Harvey murine sarcoma virus
1980
A Tyrosine-Phosphorylated Carboxy-Terminal Peptide of the Fibroblast Growth Factor Receptor (Flg) Is a Binding Site for the SH2 Domain of Phospholipase C-γ1
1991
Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector
1986 StandoutNatureNobel
Stable expression of truncated inositol 1,4,5-trisphosphate receptor subunits in 3T3 fibroblasts. Coordinate signaling changes and differential suppression of cell growth and transformation.
1994 StandoutNobel
The receptor-like protein tyrosine phosphatase HPTP alpha has two active catalytic domains with distinct substrate specificities.
1991
Activation of the c-mos oncogene in a mouse plasmacytoma by insertion of an endogenous intracisternal A-particle genome.
1983
Isolation and characterization of chicken DNA homologous to the two putative oncogenes of avian erythroblastosis virus
1982 StandoutNobel
Structure and specific sequences of avian erythroblastosis virus RNA: Evidence for multiple classes of transforming genes among avian tumor viruses
1979
Tyrosine kinase activity is essential for the association of phospholipase C-gamma with the epidermal growth factor receptor.
1990
Virus-Like 30S RNA in Mouse Cells
1979 Nobel
Harvey ras genes transform without mutant codons, apparently activated by truncation of a 5' exon (exon -1).
1986
Properties of a Normal Mouse Cell DNA Sequence (sarc) Homologous to the src Sequence of Moloney Sarcoma Virus
1980 Science
DETECTION OF HERPES-SIMPLEX VIRAL GENOME IN BRAIN TISSUE
1979
A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA
1985 StandoutNobel
Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen
1989 StandoutScience
A potential animal model for Lesch–Nyhan syndrome through introduction of HPRT mutations into mice
1987 StandoutNatureNobel
Angiogenic Factors
1987 StandoutScience
Transforming growth factor-alpha. A model for membrane-anchored growth factors.
1990
Characterization of a human recombinant receptor-linked protein tyrosine phosphatase
1991 StandoutNobel
Reactions at the 3' Terminus of Transfer Ribonucleic Acid
1970
Deoxyribonucleic acid polymerase with rat liver ribosomes and smooth membranes. Purification and properties of the enzyme
1971
Mammary Tumor Viruses
1979
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
In Vitro Enzymatic Characterization of Near Full Length EGFR in Activated and Inhibited States
2009
Receptor for acidic fibroblast growth factor is related to the tyrosine kinase encoded by the fms-like gene (FLG).
1989
Four classes of mRNA are expressed from the mouse int-2 gene, a member of the FGF gene family.
1988
Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein
1978 StandoutNobel
Characterization and cDNA cloning of phospholipase C-gamma, a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.
1990
Purification and Properties of Nuclear and Cytoplasmic Deoxyribonucleic Acid Polymerases from Human KB Cells
1972
Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas
1982 StandoutNatureNobel
Homology between human bladder carcinoma oncogene product and mitochondrial ATP-synthase
1983 StandoutNatureNobel
The catalytic activity of the CD45 membrane-proximal phosphatase domain is required for TCR signaling and regulation.
1994
DNA biosynthesis in mitochondria: partial purification of a distinct DNA polymerase from isolated rat liver mitochondria.
1968
Cloning, bacterial expression, purification, and characterization of the cytoplasmic domain of rat LAR, a receptor-like protein tyrosine phosphatase.
1991
Sindbis Virus: An Efficient, Broad Host Range Vector for Gene Expression in Animal Cells
1989 StandoutScienceNobel
Nucleotide sequence and formation of the transforming gene of a mouse sarcoma virus
1981 Nature
Immunoglobulin Gene Rearrangement in Immature B Cells
1980 StandoutScienceNobel
Nucleotide sequence of Moloney murine leukaemia virus
1981 Nature
Isolation of virus from brain after immunosuppression of mice with latent herpes simplex
1981 StandoutNatureNobel
Cloning of integrated Moloney sarcoma proviral DNA sequences in bacteriophage lambda.
1979
Evidence for epidermal growth factor (EGF)-induced intermolecular autophosphorylation of the EGF receptors in living cells.
1990
Activation of the kinase Pelle by Tube in the dorsoventral signal transduction pathway of Drosophila embryo
1994 StandoutNatureNobel
Epidermal growth factor and transforming growth factor-alpha: differential intracellular routing and processing of ligand-receptor complexes.
1991
Nomenclature of Eukaryotic DNA Polymerases
1975 StandoutScienceNobel
Conformation of free and of integrated Moloney leukemia virus proviral DNA in preleukemic and leukemic BALB/Mo mice
1980
Internalization and down-regulation of the human epidermal growth factor receptor are regulated by the carboxyl-terminal tyrosines
1991
Evidence for protein-tyrosine-phosphatase catalysis proceeding via a cysteine-phosphate intermediate.
1991
Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture
1985 StandoutNatureNobel
Characterization of Moloney murine leukemia virus mutants with single-amino-acid substitutions in the Cys-His box of the nucleocapsid protein
1989
Works of R. Howk being referenced
Friend strain of spleen focus-forming virus is a recombinant between ecotropic murine type C virus and the env gene region of xenotropic type C virus.
1977
Identification of a 30S RNA with properties of a defective type C virus in murine cells
1978
All Autophosphorylation Sites of Epidermal Growth Factor (EGF) Receptor and HER2/neu Are Located in Their Carboxyl-terminal Tails
1989
Immunochemical Characterization of Two Major Polypeptides from Murine Mammary Tumor Virus
1974
Separation of sarcoma virus-specific and leukemia virus-specific genetic sequences of Moloney sarcoma virus.
1975
Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases expressed in brain.
1990
Defective retrovirus-like 30S RNA species of rat and mouse cells are infectious if packaged by type C helper virus
1979
A comparison of the transcription of mouse cell chromatin by homologous RNA polymerase I and II
1974
Partial Purification of a DNA-polymerase from the Non-histone Chromatin Proteins of Rat Liver
1967 Nature
Chicken epidermal growth factor (EGF) receptor: cDNA cloning, expression in mouse cells, and differential binding of EGF and transforming growth factor alpha.
1988
Deletion mapping of moloney type C virus: polypeptide and nucleic acid expression in different transforming virus isolates
1976
Chicken Epidermal Growth Factor (EGF) Receptor: cDNA Cloning, Expression in Mouse Cells, and Differential Binding of EGF and Transforming Growth Factor Alpha
1988
Functional analysis of the ligand binding site of EGF-receptor utilizing chimeric chicken/human receptor molecules.
1989
Human Endothelial Cell Growth Factor: Cloning, Nucleotide Sequence, and Chromosome Localization
1986 Science
Characterization and Separation of Viral DNA Polymerase in Mouse Milk
1973
Isolation of a New Simian Foamy Virus from a Spider Monkey Brain Culture
1973 StandoutNobel
DNA polymerase from rat liver chromosomal proteins I. Partial purification and general characteristics
1969