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Citing Papers
Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver
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IL-33 Amplifies the Polarization of Alternatively Activated Macrophages That Contribute to Airway Inflammation
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Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis
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Inference and analysis of cell-cell communication using CellChat
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Inflammation and cancer
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Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis
2006
The therapeutic potential of interleukin-6 hyperagonists and antagonists
1997
Expression, regulation, and signaling of the pattern‐recognition receptor nucleotide‐binding oligomerization domain 2 in rheumatoid arthritis synovial fibroblasts
2009
Expression of platelet-derived growth factor in a model of acute liver injury†
1994
Expression and Regulation of Toll-Like Receptor 2 in Rheumatoid Arthritis Synovium
2003
Rheumatoid arthritis
2016 Standout
ENDOTHELIAL CELL RESPONSES TO HYPOXIC STRESS
1999
Cooperation of Ras‐ and c‐Myc–dependent pathways in regulating the growth and invasiveness of synovial fibroblasts in rheumatoid arthritis
2004
Podoplanin: emerging functions in development, the immune system, and cancer
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Expression of angiogenic factors in juvenile rheumatoid arthritis: Correlation with revascularization of human synovium engrafted into SCID mice
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Monocyte chemoattractant protein 1 released from glycosaminoglycans mediates its profibrotic effects in systemic sclerosis via the release of interleukin‐4 from T cells
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Chemokines
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Imaging the Glycosylation State of Cell Surface Glycoproteins by Two‐Photon Fluorescence Lifetime Imaging Microscopy
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Role of platelet-derived growth factors in physiology and medicine
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An Antibody Reactive with Domain 4 of the Platelet-derived Growth Factor β Receptor Allows BB Binding while Inhibiting Proliferation by Impairing Receptor Dimerization
1997
Wound repair and regeneration
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Animal models of inflammatory spinal and sacroiliac joint diseases
2003
TRANCE/RANKL Knockout Mice Are Protected from Bone Erosion in a Serum Transfer Model of Arthritis
2001
Apoptosis and p53 expression in rat adjuvant arthritis
2000
Juvenile idiopathic arthritis
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Direct evidence of high DNA binding activity of transcription factor AP‐1 in rheumatoid arthritis synovium
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The biology and function of fibroblasts in cancer
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Enthesitis and ankylosis in spondyloarthropathy: What is the target of the immune response?
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Decoy receptor 3 expressed in rheumatoid synovial fibroblasts protects the cells against fas‐induced apoptosis
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Studies on the contribution of c-fos/AP-1 to arthritic joint destruction.
1997
Synovial fibroblasts spread rheumatoid arthritis to unaffected joints
2009
Cysteine cathepsins and extracellular matrix degradation
2014
Principles of bioactive lipid signalling: lessons from sphingolipids
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Systemic sclerosis
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Psoriasis
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The Pathogenesis of Rheumatoid Arthritis
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Synovial Fibroblast-Like Cells Strongly Express Jun-B and C-Fos Proto-Oncogenes in Rheumatoid- and Osteoarthritis
1995
Scleroderma
2009 Standout
Stat6 and Jak1 Are Common Elements in Platelet-derived Growth Factor and Interleukin-4 Signal Transduction Pathways in NIH 3T3 Fibroblasts
1996
The SCID mouse model: novel therapeutic targets ? lessons from gene transfer
2003
H‐ras oncogene point mutations in arthritic synovium
1997
Expression of osteoclast differentiation factor in rheumatoid arthritis
2000
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Regulation of PDGF and its receptors in fibrotic diseases
2004
Angiogenesis and chemokines in rheumatoid arthritis and other systemic inflammatory rheumatic diseases
2002
Evolving concepts of rheumatoid arthritis
2003 StandoutNature
The KRN mouse model of inflammatory arthritis
2003
The Early-Immediate Gene EGR-1 Is Induced by Transforming Growth Factor-β and Mediates Stimulation of Collagen Gene Expression
2006
Regulation of Joint Destruction and Inflammation by p53 in Collagen-Induced Arthritis
2002
The pathogenesis of psoriatic arthritis
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Ankylosing spondylitis
2007 Standout
Invasiveness of synovial fibroblasts is regulated by p53 in the SCID mouse in vivo model of cartilage invasion
2001
Evidence that cytokines play a role in rheumatoid arthritis
2008
Dominant-negative p53 mutations in rheumatoid arthritis
1999
Involvement of receptor activator of NFκB ligand and tumor necrosis factor-α in bone destruction in rheumatoid arthritis
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Remodelling the extracellular matrix in development and disease
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Induction of cartilage damage by overexpression of T cell interleukin‐17A in experimental arthritis in mice deficient in interleukin‐1
2005
Inflammatory Markers and Exercise: Differences Related to Exercise Type
2003
Treatment of active ankylosing spondylitis with infliximab: a randomised controlled multicentre trial
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Systemic sclerosis: a prototypic multisystem fibrotic disorder
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Tissue localization of beta receptors for platelet-derived growth factor and platelet-derived growth factor B chain during wound repair in humans.
1993
Autoimmune disease. a problem of defective apoptosis
1994
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Decreased susceptibility to Fas-induced apoptosis of systemic sclerosis dermal fibroblasts
2001
Endothelin, an endothelial‐dependent vasoconstrictor in scleroderma. Enhanced production and profibrotic action
1991
Alternative Activation of Macrophages: Mechanism and Functions
2010 Standout
Cell death in rheumatoid arthritis
2009
Rheumatoid arthritis
2010 Standout
Regulation of Connective Tissue Synthesis in Systemic Sclerosis
1995
Recombinant Human Single Chain Fv Antibodies Recognizing Human Interleukin-6
1998 StandoutNobel
Expression of Endothelin-1 in the Lungs of Patients with Pulmonary Hypertension
1993 Standout
The role of mesenchymal cells in the pathophysiology of inflammatory arthritis
2006
Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor
2000
Experimentally-Derived Fibroblast Gene Signatures Identify Molecular Pathways Associated with Distinct Subsets of Systemic Sclerosis Patients in Three Independent Cohorts
2015
NF-κB: a key role in inflammatory diseases
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Apoptosis and functional fas antigen in rheumatoid arthritis synoviocytes
1995
Protective and pathogenic functions of macrophage subsets
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Sex differences in immune responses
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Type I, II, III, IV, V, and VI Collagens Serve as Extracellular Ligands for the Isoforms of Platelet-derived Growth Factor (AA, BB, and AB)
1996
Nintedanib inhibits macrophage activation and ameliorates vascular and fibrotic manifestations in the Fra2 mouse model of systemic sclerosis
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Sex Differences in Autoimmune Disease from a Pathological Perspective
2008
Sustained Activation of Fibroblast Transforming Growth Factor-β/Smad Signaling in a Murine Model of Scleroderma
2003
Arthritis and pneumonitis produced by the same T cell clones from mice with spontaneous autoimmune arthritis
2008 StandoutNobel
Obstructive sleep apnoea and its cardiovascular consequences
2008 Standout
Expression of sentrin, a novel antiapoptotic molecule, at sites of synovial invasion in rheumatoid arthritis
2000
Chronic thromboembolic pulmonary hypertension
2014
PATHOGENESIS OF RHEUMATOID ARTHRITIS: THE ROLE OF SYNOVIOCYTES
2001
Garden of therapeutic delights: new targets in rheumatic diseases
2009
Roles of activin in tissue repair, fibrosis, and inflammatory disease
2006
Invasive fibroblast‐like synoviocytes in rheumatoid arthritis. Passive responders or transformed aggressors?
1996
RADIOLOGIC DIAGNOSIS AND PATHOLOGY OF THE SPONDYLOARTHROPATHIES
1998
Regulation of apoptosis in fibroblast‐like synoviocytes by the hypoxia‐induced Bcl‐2 family member Bcl‐2/adenovirus E1B 19‐kd protein–interacting protein 3
2007
Fibroblast‐like synoviocytes: key effector cells in rheumatoid arthritis
2009 Standout
Osteoclasts are essential for TNF-α–mediated joint destruction
2002
Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice.
1996
CXCR4 and CCR5 on Human Thymocytes: Biological Function and Role in HIV-1 Infection
1998
Nintedanib for Systemic Sclerosis–Associated Interstitial Lung Disease
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α9 Integrin and Its Ligands Constitute Critical Joint Microenvironments for Development of Autoimmune Arthritis
2009
Joint NOD2/RIPK2 Signaling Regulates IL-17 Axis and Contributes to the Development of Experimental Arthritis
2012
Selective upregulation of platelet-derived growth factor alpha receptors by transforming growth factor beta in scleroderma fibroblasts.
1992
Apoptosis in the Pathogenesis and Treatment of Disease
1995 StandoutScience
IL-17 and Th17 Cells
2009 Standout
Early joint erosions and serum levels of matrix metalloproteinase 1, matrix metalloproteinase 3, and tissue inhibitor of metalloproteinases 1 in rheumatoid arthritis
2001
Targeting RGD Recognizing Integrins: Drug Development, Biomaterial Research, Tumor Imaging and Targeting
2006
Endothelial Nitric Oxide Synthase Activation by Tumor Necrosis Factor α Through Neutral Sphingomyelinase 2, Sphingosine Kinase 1, and Sphingosine 1 Phosphate Receptors
2005
AP-1 and NF-kB Regulation in Rheumatoid Arthritis and Murine Collagen-Induced Arthritis
1998
Management of Massive and Submassive Pulmonary Embolism, Iliofemoral Deep Vein Thrombosis, and Chronic Thromboembolic Pulmonary Hypertension
2011 Standout
Uncontrolled Expression of Vascular Endothelial Growth Factor and Its Receptors Leads to Insufficient Skin Angiogenesis in Patients With Systemic Sclerosis
2004
Regional analysis ofp53mutations in rheumatoid arthritis synovium
2002
CSF-1–Dependent Red Pulp Macrophages Regulate CD4 T Cell Responses
2011 StandoutNobel
Chronic Thromboembolic Pulmonary Hypertension
2006 Standout
Thymocyte-Thymic Epithelial Cell Interaction Leads to High-Level Replication of Human Immunodeficiency Virus Exclusively in Mature CD4+CD8−CD3+Thymocytes: a Critical Role for Tumor Necrosis Factor and Interleukin-7
1999 StandoutNobel
Bcl-2 Expression in Synovial Fibroblasts Is Essential for Maintaining Mitochondrial Homeostasis and Cell Viability
2000
Nintedanib in Progressive Fibrosing Interstitial Lung Diseases
2019 Standout
Gene transfer of cytokine inhibitors into human synovial fibroblasts in the SCID mouse model
1999
Graded Attenuation of TCR Signaling Elicits Distinct Autoimmune Diseases by Altering Thymic T Cell Selection and Regulatory T Cell Function
2010 StandoutNobel
Mcl-1 Is Essential for the Survival of Synovial Fibroblasts in Rheumatoid Arthritis
2005
Chemokine Receptor CX3CR1 Mediates Skin Wound Healing by Promoting Macrophage and Fibroblast Accumulation and Function
2008
Positive Regulation of CXCR4 Expression and Signaling by Interleukin-7 in CD4+Mature Thymocytes Correlates with Their Capacity To Favor Human Immunodeficiency X4 Virus Replication
2003 StandoutNobel
Platelet-derived growth factor is an autocrine growth stimulator in retinal pigmented epithelial cells
1994
Regulation of synoviocyte proliferation, apoptosis, and invasion by the p53 tumor suppressor gene.
1998
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Nod2 Deficiency Augments Th17 Responses and Exacerbates Autoimmune Arthritis
2018 StandoutNobel
Inhibition of platelet-derived growth factor autocrine growth stimulation by a monoclonal antibody to the human alpha platelet-derived growth factor receptor.
1993
Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium
1997
Regulation of Wound Healing by Growth Factors and Cytokines
2003 Standout
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor
1999 Standout
Expression of platelet-derived growth factor and its receptors in normal human liver and during active hepatic fibrogenesis.
1996
Works of R E Gay being referenced
Alternatively spliced CS-1 fibronectin isoform and its receptor VLA-4 in rheumatoid arthritis synovium.
1997
Cysteine proteinase cathepsin K mRNA is expressed in synovium of patients with rheumatoid arthritis and is detected at sites of synovial bone destruction.
1998
Ultrastructural demonstration of apoptosis, Fas and Bcl-2 expression of rheumatoid synovial fibroblasts.
1996
The TNF superfamily member LIGHT contributes to survival and activation of synovial fibroblasts in rheumatoid arthritis
2007
VIRUS-LIKE PARTICLES IN SYNOVIAL FLUIDS FROM PATIENTS WITH RHEUMATOID ARTHRITIS
1993
The dual inhibitor of lipoxygenase and cyclooxygenase ML3000 decreases the expression of CXCR3 ligands
2007
Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of a cell surface-targeted plasmin inhibitor
2000
Synovial fibroblasts: key players in rheumatoid arthritis
2006
Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3
2003
Cellular basis and oncogene expression of rheumatoid joint destruction
1989
Die Rheumatoide Arthritis: Neuentwicklungen in der Pathogenese unter besonderer Berücksichtigung der synovialen Fibroblasten
2001
Increased serum levels of non-collagenous matrix proteins (cartilage oligomeric matrix protein and melanoma inhibitory activity) in marathon runners
2000
Immunohistologic Demonstration of Platelet-derived Growth Factor (PDGF) and sis-Oncogene Expression in Scleroderma
1989
Abundant expression of the interleukin (IL)23 subunit p19, but low levels of bioactive IL23 in the rheumatoid synovium: differential expression and Toll-like receptor-(TLR) dependent regulation of the IL23 subunits, p19 and p40, in rheumatoid arthritis
2008
Molecular and cellular mechanisms of joint destruction in rheumatoid arthritis: two cellular mechanisms explain joint destruction?
1993
Collagenase, cathepsin B and cathepsin L gene expression in the synovial membrane of patients with early inflammatory arthritis
1999
Spontaneous expression of immediately-early response genes c-fos and egr-1 in collagenase-producing rheumatoid synovial fibroblasts
1992
S100A4 is expressed at site of invasion in rheumatoid arthritis synovium and modulates production of matrix metalloproteinases
2006
Inhibition of cartilage destruction by double gene transfer of IL-1Ra and IL-10 involves the activin pathway
2002
Overexpression of zinc-finger transcription factor Z-225/Egr-1 in synoviocytes from rheumatoid arthritis patients.
1994
Prolactin and prolactin-like polypeptides in rheumatoid arthritis
1999
Membrane-type-1 matrix metalloproteinase is abundantly expressed in fibroblasts and osteoclasts at the bone-implant interface of aseptically loosened joint arthroplasties in situ.
1999
Angiogenic and angiostatic factors in the molecular control of angiogenesis.
2003
[Fusion of vertebrae and the sacroiliac joint by cartilaginous tissue in HLA-B27 transgenic rats].
1996
Effects of TIMP-1 and TIMP-3 gene transfer on invasiveness, proliferation and apoptosis of rheumatoid arthritis (RA) synovial fibroblasts (RA-SF)
2002
A new double labeling technique for combined in situ hybridization and immunohistochemical analysis.
1994
Human IL-1Ra gene transfer into human synovial fibroblasts is chondroprotective.
1997
Immunohistological studies of bone marrow collagen.
1984