Citation Impact
Citing Papers
Statistical significance for genomewide studies
2003 Standout
Hereditary desmoid disease due to a frameshift mutation at codon 1924 of the APC gene.
1996
Mismatch Repair-dependent Iterative Excision at Irreparable O6-Methylguanine Lesions in Human Nuclear Extracts
2006 StandoutNobel
Defects of the Mismatch Repair Gene MSH2 Are Implicated in the Development of Murine and Human Lymphoblastic Lymphomas and Are Associated With the Aberrant Expression of Rhombotin-2 (Lmo-2) and Tal-1 (SCL)
1997
Gastric cancer
2016 Standout
Mechanisms in Eukaryotic Mismatch Repair
2006 StandoutNobel
Gene expression profiling predicts clinical outcome of breast cancer
2002 StandoutNature
IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
2004 Standout
Distinct MutS DNA-binding Modes That Are Differentially Modulated by ATP Binding and Hydrolysis
2001 StandoutNobel
Base-excision repair of oxidative DNA damage
2007 StandoutNature
Demethylation of 3-Methylthymine in DNA by Bacterial and Human DNA Dioxygenases
2004 StandoutNobel
Pancreatic cancer
2004 Standout
Strand-specific Mismatch Repair in Mammalian Cells
1997 StandoutNobel
The β Sliding Clamp Binds to Multiple Sites within MutL and MutS
2006 StandoutNobel
Is gastric cancer part of the tumour spectrum of hereditary non-polyposis colorectal cancer? A molecular genetic study
2007
Physician assessment of family cancer history and referral for genetic evaluation in colorectal cancer patients
2004
Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease
1998
Guidelines for colorectal cancer screening and surveillance in moderate and high risk groups (update from 2002)
2010
Genetic instabilities in human cancers
1998 StandoutNature
Genetics of hereditary colorectal cancer
2005
Exome sequencing reveals three novel candidate predisposition genes for diffuse gastric cancer
2015
Hydrolytic function of Exo1 in mammalian mismatch repair
2014 StandoutNobel
HIF-1α Induces Genetic Instability by Transcriptionally Downregulating MutSα Expression
2005 StandoutNobel
Mismatch-, MutS-, MutL-, and Helicase II-dependent Unwinding from the Single-strand Break of an Incised Heteroduplex
1998 StandoutNobel
Endonucleolytic Function of MutLα in Human Mismatch Repair
2006 StandoutNobel
Cancer risk in mutation carriers of DNA-mismatch-repair genes
1999
Engraftment kinetics and hematopoietic chimerism after reduced-intensity conditioning with fludarabine and treosulfan before allogeneic stem cell transplantation
2007
Novel aspects of macromolecular repair and relationship to human disease
2004
Human Exonuclease I Is Required for 5′ and 3′ Mismatch Repair
2002 StandoutNobel
Structure of the Human MutSα DNA Lesion Recognition Complex
2007 StandoutNobel
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Ulcerative colitis
2012 Standout
DNA Polymerase δ Is Required for Human Mismatch Repair in Vitro
1997 StandoutNobel
Mutations Predisposing to Hereditary Nonpolyposis Colorectal Cancer
1997
Genetic alterations in breast cancer
1995
Hereditary Colorectal Cancer
2003 Standout
MutLα and Proliferating Cell Nuclear Antigen Share Binding Sites on MutSβ
2010 StandoutNobel
DNA mismatch repair gene mutations in 55 kindreds with verified or putative hereditary non-polyposis colorectal cancer
1996
Gastric cancer
2020 Standout
Differential Specificities and Simultaneous Occupancy of Human MutSα Nucleotide Binding Sites
2004 StandoutNobel
Isolation of MutSβ from Human Cells and Comparison of the Mismatch Repair Specificities of MutSβ and MutSα
1998 StandoutNobel
Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer
2000
Repair of Large Insertion/Deletion Heterologies in Human Nuclear Extracts Is Directed by a 5′ Single-strand Break and Is Independent of the Mismatch Repair System
1999 StandoutNobel
DNA-dependent Activation of the hMutSα ATPase
1998 StandoutNobel
New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative Group on HNPCC☆
1999 Standout
Molecular basis of HNPCC: Mutations of MMR genes
1997
DNA mismatch repair and cancer
2001
Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland
2000 Standout
A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: Meeting Highlights and Bethesda Guidelines
1997
DNA Repair Excision Nuclease Attacks Undamaged DNA
2001 StandoutNobel
Hereditary nonpolyposis colorectal cancer (Lynch syndrome): An updated review
1996
The MutL ATPase Is Required for Mismatch Repair
2000 StandoutNobel
A Defined Human System That Supports Bidirectional Mismatch-Provoked Excision
2004 StandoutNobel
Mechanism of 5′-Directed Excision in Human Mismatch Repair
2003 StandoutNobel
The genetic basis of colorectal cancer: Insights into critical pathways of tumorigenesis
2000
DNA Chain Length Dependence of Formation and Dynamics of hMutSα·hMutLα·Heteroduplex Complexes
2001 StandoutNobel
Pancreatic cancer
2011 Standout
Cancer of the Ovary
2004 Standout
Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell Transplantation
2009 Standout
Role of DNA Mismatch Repair Defects in the Pathogenesis of Human Cancer
2003
Lynch Syndrome Genes
2005
Cancer Cell Cycles
1996 StandoutScience
Inherited Susceptibility to Colorectal Cancer
2005
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
MSH2 andMLH1 mutations in sporadic replication error-positive colorectal carcinoma as assessed by two-dimensional DNA electrophoresis
1997
Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer
2003 Standout
PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance
2010 StandoutNobel
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
1998 Standout
URINARY TRACT CANCER AND HEREDITARY NONPOLYPOSIS COLORECTAL CANCER: RISKS AND SCREENING OPTIONS
1998
Brca2 is required for embryonic cellular proliferation in the mouse.
1997 StandoutNobel
Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC
1997 StandoutScience
Genetic susceptibility to non-polyposis colorectal cancer
1999
Allelotyping of ductal carcinoma in situ of the breast: deletion of loci on 8p, 13q, 16q, 17p and 17q.
1995
The Hereditary Nonpolyposis Colorectal Cancer Syndrome: Genetics and Clinical Implications
2003
Biallelic inactivation of hMLH 1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
1998 StandoutNobel
CpG island methylator phenotype in colorectal cancer
1999 Standout
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
Recommendations for the care of individuals with an inherited predisposition to Lynch syndrome: a systematic review.
2006
Biochemistry and genetics of eukaryotic mismatch repair.
1996
Works of PM Khan being referenced
Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis
1996
Persistence of host-type hematopoiesis after allogeneic bone marrow transplantation for leukemia is significantly related to the recipient's age and/or the conditioning regimen, but it is not associated with an increased risk of relapse
1994
Seven new mutations in hMSH2, an HNPCC gene, identified by denaturing gradient-gel electrophoresis.
1995
Allele loss patterns on chromosome 17q in 109 breast carcinomas indicate at least two distinct target regions.
1993