Standout Papers
Citation Impact
Citing Papers
Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
2013 Standout
JNK Expression by Macrophages Promotes Obesity-Induced Insulin Resistance and Inflammation
2012 Science
Increased Adipocyte O2 Consumption Triggers HIF-1α, Causing Inflammation and Insulin Resistance in Obesity
2014
Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling
2015
PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications
2016
FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic–pituitary–adrenal axis
2015
Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses
2018
Regulation of T-cell activation and migration by the kinase TBK1 during neuroinflammation
2015
The PPARγ-FGF1 axis: an unexpected mediator of adipose tissue homeostasis
2012
Brown and Beige Fat: Physiological Roles beyond Heat Generation
2015
Biochemistry and pathophysiology of intravascular and intracellular lipolysis
2013
Diet, gut microbiota and immune responses
2010
Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding
2013
Inflammatory links between obesity and metabolic disease
2011 Standout
A proteolytic pathway that controls glucose uptake in fat and muscle
2013
Leptin revisited: its mechanism of action and potential for treating diabetes
2012
Inhibition of NET Release Fails to Reduce Adipose Tissue Inflammation in Mice
2016
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome
2015 StandoutNature
Hepatic Insulin Resistance Following Chronic Activation of the CREB Coactivator CRTC2
2015
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
Thyroid hormone receptor repression is linked to type I pneumocyte–associated respiratory distress syndrome
2011
Fat tissue, aging, and cellular senescence
2010
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
2012 StandoutNature
Inflammation and Lipid Signaling in the Etiology of Insulin Resistance
2012
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
2011 Standout
Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases
2013
Epigenetic codes of PPARγ in metabolic disease
2011
Considerations and guidelines for mouse metabolic phenotyping in diabetes research
2017
Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075
2021
Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity
2018
NCoR1 Is a Conserved Physiological Modulator of Muscle Mass and Oxidative Function
2011
Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance
2015
Evolution of Inflammation in Nonalcoholic Fatty Liver Disease: The Multiple Parallel Hits Hypothesis
2010 Standout
SMRTε, a corepressor variant, interacts with a restricted subset of nuclear receptors, including the retinoic acid receptors α and β
2012
Obesity Activates a Program of Lysosomal-Dependent Lipid Metabolism in Adipose Tissue Macrophages Independently of Classic Activation
2013
The changing landscape of atherosclerosis
2021 StandoutNature
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
2014 StandoutNature
Local Proliferation of Macrophages Contributes to Obesity-Associated Adipose Tissue Inflammation
2014
Genomic and epigenomic regulation of adipose tissue inflammation in obesity
2013
Homeostasis, Inflammation, and Disease Susceptibility
2015
Immunological Goings-on in Visceral Adipose Tissue
2013
Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes
2016
Newly identified adipose tissue macrophage populations in obesity with distinct chemokine and chemokine receptor expression
2010
Immunological complications of obesity
2012
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
Role of the Microbiota in Immunity and Inflammation
2014 Standout
Chronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 Diabetes
2020
Innate Immune Control of Adipose Tissue Homeostasis
2019
Class II Major Histocompatibility Complex Plays an Essential Role in Obesity-Induced Adipose Inflammation
2013
Deconstructing repression: evolving models of co-repressor action
2010
Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages
2014
Diet–microbiota interactions as moderators of human metabolism
2016 StandoutNature
Emerging roles of the corepressors NCoR1 and SMRT in homeostasis
2013
Functional interactions between the gut microbiota and host metabolism
2012 StandoutNature
Targeting apoptosis in cancer therapy
2020 Standout
Neutrophil extracellular traps in immunity and disease
2017 Standout
Insulin action and resistance in obesity and type 2 diabetes
2017
The Impact of the Gut Microbiota on Human Health: An Integrative View
2012 Standout
NF-κB, Inflammation, and Metabolic Disease
2011 Standout
An Integrated View of Immunometabolism
2018
Insulin Resistance is Associated with MCP1-Mediated Macrophage Accumulation in Skeletal Muscle in Mice and Humans
2014
MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice
2021
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
2016 Standout
Adipocyte-Specific IKKβ Signaling Suppresses Adipose Tissue Inflammation through an IL-13-Dependent Paracrine Feedback Pathway
2014
Trophic macrophages in development and disease
2009
PPARs at the crossroads of lipid signaling and inflammation
2012
The cellular and signaling networks linking the immune system and metabolism in disease
2012
PPARγ signaling and metabolism: the good, the bad and the future
2013 Standout
Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity
2020
Proteasomal degradation of retinoid X receptor α reprograms transcriptional activity of PPARγ in obese mice and humans
2010
The immunomodulating role of exercise in metabolic disease
2014
Adipose Tissue Macrophages Promote Myelopoiesis and Monocytosis in Obesity
2014
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
The Interaction between Nuclear Receptor Corepressor and Histone Deacetylase 3 Regulates Both Positive and Negative Thyroid Hormone Actionin Vivo
2010
Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding
2013
The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43
2013
Chronic tissue inflammation and metabolic disease
2021
Macrophage plasticity and polarization: in vivo veritas
2012 Standout
Local proliferation of macrophages in adipose tissue during obesity-induced inflammation
2013
Mechanisms and Functions of Inflammasomes
2014 Standout
FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages
2010
What We Talk About When We Talk About Fat
2014 Standout
Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity
2017
AKT/PKB Signaling: Navigating the Network
2017 Standout
Knockdown of ANT2 reduces adipocyte hypoxia and improves insulin resistance in obesity
2018
Pharmacology and therapeutics of omega-3 polyunsaturated fatty acids in chronic inflammatory disease
2013
Insulin resistance causes inflammation in adipose tissue
2018
The Hallmarks of Aging
2013 Standout
TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue
2018
Ligand-dependent corepressor acts as a novel corepressor of thyroid hormone receptor and represses hepatic lipogenesis in mice
2011
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Adipose tissue remodeling and obesity
2011
Dietary Regulation of Immunity
2020
Diversity, stability and resilience of the human gut microbiota
2012 StandoutNature
B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
2011
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Hepatic FoxOs Regulate Lipid Metabolism via Modulation of Expression of the Nicotinamide Phosphoribosyltransferase Gene
2011
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells
2012 Nature
Alternative mRNA Splicing of Corepressors Generates Variants That Play Opposing Roles in Adipocyte Differentiation
2011
Interorgan communication by exosomes, adipose tissue, and adiponectin in metabolic syndrome
2019
The resolution code of acute inflammation: Novel pro-resolving lipid mediators in resolution
2015
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
Macrophage-mediated inflammation in metabolic disease
2011
Unravelling mononuclear phagocyte heterogeneity
2010
Neutrophil recruitment and function in health and inflammation
2013 Standout
Associations Among Adipose Tissue Immunology, Inflammation, Exosomes and Insulin Sensitivity in People With Obesity and Nonalcoholic Fatty Liver Disease
2021
SIRT2 negatively regulates insulin resistance in C2C12 skeletal muscle cells
2014
The in vivo role of nuclear receptor corepressors in thyroid hormone action
2012
Inflammation in obesity, diabetes, and related disorders
2022 Standout
Insulin signalling mechanisms for triacylglycerol storage
2013
NK cells link obesity-induced adipose stress to inflammation and insulin resistance
2015
β-arrestin-mediated receptor trafficking and signal transduction
2011 StandoutNobel
Inflammasomes in health and disease
2012 StandoutNature
Altered Interleukin-10 Signaling in Skeletal Muscle Regulates Obesity-Mediated Inflammation and Insulin Resistance
2016
Pleiotropic Actions of Insulin Resistance and Inflammation in Metabolic Homeostasis
2013 Science
Saturated and unsaturated fat induce hepatic insulin resistance independently of TLR-4 signaling and ceramide synthesis in vivo
2013
Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity
2010
Tissue Tregs
2016
Adipose invariant natural killer T cells
2014
The Nuclear Receptor Corepressor (NCoR) Controls Thyroid Hormone Sensitivity and the Set Point of the Hypothalamic-Pituitary-Thyroid Axis
2011
Pro‐Inflammatory macrophages increase in skeletal muscle of high fat‐Fed mice and correlate with metabolic risk markers in humans
2013
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Lymphoid tissue phospholipase A2 group IID resolves contact hypersensitivity by driving antiinflammatory lipid mediators
2013
Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41)
2011
Inflammatory mechanisms linking obesity and metabolic disease
2017
Roles of Chemokines and Chemokine Receptors in Obesity-Associated Insulin Resistance and Nonalcoholic Fatty Liver Disease
2015
Lack of Interleukin-1 Receptor I (IL-1RI) Protects Mice From High-Fat Diet–Induced Adipose Tissue Inflammation Coincident With Improved Glucose Homeostasis
2011
SUMO-1 Regulates Body Weight and Adipogenesis via PPARγ in Male and Female Mice
2012
Diet‐induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonism
2013
Immune Regulation in Obesity-Associated Adipose Inflammation
2013
Metabolically healthy obesity: facts and fantasies
2019
JNK1 and IKKβ: molecular links between obesity and metabolic dysfunction
2010
De Novo Lipogenesis Products and Endogenous Lipokines
2016
Short-term high-fat diet increases macrophage markers in skeletal muscle accompanied by impaired insulin signalling in healthy male subjects
2014
Macrophage Proliferation Sustains Adipose Tissue Inflammation in Formerly Obese Mice
2016
RAGE Regulates the Metabolic and Inflammatory Response to High-Fat Feeding in Mice
2014
Obesity-associated exosomal miRNAs modulate glucose and lipid metabolism in mice
2018
Thyroid Hormone Regulation of Metabolism
2014 Standout
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Inflammatory Mechanisms in Obesity
2011 Standout
Increased Neutrophil Elastase and Proteinase 3 and Augmented NETosis Are Closely Associated With β-Cell Autoimmunity in Patients With Type 1 Diabetes
2014
A Novel Function of Adipocytes in Lipid Antigen Presentation to iNKT Cells
2012
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Regulation of metabolism by the innate immune system
2015
Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue
2018
Deficiency of the Leukotriene B4 Receptor, BLT-1, Protects against Systemic Insulin Resistance in Diet-Induced Obesity
2011
New therapeutic approaches for the treatment of obesity
2016
TRAF2 Ser-11 Phosphorylation Promotes Cytosolic Translocation of the CD40 Complex To Regulate Downstream Signaling Pathways
2020
Role of innate and adaptive immunity in obesity-associated metabolic disease
2017
Emerging Mechanisms of Cardiovascular Protection for the Omega-3 Fatty Acid Eicosapentaenoic Acid
2020
Pro-Inflammatory CD11c+CD206+ Adipose Tissue Macrophages Are Associated With Insulin Resistance in Human Obesity
2010
Endogenous Oils Derived From Human Adipocytes Are Potent Adjuvants That Promote IL-1α–Dependent Inflammation
2014
Adipose Tissue Macrophages Function As Antigen-Presenting Cells and Regulate Adipose Tissue CD4+ T Cells in Mice
2013
B cell–intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice
2021 StandoutNobel
Characterization of Distinct Subpopulations of Hepatic Macrophages in HFD/Obese Mice
2014
Therapeutic Effects of a TANK ‐Binding Kinase 1 Inhibitor in Germinal Center–Driven Collagen‐Induced Arthritis
2018
Interferon Regulatory Factor 4 Regulates Obesity-Induced Inflammation Through Regulation of Adipose Tissue Macrophage Polarization
2013
Inflammation and metabolism in tissue repair and regeneration
2017 StandoutScience
The regulation of glucose metabolism: implications and considerations for the assessment of glucose homeostasis in rodents
2014
SirT1 Regulates Adipose Tissue Inflammation
2011
Macrophages, Inflammation, and Insulin Resistance
2010 Standout
Interleukin-1 signaling contributes to acute islet compensation
2016
Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides
2020 StandoutNobel
Works of Pingping Li being referenced
p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity
2012
Glucocorticoids and Thiazolidinediones Interfere with Adipocyte-mediated Macrophage Chemotaxis and Recruitment
2009
Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance
2016
A PPARγ–FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis
2012 Nature
Ablation of CD11c-Positive Cells Normalizes Insulin Sensitivity in Obese Insulin Resistant Animals
2008
Adipocyte NCoR Knockout Decreases PPARγ Phosphorylation and Enhances PPARγ Activity and Insulin Sensitivity
2011
Functional Heterogeneity of CD11c-positive Adipose Tissue Macrophages in Diet-induced Obese Mice
2010
LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes
2015
GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
2010 Standout
Neuronal Sirt1 Deficiency Increases Insulin Sensitivity in Both Brain and Peripheral Tissues
2013
Regulation of Chemokine and Chemokine Receptor Expression by PPARγ in Adipocytes and Macrophages
2012
An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice
2013
Peroxisome Proliferator-Activated Receptor-γ Transcriptionally Up-Regulates Hormone-Sensitive Lipase via the Involvement of Specificity Protein-1
2005
Palbociclib triggers apoptosis in bladder cancer cells by Cdk2-induced Rad9-mediated reorganization of the Bak.Bcl-xl complex
2019
Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase
2012
NCoR Repression of LXRs Restricts Macrophage Biosynthesis of Insulin-Sensitizing Omega 3 Fatty Acids
2013
Brain PPAR-γ promotes obesity and is required for the insulin–sensitizing effect of thiazolidinediones
2011
Chronic fractalkine administration improves glucose tolerance and pancreatic endocrine function
2018
Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity
2017
Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity
2015
Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling
2017
Novel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetes
2009
FoxO1 Haploinsufficiency Protects Against High-Fat Diet–Induced Insulin Resistance With Enhanced Peroxisome Proliferator–Activated Receptor γ Activation in Adipose Tissue
2009
Inflammation Is Necessary for Long-Term but Not Short-Term High-Fat Diet–Induced Insulin Resistance
2011
SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis
2008