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Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer 2009 2026 2014 2020 1.4k
  1. Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer (2009)
    Suzanne Ostrand‐Rosenberg, Pratima Sinha The Journal of Immunology

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The fission yeast cdc19+ gene encodes a member of the MCM family of replication proteins
1994 StandoutNobel
Identification, purification, and cloning of a polypeptide (PRTF/GRM) that binds to mating-specific promoter elements in yeast.
1990
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2010
Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell–suppressive activity
2008
Myeloid‐derived suppressor cell heterogeneity in human cancers
2014
A protein involved in minichromosome maintenance in yeast binds a transcriptional enhancer conserved in eukaryotes.
1989
Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast.
1993
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1999
S Phase of the Cell Cycle
1989 Science
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1992
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2009
Mcm2 and Mcm3, two proteins important for ARS activity, are related in structure and function.
1991
Myeloid-Derived Suppressor Cells in the Development of Lung Cancer
2013
Intratumoral Injection of CpG Oligonucleotides Induces the Differentiation and Reduces the Immunosuppressive Activity of Myeloid-Derived Suppressor Cells
2012
Immunosuppressive Strategies that are Mediated by Tumor Cells
2006
Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host
2007
Yeast chromosome replication and segregation
1988
The ORC1 homolog orp1 in fission yeast plays a key role in regulating onset of S phase.
1996 StandoutNobel
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2016 StandoutNobel
A group of interacting yeast DNA replication genes.
1991
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2008
Breast cancer instructs dendritic cells to prime interleukin 13–secreting CD4+ T cells that facilitate tumor development
2007
Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast
1997
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2010 StandoutNobel
The phenotype of the minichromosome maintenance mutant mcm3 is characteristic of mutants defective in DNA replication.
1990
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2013
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2014 Standout
Myeloid-Derived Suppressor Cells as a Potential Therapy for Experimental Autoimmune Myasthenia Gravis
2014
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2006
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Subpopulations of myeloid‐derived suppressor cells impair T cell responses through independent nitric oxide‐related pathways
2013
Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing mice
2011
INITIATION OF DNA REPLICATION IN EUKARYOTIC CELLS
1997
THE UBIQUITIN SYSTEM
1998 StandoutNobel
DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period.
1994
Fission yeast cdc21, a member of the MCM protein family, is required for onset of S phase and is located in the nucleus throughout the cell cycle.
1996

Works of Pratima Sinha being referenced

HMGB1 Enhances Immune Suppression by Facilitating the Differentiation and Suppressive Activity of Myeloid-Derived Suppressor Cells
2014
Myeloid-Derived Suppressor Cells Inhibit T-Cell Activation by Depleting Cystine and Cysteine
2009
Myeloid-Derived Suppressor Cells Down-Regulate L-Selectin Expression on CD4+ and CD8+ T Cells
2009
Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer
2009 Standout
Regulating the suppressors: apoptosis and inflammation govern the survival of tumor-induced myeloid-derived suppressor cells (MDSC)
2012
Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression
2012
Induction of Cell Proliferation and Apoptosis: Dependence on the Dose of the Inducer
1999
Proteomic Pathway Analysis Reveals Inflammation Increases Myeloid-Derived Suppressor Cell Resistance to Apoptosis
2010
Signal transducer and activator of transcription 6 (Stat6) and CD1: inhibitors of immunosurveillance against primary tumors and metastatic disease
2004
The mcm2-1 mutation of yeast causes DNA damage with a RAD9 requirement for repair
1995
MCM21 and MCM22, two novel genes of the yeast Saccharomyces cerevisiae are required for chromosome transmission
1999
The mcm2 mutation of yeast affects replication, rather than segregation or amplification of the two micron plasmid
1992
RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis
2008
Tumor immunity: a balancing act between T cell activation, macrophage activation and tumor-induced immune suppression
2005
Proinflammatory S100 Proteins Regulate the Accumulation of Myeloid-Derived Suppressor Cells
2008
Reduction of Myeloid-Derived Suppressor Cells and Induction of M1 Macrophages Facilitate the Rejection of Established Metastatic Disease
2005
Cross-talk among myeloid-derived suppressor cells, macrophages, and tumor cells impacts the inflammatory milieu of solid tumors
2014
Reduced Inflammation in the Tumor Microenvironment Delays the Accumulation of Myeloid-Derived Suppressor Cells and Limits Tumor Progression
2007
Interleukin-13–regulated M2 Macrophages in Combination with Myeloid Suppressor Cells Block Immune Surveillance against Metastasis
2005
MUTANTS OF S. CEREVISIAE DEFECTIVE IN THE MAINTENANCE OF MINICHROMOSOMES
1984
Inflammation Induces Myeloid-Derived Suppressor Cells that Facilitate Tumor Progression
2006
Cross-Talk between Myeloid-Derived Suppressor Cells and Macrophages Subverts Tumor Immunity toward a Type 2 Response
2007
Myeloid-derived suppressor cells express the death receptor Fas and apoptose in response to T cell–expressed FasL
2011
Surgical Removal of Primary Tumor Reverses Tumor-Induced Immunosuppression Despite the Presence of Metastatic Disease
2004
A mutant that affects the function of autonomously replicating sequences in yeast
1986
Tumor‐induced myeloid‐derived suppressor cell function is independent of IFN‐γ and IL‐4Rα
2012
A nonclassical non-Vα14Jα18 CD1d-restricted (type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance
2005
Prostaglandin E2 Promotes Tumor Progression by Inducing Myeloid-Derived Suppressor Cells
2007
Inflammation enhances myeloid-derived suppressor cell cross-talk by signaling through Toll-like receptor 4
2009
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