Citation Impact
Citing Papers
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
2009 StandoutNobel
GPCR Engineering Yields High-Resolution Structural Insights into β 2 -Adrenergic Receptor Function
2007 StandoutScienceNobel
Infectious enveloped RNA virus antigenic chimeras.
1992 StandoutNobel
Single-crystal x-ray diffraction structures of covalent organic frameworks
2018 StandoutScienceNobel
Csy4 relies on an unusual catalytic dyad to position and cleave CRISPR RNA
2012 StandoutNobel
Heparin-Protein Interactions
2002 Standout
Coupled 5′ Nucleotide Recognition and Processivity in Xrn1-Mediated mRNA Decay
2011 StandoutNobel
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Angiogenesis inhibition: A review
1994
Structural disorder throws new light on moonlighting
2005
Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis
1996 Standout
Ribosome-inactivating proteins from plants
1993
Quantitative Emergence of Hetero[4]rotaxanes by Template‐Directed Click Chemistry
2012 StandoutNobel
Making and Breaking Nucleic Acids: Two-Mg2+-Ion Catalysis and Substrate Specificity
2006
De novo protein design. I. in search of stability and specificity
1999 StandoutNobel
Identification of the residues in human CD4 critical for the binding of HIV
1989 StandoutNobel
Dynamic imine chemistry
2012 StandoutNobel
Structure and Conformational Changes in the C-terminal Domain of the β2-Adrenoceptor
2007 StandoutNobel
Vascular targeting—a new approach to the therapy of solid tumors
1994
Isolation of Angiopoietin-1, a Ligand for the TIE2 Receptor, by Secretion-Trap Expression Cloning
1996 Standout
Crystal structures of fusion proteins with large‐affinity tags
2003
A Genomic and Functional Inventory of Deubiquitinating Enzymes
2005 Standout
Antibody targeted drugs as cancer therapeutics
2006
Telomeres and telomerase: their mechanisms of action and the effects of altering their functions
2004 StandoutNobel
Potent antibody drug conjugates for cancer therapy
2009
Conservation, Variability and the Modeling of Active Protein Kinases
2007 StandoutNobel
DNA Damage, Aging, and Cancer
2009 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Breaking the chains: structure and function of the deubiquitinases
2009 Standout
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Template‐Directed Syntheses of Rigid Oligorotaxanes under Thermodynamic Control
2010 StandoutNobel
Role of Interaction of XPF with RPA in Nucleotide Excision Repair
2011
Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA
2004 StandoutNobel
Dynamic Combinatorial Chemistry Employing Boronic Acids/Boronate Esters Leads to Potent Oxygenase Inhibitors
2012 StandoutNobel
Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation
2020 StandoutNobel
From supramolecular chemistry towards constitutional dynamic chemistry and adaptive chemistry
2006 StandoutNobel
Nucleases: diversity of structure, function and mechanism
2010
Regulation of Human Separase by Securin Binding and Autocleavage
2002
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
Arming antibodies: prospects and challenges for immunoconjugates
2005
CLOCK deubiquitylation by USP8 inhibits CLK/CYC transcription in Drosophila
2012 StandoutNobel
A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein
2004 StandoutNobel
Dynamic donor–acceptor [2]catenanes
2007 StandoutNobel
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Kinetic and Thermodynamic Approaches for the Efficient Formation of Mechanical Bonds
2008 StandoutNobel
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Inhibition of malignant angiogenesis
1997
Recombinant Toxins for Cancer Treatment
1991 Science
Chemical Topology: Complex Molecular Knots, Links, and Entanglements
2011 StandoutNobel
HIV-Infected Cells Are Killed by rCD4-Ricin A Chain
1988 Science
New Strategies for Fluorescent Probe Design in Medical Diagnostic Imaging
2009 Standout
Positive Cooperativity in the Template-Directed Synthesis of Monodisperse Macromolecules
2012 StandoutNobel
Dynamic Transformation between Covalent Organic Frameworks and Discrete Organic Cages
2020 StandoutNobel
Molecular Mechanisms of Mammalian Global Genome Nucleotide Excision Repair
2005
Dynamic Combinatorial Chemistry
2006 Standout
The Complex Effects of Heparins on Cancer Progression and Metastasis in Experimental Studies
2001
Redox regulation of tyrosine kinase signalling: more than meets the eye
2019
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag
2009 StandoutNobel
Angiogenesis: Models and Modulators
1995
Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model
1998 StandoutScience
DNA origami protection and molecular interfacing through engineered sequence-defined peptoids
2020 StandoutNobel
In Vitro Analysis of the Role of Replication Protein A (RPA) and RPA Phosphorylation in ATR-mediated Checkpoint Signaling
2012 StandoutNobel
Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions
2003
Growth Factors and Cancer
1991 StandoutScience
Regulation of Mammalian O2Homeostasis by Hypoxia-Inducible Factor 1
1999 StandoutNobel
pH-Operated Nanopistons on the Surfaces of Mesoporous Silica Nanoparticles
2010 StandoutNobel
Immunotoxins for targeted cancer therapy
1998
Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes
2009
Redesigning Nature's Poisons to Create Anti-Tumor Reagents
1987 Science
Engineering Chemical Reactivity on Cell Surfaces Through Oligosaccharide Biosynthesis
1997 StandoutScienceNobel
Contribution of Linker Stability to the Activities of Anticancer Immunoconjugates
2008
Works of P.P. Knowles being referenced
Structure of an XPF endonuclease with and without DNA suggests a model for substrate recognition
2005
Crystallization of an intact GST-estrogen receptor hormone binding domain fusion protein
1998
Hepatotoxicity of immunotoxins made with saporin, a ribosome-inactivating protein fromSaponaria officinalis
1987
The Dual Mechanism of Separase Regulation by Securin
2002
aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization
2016
Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases
2007 Nature
The solution structure of the Josephin domain of ataxin-3: Structural determinants for molecular recognition
2005
Crystal structure of a gamma-herpes virus cyclin/cdk complex
2000
Improved antitumor effects of immunotoxins prepared with deglycosylated ricin A-chain and hindered disulfide linkages.
1988
Comparison of Two Anti-Thy 1.1-Abrin A-Chain Immunotoxins Prepared With Different Cross-Linking Agents: Antitumor Effects, In Vivo Fate, and Tumor Cell Mutants
1987
Heparin-steroid conjugates: new angiogenesis inhibitors with antitumor activity in mice.
1993
Evaluation of ricin A chain-containing immunotoxins directed against CD19 and CD22 antigens on normal and malignant human B-cells as potential reagents for in vivo therapy.
1988
Purification of ricin A1, A2, and B chains and characterization of their toxicity.
1986