Standout Papers
Citation Impact
Citing Papers
SNARE Function Analyzed in Synaptobrevin/VAMP Knockout Mice
2001 StandoutScienceNobel
Rab1b regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments.
1991
Synaptoporin, a novel putative channel protein of synaptic vesicles
1990
Tetanus toxin action: Inhibition of neurotransmitter release linked to synaptobrevin proteolysis
1992 StandoutNobel
Small GTP-binding proteins and their role in transport
1991
Defective recycling of synaptic vesicles in synaptotagmin mutants of Caenorhabditis elegans
1995 StandoutNatureNobel
A post-docking role for active zone protein Rim
2001
Evidence That the Rab3a-binding Protein, Rabphilin3a, Enhances Regulated Secretion.
1995
Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin
1993 StandoutNatureNobel
Structural Basis of Rab Effector Specificity
1999
Differential expression of the p65 gene family
1991
Cellugyrin, a Novel Ubiquitous Form of Synaptogyrin That Is Phosphorylated by pp60c-
1998 StandoutNobel
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Comparison of the Effects on Secretion in Chromaffin and PC12 Cells of Rab3 Family Members and Mutants
1999
The GTPase superfamily: a conserved switch for diverse cell functions
1990 StandoutNature
ADP-Ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: A novel role for a GTP-binding protein
1991
Rab proteins and the road maps for intracellular transport
1993
A small GTP-binding protein dissociates from synaptic vesicles during exocytosis
1991 Nature
Exocytotic and endocytotic membrane traffic in neurons
1991
A Functional Role for GTP-Binding Proteins in Synaptic Vesicle Cycling
1993 Science
Inhibition of RabSB expression attenuates Ca2+-dependent exocytosis in rat anterior pituitary cells
1993 Nature
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
1994 StandoutScienceNobel
Rab proteins
1998
Characterization of the human synaptogyrin gene family
1998
Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25
1993 StandoutNatureNobel
Synaptogyrins Regulate Ca2+-dependent Exocytosis in PC12 Cells
1999 StandoutNobel
Essential Roles in Synaptic Plasticity for Synaptogyrin I and Synaptophysin I
1999 StandoutNobel
The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion
1997 StandoutNatureNobel
SNAP receptors implicated in vesicle targeting and fusion
1993 StandoutNatureNobel
Storage and release of neurotransmitters
1993
Synaptotagmin I functions as a calcium regulator of release probability
2001 StandoutNatureNobel
The C2 Domains of Rabphilin3A Specifically Bind Phosphatidylinositol 4,5-Bisphosphate Containing Vesicles in a Ca2+-dependent Manner
1998
Molecular dissection of the secretory pathway
1992 Nature
Ca2+-dependent and -independent activities of neural and non-neural synaptotagmins
1995 StandoutNatureNobel
Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C
1990 Nature
Purification of component A of Rab geranylgeranyl transferase: Possible identity with the choroideremia gene product
1992 StandoutNobel
Double In Situ Hybridization Reveals Overlapping Neuronal Populations Expressing the Low Molecular Weight GTPases Rab3a and Rab3b in Rat Brain
1995
Hypervariable C-termmal domain of rab proteins acts as a targeting signal
1991 Nature
Differential expression ofrab3 isoforms in oligodendrocytes and astrocytes
1996
rab3A attachment to the synaptic vesicle membrane mediated by a conserved polyisoprenylated carboxy-terminal sequence
1991 StandoutNobel
Multiple intercellular signalling systems control the development of the Caenorhabditis elegans vulva
1991 StandoutNatureNobel
Exocytotic fusion is activated by Rab3a peptides
1992 Nature
The RIM/NIM Family of Neuronal C2 Domain Proteins
2000 StandoutNobel
Substitution of three amino acids switches receptor specificity of Gqα to that of Giα
1993 StandoutNatureNobel
SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER
1993 StandoutNatureNobel
Proteins of synaptic vesicles involved in exocytosis and membrane recycling
1991
The syntaxin family of vesicular transport receptors
1993
Systematic analysis of genes required for synapse structure and function
2005 StandoutNatureNobel
RIM1α is required for presynaptic long-term potentiation
2002 StandoutNatureNobel
Physical and Functional Interaction of Rabphilin-3A with α-Actinin
1996
Synaptic Vesicle Traffic: Rush Hour in the Nerve Terminal
1993
Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein
1993 StandoutNatureNobel
rab5 controls early endosome fusion in vitro
1991
Essential functions of synapsins I and II in synaptic vesicle regulation
1995 StandoutNatureNobel
The C. elegans unc-18 gene encodes a protein expressed in motor neurons
1993
The role of Rab3A in neurotransmitter release
1994 StandoutNatureNobel
Synaptic targeting of rabphilin-3A, a synaptic vesicle Ca2+/phospholipid-binding protein, depends on rab3A/3C
1994 StandoutNobel
The synaptic vesicle cycle: a cascade of protein–protein interactions
1995 StandoutNatureNobel
Synaptic Vesicles and Exocytosis
1994
Mechanisms of intracellular protein transport
1994 StandoutNatureNobel
Localization Versus Function of Rab3 Proteins
2002 StandoutNobel
STED microscopy reveals that synaptotagmin remains clustered after synaptic vesicle exocytosis
2006 StandoutNatureNobel
RIM1α forms a protein scaffold for regulating neurotransmitter release at the active zone
2002 StandoutNatureNobel
Synaptic vesicle membrane proteins interact to form a multimeric complex.
1992
Relative properties and localizations of synaptic vesicle protein isoforms: the case of the synaptophysins
1993
Small GTP-Binding Proteins
2001 Standout
Nonneuronal expression of Rab3A: induction during adipogenesis and association with different intracellular membranes than Rab3D.
1995
Exo-endocytotic recycling of synaptic vesicles in developing processes of cultured hippocampal neurons
1992
Colocalization of synaptophysin with transferrin receptors: implications for synaptic vesicle biogenesis.
1991
Membrane fusion machinery: Insights from synaptic proteins
1993 StandoutNobel
The small GTP-binding protein rab4 is associated with early endosomes.
1991
Two functionally different domains of rabphilin-3A, Rab3A p25/smg p25A-binding and phospholipid- and Ca(2+)-binding domains.
1993
Domain structure of synaptotagmin (p65)
1991 StandoutNobel
Specific association of the proto-oncogene product pp60c-src with an intracellular organelle, the PC12 synaptic vesicle
1992 Nobel
Coat Proteins and Vesicle Budding
1996 StandoutScienceNobel
Purification and expression of gCap39. An intracellular and secreted Ca2(+)-dependent actin-binding protein enriched in mononuclear phagocytes.
1990 StandoutNobel
Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP-binding protein related to synaptotagmin.
1993
Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF
1992 StandoutNatureNobel
A mammalian inhibitory GDP/GTP exchange protein (GDP dissociation inhibitor) for smg p25A is active on the yeast SEC4 protein.
1991
C terminus of the small GTP-binding protein smg p25A contains two geranylgeranylated cysteine residues and a methyl ester.
1991
Caenorhabditis elegans rab-3Mutant Synapses Exhibit Impaired Function and Are Partially Depleted of Vesicles
1997 StandoutNobel
Rabphilin-3A is associated with synaptic vesicles through a vesicle protein in a manner independent of Rab3A
1994
Rab3C is a synaptic vesicle protein that dissociates from synaptic vesicles after stimulation of exocytosis
1994 StandoutNobel
A rab protein regulates the localization of secretory granules in AtT-20 cells.
1993
Novel SCAMPs Lacking NPF Repeats: Ubiquitous and Synaptic Vesicle-Specific Forms Implicate SCAMPs in Multiple Membrane-Trafficking Functions
2000 StandoutNobel
SVOP, an Evolutionarily Conserved Synaptic Vesicle Protein, Suggests Novel Transport Functions of Synaptic Vesicles
1998 StandoutNobel
Regulation of the GTPase activity of the ras-like protein p25rab3A. Evidence for a rab3A-specific GAP.
1991
n-Sec1: a neural-specific syntaxin-bindingprotein.
1994
Synaptobrevin binding to synaptophysin: a potential mechanism for controlling the exocytotic fusion machine.
1995
Rabphilin Knock-Out Mice Reveal That Rabphilin Is Not Required for Rab3 Function in Regulating Neurotransmitter Release
1999 StandoutNobel
The Cellular Functions of Small GTP-Binding Proteins
1990 Science
Rab3A and Rab3D Control the Total Granule Number and the Fraction of Granules Docked at the Plasma Membrane in PC12 Cells
2000
Insulin and okadaic acid induce Rab4 redistribution in adipocytes.
1993
Regulation of the GTPase cycle of the neuronally expressed Ras-like GTP-binding protein Rab3A.
1993
Protein Sorting by Transport Vesicles
1996 StandoutScienceNobel
Removal of Rab GTP-binding proteins from Golgi membranes by GDP dissociation inhibitor inhibits inter-cisternal transport in the Golgi stacks.
1994 StandoutNobel
Clathrin-coated vesicles in nervous tissue are involved primarily in synaptic vesicle recycling.
1992
Structure of the murine rab3A gene: correlation of genomic organization with antibody epitopes
1993 StandoutNobel
Rab3 reversibly recruits rabphilin to synaptic vesicles by a mechanism analogous to raf recruitment by ras.
1996 StandoutNobel
Synaptotagmin: a Calcium Sensor on the Synaptic Vesicle Surface
1992 StandoutScienceNobel
The Role of GTP-Binding Proteins in Transport Along the Exocytic Pathway
1993
Association of Rab3A with synaptic vesicles at late stages of the secretory pathway.
1991
Characterization of Rab3A, Rab3B and Rab3C: different biochemical properties and intracellular localization in bovine chromaffin cells
1997
Members of the VAMP family of synaptic vesicle proteins are components of glucose transporter-containing vesicles from rat adipocytes.
1992
Membrane Fusion: Grappling with SNARE and SM Proteins
2009 StandoutScienceNobel
Pantophysin is a ubiquitously expressed synaptophysin homologue and defines constitutive transport vesicles.
1996
Structure and expression of the rat inositol 1,4,5-trisphosphate receptor.
1990 StandoutNobel
Cloning of a Rab3 isotype predominantly expressed in adipocytes.
1992
Rabphilin-3A, a Putative Target Protein for smg p25A/rab3A p25 Small GTP-Binding Protein Related to Synaptotagmin
1993
The GTPase Rab3a negatively controls calcium-dependent exocytosis in neuroendocrine cells.
1994
GTP cleavage by the small GTP-binding protein Rab3A is associated with exocytosis of synaptic vesicles induced by alpha-latrotoxin.
1994
Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion
2000 StandoutScienceNobel
Structure of synaptogyrin (p29) defines novel synaptic vesicle protein.
1995 StandoutNobel
Synaptic Vesicle Phosphoproteins and Regulation of Synaptic Function
1993 Science
Mediation of the Attachment or Fusion Step in Vesicular Transport by the GTP-Binding Ypt1 Protein
1991 Science
The molecular machinery for secretion is conserved from yeast to neurons.
1993
Rab3A GTPase-activating protein-inhibiting activity of Rabphilin-3A, a putative Rab3A target protein.
1993
A synthetic peptide of the rab3a effector domain stimulates amylase release from permeabilized pancreatic acini.
1992
Secretory carrier membrane proteins 31-35 define a common protein composition among secretory carrier membranes.
1991
Works of P.M. Burger being referenced
P29: a novel tyrosine-phosphorylated membrane protein present in small clear vesicles of neurons and endocrine cells.
1990
rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles.
1990 StandoutNobel