Citation Impact
Citing Papers
Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways
2011
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
2015 StandoutNobel
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
Rationally engineered Cas9 nucleases with improved specificity
2015 StandoutScience
PKA phosphorylation couples hepatic inositol-requiring enzyme 1α to glucagon signaling in glucose metabolism
2011
The iCRISPR Platform for Rapid Genome Editing in Human Pluripotent Stem Cells
2014
RACK1, A multifaceted scaffolding protein: Structure and function
2011
Both TALENs and CRISPR/Cas9 directly target the HBB IVS2–654 (C > T) mutation in β-thalassemia-derived iPSCs
2015
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
Systematic quantification of HDR and NHEJ reveals effects of locus, nuclease, and cell type on genome-editing
2016
Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells
2014
RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors
2018
CRISPR/Cas9-mediated targeted chromosome elimination
2017
Precision cancer mouse models through genome editing with CRISPR-Cas9
2015
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Precise Correction of the Dystrophin Gene in Duchenne Muscular Dystrophy Patient Induced Pluripotent Stem Cells by TALEN and CRISPR-Cas9
2014 Nobel
BAX inhibitor‐1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response
2011
The Unfolded Protein Response and Cell Fate Control
2017
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
Mechanisms, regulation and functions of the unfolded protein response
2020 Standout
Repurposing endogenous type I CRISPR-Cas systems for programmable gene repression
2014
Systematic analysis of CRISPR–Cas9 mismatch tolerance reveals low levels of off-target activity
2015
Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference
2015
Direct Association of Unfolded Proteins with Mammalian ER Stress Sensor, IRE1β
2012
High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
2016 StandoutNature
Adenine base editing in an adult mouse model of tyrosinaemia
2019
Meganuclease targeting of PCSK9 in macaque liver leads to stable reduction in serum cholesterol
2018
Efficient and Allele-Specific Genome Editing of Disease Loci in Human iPSCs
2014
The gut microbiota and its relationship to diet and obesity
2012
Human Genetics Shape the Gut Microbiome
2014 Standout
Expanding the Biologist’s Toolkit with CRISPR-Cas9
2015 StandoutNobel
Death by TNF: a road to inflammation
2022
Development of an intein-mediated split–Cas9 system for gene therapy
2015
Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes
2017
Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells
2015
CRISPR/Cas-Mediated Base Editing: Technical Considerations and Practical Applications
2019
Hallmarks of aging: An expanding universe
2023 Standout
Programmable RNA Tracking in Live Cells with CRISPR/Cas9
2016 StandoutNobel
Engineering Human Stem Cell Lines with Inducible Gene Knockout using CRISPR/Cas9
2015
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
2012 Standout
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
Interaction between high-density lipoproteins and inflammation: Function matters more than concentration!
2020
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
The changing landscape of atherosclerosis
2021 StandoutNature
Modulating stress responses by the UPRosome: A matter of life and death
2011
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
Off-target Effects in CRISPR/Cas9-mediated Genome Engineering
2015 Standout
Defining and improving the genome-wide specificities of CRISPR–Cas9 nucleases
2016
CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes
2015
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
2017 StandoutNatureNobel
Therapeutic genome editing: prospects and challenges
2015
Nonmuscle Myosin IIB Links Cytoskeleton to IRE1α Signaling during ER Stress
2012
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
2016 Standout
Dynamical features of thePlasmodium falciparumribosome during translation
2015 StandoutNobel
Endoplasmic reticulum stress-sensing mechanisms in yeast and mammalian cells
2010
In vivo targeted single-nucleotide editing in zebrafish
2018
Genome Engineering Using Adeno-associated Virus: Basic and Clinical Research Applications
2015
A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture
2015
Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate
2018
Lipid-Modifying Agents, From Statins to PCSK9 Inhibitors
2020
In vivo genome editing using Staphylococcus aureus Cas9
2015 StandoutNature
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
High-throughput functional genomics using CRISPR–Cas9
2015
Conformational control of DNA target cleavage by CRISPR–Cas9
2015 StandoutNatureNobel
Protein Disulfide Isomerase A6 Controls the Decay of IRE1α Signaling via Disulfide-Dependent Association
2014
Adeno-associated virus vector as a platform for gene therapy delivery
2019 Standout
CRISPR/Cas9‐mediated genome engineering: An adeno‐associated viral (AAV) vector toolbox
2014
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
BH3‐only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α
2012
The next generation of CRISPR–Cas technologies and applications
2019
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
2014 Standout
In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9
2014
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
The unfolded protein response transducer IRE1α prevents ER stress‐induced hepatic steatosis
2011
Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes
2017
Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation
2020 StandoutNobel
Efficient Ablation of Genes in Human Hematopoietic Stem and Effector Cells using CRISPR/Cas9
2014
CRISPR-Cas9 genome editing induces megabase-scale chromosomal truncations
2019
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Functional Correction of Large Factor VIII Gene Chromosomal Inversions in Hemophilia A Patient-Derived iPSCs Using CRISPR-Cas9
2015
A 20-year retrospective review of global aquaculture
2021 StandoutNature
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Efficient gene editing in adult mouse livers via adenoviral delivery of CRISPR/Cas9
2014
Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death
2017
Human Germline Genome Editing
2017
Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications
2017 StandoutNobel
Perspective: Embryo editing needs scrutiny
2015 StandoutNatureNobel
Proteostasis control by the unfolded protein response
2015
In utero CRISPR-mediated therapeutic editing of metabolic genes
2018
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Efficient delivery of nuclease proteins for genome editing in human stem cells and primary cells
2015
Genome-editing Technologies for Gene and Cell Therapy
2016
Genome-editing revolution: My whirlwind year with CRISPR
2015 StandoutNatureNobel
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
Delivery and Specificity of CRISPR/Cas9 Genome Editing Technologies for Human Gene Therapy
2015
The Daunting Economics of Therapeutic Genome Editing
2019
Development and Application of Base Editors
2019
Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses
2015
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity
2022 StandoutNobel
A prudent path forward for genomic engineering and germline gene modification
2015 StandoutScienceNobel
The Unfolded Protein Response: Integrating Stress Signals Through the Stress Sensor IRE1α
2011
Inhibition of HIV-1 infection of primary CD4+ T-cells by gene editing of CCR5 using adenovirus-delivered CRISPR/Cas9
2015
From Genomics to Gene Therapy: Induced Pluripotent Stem Cells Meet Genome Editing
2015 Nobel
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering
2010
Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
2016 StandoutScience
The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
2011 StandoutScience
Disease reduction in aquaculture with genetic and genomic technology: current and future approaches
2017
Delivery technologies for genome editing
2017
Lipids and Lipid Derivatives for RNA Delivery
2021
Evaluating and Enhancing Target Specificity of Gene-Editing Nucleases and Deaminases
2019
Genome Editing in Cardiovascular Biology
2017
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
Target specificity of the CRISPR‐Cas9 system
2014
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
ASXL1 mutation correction by CRISPR/Cas9 restores gene function in leukemia cells and increases survival in mouse xenografts
2015
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
In Vivo Base Editing of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) as a Therapeutic Alternative to Genome Editing
2017
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of Qiurong Ding being referenced
Cas9-nickase–mediated genome editing corrects hereditary tyrosinemia in rats
2018
Genetic Modulation of RNA Splicing with a CRISPR-Guided Cytidine Deaminase
2018
Apolipoprotein A-I stimulates AMP-activated protein kinase and improves glucose metabolism
2007
Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis
2019
Low Incidence of Off-Target Mutations in Individual CRISPR-Cas9 and TALEN Targeted Human Stem Cell Clones Detected by Whole-Genome Sequencing
2014
A Crucial Role for RACK1 in the Regulation of Glucose-Stimulated IRE1α Activation in Pancreatic β Cells
2010
Permanent Alteration of PCSK9 With In Vivo CRISPR-Cas9 Genome Editing
2014
CRISPR-Cas9 Targeting of PCSK9 in Human Hepatocytes In Vivo—Brief Report
2016