Citation Impact
Citing Papers
Antiseptics and Disinfectants: Activity, Action, and Resistance
1999 Standout
Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet
2009 Standout
Endocrine Disruptors and Asthma-Associated Chemicals in Consumer Products
2012 Standout
Epidemiology of and Diagnostic Strategies for Toxoplasmosis
2012 Standout
Chagas disease
2010 Standout
The gut microbiota and host health: a new clinical frontier
2015 Standout
Heavy metals in food crops: Health risks, fate, mechanisms, and management
2019 Standout
Consumption of Seafood, Serum Liver Enzymes, and Blood Levels of PFOS and PFOA in the Japanese Population
2013
Two-generation reproduction and cross-foster studies of perfluorooctanesulfonate (PFOS) in rats
2005
Relevance of Lung Ultrasound in the Diagnosis of Acute Respiratory Failure*: The BLUE Protocol
2008 Standout
Determination of perfluorinated alkyl acid concentrations in human serum and milk standard reference materials
2009
Negative bias from analog methods used in the analysis of free thyroxine in rat serum containing perfluorooctanesulfonate (PFOS)
2007
Associations between longitudinal serum perfluoroalkyl substance (PFAS) levels and measures of thyroid hormone, kidney function, and body mass index in the Fernald Community Cohort
2018
Mitochondrial Permeability Transition as the Critical Target of N-Acetyl Perfluorooctane Sulfonamide Toxicity in Vitro
2004
Community Exposure to Perfluorooctanoate: Relationships Between Serum Levels and Certain Health Parameters
2006
National Screening Study on 10 Perfluorinated Compounds in Raw and Treated Tap Water in France
2012
Perfluorinated chemicals in relation to other persistent organic pollutants in human blood
2006
Adsorption behavior and mechanism of perfluorinated compounds on various adsorbents—A review
2014 Standout
Impacts of soil and water pollution on food safety and health risks in China
2015 Standout
Effects of perfluorooctanoic acid on mouse mammary gland development and differentiation resulting from cross-foster and restricted gestational exposures
2008
Emerging organic contaminants in groundwater: A review of sources, fate and occurrence
2012 Standout
A short review on human exposure to and tissue distribution of per- and polyfluoroalkyl substances (PFASs)
2018
An oral two-generation reproductive toxicity study of S-111-S-WB in rats
2007
Mycobacterium avium and Mycobacterium intracellulare Infections in Patients with and without AIDS
1989
Analysis of per- and polyfluorinated alkyl substances in air samples from Northwest Europe
2007
Chagas cardiomyopathy: Europe is not spared!
2008
A comparison of the pharmacokinetics of perfluorobutanesulfonate (PFBS) in rats, monkeys, and humans
2008
Determination of perfluorooctanoic acid (PFOA) extractable from the surface of commercial cookware under simulated cooking conditions by LC/MS/MS
2005
Effects of prenatal perfluorooctane sulfonate (PFOS) exposure on lung maturation in the perinatal rat
2005
The gut microbiota, bacterial metabolites and colorectal cancer
2014 Standout
Gene expression profiling in the lung and liver of PFOA-exposed mouse fetuses
2007
Preliminary evidence of a decline in perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) concentrations in American Red Cross blood donors
2007
Time trends of perfluorinated compounds from the sediment core of Tokyo Bay, Japan (1950s–2004)
2009
Neglected Infections of Poverty in the United States of America
2008
Perfluoroalkyl Acids: A Review of Monitoring and Toxicological Findings
2007 Standout
Subacute exposure to N-ethyl perfluorooctanesulfonamidoethanol results in the formation of perfluorooctanesulfonate and alters superoxide dismutase activity in female rats
2009
Perfluorooctanoate: Placental and lactational transport pharmacokinetics in rats
2005
Antibiotics in the aquatic environment – A review – Part I
2009 Standout
Changes in serum levels of perfluoroalkyl substances during a 10-year follow-up period in a large population-based cohort
2016
Do perfluoroalkyl substances affect metabolic function and plasma lipids?—Analysis of the 2007–2009, Canadian Health Measures Survey (CHMS) Cycle 1
2012
Global emission inventories for C4–C14 perfluoroalkyl carboxylic acid (PFCA) homologues from 1951 to 2030, part II: The remaining pieces of the puzzle
2014
Per- and polyfluoroalkyl substance (PFAS) exposure assessment in a community exposed to contaminated drinking water, New Hampshire, 2015
2018
Persistent organic pollutants and male reproductive health
2014
Mitogen-activated protein kinase pathways
1997 Standout
Effects of Perfluorooctanoic Acid Exposure during Pregnancy in the Mouse
2006
Exposure to the Immunosuppresant, Perfluorooctanoic Acid, Enhances the Murine IgE and Airway Hyperreactivity Response to Ovalbumin
2007
Perfluorooctanoic Acid Induced Developmental Toxicity in the Mouse is Dependent on Expression of Peroxisome Proliferator Activated Receptor-alpha
2007
Associations between Perfluoroalkyl acids (PFASs) and maternal thyroid hormones in early pregnancy: A population-based cohort study
2014
PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling
2017
A pilot study on the determination of perfluorooctanesulfonate and other perfluorinated compounds in blood of Canadians
2004
Longitudinal Study of Serum Lipids and Liver Enzymes in Workers With Occupational Exposure to Ammonium Perfluorooctanoate
2007
Polyfluoroalkyl chemicals in house dust
2009
Analysis of Episodes of Care in a Perfluorooctanesulfonyl Fluoride Production Facility
2004
Gestational PFOA Exposure of Mice is Associated with Altered Mammary Gland Development in Dams and Female Offspring
2006
Characterization of risk for general population exposure to perfluorooctanoate
2004
Diet and particularly seafood are major sources of perfluorinated compounds in humans
2010
Developmental Toxicity of Perfluorooctanoic Acid in the CD-1 Mouse after Cross-Foster and Restricted Gestational Exposures
2006
Colorectal cancer
2013 Standout
Recent developments in photocatalytic water treatment technology: A review
2010 Standout
Elimination kinetics of perfluorohexanoic acid in humans and comparison with mouse, rat and monkey
2013
Perfluoroalkyl substances and bone health in young men: a pilot study
2019
Development and characterization of a solvent extraction–gas chromatographic/mass spectrometric method for the analysis of perfluorooctanesulfonamide compounds in solid matrices
2005
Perfluorinated organic compounds in human blood serum and seminal plasma: a study of urban and rural tea worker populations in Sri Lanka
2005
Induction of cardiac autoimmunity in Chagas heart disease: A case for molecular mimicry
2006
Review of ‘emerging’ organic contaminants in biosolids and assessment of international research priorities for the agricultural use of biosolids
2010
N-GLUCURONIDATION OF PERFLUOROOCTANESULFONAMIDE BY HUMAN, RAT, DOG, AND MONKEY LIVER MICROSOMES AND BY EXPRESSED RAT AND HUMAN UDP-GLUCURONOSYLTRANSFERASES
2006
Clinical Importance of Streptococcus gallolyticus Infection Among Colorectal Cancer Patients: Systematic Review and Meta-analysis
2011
Historical and geographical aspects of the increasing perfluorooctanoate and perfluorooctane sulfonate contamination in human serum in Japan
2006
Age effect on perfluorooctanoate (PFOA) plasma concentration in post-weaning rats following oral gavage with ammonium perfluorooctanoate (APFO)
2006
Influenza Vaccine Response in Adults Exposed to Perfluorooctanoate and Perfluorooctanesulfonate
2013
Chagas disease and stroke
2010
Occurrence of perfluorinated substances in an adult German population in southern Bavaria
2006
Concentrations of perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) and their associations with human semen quality measurements
2011
The developmental toxicity of perfluoroalkyl acids and their derivatives
2004
Influence of exposure to perfluoroalkyl substances (PFASs) on the Korean general population: 10-year trend and health effects
2018
Acute respiratory distress syndrome
2019 Standout
Half-lives of PFOS, PFHxS and PFOA after end of exposure to contaminated drinking water
2017
Perfluorooctanoic acid (PFOA), an emerging drinking water contaminant: A critical review of recent literature
2012
Perfluorinated compounds are related to breast cancer risk in greenlandic inuit: A case control study
2011
Renal clearance of perfluorooctane sulfonate and perfluorooctanoate in humans and their species-specific excretion
2005
Bladder Cancer in Perfluorooctanesulfonyl Fluoride Manufacturing Workers
2007
Chagas disease and the US blood supply
2008
Prenatal Perfluorooctanoic Acid Exposure in CD-1 Mice: Low-Dose Developmental Effects and Internal Dosimetry
2011
The reproductive toxicology of ammonium perfluorooctanoate (APFO) in the rat
2004
Community Exposure to Perfluorooctanoate: Relationships Between Serum Concentrations and Exposure Sources
2006
Neonatal mortality from in utero exposure to perfluorooctanesulfonate (PFOS) in Sprague–Dawley rats: Dose–response, and biochemical and pharamacokinetic parameters
2005
Occurrence and fate of emerging contaminants in municipal wastewater treatment plants from different geographical regions-a review
2017 Standout
Comparison of human whole blood, plasma, and serum matrices for the determination of perfluorooctanesulfonate (PFOS), perfluorooctanoate (PFOA), and other fluorochemicals
2006
Review of antibiotic resistance in China and its environment
2017 Standout
Serum concentrations of perfluorooctanesulfonate and other fluorochemicals in an elderly population from Seattle, Washington
2003
Perfluorinated compounds – Exposure assessment for the general population in western countries
2008
Perfluoroalkyl Acids and Related Chemistries—Toxicokinetics and Modes of Action
2007
Cumulative health risk assessment of 17 perfluoroalkylated and polyfluoroalkylated substances (PFASs) in the Swedish population
2013
Absorption, Distribution, Metabolism, and Elimination of 8-2 Fluorotelomer Alcohol in the Rat
2006
Chagas Heart Disease Pathogenesis: One Mechanism or Many?
2008
Perfluorinated Compounds and Subfecundity in Pregnant Women
2011
Preliminary observations on perfluorinated compounds in plasma samples (1977–2004) of young German adults from an area with perfluorooctanoate-contaminated drinking water
2008
Perfluorinated chemicals in blood of residents in Catalonia (Spain) in relation to age and gender: A pilot study
2007
Some issues relating to the use of perfluorooctanesulfonate (PFOS) samples as reference standards
2007
Occurrence of perfluorosulfonates and other perfluorochemicals in dust from selected homes in the city of Ottawa, Canada
2005
Physico-chemical properties and gestational diabetes predict transplacental transfer and partitioning of perfluoroalkyl substances
2019
Perfluorinated chemicals in selected residents of the American continent
2005
Synthesis of environmentally relevant fluorinated surfactants—a review
2005
The itinerary of Streptococcus gallolyticus infection in patients with colonic malignant disease
2013
Transplacental exposure of neonates to perfluorooctanesulfonate and perfluorooctanoate: a pilot study
2007
Decomposition kinetics of perfluorinated sulfonic acids
2019
Cross-Sectional Study of Lipids and Liver Enzymes Related to a Serum Biomarker of Exposure (ammonium perfluorooctanoate or APFO) as Part of a General Health Survey in a Cohort of Occupationally Exposed Workers
2007
Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment
2013 Standout
Genetic Diversity among Strains of Mycobacterium avium Causing Monoclonal and Polyclonal Bacteremia in Patients with AIDS
1993
Multiplicity of nuclear receptor activation by PFOA and PFOS in primary human and rodent hepatocytes
2011
Chagas Cardiomyopathy: An Update of Current Clinical Knowledge and Management: A Scientific Statement From the American Heart Association
2018
Analysis of PFOA in dosed CD-1 mice. Part 2: Disposition of PFOA in tissues and fluids from pregnant and lactating mice and their pups
2009
Evaluation and Treatment of Chagas Disease in the United States
2007
PFOS or PreFOS? Are perfluorooctane sulfonate precursors (PreFOS) important determinants of human and environmental perfluorooctane sulfonate (PFOS) exposure?
2010
A bacterial driver–passenger model for colorectal cancer: beyond the usual suspects
2012
Pilot study on the perfluorooctanesulfonate and perfluorooctanoate exposure of the German general population
2006
Fusobacterium nucleatum — symbiont, opportunist and oncobacterium
2018 Standout
Pharmacokinetics of Perfluorooctanoate in Cynomolgus Monkeys
2004
An Official ATS/IDSA Statement: Diagnosis, Treatment, and Prevention of Nontuberculous Mycobacterial Diseases
2007 Standout
The Toxicology of Perfluorooctanoate
2004
2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association
2021 Standout
Biological Monitoring of Polyfluoroalkyl Substances: A Review
2006 Standout
Factors Influencing Numbers of Mycobacterium avium , Mycobacterium intracellulare , and Other Mycobacteria in Drinking Water Distribution Systems
2001
Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing
1995 Standout
EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals
2015 Standout
Environmental Mass Spectrometry: Emerging Contaminants and Current Issues
2010
Exposure Assessment and Risk Characterization for Perfluorooctanoate in Selected Consumer Articles
2005
Exploring the Use of Molecular Docking to Identify Bioaccumulative Perfluorinated Alkyl Acids (PFAAs)
2015
Dietary Habits Related to Food Packaging and Population Exposure to PFASs
2019
Clinical review: Early treatment of acute lung injury - paradigm shift toward prevention and treatment prior to respiratory failure
2012
Sorption of Perfluorinated Surfactants on Sediments
2006 Standout
Levels of 12 Perfluorinated Chemicals in Pooled Australian Serum, Collected 2002−2003, in Relation to Age, Gender, and Region
2006
Polyfluoroalkyl Compounds in Free-Ranging Bottlenose Dolphins (Tursiops truncatus) from the Gulf of Mexico and the Atlantic Ocean
2005
Plasma Concentrations of Perfluoroalkyl Substances and Risk of Type 2 Diabetes: A Prospective Investigation among U.S. Women
2018
A Pilot Survey of Legacy and Current Commercial Fluorinated Chemicals in Human Sera from United States Donors in 2009
2011
Predicting Relative Protein Affinity of Novel Per- and Polyfluoroalkyl Substances (PFASs) by An Efficient Molecular Dynamics Approach
2018
Perfluorooctanesulfonate and Related Fluorochemicals in Human Blood Samples from China
2005
Water Analysis: Emerging Contaminants and Current Issues
2014 Standout
Investigation of binding and activity of perfluoroalkyl substances to the human peroxisome proliferator-activated receptor β/δ
2019
A review of transfusion practice before, during, and after hematopoietic progenitor cell transplantation
2008
Historical Comparison of Perfluorooctanesulfonate, Perfluorooctanoate, and Other Fluorochemicals in Human Blood
2005
Bacterial Biofilms: An Emerging Link to Disease Pathogenesis
2003 Standout
Polyfluoroalkyl Chemicals in Pooled Blood Serum from Infants, Children, and Adults in Australia
2009
Identification of Unsaturated and 2H Polyfluorocarboxylate Homologous Series and Their Detection in Environmental Samples and as Polymer Degradation Products
2015
Perfluorinated Carboxylic Acids in Directly Fluorinated High-Density Polyethylene Material
2011
Time Trends and the Influence of Age and Gender on Serum Concentrations of Perfluorinated Compounds in Archived Human Samples
2009
Isomer Distribution of Perfluorocarboxylates in Human Blood: Potential Correlation to Source
2006
Perfluorinated Sulfonamides in Indoor and Outdoor Air and Indoor Dust: Occurrence, Partitioning, and Human Exposure
2005
Prenatal Exposure to Perfluorooctanoate and Risk of Overweight at 20 Years of Age: A Prospective Cohort Study
2012
Polyfluorinated Compounds: Past, Present, and Future
2011 Standout
Automated Solid-Phase Extraction and Measurement of Perfluorinated Organic Acids and Amides in Human Serum and Milk
2004
A Never-Ending Story of Per- and Polyfluoroalkyl Substances (PFASs)?
2017 Standout
Using 2003–2014 U.S. NHANES data to determine the associations between per- and polyfluoroalkyl substances and cholesterol: Trend and implications
2019
Perfluorinated Compounds in the Plasma of Loggerhead and Kemp's Ridley Sea Turtles from the Southeastern Coast of the United States
2005
Determinants of Fetal Exposure to Polyfluoroalkyl Compounds in Baltimore, Maryland
2007
Temporal Shifts in Poly- and Perfluoroalkyl Substances (PFASs) in North Atlantic Pilot Whales Indicate Large Contribution of Atmospheric Precursors
2017
Transfusion-related mortality: the ongoing risks of allogeneic blood transfusion and the available strategies for their prevention
2009 Standout
Novel Diagnostic Algorithm for Identification of Mycobacteria Using Genus-Specific Amplification of the 16S-23S rRNA Gene Spacer and Restriction Endonucleases
2000 Standout
Comprehensive Evaluation of Antibiotics Emission and Fate in the River Basins of China: Source Analysis, Multimedia Modeling, and Linkage to Bacterial Resistance
2015 Standout
PFAS Environmental Pollution and Antioxidant Responses: An Overview of the Impact on Human Field
2020
Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research
2020 Standout
Intensive Care Medicine
2008
Trends in Exposure to Polyfluoroalkyl Chemicals in the U.S. Population: 1999−2008
2011
Immunotoxicity of Perfluorinated Compounds: Recent Developments
2011
Perfluoroalkyl and polyfluoroalkyl substances in the environment: Terminology, classification, and origins
2011 Standout
Trends of polyfluoroalkyl compounds in marine biota and in humans
2010
Polyfluorinated Amides as a Historical PFCA Source by Electrochemical Fluorination of Alkyl Sulfonyl Fluorides
2012
Exploring Indirect Sources of Human Exposure to Perfluoroalkyl Carboxylates (PFCAs): Evaluating Uptake, Elimination, and Biotransformation of Polyfluoroalkyl Phosphate Esters (PAPs) in the Rat
2010
PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps in Understanding
2020
Changes in indoor pollutants since the 1950s
2008
Formaldehyde in the Indoor Environment
2010 Standout
A First Global Production, Emission, And Environmental Inventory For Perfluorooctane Sulfonate
2008
Are humans exposed to increasing amounts of unidentified organofluorine?
2015
Perfluorochemicals in Pooled Serum Samples from United States Residents in 2001 and 2002
2006
Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses
2012 Standout
Pre- and Postnatal Exposure to Perfluorinated Compounds (PFCs)
2010
Effects of air cell injection of perfluorooctane sulfonate before incubation on development of the white leghorn chicken (Gallus domesticus) embryo
2006
Epidemiology of Chagas disease in non endemic countries: the role of international migration
2007
Temporal Trends of PFOS and PFOA in Guillemot Eggs from the Baltic Sea, 1968−2003
2004
Observation of a Commercial Fluorinated Material, the Polyfluoroalkyl Phosphoric Acid Diesters, in Human Sera, Wastewater Treatment Plant Sludge, and Paper Fibers
2009
Associations of in Utero Exposure to Perfluorinated Alkyl Acids with Human Semen Quality and Reproductive Hormones in Adult Men
2013
Determination of Perfluorinated Compounds in the Upper Mississippi River Basin
2010
Exposure of Perfluorinated Chemicals through Lactation: Levels of Matched Human Milk and Serum and a Temporal Trend, 1996–2004, in Sweden
2006
Epidemiology of infection by nontuberculous mycobacteria
1996
The Applicability of Biomonitoring Data for Perfluorooctanesulfonate to the Environmental Public Health Continuum
2006
Association between Serum Perfluorooctanoic Acid (PFOA) and Thyroid Disease in the U.S. National Health and Nutrition Examination Survey
2010
Serum Concentrations of Polyfluoroalkyl Compounds in Faroese Whale Meat Consumers
2008
Polyfluoroalkyl Chemicals in the U.S. Population: Data from the National Health and Nutrition Examination Survey (NHANES) 2003–2004 and Comparisons with NHANES 1999–2000
2007
2015 ESC Guidelines for the management of infective endocarditis
2015 Standout
Using Machine Learning to Classify Bioactivity for 3486 Per- and Polyfluoroalkyl Substances (PFASs) from the OECD List
2019
Applications and societal benefits of plastics
2009 Standout
Subchronic Toxicity of S-111-S-WB in Sprague Dawley Rats
2010
Treatment technologies for aqueous perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA)
2009
Per- and polyfluoroalkyl substances in the environment
2022 StandoutScience
Perfluorooctanesulfonate and Related Fluorochemicals in Human Blood from Several Countries
2004
Sources, Fate and Transport of Perfluorocarboxylates
2005 Standout
Half-Life of Serum Elimination of Perfluorooctanesulfonate,Perfluorohexanesulfonate, and Perfluorooctanoate in Retired Fluorochemical Production Workers
2007 Standout
Stochastic Pharmacokinetic-Pharmacodynamic Modeling for Assessing the Systemic Health Risk of Perfluorooctanoate (PFOA)
2018
Global burden of heart failure: a comprehensive and updated review of epidemiology
2022 Standout
Exposure to Perfluoroalkyl Acids and Markers of Kidney Function among Children and Adolescents Living near a Chemical Plant
2013
Uptake and elimination of perfluorinated phosphonic acids in the rat
2010
Temporal and Spatial Trends in the Occurrence of Human and Veterinary Antibiotics in Aqueous and River Sediment Matrices
2006
Microplastics as an emerging threat to terrestrial ecosystems
2017 Standout
Mycobacterium aviumComplex Infection in the Acquired Immunodeficiency Syndrome
1991 Standout
Application of the Key Characteristics of Carcinogens to Per and Polyfluoroalkyl Substances
2020
The Mycobacterium avium complex
1993
Human health risk of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in edible fish from Huairou Reservoir and Gaobeidian Lake in Beijing, China
2007
Discovery of a Novel Polyfluoroalkyl Benzenesulfonic Acid around Oilfields in Northern China
2017
A Permeability-Limited Physiologically Based Pharmacokinetic (PBPK) Model for Perfluorooctanoic acid (PFOA) in Male Rats
2017
Serum Concentrations of 11 Polyfluoroalkyl Compounds in the U.S. Population: Data from the National Health and Nutrition Examination Survey (NHANES) 1999−2000
2007
Works of R. Herron being referenced
Transfusion‐associated graft‐versus‐host disease in immunocompetent patients: report of a fatal case associated with transfusion of blood from a second‐degree relative, and a survey of predisposing factors
1993
Effective reduction of transfusion‐related acute lung injury risk with male‐predominant plasma strategy in the American Red Cross (2006‐2008)
2010
Trypanosoma cruzi in Los Angeles and Miami blood donors: impact of evolving donor demographics on seroprevalence and implications for transfusion transmission
2002
Transfusion‐related acute lung injury surveillance (2003‐2005) and the potential impact of the selective use of plasma from male donors in the American Red Cross
2007
A blood donor with bacteraemia
2005
Trypanosoma cruzi Parasitemia in US Blood Donors with Serologic Evidence of Infection
2008
Per- and polyfluoroalkyl substances (PFAS) in American Red Cross adult blood donors, 2000–2015
2017
Transmission ofTrypanosoma cruziby Heart Transplantation
2009
DNA probe reactivity of Mycobacterium avium complex isolates from patients without AIDS
1988
Decline in Perfluorooctanesulfonate and Other Polyfluoroalkyl Chemicals in American Red Cross Adult Blood Donors, 2000−2006
2008
Temporal Trends of Perfluoroalkyl Concentrations in American Red Cross Adult Blood Donors, 2000–2010
2012
Analysis of a Homologous Series of Perfluorocarboxylates from American Red Cross Adult Blood Donors, 2000–2001 and 2006
2011
Perfluorooctanesulfonate and other fluorochemicals in the serum of American Red Cross adult blood donors.
2003