Citation Impact
Citing Papers
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
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2001
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1995
Caught up in a Wnt storm: Wnt signaling in cancer
2003
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2002
F-Spondin, Expressed in Somite Regions Avoided by Neural Crest Cells, Mediates Inhibition of Distinct Somite Domains to Neural Crest Migration
1999
Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands
1996 Nature
The crystal structure of an Eph receptor SAM domain reveals a mechanism for modular dimerization.
1999
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1995
Molecular basis of semaphorin-mediated axon guidance
2000
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1997
Multiple Ephrins Control Cell Organization in C. elegans Using Kinase-Dependent and -Independent Functions of the VAB-1 Eph Receptor
1999
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1997
An ephrin-A-dependent Signaling Pathway Controls Integrin Function and Is Linked to the Tyrosine Phosphorylation of a 120-kDa Protein
2001
Oncogenic kinase signalling
2001 StandoutNature
Compartments and their boundaries in vertebrate brain development
2005
Eomesodermin, a Key Early Gene in Xenopus Mesoderm Differentiation
1996 StandoutNobel
Structural Basis for Autoinhibition of the EphB2 Receptor Tyrosine Kinase by the Unphosphorylated Juxtamembrane Region
2001
Genetic Ablation and Restoration of the Olfactory Topographic Map
2000 StandoutNobel
Excitatory Eph receptors and adhesive ephrin ligands
2001
The Ephrin VAB-2/EFN-1 Functions in Neuronal Signaling to Regulate Epidermal Morphogenesis in C. elegans
1999
The Receptor Tyrosine Kinase EphB2 Regulates NMDA-Dependent Synaptic Function
2001
Requirement for Notch1 signals at sequential early stages of intrathymic T cell development
2005
Temporal and Spatial Effects of Sonic Hedgehog Signaling in Chick Eye Morphogenesis
2001
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2001
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2000
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
1996 StandoutNature
Cell Signalling: Receptor orphans find a family
1995
Pax2 contributes to inner ear patterning and optic nerve trajectory
1996
Induction of a specific muscle cell type by a hedgehog-like protein in zebrafish
1996 Nature
The Interpretation of Position in a Morphogen Gradient as Revealed by Occupancy of Activin Receptors
1998 StandoutNobel
The G Protein-coupled Receptor CL1 Interacts Directly with Proteins of the Shank Family
2000 StandoutNobel
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1997
Neural development: Bidirectional signals establish boundaries
1999
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2010
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2002
Structural and functional features of central nervous system lymphatic vessels
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Eph Receptors and Ligands Comprise Two Major Specificity Subclasses and Are Reciprocally Compartmentalized during Embryogenesis
1996
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2010 Nature
Odorant Receptors Govern the Formation of a Precise Topographic Map
1998 StandoutNobel
Notch signalling: a simple pathway becomes complex
2006 Standout
Functional activation of EphA5 receptor does not promote cell proliferation in the aberrant EphA5 expressing human glioblastoma U-118 MG cell line
1999
Stages of embryonic development of the zebrafish
1995 Standout
Invasiveness of breast carcinoma cells and transcript profile: Eph receptors and ephrin ligands as molecular markers of potential diagnostic and prognostic application
2004
The N-terminal globular domain of Eph receptors is sufficient for ligand binding and receptor signaling
1997
Regulation of repulsion versus adhesion by different splice forms of an Eph receptor
2000 Nature
A Homeodomain Protein Code Specifies Progenitor Cell Identity and Neuronal Fate in the Ventral Neural Tube
2000
Patterning of the Caenorhabditis elegans head region by the Pax-6 family member vab-3
1995 StandoutNatureNobel
Mechanisms and functions of eph and ephrin signalling
2002 Standout
A gene expression atlas of the central nervous system based on bacterial artificial chromosomes
2003 StandoutNature
Regulation of vertebrate neural cell fate by transcription factors
1996
Eph receptors and ephrins in neural development
1999
Eph receptors and ephrins: Regulators of guidance and assembly
2000
The EphA4 and EphB1 receptor tyrosine kinases and ephrin-B2 ligand regulate targeted migration of branchial neural crest cells
1997
Collective cell migration in morphogenesis, regeneration and cancer
2009 Standout
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2001
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2001 Standout
Crystal structure of the ligand-binding domain of the receptor tyrosine kinase EphB2
1998 Nature
Topographically Specific Effects of ELF-1 on Retinal Axon Guidance In Vitro and Retinal Axon Mapping In Vivo
1996
Vascular-specific growth factors and blood vessel formation
2000 StandoutNature
Neuroligins and neurexins link synaptic function to cognitive disease
2008 StandoutNatureNobel
Lens development and crystallin gene expression: many roles for Pax‐6
1996
Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis
1999
The protein tyrosine kinase family of the human genome
2000
Cu-free click cycloaddition reactions in chemical biology
2010 StandoutNobel
Drosophila Clock Can Generate Ectopic Circadian Clocks
2003 StandoutNobel
Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, Angiopoietins, and ephrins in vascular development
1999
Notch signalling in vertebrate neural development
2006
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
2003 StandoutNature
Nuk Controls Pathfinding of Commissural Axons in the Mammalian Central Nervous System
1996
Patterning activities of vertebrate hedgehog proteins in the developing eye and brain
1995
Semaphorin-mediated axonal guidance via Rho-related G proteins
2001
Crystal Structure of an Ephrin Ectodomain
2001
Pax proteins and eye development
1996
Function for Hedgehog Genes in Zebrafish Retinal Development
2000
Multiple roles of eph receptors and ephrins in neural development
2001
Symmetrical Mutant Phenotypes of the Receptor EphB4 and Its Specific Transmembrane Ligand ephrin-B2 in Cardiovascular Development
1999
Are Complex Behaviors Specified by Dedicated Regulatory Genes? Reasoning from Drosophila
2001 StandoutNobel
Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation
1999
Mutations in the human Sonic Hedgehog gene cause holoprosencephaly
1996 Standout
Wnt signalling in stem cells and cancer
2005 StandoutNature
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
2010 StandoutNature
Regulation of Left–Right Asymmetries in the Zebrafish by Shh and BMP4
1999
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases
1994
Pax6 Controls Progenitor Cell Identity and Neuronal Fate in Response to Graded Shh Signaling
1997
The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization
2000
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
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Kinase-Dependent and Kinase-Independent Functions of EphA4 Receptors in Major Axon Tract Formation In Vivo
2001
Distinctcis-Essential Modules Direct the Time–Space Pattern of thePax6Gene Activity
1999 StandoutNobel
Ephrin-A5 (AL-1/RAGS) Is Essential for Proper Retinal Axon Guidance and Topographic Mapping in the Mammalian Visual System
1998
Angiogenesis as a therapeutic target
2005 StandoutNature
The Cytoplasmic Domain of the Ligand EphrinB2 Is Required for Vascular Morphogenesis but Not Cranial Neural Crest Migration
2001
Transcriptional Regulation of the Human PAX6 Gene Promoter
1997
Eph Family Transmembrane Ligands Can Mediate Repulsive Guidance of Trunk Neural Crest Migration and Motor Axon Outgrowth
1997
In Vivo Tyrosine Phosphorylation Sites of Activated Ephrin-B1 and EphB2 from Neural Tissue
2001
Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4
1998 Standout
Topographic Mapping in Dorsoventral Axis of the Xenopus Retinotectal System Depends on Signaling through Ephrin-B Ligands
2002
Pax-6 functions in boundary formation and axon guidance in the embryonic mouse forebrain
1997
In Vivo Imaging of Membrane-Associated Glycans in Developing Zebrafish
2008 StandoutScienceNobel
Comparative synteny cloning of zebrafish you-too: mutations in the Hedgehog target gli2 affect ventral forebrain patterning
1999
Axonal Ephrin-As and Odorant Receptors
2003 StandoutNobel
GROWTH CONE GUIDANCE: First Steps Towards a Deeper Understanding
1999
CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling
2009
Collective cell migration in development
2009
Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo.
1996
Regulation of retinal ganglion cell production by Sonic hedgehog
2001
Tyrosine Phosphorylation of Transmembrane Ligands for Eph Receptors
1997 StandoutScience
Patterning the Vertebrate Neuraxis
1996 Science
Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation.
1996
Loss ofEph-receptorexpression correlates with loss of cell adhesion and chondrogenic capacity inHoxa13mutant limbs
2001 StandoutNobel
β-arrestin- but not G protein-mediated signaling by the “decoy” receptor CXCR7
2009 StandoutNobel
A role for the EphA family in the topographic targeting of vomeronasal axons
2001
CXCL12 (SDF1α)-CXCR4/CXCR7 Pathway Inhibition: An Emerging Sensitizer for Anticancer Therapies?
2011
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
Oligomeric Structure of the Human EphB2 Receptor SAM Domain
1999 Science
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage
2004 StandoutNobel
Conserved regulation of the lymphocyte-specific expression oflckin the Fugu and mammals
2002 StandoutNobel
Fibroblast Growth Factor Receptor-Mediated Rescue of x-Ephrin B1-Induced Cell Dissociation in XenopusEmbryos
2000
Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina
2000
The Taxonomy of Developmental Control in Caenorhabditis elegans
1998 StandoutScienceNobel
Neural Science
2000 StandoutNobel
Nodal signaling patterns the organizer
2000
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
Retinal axon growth cones respond to EphB extracellular domains as inhibitory axon guidance cues
2001
Regionalization within the mammalian telencephalon is mediated by changes in responsiveness to Sonic Hedgehog
1998
Imaging the glycome
2008 StandoutNobel
Eph Receptors and Ephrin Ligands: Important Players in Angiogenesis and Tumor Angiogenesis
2010
Force Generation, Transmission, and Integration during Cell and Tissue Morphogenesis
2011
EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract
1998
The Molecular Biology of Axon Guidance
1996 StandoutScience
Cell-type specific and estrogen dependent expression of the receptor tyrosine kinase EphB4 and its ligand ephrin-B2 during mammary gland morphogenesis
1998
Phosphorylation of Tyrosine Residues in the Kinase Domain and Juxtamembrane Region Regulates the Biological and Catalytic Activities of Eph Receptors
2000
THE EPHRINS AND EPH RECEPTORS IN NEURAL DEVELOPMENT
1998
Forebrain patterning defects in Small eye mutant mice
1996
The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals
2001 Nature
A Transient Population of Neurons Pioneers the Olfactory Pathway in the Zebrafish
1998
The VAB-1 Eph Receptor Tyrosine Kinase Functions in Neural and Epithelial Morphogenesis in C. elegans
1998
Morphogen gradient interpretation
2001 StandoutNatureNobel
SynCAM, a Synaptic Adhesion Molecule That Drives Synapse Assembly
2002 StandoutScienceNobel
Works of Qiling Xu being referenced
Control of cell behaviour by signalling through Eph receptors and ephrins
2000
Eph-related receptors and their ligands: mediators of contact dependent cell interactions
1997
Eph receptors and ephrins restrict cell intermingling and communication
1999 Nature
In vivo cell sorting in complementary segmental domains mediated by Eph receptors and ephrins
1999 Nature
Characterisation of five novel zebrafish Eph-related receptor tyrosine kinases suggests roles in patterning the neural plate
1997
Function of the Eph-related kinase rtk1 in patterning of the zebrafish forebrain
1996 Nature
Regulatory gene expression boundaries demarcate sites of neuronal differentiation in the embryonic zebrafish forebrain
1994
Control of Chemokine-Guided Cell Migration by Ligand Sequestration
2008
Notch Activation Regulates the Segregation and Differentiation of Rhombomere Boundary Cells in the Zebrafish Hindbrain
2004
Midline signalling is required for Pax gene regulation and patterning of the eyes
1995
Expression of truncated Sek-1 receptor tyrosine kinase disrupts the segmental restriction of gene expression in the Xenopus and zebrafish hindbrain
1995
Spatially regulated expression of three receptor tyrosine kinase genes during gastrulation in the zebrafish
1994