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Citing Papers

A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
Neuropharmacology of AMPA and kainate receptors
1998
Kainate receptors: Pharmacology, function and therapeutic potential
2008
Antiallodynic and Antihyperalgesic Effects of Selective Competitive GLUK5 (GluR5) Ionotropic Glutamate Receptor Antagonists in the Capsaicin and Carrageenan Models in Rats
2006
Structural, conformational, and stereochemical requirements of central excitatory amino acid receptors
1990
Ligands for Glutamate Receptors:  Design and Therapeutic Prospects
2000
Kainate receptor pharmacology and physiology
1999
In Vitro Characterization of 5-Carboxyl-2,4-di-benzamidobenzoic Acid (NS3763), a Noncompetitive Antagonist of GLUK5 Receptors
2004
Kainate GluR5 receptor subtype mediates the nociceptive response to formalin in the rat
1998
Cingulate NMDA NR2B receptors contribute to morphine-induced analgesic tolerance
2008
Effects of the 2-amino-3-hydroxy-5-methyl-4-isoxazole-proprionic acid/kainate antagonist LY293558 on spontaneous and evoked postoperative pain
2000
New developments in the molecular pharmacology of α-amino-3-hydroxy-5-methyl-4-isoxazole propionate and kainate receptors
1996
Substantia gelatinosa neurones hyperpolarized in vitro by enkephalin
1983 Nature
Glutamate receptor ion channels
2005 Standout
G Protein–Coupled Receptor Kinase Mediates Desensitization of Norepinephrine-Induced Ca2+ Channel Inhibition
1996 StandoutNobel
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
2010 Standout
A monoclonal antibody raised against an [Na+K+]coupled l‐glutamate transporter purified from rat brain confirms glial cell localization
1993
Characterization of the binding of two novel glycine site antagonists to cloned NMDA receptors: evidence for two pharmacological classes of antagonists
2000
Distributions of mRNAs for alpha‐2 adrenergic receptor subtypes in rat brain: An in situ hybridization study
1993
Glutamate-operated channels: Developmentally early and mature forms arise by alternative splicing
1991
Neurologic Sequelae of Domoic Acid Intoxication Due to the Ingestion of Contaminated Mussels
1990
Domoic acid poisoning and mussel-associated intoxication: Preliminary investigations into the response of mice and rats to toxic mussel extract
1989
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Glutamate uptake
2001 Standout
An [Na+ + K+]coupledl-glutamate transporter purified from rat brain is located in glial cell processes
1992
Piezo2 is required for Merkel-cell mechanotransduction
2014 StandoutNatureNobel
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
2011 StandoutNature
An Outbreak of Toxic Encephalopathy Caused by Eating Mussels Contaminated with Domoic Acid
1990
Altered expression of glutamate transporter GLAST mRNA in rat brain after photochemically induced focal ischemia
1998
Acromelic acid, a novel kainate analogue, induces long-lasting paraparesis with selective degeneration of interneurons in the rat spinal cord
1992
Ultrasensitive fluorescent proteins for imaging neuronal activity
2013 StandoutNature
The high affinity uptake system for excitatory amino acids in the brain
1994
Allosteric modulators of NR2B‐containing NMDA receptors: molecular mechanisms and therapeutic potential
2009
Domoic Acid Neurotoxicity in Cultured Cerebellar Granule Neurons Is Mediated Predominantly by NMDA Receptors that Are Activated as a Consequence of Excitatory Amino Acid Release
1997
Interaction of domoic acid and several derivatives with kainic acid and AMPA binding sites in rat brain
1992
Domoic acid: A dementia-inducing excitotoxic food poison with kainic acid receptor specificity
1990
Molecular and cellular mechanisms of general anaesthesia
1994 StandoutNature
Assembly and Ligand Binding Properties of the Water-soluble Extracellular Domains of the Glutamate Receptor 1 Subunit
2001
Ketamine: an update on the first twenty-five years of clinical experience
1989
Imaging terminals of Aplysia sensory neurons demonstrates role of enhanced Ca2+ influx in presynaptic facilitation
1993 StandoutNatureNobel
Fast and slow components of unitary EPSCs on stellate cells elicited by focal stimulation in slices of rat visual cortex.
1992 Nobel
Structure/activity relations of N-methyl-d-aspartate receptor ligands as studied by their inhibition of [3H]d2-amino-5-phosphonopentanoic acid binding in rat brain membranes
1988
The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion
1997 StandoutNatureNobel
Novel N1-(benzyl)cinnamamidine derived NR2B subtype-selective NMDA receptor antagonists
2003
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
Dose escalating safety study of CNS 5161 HCl, a new neuronal glutamate receptor antagonist (NMDA) for the treatment of neuropathic pain
2007
A conformationally restricted analogue of l-glutamate, the (2S,3R,4S) isomer of l-α(carboxycyclopropyl)glycine, activates the NMDA-type receptor more markedly than NMDA in the isolated rat spinal cord
1989
Memantine is a clinically well tolerated N-methyl-d-aspartate (NMDA) receptor antagonist—a review of preclinical data
1999
Pharmacological agents acting at subtypes of metabotropic glutamate receptors
1999
Afferents to the median raphe nucleus of the rat: Retrograde cholera toxin and wheat germ conjugated horseradish peroxidase tracing, and selectived-[3H]aspartate labelling of possible excitatory amino acid inputs
1990
Clonidine and the hyper-responsiveness of dorsal horn neurones following morphine withdrawal in the spinal cat
1987
The history of the pharmacology and cloning of ionotropic glutamate receptors and the development of idiosyncratic nomenclature
2008
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Bioenergetics and glutamate excitotoxicity
1996
Glutamate-based therapeutic approaches: NR2B receptor antagonists
2005
Analysis of NMDA Receptors in the Human Spinal Cord
1997
Behavioral and autonomic correlates of the tactile evoked allodynia produced by spinal glycine inhibition: effects of modulatory receptor systems and excitatory amino acid antagonists
1989
Targeting the NMDA Receptor Subunit NR2B for the Treatment of Neuropathic Pain
2009
The Sensory Neurons of Touch
2013
Expression of the glutamate transporter GLT1 in neural cells of the rat central nervous system: Non-radioactive in situ hybridization and comparative immunocytochemistry
1996
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Metabotropic glutamate receptors: electrophysiological properties and role in plasticity
1999
Dynorphin displaces binding at the glycine site of the NMDA receptor in the rat striatum
2006
Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain
1988 StandoutNature
Kainate receptors
2006
Molecular determinants of ligand discrimination in the glutamate-binding pocket of the NMDA receptor
2004
Continuous subcutaneous administration of the N -methyl-D-aspartic acid (NMDA) receptor antagonist ketamine in the treatment of post-herpetic neuralgia
1995
Expression of the kynurenine pathway enzyme tryptophan 2,3-dioxygenase is increased in the frontal cortex of individuals with schizophrenia
2004
Antinociceptive effects of the marine snail peptides conantokin-G and conotoxin MVIIA alone and in combination in rat models of pain
2008
Stress Preferentially Increases Extraneuronal Levels of Excitatory Amino Acids in the Prefrontal Cortex: Comparison to Hippocampus and Basal Ganglia
1993
NMDA receptor pathways as drug targets
2002
Fyn kinase‐mediated phosphorylation of NMDA receptor NR2B subunit at Tyr1472 is essential for maintenance of neuropathic pain
2005
Kainate receptors are involved in synaptic plasticity
1999 Nature
NMDA Receptor Subunit-Dependent [Ca2+] Signaling in Individual Hippocampal Dendritic Spines
2005
The Role of N-Methyl-d-Aspartate (NMDA) Receptors in Pain: A Review
2003
Acute nociception mediated by hindpaw P2X receptor activation in the rat
1997
The immunocytochemical localization of enkephalin in the central nervous system of the rat
1981
EFFECTS OF KETAMINE AND THREE OTHER ANAESTHETICS ON SPINAL REFLEXES AND INHIBITIONS IN THE CAT
1984
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Actions of opiates upon single unit activity in the cortex of naive and tolerant rats
1976
Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2
1999 StandoutScienceNobel
Effects of optical isomers of ketamine on excitation of cat and rat spinal neurones by amino acids and acetylcholine
1982
Chapter 28 Sites of action of opiates in production of analgesia
1988
Mapping the Binding Site of the Neuroprotectant Ifenprodil on NMDA Receptors
2002
Two endogenous neuropeptides modulate the gill and siphon withdrawal reflex in Aplysia by presynaptic facilitation involving cAMP-dependent closure of a serotonin-sensitive potassium channel.
1984 StandoutNobel
Opiate analgesics inhibit substance P release from rat trigeminal nucleus
1977 Nature
Immunocytochemistry with internally labeled monoclonal antibodies.
1982 StandoutNobel
Ethanol increases single unit activity in the inferior olivary nucleus
1986
Opiate agonist-antagonist interaction at cortical neurones of naive and tolerant/dependent rats
1974
(+)-MCPG Blocks Induction of LTP in CA1 of Rat Hippocampus via Agonist Action at an mGluR Group II Receptor
1998
Neurotrophic and Neurotoxic Effects of Amyloid β Protein: Reversal by Tachykinin Neuropeptides
1990 StandoutScience
5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system.
1989 StandoutNobel
Glycine potentiates the NMDA response in cultured mouse brain neurons
1987 StandoutNature
Receptors for the excitatory amino acids in the mammalian central nervous system
1983
The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N‐methyl‐aspartate
1983
Long-Term Potentiation--A Decade of Progress?
1999 StandoutScience
Calcium and the control of synaptic strength by learning
1981 StandoutNatureNobel
Spatial distribution of calcium channels and cytosolic calcium transients in growth cones and cell bodies of sympathetic neurons.
1988 StandoutNobel
Neural computation by concentrating information in time.
1987 StandoutNobel
The antagonism of amino acid‐induced excitations of rat hippocampal CA1 neurones in vitro.
1983
Presynaptic inhibition in Aplysia involves a decrease in the Ca2+ current of the presynaptic neuron.
1980 StandoutNobel
The excitant amino acids glutamic and aspartic acid as transmitter candidates in the vertebrate central nervous system
1978
Cardiovascular Regulation in Mice Lacking α 2 -Adrenergic Receptor Subtypes b and c
1996 StandoutScienceNobel
Structural Determinants of Ion Flow Through Recombinant Glutamate Receptor Channels
1991 StandoutScienceNobel
Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5
1986 StandoutNature
The electron microscopic localization of methionine-enkephalin within the superficial layers (I and II) of the spinal cord
1980
Magnesium gates glutamate-activated channels in mouse central neurones
1984 StandoutNature
NR2B subtype-selective NMDA receptor antagonists: 2001 – 2004
2005
Single glutamate‐activated channels recorded from locust muscle fibres with perfused patch‐clamp electrodes
1981
Barbiturates: Their in vivo effects and potential biochemical mechanisms
1982
Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors.
1992 StandoutNobel
Neural Science
2000 StandoutNobel
Structure-activity relations for the neurotoxicity of kainic acid derivatives and glutamate analogues
1978
Synaptic Vesicular Localization and Exocytosis ofl-Aspartate in Excitatory Nerve Terminals: A Quantitative Immunogold Analysis in Rat Hippocampus
1998
THE EFFECTS OF A SERIES OF ω‐PHOSPHONIC α‐CARBOXYLIC AMINO ACIDS ON ELECTRICALLY EVOKED AND EXCITANT AMINO ACID‐INDUCED RESPONSES IN ISOLATED SPINAL CORD PREPARATIONS
1982
Enkephalin inhibits release of substance P from sensory neurons in culture and decreases action potential duration.
1979
ACTION OF THE NEUROTOXIN KAINIC ACID ON HIGH AFFINITY UPTAKE OF l‐GLUTAMIC ACID IN RAT BRAIN SLICES
1979
Cellular and Molecular Mechanisms of Drug Dependence
1988 StandoutScience
The Glutamate Receptor Ion Channels
1999 Standout
Acidic amino acid binding sites in mammalian neuronal membranes: their characteristics and relationship to synaptic receptors
1984
Steroid Hormone Metabolites Are Barbiturate-Like Modulators of the GABA Receptor
1986 StandoutScience
Properties and distribution of ionic conductances generating electroresponsiveness of mammalian inferior olivary neurones in vitro.
1981
The Intrinsic Electrophysiological Properties of Mammalian Neurons: Insights into Central Nervous System Function
1988 StandoutScience
Tail shock produces inhibition as well as sensitization of the siphon-withdrawal reflex of Aplysia: possible behavioral role for presynaptic inhibition mediated by the peptide Phe-Met-Arg-Phe-NH2.
1987 StandoutNobel
Blockade of NMDA Receptors and Apoptotic Neurodegeneration in the Developing Brain
1999 StandoutScience
Pathophysiology of Sleep Apnea
2010 Standout
Excitatory Amino Acid Transmitters
1981 Standout
Microinjection of morphine into the periaqueductal gray evokes the release of serotonin from spinal cord
1979
Dependence in the absence of tolerance to morphine
1984
The glutamate receptor ion channels.
1999
Iontophoretic application of opiates to the locus coeruleus
1977
The mechanism of action for the block of NMDA receptor channels by the opioid peptide dynorphin
1995
Enzymatic aminoacylation of tRNA with unnatural amino acids
2006 StandoutNobel
Oxidative Stress, Glutamate, and Neurodegenerative Disorders
1993 StandoutScience
The growth cones of Aplysia sensory neurons: Modulation by serotonin of action potential duration and single potassium channel currents
1986 StandoutNobel
D 1 and D 2 Dopamine Receptor-regulated Gene Expression of Striatonigral and Striatopallidal Neurons
1990 StandoutScience
Characterization of specific, high-affinity binding sites for l-[3H]glutamic acid in rat brain membranes
1980
Electrophysiology of mammalian inferior olivary neurones in vitro. Different types of voltage‐dependent ionic conductances.
1981
Substance P as a Transmitter Candidate
1980
Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones
1984 StandoutNature
The physiology of excitatory amino acids in the vertebrate central nervous system
1987 Standout
Serotonin and cyclic AMP close single K+ channels in Aplysia sensory neurones
1982 StandoutNatureNobel
Ionic currents and firing patterns of mammalian vagal motoneurons In vitro
1985
In situ injection of kainic acid: A new method for selectively lesioning neuronal cell bodies while sparing axons of passage
1978
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release
2017 StandoutNobel
PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS
1997 Standout
Neurotransmitters decrease the calcium component of sensory neurone action potentials
1978 Nature
Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation
1983 StandoutScience
Molecular Diversity of Glutamate Receptors and Implications for Brain Function
1992 StandoutScience
Cellular uptake disguises action of L‐glutamate on N‐methyl‐D‐aspartate receptors: With an appendix: Diffusion of transported amino acids into brain slices
1985
Differential synaptic localization of the glutamate transporter EAAC1 and glutamate receptor subunit gluR2 in the rat hippocampus
2000
Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes
1992 StandoutScienceNobel

Works of P.M. Headley being referenced

Spinal antinociceptive actions of μ‐ and κ‐opioids: the importance of stimulus intensity in determining ‘selectivity’ between reflexes to different modalities of noxious stimulus
1989
Autoradiographic and electrophysiological evidence for excitatory amino acid transmission in the periaqueductal gray projection to nucleus raphe magnus in the rat
1988
Antagonism of mGlu Receptors and Potentiation of EPSCs at Rat Spinal Motoneurones In Vitro
1997
Spinal antinociceptive actions and naloxone reversibility of intravenous μ‐ and κ‐opioids in spinalized rats: potency mismatch with values reported for spinal administration
1989
Memantine selectively depresses NMDA receptor-mediated responses of rat spinal neurones in vivo
1994
Membrane Characteristics and Synaptic Responsiveness of Superficial Dorsal Horn Neurons in a Slice Preparation of Adult Rat Spinal Cord
1989
AMPA receptors have an equal role in spinal nociceptive and non-nociceptive transmission
1994
A comparison of intravenous NBQX and GYKI 53655 as AMPA antagonists in the rat spinal cord
1994
Excitatory amino acids and synaptic transmission: the evidence for a physiological function
1990
Metabotropic glutamate receptor antagonists, like GABAB antagonists, potentiate dorsal root-evoked excitatory synaptic transmission at neonatal rat spinal motoneurons in vitro
1997
NMDA receptor antagonists as analgesics: focus on the NR2B subtype
2001
An excitatory amino acid projection from ventromedial hypothalamus to periaqueductal gray in the rat: Autoradiographic and electrophysiological evidence
1988
A comparison of the effects of selective metabotropic glutamate receptor agonists on synaptically evoked whole cell currents of rat spinal ventral horn neurones in vitro
1995
Actions of kainate and AMPA selective glutamate receptor ligands on nociceptive processing in the spinal cord
1998
At which ‘sigma’ site are the spinal actions of ketamine mediated?
1988
Effects of excitants on neurones and cerebellar-evoked field potentials in the inferior olivary complex of the rat
1973
Studies on field potentials and on single cells in the inferior olivary complex of the rat
1976
Domoic and quisqualic acids as potent amino acid excitants of frog and rat spinal neurones
1975 Nature
Effect of nuciferine on the chemical excitation of Renshaw cells in the rat.
1973
Electrical interaction between motoneurons and afferent terminals in cat spinal cord
1979
Selective reduction by noradrenaline and 5-hydroxytryptamine of nociceptive responses of cat dorsal horn neurones
1978
The sensitivity of rat spinal interneurones and Renshaw cells to L-glutamate and L-aspartate
1976
The effects of morphine, etorphine and sinomenine on the chemical sensitivity and synaptic responses of Renshaw cells and other spinal neurones in the rat
1974
Drug-induced rhythmical activity in the inferior olivary complex of the rat
1976
SUPPRESSION OF TRANSMISSION OF NOCICEPTIVE IMPULSES BY MORPHINE: SELECTIVE EFFECTS OF MORPHINE ADMINISTERED IN THE REGION OF THE SUBSTANTIA GELATINOSA
1977
Novel systemically active antagonists of the glycine site of the N-methyl-D-aspartate receptor: electrophysiological, biochemical and behavioral characterization.
1997
Pharmacological studies on facial motoneurones in the rat
1977
NMDA Antagonists and Neuropathic Pain - Multiple Drug Targets and Multiple Uses
2005
ENKEPHALINS AND DORSAL HORN NEURONES OF THE CAT: EFFECTS ON RESPONSES TO NOXIOUS AND INNOCUOUS SKIN STIMULI
1977
Lack of effect by substance P at sites in the substantia gelatinosa where met-enkephalin reduces the transmission of nociceptive impulses
1979
Morphine, enkephalin and the substantia gelatinosa
1976 Nature
Acetylcholine receptors on Renshaw cells of the rat
1975
The role of N‐methylaspartate receptors in mediating responses of rat and cat spinal neurones to defined sensory stimuli.
1987
STRUCTURE‐ACTIVITY RELATIONS OF EXCITATORY AMINO ACIDS ON FROG AND RAT SPINAL NEURONES
1976
Selective antagonism by D-α-aminoadipate of amino acid and synaptic excitation of cat spinal neurons
1978
ACETYLCHOLINE‐SENSITIVE CELLS IN THE CAUDAL MEDULLA OF THE RAT: DISTRIBUTION, PHARMACOLOGY AND EFFECTS OF PENTOBARBITONE
1975
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