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Citing Papers
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α
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The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
2004 Standout
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
2005 StandoutScience
The discovery and development of HMG-CoA reductase inhibitors.
1992
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
2009 StandoutNature
In situ click chemistry generation of cyclooxygenase-2 inhibitors
2017 Standout
Risk of Cardiovascular Events Associated With Selective COX-2 Inhibitors
2001
Autophagosomes form at ER–mitochondria contact sites
2013 StandoutNature
Peroxisomal oxidative capacity of brown adipose tissue depends on the thyroid status
1989
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
1998 StandoutNature
Biological basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities
2005
Role of AMP-activated protein kinase in mechanism of metformin action
2001 Standout
Experience with outpatient intravenous teicoplanin therapy for chronic osteomyelitis
1995
Association Between Naproxen Use and Protection Against Acute Myocardial Infarction
2002
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
2008 StandoutNature
A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP
1991 Standout
Vancomycin resistance in staphylococci
1998
Autophagy regulates lipid metabolism
2009 StandoutNature
Risk of cardiovascular events and rofecoxib: cumulative meta-analysis
2004
Comparison of Upper Gastrointestinal Toxicity of Rofecoxib and Naproxen in Patients with Rheumatoid Arthritis
2000 Standout
Osteomyelitis
1997 Standout
Cardiovascular Events Associated with Rofecoxib in a Colorectal Adenoma Chemoprevention Trial
2005 Standout
Juvenile idiopathic arthritis
2007 Standout
Discovery, biochemistry and biology of lovastatin
1988
Effect of Selective Cyclooxygenase 2 Inhibitors and Naproxen on Short-term Risk of Acute Myocardial Infarction in the Elderly
2003
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
1990 StandoutNature
Disulfonimide‐Catalyzed Asymmetric Vinylogous and Bisvinylogous Mukaiyama Aldol Reactions
2010 StandoutNobel
Cardiovascular Risk Associated with Celecoxib in a Clinical Trial for Colorectal Adenoma Prevention
2005 Standout
COX-2 and beyond: approaches to prostaglandin inhibition in human disease
2003
Facilitatory and inhibitory transmitters modulate calcium influx during action potentials in Aplysia sensory neurons
1990 StandoutNobel
A New Equation to Estimate Glomerular Filtration Rate
2009 Standout
Increased hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 in NIDDM
1995
TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival
2003 Standout
Lower Risk of Thromboembolic Cardiovascular Events With Naproxen Among Patients With Rheumatoid Arthritis
2002
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
1998 StandoutNature
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
2014 StandoutNature
Coxibs and Cardiovascular Disease
2004 Standout
Type 2 diabetes
2017 Standout
Diabetes and Atherosclerosis
2002 Standout
Membrane lipids: where they are and how they behave
2008 Standout
Comparison of cardiovascular thrombotic events in patients with osteoarthritis treated with Rofecoxib versus nonselective nonsteroidal anti-inflammatory drugs (Ibuprofen, Diclofenac, and Nabumetone)
2002
Nonsteroidal Anti-Inflammatory drugs and cardiovascular risk
2004
What We Talk About When We Talk About Fat
2014 Standout
Peroxisome proliferating sulphur- and oxy-substituted fatty acid analogues are activated to acyl coenzyme a thioesters
1991
Progress and challenges in translating the biology of atherosclerosis
2011 StandoutNature
The Coxibs, Selective Inhibitors of Cyclooxygenase-2
2001
TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth
2006 Standout
Cyclooxygenase Inhibitors and the Antiplatelet Effects of Aspirin
2001 Standout
World-wide development of antibiotic resistance in pneumococci
1987
Selective COX-2 inhibition and cardiovascular effects: a review of the rofecoxib development program
2003
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
1994 Standout
Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: randomised controlled trial
2004
cPLA2 is phosphorylated and activated by MAP kinase
1993 Standout
The Mechanisms by Which Both Heterozygous Peroxisome Proliferator-activated Receptor γ (PPARγ) Deficiency and PPARγ Agonist Improve Insulin Resistance
2001
Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival
2007 Standout
Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products
2010 Standout
Evaluation of the comparative efficacy and tolerability of rofecoxib and naproxen in children and adolescents with juvenile rheumatoid arthritis: a 12-week randomized controlled clinical trial with a 52-week open-label extension.
2006
Extrusion of Penem Antibiotics by Multicomponent Efflux Systems MexAB-OprM, MexCD-OprJ, and MexXY-OprM of Pseudomonas aeruginosa
2002
Phospholipid synthesis in a membrane fraction associated with mitochondria.
1990
Adipocyte conversion of cultured 3T3-Ll preadipocytes by bezafibrate
1987
Structural and Functional Basis of Cyclooxygenase Inhibition
2007
Type 2 diabetes: principles of pathogenesis and therapy
2005 Standout
Effects of multiple ascending doses of the glucagon receptor antagonist PF ‐06291874 in patients with type 2 diabetes mellitus
2016
Inositol trisphosphate, a novel second messenger in cellular signal transduction
1984 StandoutNature
Prooxidant States and Tumor Promotion
1985 StandoutScience
The Brown Fat Cell
1982
A unique mitochondria-associated membrane fraction from rat liver has a high capacity for lipid synthesis and contains pre-Golgi secretory proteins including nascent lipoproteins.
1994
Diflunisal Analogues Stabilize the Native State of Transthyretin. Potent Inhibition of Amyloidogenesis
2003
Total Synthesis of α-Pyrone Meroterpenoids, Novel Bioactive Microbial Metabolites
2005 StandoutNobel
PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS: A Nuclear Receptor Signaling Pathway in Lipid Physiology
1996
Stimulation of microperoxisomal β-oxidation in rat heart by high-fat diets
1983
Bacterial Resistance to β-Lactam Antibiotics: Compelling Opportunism, Compelling Opportunity
2005 Standout
Antiviral Activity of Lovastatin against Respiratory Syncytial Virus In Vivo and In Vitro
2001
HEPATIC AND RENAL EFFECTS OF PEROXISOME PROLIFERATORS: BIOLOGICAL IMPLICATIONS*
1982
Brown Adipose Tissue: Function and Physiological Significance
2004 Standout
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Drug Discovery: A Historical Perspective
2000 StandoutScience
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
First and Second Generation Total Synthesis of the Teicoplanin Aglycon
2001
Role of Prostacyclin in the Cardiovascular Response to Thromboxane A 2
2002 StandoutScience
Do Fukui Function Maxima Relate to Sites of Metabolism? A Critical Case Study
2005
Dietary Carcinogens and Anticarcinogens
1983 StandoutScience
How is the level of free arachidonic acid controlled in mammalian cells?
1982
Biosynthesis of Apolipoprotein B48-containing Lipoproteins
1996 StandoutNobel
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ
1997 Standout
The Crisis in Antibiotic Resistance
1992 StandoutScience
Effects of high-fat diets on hepatic fatty acid oxidation in the rat Isolation of rat liver peroxisomes by vertical-rotor centrifugation by using a self-generated, iso-osmotic, Percoll gradient
1981
The lipolysis/esterification cycle of hepatic triacylglycerol. Its role in the secretion of very-low-density lipoprotein and its response to hormones and sulphonylureas
1992
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Thermal Atropisomerism of Teicoplanin Aglycon Derivatives: Preparation of the P,P,P and M,P,P Atropisomers of the Teicoplanin Aglycon via Selective Equilibration of the DE Ring System
2000
Drug Prescribing in Renal Failure: Dosing Guidelines for Adults.
1988
Cardiovascular Thrombotic Events in Controlled, Clinical Trials of Rofecoxib
2001
The risk of cardiovascular thrombotic events with selective cyclooxygenase‐2 inhibitors
2002
Extracellular fatty acids are not utilized directly for the synthesis of very-low-density lipoprotein in primary cultures of rat hepatocytes
1992
Works of P.J. De Schepper being referenced
Pharmacokinetics, COX-2 specificity, and tolerability of supratherapeutic doses of rofecoxib in humans
2000
In-vitro metabolism of celecoxib, a cyclooxygenase-2 inhibitor, by allelic variant forms of human liver microsomal cytochrome P450 2C9: correlation with CYP2C9 genotype and in-vivo pharmacokinetics
2001
BIOTRANSFORMATION AND EXCRETION OF LORAZEPAM IN PATIENTS WITH CHRONIC RENAL FAILURE
1976
Comparative pharmacokinetics of piperacillin in normals and in patients with renal failure
1982
Lysosomal triacylglycerol lipase and lipolysis in isolated rat hepatocytes.
1979
In vitro activity and human pharmacokinetics of teicoplanin
1984
Plasma protein binding and interaction studies with diflunisal, a new salicylate analgesic
1980
Mitochondrial and peroxisomal fatty acid oxidation in liver homogenates and isolated hepatocytes from control and clofibrate-treated rats.
1979
Metabolic effects of hypoglycemic sulfonylureas—II
1967
Influence of chronic renal failure and hemodialysis on diflunisal plasma protein binding
1980
Plasma mevalonate as a measure of cholesterol synthesis in man.
1984
Comparative Inhibitory Activity of Rofecoxib, Meloxicam, Diclofenac, Ibuprofen, and Naproxen on COX‐2 versus COX‐1 in Healthy Volunteers
2000
Factors influencing palmitoyl-CoA oxidation by rat liver peroxisomal fractions. Substrate concentration, organelle integrity and ATP
1980