Citation Impact
Citing Papers
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
2001 StandoutScienceNobel
HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing
2001 StandoutScienceNobel
Lipid Rafts As a Membrane-Organizing Principle
2009 StandoutScience
Taking Cell-Matrix Adhesions to the Third Dimension
2001 StandoutScience
Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles
2007
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
Rationally Designed Integrin β3 Mutants Stabilized in the High Affinity Conformation
2008 StandoutNobel
Pleiotropic Coupling of G Protein-coupled Receptors to the Mitogen-activated Protein Kinase Cascade
1999 StandoutNobel
Modulation of Integrin Activation by an Entropic Spring in the β-Knee
2010 StandoutNobel
Rac1 Activity Is Required for the Activation of Hypoxia-inducible Factor 1
2001 StandoutNobel
The Putative Vitamin K-dependent γ-Glutamyl Carboxylase Internal Propeptide Appears to Be the Propeptide Binding Site
2002
Cell Death Mechanisms and the Immune System
1991
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
2001 StandoutNobel
The Clinical Sequelae of Intravascular Hemolysis and Extracellular Plasma Hemoglobin
2005 Standout
Membrane-proximal α/β Stalk Interactions Differentially Regulate Integrin Activation
2005
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2
2004 StandoutNature
Integrin activation and structural rearrangement
2002
Assembly of macromolecular pores by immune defense systems
1991
Paroxysmal Nocturnal Hemoglobinuria
1992
Are changes in integrin affinity and conformation overemphasized?
1998
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
2012 StandoutNatureNobel
Calcineurin Promotes Hypoxia-inducible Factor 1α Expression by Dephosphorylating RACK1 and Blocking RACK1 Dimerization
2007 StandoutNobel
Two conformations of the integrin A-domain (I-domain): a pathway for activation?
1995
Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura
2001 StandoutNature
Thrombin signalling and protease-activated receptors
2000 StandoutNature
Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila
2005 StandoutNobel
DANCE, a Novel Secreted RGD Protein Expressed in Developing, Atherosclerotic, and Balloon-injured Arteries
1999 StandoutNobel
Structure and function of the Entamoeba histolytica Gal/GalNAc lectin
2002
Yin and Yang: complement activation and regulation in Alzheimer’s disease
2003
The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families
1998 StandoutNobel
Mutation in blood coagulation factor V associated with resistance to activated protein C
1994 StandoutNature
Inside-out integrin signalling
1992
Oxidative lipidomics of apoptosis: redox catalytic interactions of cytochrome c with cardiolipin and phosphatidylserine
2004
Stem cells, ageing and the quest for immortality
2006 StandoutNature
Effect of Eculizumab on Hemolysis and Transfusion Requirements in Patients with Paroxysmal Nocturnal Hemoglobinuria
2004
The Conserved Membrane-proximal Region of an Integrin Cytoplasmic Domain Specifies Ligand Binding Affinity
1995
Topography of Ligand-induced Binding Sites, Including a Novel Cation-sensitive Epitope (AP5) at the Amino Terminus, of the Human Integrin β3 Subunit
1995
Identification of the haemoglobin scavenger receptor
2001 StandoutNature
Sensing the environment: a historical perspective on integrin signal transduction
2002
Breaking the Integrin Hinge
1996
Familial intrahepatic cholestasis 1: Studies of localization and function
2001
Alzheimer's Disease
2010 Standout
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Programmable Cell Adhesion Encoded by DNA Hybridization
2005 StandoutNobel
Adhesive signaling in platelets
1994
Selection of Mutant CHO Cells with Constitutive Activation of the HIF System and Inactivation of the von Hippel-Lindau Tumor Suppressor
2001 StandoutNobel
Protein tyrosine phosphorylation and the adhesive functions of platelets
1991
Antigen‐presenting cell exosomes are protected from complement‐mediated lysis by expression of CD55 and CD59
2003
Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis
2001 Standout
Cell adhesion in vascular biology. New insights into integrin-ligand interaction.
1997
Amoebiasis
2003 Standout
Hypoxia-inducible factor-1α-induced differentiation of myeloid leukemic cells is its transcriptional activity independent
2007
Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
1994 Standout
Integrins
2002 Standout
Integrin Activation by Dithiothreitol or Mn2+ Induces a Ligand-occupied Conformation and Exposure of a Novel NH2-terminal Regulatory Site on the β1Integrin Chain
1998
Insights into integrin-ligand binding and activation from the first crystal structure.
2002
Spermidine/Spermine N1-Acetyltransferase-1 Binds to Hypoxia-inducible Factor-1α (HIF-1α) and RACK1 and Promotes Ubiquitination and Degradation of HIF-1α
2007 StandoutNobel
Cell Migration: Integrating Signals from Front to Back
2003 StandoutScience
Annexin V as a probe of aminophospholipid exposure and platelet membrane vesiculation: a flow cytometry study showing a role for free sulfhydryl groups
1993
Platelet-derived microparticles associate with fibrin during thrombosis
1996
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.
1992 StandoutNobel
Long range propagation of conformational changes in integrin alpha IIb beta 3.
1993
Pathologic effects of plasma from patients with thrombotic thrombocytopenic purpura on platelets and cultured vascular endothelial cells
1982
Activation of HIF1α ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex
2000
Functional rafts in cell membranes
1997 StandoutNature
Lymphocyte Homing and Homeostasis
1996 StandoutScience
Integrins: Versatility, modulation, and signaling in cell adhesion
1992 Standout
Complement proteins C5b-9 cause release of membrane vesicles from the platelet surface that are enriched in the membrane receptor for coagulation factor Va and express prothrombinase activity.
1988
Appendage Regeneration in Adult Vertebrates and Implications for Regenerative Medicine
2005 Science
Mutation of a ligand binding domain of beta 3 integrin. Integral role of oxygenated residues in alpha IIb beta 3 (GPIIb-IIIa) receptor function.
1994
Crystal Structure of the Extracellular Segment of Integrin αVβ3
2001 Science
High shear stress can initiate both platelet aggregation and shedding of procoagulant containing microparticles
1996
Structure of Staphylococcal α-Hemolysin, a Heptameric Transmembrane Pore
1996 StandoutScience
Role of virion-associated glycosylphosphatidylinositol-linked proteins CD55 and CD59 in complement resistance of cell line-derived and primary isolates of HIV-1.
1995
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
2002 StandoutNobel
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Complementary Roles for Receptor Clustering and Conformational Change in the Adhesive and Signaling Functions of Integrin αIIbβ3
1998
Integrin cytoplasmic domains mediate inside-out signal transduction
1994
Cysteine Proteinases and the Pathogenesis of Amebiasis
2000
Activated Platelets Release Two Types of Membrane Vesicles: Microvesicles by Surface Shedding and Exosomes Derived From Exocytosis of Multivesicular Bodies and -Granules
1999 Standout
Integrins and Signal Transduction Pathways: the Road Taken
1995 StandoutScience
Function and Regulation of the β3 Integrins in Hemostasis and Vascular Biology
1995
Structure of the VHL-ElonginC-ElonginB Complex: Implications for VHL Tumor Suppressor Function
1999 StandoutScienceNobel
Seppuku and Autoimmunity
1992 StandoutScienceNobel
Conformational changes in tertiary structure near the ligand binding site of an integrin I domain
1999
The protein C anticoagulant pathway.
1992
Growth Factors and Cancer
1991 StandoutScience
Endocytosis of GPI-anchored proteins in human lymphocytes: role of glycolipid-based domains, actin cytoskeleton, and protein kinases.
1996
Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains
1996 StandoutNobel
Immunolocalization of beta 1 integrins in platelets and platelet- derived microvesicles
1993
The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens
1998 StandoutScience
Pathophysiologic Implications of Membrane Phospholipid Asymmetry in Blood Cells
1997
In Vivo Transfer of GPI-Linked Complement Restriction Factors from Erythrocytes to the Endothelium
1995 Science
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Protection against Invasive Amebiasis by a Single Monoclonal Antibody Directed against a Lipophosphoglycan Antigen Localized on the Surface of Entamoeba histolytica
1997
Regulatory control of complement on blood platelets
1989
Assembly of the Platelet Prothrombinase Complex Is Linked to Vesiculation of the Platelet Plasma Membrane
1989
Mechanisms and Genes of Cellular Suicide
1995 StandoutScience
Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cells.
1992
Works of PJ Sims being referenced
The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9.
1990
Antileukemic roles of human phospholipid scramblase 1 gene, evidence from inducible PLSCR1-expressing leukemic cells
2006
Inhibition of the complement membrane attack complex by the galactose-specific adhesion of Entamoeba histolytica.
1992
Repolarization of the membrane potential of blood platelets after complement damage: evidence for a Ca++ -dependent exocytotic elimination of C5b-9 pores
1986
Regulatory control of the terminal complement proteins at the surface of human endothelial cells: neutralization of a C5b-9 inhibitor by antibody to CD59
1990
The secretory release reaction initiated by complement proteins C5b-9 occurs without platelet aggregation through glycoprotein IIb-IIIa
1989
Inhibition of homologous complement by CD59 is mediated by a species-selective recognition conferred through binding to C8 within C5b-8 or C9 within C5b-9
1991
Unraveling the Mysteries of Phospholipid Scrambling
2001
Complement proteins C5b-9 stimulate procoagulant activity through platelet prothrombinase
1986
Platelet-derived microparticles express high affinity receptors for factor VIII.
1991
The secretory release reaction initiated by complement proteins C5b-9 occurs without platelet aggregation through glycoprotein IIb-IIIa
1989
Repolarization of the membrane potential of blood platelets after complement damage: evidence for a Ca++ -dependent exocytotic elimination of C5b-9 pores
1986
Effect of platelet activation on the conformation of the plasma membrane glycoprotein IIb-IIIa complex
1991
Elevated platelet-bound IgG associated with an episode of thrombotic thrombocytopenic purpura
1981
Binding of anticoagulant vitamin K-dependent protein S to platelet-derived microparticles
1992
Defective Ca(2+)-induced microvesiculation and deficient expression of procoagulant activity in erythrocytes from a patient with a bleeding disorder: a study of the red blood cells of Scott syndrome
1992
Complement-induced vesiculation and exposure of membrane prothrombinase sites in platelets of paroxysmal nocturnal hemoglobinuria
1993
The interaction of a Ca2+-dependent monoclonal antibody with the protein C activation peptide region. Evidence for obligatory Ca2+ binding to both antigen and antibody.
1988